DE2117571C3 - Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel - Google Patents

Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Info

Publication number
DE2117571C3
DE2117571C3 DE2117571A DE2117571A DE2117571C3 DE 2117571 C3 DE2117571 C3 DE 2117571C3 DE 2117571 A DE2117571 A DE 2117571A DE 2117571 A DE2117571 A DE 2117571A DE 2117571 C3 DE2117571 C3 DE 2117571C3
Authority
DE
Germany
Prior art keywords
ester
acid
dicarboxylic acid
ethyl
ethanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2117571A
Other languages
German (de)
English (en)
Other versions
DE2117571B2 (de
DE2117571A1 (de
Inventor
Friedrich Dr. Bossert
Horst Dr. Meyer
Kurt Dr. 5600 Wuppertal Stoepel
Wulf Dr. 5670 Opladen Vater
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5804433&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE2117571(C3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG filed Critical Bayer AG
Priority to DE2117571A priority Critical patent/DE2117571C3/de
Priority to CH346172A priority patent/CH567472A5/xx
Priority to AU40455/72A priority patent/AU464663B2/en
Priority to SU1768166A priority patent/SU435612A1/ru
Priority to BG020164A priority patent/BG22818A3/xx
Priority to FI946/72A priority patent/FI55186C/fi
Priority to ZA722348A priority patent/ZA722348B/xx
Priority to NL7204693.A priority patent/NL164031C/xx
Priority to DD168272*A priority patent/DD102077A5/xx
Priority to DK172372A priority patent/DK132496C/da
Priority to DD162147A priority patent/DD99371A5/xx
Priority to US00242239A priority patent/US3799934A/en
Priority to AT301672A priority patent/AT316551B/de
Priority to NO721190A priority patent/NO135589C/no
Priority to LU65138D priority patent/LU65138A1/xx
Priority to JP3450472A priority patent/JPS5529989B1/ja
Priority to IE454/72A priority patent/IE36265B1/xx
Priority to PL1972154622A priority patent/PL84499B1/pl
Priority to ES401614A priority patent/ES401614A1/es
Priority to RO197275177A priority patent/RO62643A/ro
Priority to IL7239171A priority patent/IL39171A/xx
Priority to CS2377A priority patent/CS175429B2/cs
Priority to YU96072A priority patent/YU34993B/xx
Priority to CA139295A priority patent/CA921035A/en
Priority to GB1646272A priority patent/GB1358951A/en
Priority to FR7212512A priority patent/FR2132830B1/fr
Priority to BE781878A priority patent/BE781878A/xx
Priority to RO197270487A priority patent/RO60479A/ro
Priority to SE7204606A priority patent/SE371823B/xx
Priority to YU95672A priority patent/YU34992B/xx
Priority to HUBA2729A priority patent/HU164705B/hu
Publication of DE2117571A1 publication Critical patent/DE2117571A1/de
Priority to US05/398,982 priority patent/US3932645A/en
Priority to HK188/77A priority patent/HK18877A/xx
Publication of DE2117571B2 publication Critical patent/DE2117571B2/de
Publication of DE2117571C3 publication Critical patent/DE2117571C3/de
Application granted granted Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Coloring (AREA)
DE2117571A 1971-04-10 1971-04-10 Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel Expired DE2117571C3 (de)

Priority Applications (33)

