DE2009743A1 - Substituierte Biguanide mit antihyperglykämischer Wirkung - Google Patents

Substituierte Biguanide mit antihyperglykämischer Wirkung

Info

Publication number
DE2009743A1
DE2009743A1 DE19702009743 DE2009743A DE2009743A1 DE 2009743 A1 DE2009743 A1 DE 2009743A1 DE 19702009743 DE19702009743 DE 19702009743 DE 2009743 A DE2009743 A DE 2009743A DE 2009743 A1 DE2009743 A1 DE 2009743A1
Authority
DE
Germany
Prior art keywords
general formula
deep
compounds
carbon atoms
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19702009743
Other languages
German (de)
English (en)
Inventor
Hans-Joachim Dr.; Petersen Siegfried Prof.Dr.; 5090 Leverkusen; Horstmann Harald Dr.; Plumpe Hans Dr.; Puls Walter Dr.; 5600 Wuppertal-Elberfeld Kabbe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to DE19702009743 priority Critical patent/DE2009743A1/de
Priority to CH197171A priority patent/CH553756A/xx
Priority to CH1459473A priority patent/CH564526A5/xx
Priority to IL7136271A priority patent/IL36271A0/xx
Priority to IE227/71A priority patent/IE34966B1/xx
Priority to ZA711269A priority patent/ZA711269B/xx
Priority to NL7102612A priority patent/NL7102612A/xx
Priority to AT176071A priority patent/AT302350B/de
Priority to BE763725A priority patent/BE763725A/xx
Priority to ES388863A priority patent/ES388863A1/es
Priority to FR7107367A priority patent/FR2085665B1/fr
Priority to GB2281571A priority patent/GB1343831A/en
Priority to ES391629A priority patent/ES391629A1/es
Publication of DE2009743A1 publication Critical patent/DE2009743A1/de
Priority to US324218A priority patent/US3879541A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19702009743 1970-03-03 1970-03-03 Substituierte Biguanide mit antihyperglykämischer Wirkung Pending DE2009743A1 (de)

Priority Applications (14)

Application Number Priority Date Filing Date Title
DE19702009743 DE2009743A1 (de) 1970-03-03 1970-03-03 Substituierte Biguanide mit antihyperglykämischer Wirkung
CH197171A CH553756A (de) 1970-03-03 1971-02-10 Verfahren zur herstellung von biguaniden und deren verwendung.
CH1459473A CH564526A5 (cs) 1970-03-03 1971-02-10
IL7136271A IL36271A0 (en) 1970-03-03 1971-02-23 Substituted biguanides,their preparation and pharmaceutical compositions containing them
IE227/71A IE34966B1 (en) 1970-03-03 1971-02-23 The pharmaceutical use of certain substituted biguanides
ZA711269A ZA711269B (en) 1970-03-03 1971-02-26 New substituted biguanides and their pharmaceutical use
NL7102612A NL7102612A (cs) 1970-03-03 1971-02-26
AT176071A AT302350B (de) 1970-03-03 1971-03-02 Verfahren zur Herstellung von neuen substituierten Biguaniden und ihren Salzen
BE763725A BE763725A (cs) 1970-03-03 1971-03-03
ES388863A ES388863A1 (es) 1970-03-03 1971-03-03 Procedimiento para la obtencion de biguanidas.
FR7107367A FR2085665B1 (cs) 1970-03-03 1971-03-03
GB2281571A GB1343831A (en) 1970-03-03 1971-04-19 Pharmaceutical use of certain substituted biguanides
ES391629A ES391629A1 (es) 1970-03-03 1971-05-27 Procedimiento para la obtencion de biguanidas.
US324218A US3879541A (en) 1970-03-03 1973-01-16 Antihyperglycemic methods and compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702009743 DE2009743A1 (de) 1970-03-03 1970-03-03 Substituierte Biguanide mit antihyperglykämischer Wirkung

Publications (1)

Publication Number Publication Date
DE2009743A1 true DE2009743A1 (de) 1971-09-16

Family

ID=5763819

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19702009743 Pending DE2009743A1 (de) 1970-03-03 1970-03-03 Substituierte Biguanide mit antihyperglykämischer Wirkung

Country Status (11)

