GB1320301A - 21-fluorosteroids and their preparation - Google Patents
21-fluorosteroids and their preparationInfo
- Publication number
- GB1320301A GB1320301A GB103071A GB103071A GB1320301A GB 1320301 A GB1320301 A GB 1320301A GB 103071 A GB103071 A GB 103071A GB 103071 A GB103071 A GB 103071A GB 1320301 A GB1320301 A GB 1320301A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroids
- coch
- fluoro
- jan
- hydroxyl groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 C2U 21 - Fluoro - 20 - oxo - pregnane compounds Chemical class 0.000 abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 125000000664 diazo group Chemical group [N-]=[N+]=[*] 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 150000003431 steroids Chemical class 0.000 abstract 2
- FKCGMWXXOSUUQX-UHFFFAOYSA-N 2-diazo-2-nitroacetic acid Chemical class [N+](=O)([O-])C(C(=O)O)=[N+]=[N-] FKCGMWXXOSUUQX-UHFFFAOYSA-N 0.000 abstract 1
- PEHCVWCMOQNDGA-UHFFFAOYSA-N 2-diazonioimino-3-ethyl-1,3-benzothiazole Chemical compound C1=CC=C2[N+](CC)=C(N=[N+]=[N-])SC2=C1 PEHCVWCMOQNDGA-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH24170A CH528496A (de) | 1970-01-09 | 1970-01-09 | Verfahren zur Herstellung von 21-Fluorsteroiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1320301A true GB1320301A (en) | 1973-06-13 |
Family
ID=4182500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB103071A Expired GB1320301A (en) | 1970-01-09 | 1971-01-08 | 21-fluorosteroids and their preparation |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3758524A (enExample) |
| JP (1) | JPS5037663B1 (enExample) |
| AT (1) | AT309705B (enExample) |
| BE (1) | BE761363A (enExample) |
| CA (1) | CA984378A (enExample) |
| CH (2) | CH528496A (enExample) |
| DE (1) | DE2100324A1 (enExample) |
| DK (1) | DK129836B (enExample) |
| ES (1) | ES387060A1 (enExample) |
| FR (1) | FR2081420B1 (enExample) |
| GB (1) | GB1320301A (enExample) |
| NL (1) | NL7100248A (enExample) |
| SE (1) | SE368823B (enExample) |
| ZA (1) | ZA708690B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3996359A (en) * | 1972-05-19 | 1976-12-07 | Ab Bofors | Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith |
| US4361558A (en) * | 1980-04-29 | 1982-11-30 | Ciba-Geigy Corporation | Halogenated steroids |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3207768A (en) * | 1962-05-15 | 1965-09-21 | Lepetit Spa | Process for the manufacture of 16beta-methyl desoxycorticosterone and its 21-acetate |
| US3505317A (en) * | 1966-12-29 | 1970-04-07 | Merck & Co Inc | 16-methylene-21-fluoro-steroids of the pregnane series |
-
1970
- 1970-01-09 CH CH24170A patent/CH528496A/de not_active IP Right Cessation
- 1970-01-09 CH CH1081672A patent/CH530975A/de not_active IP Right Cessation
- 1970-12-23 CA CA101,369A patent/CA984378A/en not_active Expired
- 1970-12-28 ZA ZA708690A patent/ZA708690B/xx unknown
- 1970-12-30 FR FR7047182A patent/FR2081420B1/fr not_active Expired
- 1970-12-30 US US00103010A patent/US3758524A/en not_active Expired - Lifetime
- 1970-12-31 JP JP45123837A patent/JPS5037663B1/ja active Pending
-
1971
- 1971-01-05 DE DE19712100324 patent/DE2100324A1/de active Pending
- 1971-01-07 ES ES387060A patent/ES387060A1/es not_active Expired
- 1971-01-08 NL NL7100248A patent/NL7100248A/xx unknown
- 1971-01-08 SE SE00156/71A patent/SE368823B/xx unknown
- 1971-01-08 BE BE761363A patent/BE761363A/xx unknown
- 1971-01-08 DK DK7071AA patent/DK129836B/da unknown
- 1971-01-08 AT AT11571A patent/AT309705B/de not_active IP Right Cessation
- 1971-01-08 GB GB103071A patent/GB1320301A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE368823B (enExample) | 1974-07-22 |
| DK129836B (da) | 1974-11-25 |
| JPS5037663B1 (enExample) | 1975-12-04 |
| CA984378A (en) | 1976-02-24 |
| US3758524A (en) | 1973-09-11 |
| DE2100324A1 (de) | 1971-07-15 |
| CH528496A (de) | 1972-09-30 |
| AT309705B (de) | 1973-08-27 |
| FR2081420A1 (enExample) | 1971-12-03 |
| BE761363A (fr) | 1971-07-08 |
| FR2081420B1 (enExample) | 1974-09-20 |
| ZA708690B (en) | 1971-10-27 |
| DK129836C (enExample) | 1975-04-28 |
| ES387060A1 (es) | 1973-05-01 |
| NL7100248A (enExample) | 1971-07-13 |
| CH530975A (de) | 1972-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PLNP | Patent lapsed through nonpayment of renewal fees |