Application Number Priority Date Filing Date Title
DE2117571A DE2117571C3 (de) 1971-04-10 1971-04-10 Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
CH346172A CH567472A5 (https=) 1971-04-10 1972-03-09
AU40455/72A AU464663B2 (en) 1971-04-10 1972-03-27 Improvements in or relating to 1,4-dihydro pyridinedicarboxylic acid esters
SU1768166A SU435612A1 (ru) 1972-04-05 Способ получения несимметричных эфир08 1,4-дигидропиридиндикарбоновых кислот
BG020164A BG22818A3 (bg) 1971-04-10 1972-04-06 Метод за получаване на несиметрични 1,4-дихидропиридин дикарбоновокисели естери
FI946/72A FI55186C (fi) 1971-04-10 1972-04-06 Foerfarande foer framstaellning av terapeutiskt anvaendbara osymmetriska 1 4-dihydropyridinkarboxylsyraestrar
ZA722348A ZA722348B (en) 1971-04-10 1972-04-07 New esters,their production,and their medicinal use
NL7204693.A NL164031C (nl) 1971-04-10 1972-04-07 Werkwijze voor het bereiden van een farmaceutisch preparaat met een de coronairvaten verwijdende werking, en de door toepassing daarvan verkregen gevormde voortbrengselen, alsmede daarvoor geschikte 1,4-dihydropyridine 3,5-dicarbonzuuresters.
DD168272*A DD102077A5 (https=) 1971-04-10 1972-04-07
DK172372A DK132496C (da) 1971-04-10 1972-04-07 Analogifremgangsmade til fremstilling af usymmetriske 1,4-dihydropyridincarboxylsyreestere
DD162147A DD99371A5 (https=) 1971-04-10 1972-04-07
US00242239A US3799934A (en) 1971-04-10 1972-04-07 Unsymmetrical esters of 1,4-dihydropyridine 3,5-dicarboxylic acid
AT301672A AT316551B (de) 1971-04-10 1972-04-07 Verfahren zur Herstellung von neuen unsymmetrischen 1,4-Dihydropyridincarbonsäureestern
NO721190A NO135589C (https=) 1971-04-10 1972-04-07
LU65138D LU65138A1 (https=) 1971-04-10 1972-04-07
JP3450472A JPS5529989B1 (https=) 1971-04-10 1972-04-07
IE454/72A IE36265B1 (en) 1971-04-10 1972-04-07 New esters their production and their medicinal use
ES401614A ES401614A1 (es) 1971-04-10 1972-04-08 Procedimiento para la obtencion de 1,4-dihidro - piridin- carboxilatos asimetricos.
PL1972154622A PL84499B1 (https=) 1971-04-10 1972-04-08
YU96072A YU34993B (en) 1971-04-10 1972-04-10 Process for preparing novel non-symmetric 1,4-dihydropyridines
RO197270487A RO60479A (https=) 1971-04-10 1972-04-10
CS2377A CS175429B2 (https=) 1971-04-10 1972-04-10
YU95672A YU34992B (en) 1971-04-10 1972-04-10 Process for preparing non-symmetric 1,4-dihydrpyridines
CA139295A CA921035A (en) 1971-04-10 1972-04-10 Process for the preparation of unsymmetrical esters of 1,4-dihydropyridine 3,5-dicarboxylic acid
GB1646272A GB1358951A (en) 1971-04-10 1972-04-10 Esters their production and their medicinal use
FR7212512A FR2132830B1 (https=) 1971-04-10 1972-04-10
BE781878A BE781878A (fr) 1971-04-10 1972-04-10 Nouveaux esters dissymetriques d'acides 1,4-dihydropyridine-dicarboxyliques, leur procede de preparation et leur application comme medicament
SE7204606A SE371823B (https=) 1971-04-10 1972-04-10
RO197275177A RO62643A (fr) 1971-04-10 1972-04-10 Procedepour la preparation des esters dissymetriques d'acide 1,4-dihydropyridin-3,5-dicarboxyliques
IL7239171A IL39171A (en) 1971-04-10 1972-04-10 Asymmetrical esters of 1,4-dihydropyridine 3,5-dicarboxylic acid derivatives,their production and their medicinal use
HUBA2729A HU164705B (https=) 1971-04-10 1972-04-10
US05/398,982 US3932645A (en) 1971-04-10 1973-09-20 Pharmaceutical compositions containing unsymmetrical esters of 1,4-dihydropyridine 3,5-dicarboxylic acid
HK188/77A HK18877A (en) 1971-04-10 1977-04-20 New esters, their production, and their medicinal use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2117571A DE2117571C3 (de) 1971-04-10 1971-04-10 Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Publications (3)

Publication Number Publication Date
DE2117571A1 DE2117571A1 (de) 1972-10-19
DE2117571B2 DE2117571B2 (de) 1979-01-11
DE2117571C3 true DE2117571C3 (de) 1979-10-11

Family

ID=5804433

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2117571A Expired DE2117571C3 (de) 1971-04-10 1971-04-10 Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Country Status (27)

Country Link
US (1) US3799934A (https=)
JP (1) JPS5529989B1 (https=)
AT (1) AT316551B (https=)
AU (1) AU464663B2 (https=)
BE (1) BE781878A (https=)
BG (1) BG22818A3 (https=)
CA (1) CA921035A (https=)
CH (1) CH567472A5 (https=)
CS (1) CS175429B2 (https=)
DD (2) DD99371A5 (https=)
DE (1) DE2117571C3 (https=)
DK (1) DK132496C (https=)
ES (1) ES401614A1 (https=)
FI (1) FI55186C (https=)
FR (1) FR2132830B1 (https=)
GB (1) GB1358951A (https=)
HK (1) HK18877A (https=)
HU (1) HU164705B (https=)
IE (1) IE36265B1 (https=)
IL (1) IL39171A (https=)
LU (1) LU65138A1 (https=)
NL (1) NL164031C (https=)
NO (1) NO135589C (https=)
PL (1) PL84499B1 (https=)
RO (2) RO62643A (https=)
SE (1) SE371823B (https=)
ZA (1) ZA722348B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418207A (en) 1979-07-11 1983-11-29 Hoechst Aktiengesellschaft Acetylacetoxyalkyl-allyl ethers

Families Citing this family (102)

* Cited by examiner, † Cited by third party
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HK18877A (en) 1977-04-29
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