ES2115916T3 - Procedimiento para la preparacion de compuestos de triazolona. - Google Patents

Procedimiento para la preparacion de compuestos de triazolona.

Info

Publication number
ES2115916T3
ES2115916T3 ES94900112T ES94900112T ES2115916T3 ES 2115916 T3 ES2115916 T3 ES 2115916T3 ES 94900112 T ES94900112 T ES 94900112T ES 94900112 T ES94900112 T ES 94900112T ES 2115916 T3 ES2115916 T3 ES 2115916T3
Authority
ES
Spain
Prior art keywords
preparation
group
procedure
triazolone compounds
rent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94900112T
Other languages
English (en)
Inventor
Alberto Nigro
Mauro Tomaselli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angelini Acraf SpA
Original Assignee
Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco ACRAF SpA filed Critical Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Application granted granted Critical
Publication of ES2115916T3 publication Critical patent/ES2115916T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PREPARACION DE UN COMPONENTE 1,2,4-TRIAZOL-3-ONA SUSTITUIDO EN LAS POSICIONES 4 Y 5 POR UN GRUPO ALQUILO O ARILO Y, OPCIONALMENTE, EN LA POSICION 2 POR UN GRUPO ALQUILO, POR REACCIONAR UN ESTER DE ACIDO CARBAMICO N-SUSTITUIDO POR UN GRUPO ALQUILO O ARILO CON UN HIDRACIDO DE UN ACIDO CARBOXILICO AROMATICO O ALIFATICO, OPCIONALMENTE NSUSTITUIDO POR UN GRUPO ALQUILO, EN LA PRESENCIA DE UNA BASE FUERTE.
ES94900112T 1992-11-13 1993-11-06 Procedimiento para la preparacion de compuestos de triazolona. Expired - Lifetime ES2115916T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI922604A IT1256387B (it) 1992-11-13 1992-11-13 Procedimento per preparare triazoloni

Publications (1)

Publication Number Publication Date
ES2115916T3 true ES2115916T3 (es) 1998-07-01

Family

ID=11364287

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94900112T Expired - Lifetime ES2115916T3 (es) 1992-11-13 1993-11-06 Procedimiento para la preparacion de compuestos de triazolona.

Country Status (9)

Country Link
US (1) US5767275A (es)
EP (1) EP0668857B1 (es)
AT (1) ATE163414T1 (es)
AU (1) AU5464394A (es)
DE (1) DE69317122T2 (es)
DK (1) DK0668857T3 (es)
ES (1) ES2115916T3 (es)
IT (1) IT1256387B (es)
WO (1) WO1994011357A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5625064A (en) * 1995-04-19 1997-04-29 Schering Corporation Process for the preparation of triazolones
CA2182241C (en) * 1996-07-29 2002-09-17 Bo Lei Methods for the manufacture of nefazodone
DE19816882A1 (de) * 1998-04-17 1999-10-21 Boehringer Ingelheim Pharma Triazolone mit neuroprotektiver Wirkung
ES2152860B1 (es) * 1998-10-23 2001-08-16 Finaf 92 Sa Forma cristalina de la nefazodona y procedimiento para su preparacion.
AU4215300A (en) 1999-04-09 2000-11-14 Sepracor, Inc. R-hydroxynefazodone
JP2002541192A (ja) 1999-04-09 2002-12-03 セプラコール， インク． Ｓ−ヒドロキシネファゾドン
WO2013134562A1 (en) 2012-03-09 2013-09-12 Inception 2, Inc. Triazolone compounds and uses thereof
CA2894281C (en) 2012-12-20 2021-04-20 Inception 2, Inc. Triazolone compounds and uses thereof
PE20160880A1 (es) 2013-09-06 2016-09-22 Inception 2 Inc Compuestos de triazolona y usos de los mismos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1545646B1 (de) * 1965-12-15 1969-09-18 Boehringer Sohn Ingelheim 1,3-Dimethyl-4-(2',4'-dichlorphenyl)-1,2,4-triazolon-(5) und Verfahren zu dessen Herstellung
IT1052119B (it) * 1972-10-16 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants
US4596884A (en) * 1983-11-30 1986-06-24 Bristol-Myers Company 4-(2-phenoxyethyl)-1,2,4-triazolone process intermediates
US5094683A (en) * 1988-05-09 1992-03-10 Bayer Aktiengesellschaft Sulphonylaminocarbonyltriazolinones

Also Published As

Publication number Publication date
DE69317122T2 (de) 1998-09-24
DE69317122D1 (de) 1998-04-02
ITMI922604A0 (it) 1992-11-13
AU5464394A (en) 1994-06-08
IT1256387B (it) 1995-12-04
ITMI922604A1 (it) 1994-05-13
EP0668857A1 (en) 1995-08-30
WO1994011357A1 (en) 1994-05-26
US5767275A (en) 1998-06-16
DK0668857T3 (da) 1998-12-07
EP0668857B1 (en) 1998-02-25
ATE163414T1 (de) 1998-03-15

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