DE2265666C2 - Pleuromutilin-Derivate, deren Herstellung und pharmazeutische Zubereitung - Google Patents

Pleuromutilin-Derivate, deren Herstellung und pharmazeutische Zubereitung

Info

Publication number
DE2265666C2
DE2265666C2 DE2265666A DE2265666A DE2265666C2 DE 2265666 C2 DE2265666 C2 DE 2265666C2 DE 2265666 A DE2265666 A DE 2265666A DE 2265666 A DE2265666 A DE 2265666A DE 2265666 C2 DE2265666 C2 DE 2265666C2
Authority
DE
Germany
Prior art keywords
formula
alkyl
compound
nitrogen atom
above meaning
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2265666A
Other languages
German (de)
English (en)
Inventor
Helmut Dr. Wien Egger
Hellmuth Dr. 7801 Hartheim Reinshagen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz Patent GmbH
Original Assignee
Sandoz Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27509313&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE2265666(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from CH1445071A external-priority patent/CH560180A5/de
Priority claimed from CH1445171A external-priority patent/CH559719A5/de
Priority claimed from CH773872A external-priority patent/CH572893A5/xx
Priority claimed from CH774072A external-priority patent/CH575375A5/de
Priority claimed from CH773972A external-priority patent/CH568272A5/de
Application filed by Sandoz Patent GmbH filed Critical Sandoz Patent GmbH
Application granted granted Critical
Publication of DE2265666C2 publication Critical patent/DE2265666C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE2265666A 1971-10-05 1972-10-02 Pleuromutilin-Derivate, deren Herstellung und pharmazeutische Zubereitung Expired DE2265666C2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CH1445071A CH560180A5 (en) 1971-10-05 1971-10-05 Pleuromutilin derivs - with antibacterial activity
CH1445171A CH559719A5 (en) 1971-10-05 1971-10-05 Pleuromutilin derivs - with antibacterial activity
CH773872A CH572893A5 (en) 1972-05-25 1972-05-25 Pleuromutilin derivs - with antibacterial activity
CH774072A CH575375A5 (hu) 1972-05-25 1972-05-25
CH773972A CH568272A5 (en) 1972-05-25 1972-05-25 (Para-substd phenoxy- or phenylthio-acetoxy)-pleuromutilin deriv - prepd by reacting para-hydroxy or-mercapto cpds with e.g. aminoalkyl halides

Publications (1)

Publication Number Publication Date
DE2265666C2 true DE2265666C2 (de) 1983-02-03

Family

ID=27509313

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2265666A Expired DE2265666C2 (de) 1971-10-05 1972-10-02 Pleuromutilin-Derivate, deren Herstellung und pharmazeutische Zubereitung
DE2248237A Expired DE2248237C2 (de) 1971-10-05 1972-10-02 Pleuromutilin-Derivate, deren Herstellung und pharmazeutische Zubereitung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE2248237A Expired DE2248237C2 (de) 1971-10-05 1972-10-02 Pleuromutilin-Derivate, deren Herstellung und pharmazeutische Zubereitung

Country Status (20)

