DK0444482T3 - Oxetanoner - Google Patents

Oxetanoner

Info

Publication number
DK0444482T3
DK0444482T3 DK91102151.7T DK91102151T DK0444482T3 DK 0444482 T3 DK0444482 T3 DK 0444482T3 DK 91102151 T DK91102151 T DK 91102151T DK 0444482 T3 DK0444482 T3 DK 0444482T3
Authority
DK
Denmark
Prior art keywords
oxetanones
novel
formula
image
disclosed
Prior art date
Application number
DK91102151.7T
Other languages
English (en)
Inventor
Andre Dr Szente
Romano Dr Derungs
Hans Peter Dr Maerki
Henri Dr Stalder
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0444482T3 publication Critical patent/DK0444482T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/10—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having one or more double bonds between ring members or between ring members and non-ring members
    • C07D305/12—Beta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
DK91102151.7T 1990-02-26 1991-02-15 Oxetanoner DK0444482T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH60490 1990-02-26
CH400590 1990-12-17

Publications (1)

Publication Number Publication Date
DK0444482T3 true DK0444482T3 (da) 1996-05-06

Family

ID=25685091

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91102151.7T DK0444482T3 (da) 1990-02-26 1991-02-15 Oxetanoner

Country Status (18)

Country Link
EP (1) EP0444482B1 (da)
JP (1) JP2753403B2 (da)
KR (1) KR0183036B1 (da)
AT (1) ATE133167T1 (da)
AU (1) AU645291B2 (da)
CA (1) CA2035967C (da)
DE (1) DE59107262D1 (da)
DK (1) DK0444482T3 (da)
ES (1) ES2082869T3 (da)
FI (1) FI115054B (da)
GR (1) GR3019618T3 (da)
HU (1) HU218272B (da)
IE (1) IE72196B1 (da)
IL (1) IL97148A (da)
MC (1) MC2226A1 (da)
NO (1) NO177055C (da)
NZ (1) NZ237170A (da)
PT (1) PT96887B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2035972C (en) * 1990-02-23 2006-07-11 Martin Karpf Process for the preparation of oxetanones
CA2098167C (en) * 1992-06-24 2006-12-19 Dorothea Isler Foodstuffs and feedstuffs containing a lipase inhibitor
NL1004559C2 (nl) * 1996-11-18 1998-05-19 Unilife Boter.
WO2001032670A1 (en) * 1999-10-29 2001-05-10 John Jason Gentry Mullins Oxetanone derivatives
US6342519B2 (en) * 1999-10-29 2002-01-29 2 Pro Chemical Oxetanone derivatives
US6348492B1 (en) * 1999-10-29 2002-02-19 2Pro Chemical Oxetanone derivatives
DE102004009076A1 (de) * 2004-02-23 2005-10-27 Solvay Pharmaceuticals Gmbh Alkylcarbamat-substituierte β-Lactone, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US7074822B2 (en) 2004-02-23 2006-07-11 Solvay Pharmaceuticals Gmbh Alkyl carbamate-substituted β-lactones, process for their preparation, and pharmaceutical compositions containing them
EP2212305A4 (en) * 2007-10-31 2011-10-26 Burnham Inst Medical Research BETA-LACTONE COMPOUNDS
US11339126B2 (en) * 2017-07-12 2022-05-24 Mayo Foundation For Medical Education And Research Compounds for the reducing lipotoxic damage

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS608117B2 (ja) * 1977-02-08 1985-02-28 財団法人微生物化学研究会 新生理活性物質エステラスチンおよびその製造法
GB2023604B (en) * 1978-05-25 1982-07-28 Microbial Chem Res Found Physiologically active derivatives of esterastin and production thereof
JPH0669130B2 (ja) * 1984-08-09 1994-08-31 三菱電機株式会社 遅延線

Also Published As

Publication number Publication date
AU7122891A (en) 1991-08-29
NO910729D0 (no) 1991-02-25
ATE133167T1 (de) 1996-02-15
IL97148A (en) 1996-11-14
PT96887B (pt) 1998-09-30
PT96887A (pt) 1991-10-31
KR0183036B1 (ko) 1999-05-01
MC2226A1 (fr) 1993-02-02
CA2035967C (en) 2001-10-16
HUT56557A (en) 1991-09-30
AU645291B2 (en) 1994-01-13
NO910729L (no) 1991-08-27
FI115054B (fi) 2005-02-28
KR910021391A (ko) 1991-12-20
JPH0770099A (ja) 1995-03-14
EP0444482A2 (de) 1991-09-04
FI910925A (fi) 1991-08-27
FI910925A0 (fi) 1991-02-26
CA2035967A1 (en) 1991-08-27
NO177055B (no) 1995-04-03
IE72196B1 (en) 1997-03-26
NZ237170A (en) 1993-12-23
ES2082869T3 (es) 1996-04-01
EP0444482A3 (en) 1991-12-04
HU218272B (en) 2000-07-28
JP2753403B2 (ja) 1998-05-20
GR3019618T3 (en) 1996-07-31
DE59107262D1 (de) 1996-02-29
IE910631A1 (en) 1991-08-28
IL97148A0 (en) 1992-05-25
NO177055C (no) 1995-07-12
EP0444482B1 (de) 1996-01-17

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment