DE2336218C3 - Orale Arzneiform - Google Patents

Orale Arzneiform

Info

Publication number
DE2336218C3
DE2336218C3 DE2336218A DE2336218A DE2336218C3 DE 2336218 C3 DE2336218 C3 DE 2336218C3 DE 2336218 A DE2336218 A DE 2336218A DE 2336218 A DE2336218 A DE 2336218A DE 2336218 C3 DE2336218 C3 DE 2336218C3
Authority
DE
Germany
Prior art keywords
weight
active ingredient
drug
release
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2336218A
Other languages
German (de)
English (en)
Other versions
DE2336218B2 (de
DE2336218A1 (de
Inventor
Gerald Dipl.-Chem. Dr. 7750 Konstanz Benedikt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Byk Gulden Lomberg Chemische Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chemische Fabrik GmbH filed Critical Byk Gulden Lomberg Chemische Fabrik GmbH
Priority to DE2336218A priority Critical patent/DE2336218C3/de
Priority to US05/486,432 priority patent/US4083949A/en
Priority to FR7424615A priority patent/FR2237620B1/fr
Priority to NL7409597.A priority patent/NL165651C/xx
Priority to CH979074A priority patent/CH595841A5/xx
Priority to GB3164274A priority patent/GB1469133A/en
Priority to AT593274A priority patent/AT342203B/de
Priority to BE146628A priority patent/BE817732A/xx
Priority to JP49082097A priority patent/JPS593447B2/ja
Publication of DE2336218A1 publication Critical patent/DE2336218A1/de
Publication of DE2336218B2 publication Critical patent/DE2336218B2/de
Application granted granted Critical
Publication of DE2336218C3 publication Critical patent/DE2336218C3/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2336218A 1973-07-17 1973-07-17 Orale Arzneiform Expired DE2336218C3 (de)

Priority Applications (9)

Application Number Priority Date Filing Date Title
DE2336218A DE2336218C3 (de) 1973-07-17 1973-07-17 Orale Arzneiform
US05/486,432 US4083949A (en) 1973-07-17 1974-07-08 New oral form of medicament and a method for producing it
NL7409597.A NL165651C (nl) 1973-07-17 1974-07-16 Werkwijze ter bereiding van een oraal depotgeneesmiddel.
CH979074A CH595841A5 (cg-RX-API-DMAC7.html) 1973-07-17 1974-07-16
FR7424615A FR2237620B1 (cg-RX-API-DMAC7.html) 1973-07-17 1974-07-16
GB3164274A GB1469133A (en) 1973-07-17 1974-07-17 Oral form of medicament and a method for producing it
AT593274A AT342203B (de) 1973-07-17 1974-07-17 Verfahren zur herstellung einer neuen oralen depot-arzneiform
BE146628A BE817732A (fr) 1973-07-17 1974-07-17 Nouvelle forme galenique d'administration de medicaments par voie orale et son procede de fabrication
JP49082097A JPS593447B2 (ja) 1973-07-17 1974-07-17 持続性経口薬剤の製法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2336218A DE2336218C3 (de) 1973-07-17 1973-07-17 Orale Arzneiform

Publications (3)

Publication Number Publication Date
DE2336218A1 DE2336218A1 (de) 1975-02-06
DE2336218B2 DE2336218B2 (de) 1979-05-17
DE2336218C3 true DE2336218C3 (de) 1985-11-14

Family

ID=5887126

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2336218A Expired DE2336218C3 (de) 1973-07-17 1973-07-17 Orale Arzneiform

Country Status (9)

Country Link
US (1) US4083949A (cg-RX-API-DMAC7.html)
JP (1) JPS593447B2 (cg-RX-API-DMAC7.html)
AT (1) AT342203B (cg-RX-API-DMAC7.html)
BE (1) BE817732A (cg-RX-API-DMAC7.html)
CH (1) CH595841A5 (cg-RX-API-DMAC7.html)
DE (1) DE2336218C3 (cg-RX-API-DMAC7.html)
FR (1) FR2237620B1 (cg-RX-API-DMAC7.html)
GB (1) GB1469133A (cg-RX-API-DMAC7.html)
NL (1) NL165651C (cg-RX-API-DMAC7.html)