Country Link
AT (1) AT302350B (cs)
BE (1) BE763725A (cs)
CH (2) CH553756A (cs)
DE (1) DE2009743A1 (cs)
ES (2) ES388863A1 (cs)
FR (1) FR2085665B1 (cs)
GB (1) GB1343831A (cs)
IE (1) IE34966B1 (cs)
IL (1) IL36271A0 (cs)
NL (1) NL7102612A (cs)
ZA (1) ZA711269B (cs)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110615886A (zh) * 2019-09-05 2019-12-27 哈尔滨工程大学 一种双胍衍生物抗菌型环氧树脂固化剂及其制备方法

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2064664C (en) * 1991-04-05 2000-01-11 Hiroshi Ishikawa Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
DE19616486C5 (de) 1996-04-25 2016-06-30 Royalty Pharma Collection Trust Verfahren zur Senkung des Blutglukosespiegels in Säugern
DE19828114A1 (de) 1998-06-24 2000-01-27 Probiodrug Ges Fuer Arzneim Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
DE19828113A1 (de) 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
DE19834591A1 (de) 1998-07-31 2000-02-03 Probiodrug Ges Fuer Arzneim Verfahren zur Steigerung des Blutglukosespiegels in Säugern
DE19926233C1 (de) 1999-06-10 2000-10-19 Probiodrug Ges Fuer Arzneim Verfahren zur Herstellung von Thiazolidin
CN101690815A (zh) 2000-03-31 2010-04-07 普罗西迪恩有限公司 二肽基肽酶iv酶活性抑制剂的新用途
US7132104B1 (en) 2000-10-27 2006-11-07 Probiodrug Ag Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders
FR2822464B1 (fr) * 2001-03-21 2004-08-06 Lipha Derives biguanides et leurs applications en therapeutique
US6890905B2 (en) 2001-04-02 2005-05-10 Prosidion Limited Methods for improving islet signaling in diabetes mellitus and for its prevention
US20030130199A1 (en) 2001-06-27 2003-07-10 Von Hoersten Stephan Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
US7368421B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
DE10150203A1 (de) 2001-10-12 2003-04-17 Probiodrug Ag Peptidylketone als Inhibitoren der DPIV
US6844316B2 (en) 2001-09-06 2005-01-18 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
DK1480961T3 (da) 2002-02-28 2007-05-07 Prosidion Ltd Glutaminylbaserede DPIV-inhibitorer
JP2005522495A (ja) * 2002-04-11 2005-07-28 カルボマー インク 新規な糖尿病イメージングプローブ
KR20120035203A (ko) 2003-05-05 2012-04-13 프로비오드룩 아게 글루타미닐 및 글루타메이트 사이클라제의 이펙터의 용도
ATE462432T1 (de) 2003-05-05 2010-04-15 Probiodrug Ag Glutaminylcyclase-hemmer
WO2005075436A2 (en) 2004-02-05 2005-08-18 Probiodrug Ag Novel inhibitors of glutaminyl cyclase
CN115960018B (zh) * 2022-12-19 2024-01-05 湖南岳靶生物医药有限公司 一种egfr抑制剂、组合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR940304A (fr) * 1946-01-07 1948-12-09 Ici Ltd Procédé de fabrication de dérivés de biguanides
FR1053761A (fr) * 1949-01-31 1954-02-04 Ici Ltd Fabrication de dérivés de la biguanide
BE612641A (cs) * 1961-01-18
FR6786M (cs) * 1967-08-10 1969-03-17

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110615886A (zh) * 2019-09-05 2019-12-27 哈尔滨工程大学 一种双胍衍生物抗菌型环氧树脂固化剂及其制备方法

Also Published As

Publication number Publication date
FR2085665B1 (cs) 1974-08-30
IE34966L (en) 1971-09-03
AT302350B (de) 1972-10-10
ES388863A1 (es) 1973-06-01
IL36271A0 (en) 1971-04-28
FR2085665A1 (cs) 1971-12-31
CH553756A (de) 1974-09-13
CH564526A5 (cs) 1975-07-31
BE763725A (cs) 1971-09-03
GB1343831A (en) 1974-01-16
ES391629A1 (es) 1974-09-16
IE34966B1 (en) 1975-10-01
NL7102612A (cs) 1971-09-07
ZA711269B (en) 1971-11-24

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