DE2100324A1 - Verfahren zur Herstellung von 21 Fluor steroiden - Google Patents

Verfahren zur Herstellung von 21 Fluor steroiden

Info

Publication number
DE2100324A1
DE2100324A1 DE19712100324 DE2100324A DE2100324A1 DE 2100324 A1 DE2100324 A1 DE 2100324A1 DE 19712100324 DE19712100324 DE 19712100324 DE 2100324 A DE2100324 A DE 2100324A DE 2100324 A1 DE2100324 A1 DE 2100324A1
Authority
DE
Germany
Prior art keywords
hydrogen
reaction
carried out
formula
diazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19712100324
Other languages
German (de)
English (en)
Inventor
Georg Dr Basel Wieland Peter Dr Oberwil Anner, (Schweiz)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of DE2100324A1 publication Critical patent/DE2100324A1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
DE19712100324 1970-01-09 1971-01-05 Verfahren zur Herstellung von 21 Fluor steroiden Pending DE2100324A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH24170A CH528496A (de) 1970-01-09 1970-01-09 Verfahren zur Herstellung von 21-Fluorsteroiden

Publications (1)

Publication Number Publication Date
DE2100324A1 true DE2100324A1 (de) 1971-07-15

Family

ID=4182500

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712100324 Pending DE2100324A1 (de) 1970-01-09 1971-01-05 Verfahren zur Herstellung von 21 Fluor steroiden

Country Status (14)

Country Link
US (1) US3758524A (enExample)
JP (1) JPS5037663B1 (enExample)
AT (1) AT309705B (enExample)
BE (1) BE761363A (enExample)
CA (1) CA984378A (enExample)
CH (2) CH528496A (enExample)
DE (1) DE2100324A1 (enExample)
DK (1) DK129836B (enExample)
ES (1) ES387060A1 (enExample)
FR (1) FR2081420B1 (enExample)
GB (1) GB1320301A (enExample)
NL (1) NL7100248A (enExample)
SE (1) SE368823B (enExample)
ZA (1) ZA708690B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996359A (en) * 1972-05-19 1976-12-07 Ab Bofors Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
US4361558A (en) * 1980-04-29 1982-11-30 Ciba-Geigy Corporation Halogenated steroids

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3207768A (en) * 1962-05-15 1965-09-21 Lepetit Spa Process for the manufacture of 16beta-methyl desoxycorticosterone and its 21-acetate
US3505317A (en) * 1966-12-29 1970-04-07 Merck & Co Inc 16-methylene-21-fluoro-steroids of the pregnane series

Also Published As

Publication number Publication date
NL7100248A (enExample) 1971-07-13
DK129836B (da) 1974-11-25
FR2081420A1 (enExample) 1971-12-03
CH530975A (de) 1972-11-30
BE761363A (fr) 1971-07-08
ZA708690B (en) 1971-10-27
CA984378A (en) 1976-02-24
DK129836C (enExample) 1975-04-28
ES387060A1 (es) 1973-05-01
GB1320301A (en) 1973-06-13
JPS5037663B1 (enExample) 1975-12-04
US3758524A (en) 1973-09-11
CH528496A (de) 1972-09-30
SE368823B (enExample) 1974-07-22
FR2081420B1 (enExample) 1974-09-20
AT309705B (de) 1973-08-27

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