Families Citing this family (147)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2377196A1 (fr) * 1977-01-13 1978-08-11 Lipha Composition medicamenteuse a usage oral
US4218433A (en) * 1977-03-03 1980-08-19 Nippon Kayaku Kabushiki Kaisha Constant-rate eluting tablet and method of producing same
GB1561204A (en) * 1977-06-01 1980-02-13 Ici Ltd Sustained release pharmaceutical composition
FR2397840B1 (cg-RX-API-DMAC7.html) * 1977-07-22 1981-03-20 Cherqui Jean
US4220153A (en) * 1978-05-08 1980-09-02 Pfizer Inc. Controlled release delivery system
US4220152A (en) * 1978-05-08 1980-09-02 Pfizer Inc. Delivery system
US4153677A (en) * 1978-05-18 1979-05-08 Sterling Drug Inc. Controlled-release composition
GB1584130A (en) * 1978-05-30 1981-02-04 Wyeth John & Brother Ltd Indole derivatives
DD146547A5 (de) * 1978-07-15 1981-02-18 Boehringer Sohn Ingelheim Arzneimittel-retardform mit unloeslichen poroesen diffusionshuellen
SE426548B (sv) * 1978-12-05 1983-01-31 Haessle Ab Fast farmaceutisk beredning innehallande en terapeutiskt effektiv hjertglykosid och en polymer
US4173626A (en) * 1978-12-11 1979-11-06 Merck & Co., Inc. Sustained release indomethacin
SE7813246L (sv) * 1978-12-22 1980-06-23 Haessle Ab Fast farmaceutisk beredning innehallande kroppar med flera ytskikt
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
FR2454804B1 (fr) * 1979-04-26 1986-11-21 Sanofi Sa Medicament a base de dihydroergotoxine et son procede de preparation
FR2470599A1 (fr) * 1979-12-07 1981-06-12 Panoz Donald Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
DE3000979A1 (de) 1980-01-12 1981-07-23 Dr. Karl Thomae Gmbh, 7950 Biberach Neue dipyridamol-retardformen und verfahren zu ihrer herstellung
EP0052076B1 (de) * 1980-11-12 1985-05-29 Ciba-Geigy Ag Schnellzerfallende Arzneimittel-Presslinge
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
FR2494112B1 (cg-RX-API-DMAC7.html) * 1980-11-19 1986-01-10 Laruelle Claude
ATE14379T1 (de) * 1981-04-27 1985-08-15 Haessle Ab Pharmazeutisches praeparat.
ZA822995B (en) * 1981-05-21 1983-12-28 Wyeth John & Brother Ltd Slow release pharmaceutical composition
DE3126703A1 (de) 1981-07-07 1983-01-27 Dr. Karl Thomae Gmbh, 7950 Biberach Bromhexin-retardform und verfahren zu ihrer herstellung
EP0083372B1 (en) * 1981-07-15 1988-05-18 Key Pharmaceuticals, Inc. Sustained release theophyline
ZA825384B (en) * 1981-07-31 1983-05-25 Tillott J B Ltd Orally administrable pharmaceutical compositions
JPS5867616A (ja) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd 腸溶性マイクロカプセル
US4370313A (en) * 1981-10-26 1983-01-25 Eaton Laboratories, Inc. Nitrofurantoin dosage form
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
DE3214667C2 (de) * 1982-04-21 1985-07-18 Akzo Gmbh, 5600 Wuppertal Zusammengesetzter Körper für die Langzeitabgabe von Wirkstoffen
US4508702A (en) * 1982-06-14 1985-04-02 Key Pharmaceuticals, Inc. Sustained release aspirin
US4415547A (en) * 1982-06-14 1983-11-15 Sterling Drug Inc. Sustained-release pharmaceutical tablet and process for preparation thereof
EP0111560A4 (en) * 1982-06-14 1987-02-03 Key Pharma Sustained release aspirin.
US4557925A (en) * 1982-07-08 1985-12-10 Ab Ferrosan Membrane-coated sustained-release tablets and method
US4634587A (en) * 1982-07-09 1987-01-06 Key Pharmaceuticals, Inc. Sustained release quinidine dosage form
DE3382392D1 (de) * 1982-07-09 1991-10-02 Key Pharma Dosierungsart zur dauerhaften verabreichung von chinidin.
US4704284A (en) * 1982-08-12 1987-11-03 Pfizer Inc. Long-acting matrix tablet formulations