Country Link
US (1) US4278674A (hu)
JP (1) JPS577147B2 (hu)
BE (1) BE789629A (hu)
BG (2) BG21386A3 (hu)
CA (1) CA979447A (hu)
DD (1) DD100706A5 (hu)
DE (2) DE2265666C2 (hu)
DK (1) DK139720B (hu)
FI (1) FI58635C (hu)
FR (1) FR2157828B1 (hu)
GB (1) GB1410505A (hu)
HU (1) HU168436B (hu)
IE (1) IE37699B1 (hu)
IL (1) IL40494A (hu)
NL (1) NL177403C (hu)
NO (3) NO136459C (hu)
OA (1) OA04192A (hu)
PH (1) PH11870A (hu)
RO (2) RO67479A (hu)
SE (3) SE398348B (hu)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3987194A (en) * 1975-05-12 1976-10-19 E. R. Squibb & Sons, Inc. Use of pleuromutilin derivatives for the treatment of swine dysentery
FR2428030A1 (fr) * 1978-06-06 1980-01-04 Sandoz Sa Procede de preparation de derives de la pleuromutiline
JPS56168463A (en) * 1980-05-30 1981-12-24 Iwao Koyama Telephone set
LU82738A1 (fr) * 1980-08-29 1982-05-10 Continental Pharma Derives d'aminothiols,leur preparation et utilisation ainsi que compositions contenant ces derives
JPS60121870A (ja) * 1983-12-06 1985-06-29 Matsushita Electric Ind Co Ltd インタ−ホン装置
JPS62137952A (ja) * 1985-12-12 1987-06-20 Sakuragi Kunio 電話機
JPH0418190Y2 (hu) * 1986-09-19 1992-04-23
JPH01105238U (hu) * 1988-01-05 1989-07-14
CZ212498A3 (cs) * 1996-01-03 1998-12-16 Smithkline Beecham P. L. C. Karbamoyloxyderiváty mutilinu, způsob výroby a farmaceutický prosředek
FR2746012B1 (fr) * 1996-03-13 1998-05-22 Utilisation de la tiamuline pour la preparation d'un medicament comme agent de reversion de la multichimioresistance cancereuse
UY25225A1 (es) * 1997-10-29 2000-12-29 Smithkline Beecham Plc Derivados de pleuromutilina utiles como agentes antimicrobianos
WO2000027790A1 (en) * 1998-11-11 2000-05-18 Smithkline Beecham P.L.C. Mutilin compounds
WO2000037074A1 (en) * 1998-12-18 2000-06-29 Smithkline Beecham Plc Mutilin 14-ester derivatives having antibacterial activity
GB9912657D0 (en) * 1999-06-01 1999-07-28 Smithkline Beecham Plc Novel compounds
GB9918037D0 (en) * 1999-07-30 1999-09-29 Biochemie Gmbh Organic compounds
GB0017031D0 (en) * 2000-07-11 2000-08-30 Biochemie Gmbh Antimicrobials
PE20020676A1 (es) * 2000-09-13 2002-08-27 Biochemie Gmbh Compuestos de mutilina como antibacterianos
GB0207495D0 (en) * 2002-03-28 2002-05-08 Biochemie Gmbh Organic compounds
GB0308114D0 (en) * 2003-04-08 2003-05-14 Glaxo Group Ltd Novel compounds
ES2335284T3 (es) * 2003-09-03 2010-03-24 Glaxo Group Limited Nuevo procedimiento para preparar derivados de pleuromutilina.
GB0504314D0 (en) * 2005-03-02 2005-04-06 Glaxo Group Ltd Novel polymorph
US20080171766A1 (en) * 2005-03-10 2008-07-17 Smithkline Beecham Corporation Novel Method
GB0513058D0 (en) * 2005-06-27 2005-08-03 Sandoz Ag Organic compounds
EP1808431A1 (en) * 2006-01-16 2007-07-18 Nabriva Therapeutics Forschungs GmbH Mutilin derivatives and their use as pharmaceutical
WO2008117796A1 (ja) * 2007-03-28 2008-10-02 Dainippon Sumitomo Pharma Co., Ltd. 新規ムチリン誘導体
CN101434567B (zh) * 2008-12-19 2012-10-24 李扬 一种二乙氨基乙硫醇的制备方法
CN103709115A (zh) * 2012-10-09 2014-04-09 山东亨利医药科技有限责任公司 截短侧耳素类抗生素衍生物
NZ707752A (en) 2012-12-03 2020-01-31 Pfizer Novel selective androgen receptor modulators
CN104447449B (zh) * 2014-12-30 2016-06-15 陕西师范大学 一锅法合成泰妙菌素的方法
CN110981769B (zh) * 2019-12-19 2022-02-18 江苏威凌生化科技有限公司 一种制备泰秒菌素的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7010444A (hu) * 1969-07-25 1971-01-27

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107164A (en) * 1971-10-05 1978-08-15 Sandoz Ltd. Certain pleuromulilin ester derivatives
US4032530A (en) * 1971-10-05 1977-06-28 Sandoz Ltd. Certain pleuromutilins
US3919290A (en) * 1972-10-03 1975-11-11 Sandoz Ltd Substituted 14-desoxy-mutilins

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7010444A (hu) * 1969-07-25 1971-01-27

Also Published As

Publication number Publication date
NL177403C (nl) 1985-09-16
SE398348B (sv) 1977-12-19
SE7509457L (sv) 1975-08-26
BG20773A3 (hu) 1975-12-20
BE789629A (fr) 1973-04-03
JPS577147B2 (hu) 1982-02-09
FR2157828B1 (hu) 1975-11-28
NO136837B (no) 1977-08-08
IE37699L (en) 1973-04-05
HU168436B (hu) 1976-04-28
IL40494A (en) 1976-01-30
PH11870A (en) 1978-08-04
CA979447A (en) 1975-12-09
NO136837C (no) 1977-11-16
OA04192A (fr) 1979-12-31
JPS4844244A (hu) 1973-06-26
IL40494A0 (en) 1972-12-29
IE37699B1 (en) 1977-09-28
DK139720B (da) 1979-04-02
NL177403B (nl) 1985-04-16
FI58635C (fi) 1981-03-10
NL7213254A (hu) 1973-04-09
NO137440B (no) 1977-11-21
SE424074B (sv) 1982-06-28
NO137440C (no) 1978-03-01
DE2248237A1 (de) 1973-04-12
US4278674A (en) 1981-07-14
DK139720C (hu) 1979-10-01
DD100706A5 (hu) 1973-10-05
FI58635B (fi) 1980-11-28
NO136459B (hu) 1977-05-31
GB1410505A (en) 1975-10-15
FR2157828A1 (hu) 1973-06-08
SE7509456L (sv) 1975-08-26
SE419984B (sv) 1981-09-07
RO67479A (ro) 1981-06-21
RO67478A (ro) 1980-03-15
BG21386A3 (hu) 1976-05-20
NO136459C (no) 1977-09-07
DE2248237C2 (de) 1983-02-10

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