US4522625A (en) * 1982-09-29 1985-06-11 Alza Corporation Drug dispenser comprising wall formed of semipermeable member and enteric member
IE55745B1 (en) * 1983-04-06 1991-01-02 Elan Corp Plc Sustained absorption pharmaceutical composition
HU191542B (en) * 1983-04-08 1987-03-30 Boehringer Ingelheim Ltd Process for production of pastiles containing dipyridamel independent from ph with regulated output of the active substance
JPS6051106A (ja) * 1983-08-31 1985-03-22 Yamanouchi Pharmaceut Co Ltd 塩酸アモスラロ−ル持続性製剤
US4749575A (en) * 1983-10-03 1988-06-07 Bio-Dar Ltd. Microencapsulated medicament in sweet matrix
US4555399A (en) * 1983-11-18 1985-11-26 Key Pharmaceuticals, Inc. Aspirin tablet
DE3403329A1 (de) * 1984-02-01 1985-08-01 Horst Dr. 4019 Monheim Zerbe Pharmazeutisches produkt in form von pellets mit kontinuierlicher, verzoegerter wirkstoffabgabe
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat
JPS60221078A (ja) * 1984-04-18 1985-11-05 Morinaga Milk Ind Co Ltd 有用微生物粉末の粒状製品およびその製造法
GB2159714B (en) * 1984-06-04 1988-05-05 Sterwin Ag Pharmaceutical composition of sparingly soluble medicament and method for its preparation
GB8414221D0 (en) * 1984-06-04 1984-07-11 Sterwin Ag Unit dosage form
US4629619A (en) * 1984-09-05 1986-12-16 Ab Ferrosan Membrane-coated sustained-release tablets and method
US4629620A (en) * 1984-09-05 1986-12-16 Ab Ferrosan Membrane-coated sustained-release tablets and method
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4867984A (en) * 1984-11-06 1989-09-19 Nagin K. Patel Drug in bead form and process for preparing same
IE58246B1 (en) * 1984-12-21 1993-08-11 Byk Gulden Lomberg Chem Fab Theophylline sustained release formulation
US5069911A (en) * 1985-02-05 1991-12-03 Sandoz Ltd. Pharmaceutical 9,10-dihydrogenated ergot alkaloid containing compositions
EP0207638B1 (en) * 1985-06-04 1990-12-19 Teijin Limited Sustained-release pharmaceutical preparation
GB8519310D0 (en) * 1985-07-31 1985-09-04 Zyma Sa Granular active substances
GB8521494D0 (en) * 1985-08-29 1985-10-02 Zyma Sa Controlled release tablet
SE455836B (sv) * 1985-10-11 1988-08-15 Haessle Ab Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning
DE3610878A1 (de) * 1986-04-01 1987-10-08 Boehringer Ingelheim Kg Formlinge aus pellets
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
IT1200217B (it) * 1986-09-30 1989-01-05 Valducci Roberto Membrana per uso farmaceutico ed industriale
IT1197316B (it) * 1986-10-01 1988-11-30 Proter Spa Formulazione galenica ad uso orale di derivati della reina a lento rilascio per impiego terapeutico
US4752470A (en) * 1986-11-24 1988-06-21 Mehta Atul M Controlled release indomethacin
IL84599A0 (en) * 1986-12-09 1988-04-29 Byk Gulden Lomberg Chem Fab Pharmaceutical composition containing urapidil and process for the preparation thereof
SE460946B (sv) * 1987-03-16 1989-12-11 Lejus Medical Ab En multipel-unit-dos komposition av kinidinglukonat
US5200193A (en) * 1987-04-22 1993-04-06 Mcneilab, Inc. Pharmaceutical sustained release matrix and process
US4786509A (en) * 1987-05-18 1988-11-22 Schering Corporation Dry sustained release theophylline oral formulation
SE8703881D0 (sv) * 1987-10-08 1987-10-08 Haessle Ab New pharmaceutical preparation
US4925675A (en) * 1988-08-19 1990-05-15 Himedics, Inc. Erythromycin microencapsulated granules
US4925674A (en) * 1988-08-25 1990-05-15 Himedics, Inc. Amoxicillin microencapsulated granules
US5196203A (en) * 1989-01-06 1993-03-23 F. H. Faulding & Co. Limited Theophylline dosage form
US5202128A (en) * 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
US5122384A (en) * 1989-05-05 1992-06-16 Kv Pharmaceutical Company Oral once-per-day organic nitrate formulation which does not induce tolerance
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US4983401A (en) * 1989-05-22 1991-01-08 Kinaform Technology, Inc. Sustained release pharmaceutical preparations having pH controlled membrane coatings
US4966770A (en) * 1989-07-26 1990-10-30 Himedics, Inc. Prednisone microencapsulated granules
AU8941491A (en) * 1990-11-27 1992-06-25 Byk Gulden Lomberg Chemische Fabrik Gmbh Retarded-action urapidil formulation
US6638963B1 (en) 1990-12-04 2003-10-28 Oregon Health And Science University Methods for treating circadian rhythm disorders
US5707652A (en) * 1990-12-04 1998-01-13 State Of Oregon Methods of treating circadian rhythm phase disorders
US5162110A (en) * 1990-12-19 1992-11-10 Rhone-Poulenc Rorer Pharmaceuticals Inc. Binding theophylline to ion exchange resins
SG42869A1 (en) * 1992-08-05 1997-10-17 Faulding F H & Co Ltd Pelletised pharmaceutical composition
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
US6262115B1 (en) * 1995-05-22 2001-07-17 Alza Coporation Method for the management of incontinence
US5912268A (en) * 1995-05-22 1999-06-15 Alza Corporation Dosage form and method for treating incontinence
US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
US6245351B1 (en) * 1996-03-07 2001-06-12 Takeda Chemical Industries, Ltd. Controlled-release composition
ZA977873B (en) * 1996-09-30 1998-04-23 Alza Corp Dosage form and method for administering drug.
CA2264852C (en) * 1996-09-30 2005-11-01 Alza Corporation Use of methylphenidate or a pharmaceutically acceptable salt thereof
US6919373B1 (en) * 1996-11-12 2005-07-19 Alza Corporation Methods and devices for providing prolonged drug therapy
US20020182258A1 (en) * 1997-01-22 2002-12-05 Zycos Inc., A Delaware Corporation Microparticles for delivery of nucleic acid
US20040062799A1 (en) * 1997-09-29 2004-04-01 Ayer Atul D. Therapeutic composition and delivery system for administering drug
ATE292961T1 (de) * 1998-07-28 2005-04-15 Tanabe Seiyaku Co Zur wirkstoffabgabe an zielorten im darm fähige zubereitung
AU781048B2 (en) * 1999-09-02 2005-05-05 Nostrum Pharmaceuticals, Inc. Controlled release pellet formulation
US20050037086A1 (en) * 1999-11-19 2005-02-17 Zycos Inc., A Delaware Corporation Continuous-flow method for preparing microparticles
AU6815901A (en) * 2000-06-02 2001-12-17 Zycos Inc Delivery systems for bioactive agents
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) * 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
ATE380029T1 (de) * 2001-06-11 2007-12-15 Xenoport Inc Prodrugs von gaba-analoga, zusammensetzungen und ihre verwendungszwecke
EP1412324A4 (en) * 2001-06-11 2004-09-29 Xenoport Inc AMINO ACID CONJUGATES THAT RESULT IN GABA ANALOGA LASTING SYSTEMIC CONCENTRATIONS
AP1919A (en) * 2001-11-21 2008-11-13 Eisai R&D Man Co Ltd Preparation compositions containing acid-unstable physiologically active compounds and process for producing the same
US20050163846A1 (en) * 2001-11-21 2005-07-28 Eisai Co., Ltd. Preparation composition containing acid-unstable physiologically active compound, and process for producing same
US20050208132A1 (en) * 2002-07-29 2005-09-22 Gayatri Sathyan Methods and dosage forms for reducing side effects of benzisozazole derivatives
US20050232995A1 (en) * 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
US20040029959A1 (en) * 2002-08-08 2004-02-12 John Devane Isosorbide mononitrate compositions and methods of their use
AU2003293423A1 (en) 2002-12-06 2004-06-30 Xenoport, Inc. Carbidopa prodrugs and uses thereof
US20040162351A1 (en) * 2002-12-11 2004-08-19 Gallop Mark A. Orally administered dosage forms of fused GABA analog prodrugs having reduced toxicity
CA2520468A1 (en) 2003-03-31 2004-10-21 Xenoport, Inc. Treating or preventing hot flashes using prodrugs of gaba analogs
KR20110097942A (ko) 2003-08-20 2011-08-31 제노포트 인코포레이티드 아실옥시알킬 카르바메이트 프로드러그, 합성 및 사용 방법
EP2354120A1 (en) 2003-08-20 2011-08-10 XenoPort, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
EP1670451A4 (en) * 2003-09-11 2009-10-21 Xenoport Inc TREATMENT AND / OR PREVENTION OF URINARY INCONTINENCE AND PROMOTERS OF GABA ANALOGS
NZ545989A (en) * 2003-09-17 2009-10-30 Xenoport Inc Treating or preventing restless legs syndrome using prodrugs of gaba analogs
US7943585B2 (en) * 2003-12-22 2011-05-17 Sandoz, Inc. Extended release antibiotic composition
MY139427A (en) * 2004-03-26 2009-09-30 Eisai R&D Man Co Ltd Controlled-release pharmaceutical composition and method for producing the same
RU2365580C2 (ru) * 2004-06-04 2009-08-27 Ксенопорт, Инк. Пролекарства леводопа, композиции на их основе и их применения
WO2005121070A1 (en) * 2004-06-04 2005-12-22 Xenoport, Inc. Levodopa prodrugs, and compositions and uses thereof
US20060128676A1 (en) * 2004-07-13 2006-06-15 Pharmacofore, Inc. Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain
JP2008515787A (ja) * 2004-10-05 2008-05-15 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング プロトンポンプアンタゴニストと塩基性賦形剤とを含有する経口医薬調剤
US7566738B2 (en) * 2004-11-03 2009-07-28 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
WO2006050472A2 (en) * 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous and -phosphinic acids
CN102429882B (zh) * 2004-11-04 2015-03-25 什诺波特有限公司 加巴喷丁前体药物持续释放口服剂型
AU2006216646B2 (en) 2005-02-23 2012-05-31 Prexa Pharmaceuticals, Inc. Dopamine transporter inhibitors for use in treatment of movement disorders and other cns indications
US7208611B2 (en) * 2005-02-23 2007-04-24 Xenoport, Inc. Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
CN101253148B (zh) 2005-06-20 2013-01-02 克塞诺波特公司 凝血酸的酰氧基烷基氨基甲酸酯前药，合成和使用的方法
US20060293218A1 (en) * 2005-06-22 2006-12-28 Meythaler Jay M Salicylate therapeutic compound and process for controlled delivery thereof
US20070049626A1 (en) * 2005-08-26 2007-03-01 Tran Pierre V Treating premature ejaculation using gabapentin and pregabalin prodrugs
EP1930030A1 (en) * 2005-09-29 2008-06-11 Eisai R&D Management Co., Ltd. Pulse preparation having improved disintegration properties in vivo
PT1959948E (pt) * 2005-12-05 2012-09-12 Xenoport Inc Mesilato de pró-fármaco de levodopa, suas composições e suas utilizações
KR101489401B1 (ko) * 2006-01-27 2015-02-03 앱탈리스 파마테크, 인코포레이티드 약 염기성 약물과 유기산을 포함하는 약물 전달 시스템
EP1976491B1 (en) * 2006-01-27 2014-12-17 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic selective serotonin 5-ht3 blocking agent and organic acids
ES2456674T3 (es) 2006-05-26 2014-04-23 Signature Therapeutics, Inc. Liberación controlada de opioides fenólicos
WO2008027557A2 (en) * 2006-08-31 2008-03-06 Spherics, Inc. Topiramate compositions and methods of enhancing its bioavailability
US7585996B2 (en) * 2006-09-15 2009-09-08 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
WO2008062320A2 (en) * 2006-10-06 2008-05-29 Eisai R&D Management Co., Ltd Extended release formulations of a proton pump inhibitor
AU2007319141B2 (en) 2006-11-17 2013-01-10 Supernus Pharmaceuticals Inc. Sustained-release formulations of topiramate
CA2672044A1 (en) * 2006-12-08 2008-06-19 Xenoport, Inc. Use of prodrugs of gaba analogs for treating diseases
TW200843732A (en) * 2006-12-21 2008-11-16 Xenoport Inc Levodopa dimethyl-substituted diester prodrugs, compositions, and methods of use
WO2008079387A1 (en) * 2006-12-21 2008-07-03 Xenoport, Inc. Catechol protected levodopa diester prodrugs, compositions, and methods of use
US8133506B2 (en) * 2008-03-12 2012-03-13 Aptalis Pharmatech, Inc. Drug delivery systems comprising weakly basic drugs and organic acids
US8399513B2 (en) * 2008-10-20 2013-03-19 Xenoport, Inc. Levodopa prodrug mesylate hydrate
WO2010047775A2 (en) * 2008-10-20 2010-04-29 Xenoport, Inc. Methods of synthesizing a levodopa ester prodrug
WO2010118362A1 (en) 2009-04-09 2010-10-14 The Regents Of The University Of Colorado, A Body Corporate Methods and compositions for inducing physiological hypertrophy
US20110003005A1 (en) * 2009-07-06 2011-01-06 Gopi Venkatesh Methods of Treating PDNV and PONV with Extended Release Ondansetron Compositions
US20110060040A1 (en) * 2009-09-04 2011-03-10 Xenoport, Inc. Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
AU2010315892B2 (en) 2009-11-09 2014-09-18 Xenoport, Inc. Pharmaceutical compositions and oral dosage forms of a levodopa prodrug and methods of use
CA2936748C (en) 2014-10-31 2017-08-08 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
JP2018534269A (ja) 2015-10-01 2018-11-22 エリージウム セラピューティクス， インコーポレイテッド 過剰摂取および乱用に抵抗性のポリサブユニットオピオイドプロドラッグ
US10335406B2 (en) 2015-10-01 2019-07-02 Elysium Therapeutics, Inc. Opioid compositions resistant to overdose and abuse
WO2018170465A1 (en) 2017-03-17 2018-09-20 Elysium Therapeutics, Inc. Polysubunit opioid prodrugs resistant to overdose and abuse
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2921883A (en) * 1957-05-03 1960-01-19 Smith Kline French Lab Novel coating material for medicaments
GB887682A (en) * 1958-10-22 1962-01-24 Upjohn Co Improvements in or relating to medicinal coating compositions
US3247066A (en) * 1962-09-12 1966-04-19 Parke Davis & Co Controlled release dosage form containing water-swellable beadlet
US3282790A (en) * 1963-05-31 1966-11-01 Upjohn Co Enteric coated tablet
IL27218A (en) * 1966-01-17 1970-05-21 Aerojet General Co Reverse osmosis and membrane manufacture
US3567809A (en) * 1966-10-07 1971-03-02 Fuji Photo Film Co Ltd Method of varying the pore diameters of fine pores in cellulose acetate film
US3538214A (en) * 1969-04-22 1970-11-03 Merck & Co Inc Controlled release medicinal tablets
US3593855A (en) * 1969-05-13 1971-07-20 Westinghouse Electric Corp High flow porous reverse osmosis membranes containing lipids
US3648845A (en) * 1969-09-02 1972-03-14 Us Interior Thin film separation membranes and processes for making same
DE2010416B2 (de) * 1970-03-05 1979-03-29 Hoechst Ag, 6000 Frankfurt Oral anwendbare Arzneiform mit Retardwirkung
CA952431A (en) * 1970-09-28 1974-08-06 Frank M. Bardani Controlled release medicament
JPS5518694B2 (cg-RX-API-DMAC7.html) * 1973-04-02 1980-05-21

Also Published As

Publication number Publication date
CH595841A5 (cg-RX-API-DMAC7.html) 1978-02-28
AT342203B (de) 1978-03-28
US4083949A (en) 1978-04-11
NL165651C (nl) 1981-05-15
JPS593447B2 (ja) 1984-01-24
DE2336218B2 (de) 1979-05-17
GB1469133A (en) 1977-03-30
ATA593274A (de) 1977-07-15
FR2237620A1 (cg-RX-API-DMAC7.html) 1975-02-14
NL7409597A (nl) 1975-01-21
BE817732A (fr) 1975-01-17
DE2336218A1 (de) 1975-02-06
JPS5040719A (cg-RX-API-DMAC7.html) 1975-04-14
FR2237620B1 (cg-RX-API-DMAC7.html) 1978-07-28
NL165651B (nl) 1980-12-15

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