ZA711269B - New substituted biguanides and their pharmaceutical use - Google Patents

New substituted biguanides and their pharmaceutical use

Info

Publication number
ZA711269B
ZA711269B ZA711269A ZA711269A ZA711269B ZA 711269 B ZA711269 B ZA 711269B ZA 711269 A ZA711269 A ZA 711269A ZA 711269 A ZA711269 A ZA 711269A ZA 711269 B ZA711269 B ZA 711269B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical use
new substituted
substituted biguanides
biguanides
new
Prior art date
Application number
ZA711269A
Inventor
S Petersin
H Pluempe
W Puls
H Kabbe
H Horstmann
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA711269B publication Critical patent/ZA711269B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA711269A 1970-03-03 1971-02-26 New substituted biguanides and their pharmaceutical use ZA711269B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702009743 DE2009743A1 (en) 1970-03-03 1970-03-03 Substituted biguanides with antihyperglycemic effects

Publications (1)

Publication Number Publication Date
ZA711269B true ZA711269B (en) 1971-11-24

Family

ID=5763819

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA711269A ZA711269B (en) 1970-03-03 1971-02-26 New substituted biguanides and their pharmaceutical use

Country Status (11)

Country Link
AT (1) AT302350B (en)
BE (1) BE763725A (en)
CH (2) CH564526A5 (en)
DE (1) DE2009743A1 (en)
ES (2) ES388863A1 (en)
FR (1) FR2085665B1 (en)
GB (1) GB1343831A (en)
IE (1) IE34966B1 (en)
IL (1) IL36271A0 (en)
NL (1) NL7102612A (en)
ZA (1) ZA711269B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2064664C (en) * 1991-04-05 2000-01-11 Hiroshi Ishikawa Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
DE19616486C5 (en) 1996-04-25 2016-06-30 Royalty Pharma Collection Trust Method for lowering the blood glucose level in mammals
DE19828114A1 (en) 1998-06-24 2000-01-27 Probiodrug Ges Fuer Arzneim Produgs of unstable inhibitors of dipeptidyl peptidase IV
DE19828113A1 (en) 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs of Dipeptidyl Peptidase IV Inhibitors
DE19834591A1 (en) 1998-07-31 2000-02-03 Probiodrug Ges Fuer Arzneim Use of substances that decrease the activity of dipeptidyl peptidase IV to increase blood sugar levels, e.g. for treating hypoglycemia
DE19926233C1 (en) 1999-06-10 2000-10-19 Probiodrug Ges Fuer Arzneim Production of thiazolidine, useful as pharmaceutical intermediate, comprises reacting hexamethylenetetramine with cysteamine
KR20080067009A (en) 2000-03-31 2008-07-17 프로시디온 리미티드 A pharmaceutical composition comprising dipeptidyl peptidase iv enzyme activity inhibitor
US7132104B1 (en) 2000-10-27 2006-11-07 Probiodrug Ag Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders
FR2822464B1 (en) 2001-03-21 2004-08-06 Lipha BIGUANIDE DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS
US6890905B2 (en) 2001-04-02 2005-05-10 Prosidion Limited Methods for improving islet signaling in diabetes mellitus and for its prevention
DE10150203A1 (en) 2001-10-12 2003-04-17 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitor in treatment of cancer
US20030130199A1 (en) 2001-06-27 2003-07-10 Von Hoersten Stephan Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
US7368421B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
US6844316B2 (en) 2001-09-06 2005-01-18 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
ES2278944T3 (en) 2002-02-28 2007-08-16 Prosidion Ltd. DPIV INHIBITORS BASED ON GLUTAMINYL.
WO2003086563A2 (en) * 2002-04-11 2003-10-23 Carbomer, Inc. Diabetes imaging probes
ZA200508439B (en) 2003-05-05 2007-03-28 Probiodrug Ag Medical use of inhibitors of glutaminyl and glutamate cyclases
DE202004021723U1 (en) 2003-05-05 2010-07-15 Probiodrug Ag Medical use of inhibitors of glutaminyl and glutamate cyclases
EP1713780B1 (en) 2004-02-05 2012-01-18 Probiodrug AG Novel inhibitors of glutaminyl cyclase
CN110615886A (en) * 2019-09-05 2019-12-27 哈尔滨工程大学 Biguanide derivative antibacterial epoxy resin curing agent and preparation method thereof
CN115960018B (en) * 2022-12-19 2024-01-05 湖南岳靶生物医药有限公司 EGFR inhibitor, composition and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR940304A (en) * 1946-01-07 1948-12-09 Ici Ltd Manufacturing process for biguanide derivatives
FR1053761A (en) * 1949-01-31 1954-02-04 Ici Ltd Manufacture of biguanide derivatives
NL273482A (en) * 1961-01-18
FR6786M (en) * 1967-08-10 1969-03-17

Also Published As

Publication number Publication date
AT302350B (en) 1972-10-10
CH553756A (en) 1974-09-13
CH564526A5 (en) 1975-07-31
FR2085665A1 (en) 1971-12-31
BE763725A (en) 1971-09-03
ES391629A1 (en) 1974-09-16
IE34966B1 (en) 1975-10-01
ES388863A1 (en) 1973-06-01
IE34966L (en) 1971-09-03
FR2085665B1 (en) 1974-08-30
GB1343831A (en) 1974-01-16
IL36271A0 (en) 1971-04-28
NL7102612A (en) 1971-09-07
DE2009743A1 (en) 1971-09-16

Similar Documents

Publication Publication Date Title
ZA71682B (en) New phenoxy-hydroxypropylamines and their preparation
EG10169A (en) New phenyl-imidazolyl-alkanyl derivatives their production and their pharmaceutical use
ZA711269B (en) New substituted biguanides and their pharmaceutical use
HK34379A (en) Tetrahydronaphthyloxyaminopropanols and related compounds
EG10637A (en) New aminophenylamidines,their production and their pharmaceutical use
ZA711030B (en) New n(6)-aralkyl-adenosine derivatives and the preparation thereof
IL36462A (en) 2-benzothiazolylurea derivatives and their use as herbicides
ZA714082B (en) New 2-amino-4-phenyl-thiazoles and their addition salts
PH9959A (en) 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes and salts thereof
ZA713877B (en) Pharmaceutical composition
ZA718104B (en) New n(6)-aralkyl-adenosine derivatives and the preparation thereof
IL37762A0 (en) New penicillins and their preparation
IL37563A0 (en) 8-cyano-5-octanolide and its preparation
ZA714539B (en) New 4-sulphamoyl-m-toluidine derivatives and the preparation thereof
ZA713371B (en) New penicillins,their preparation and their pharmaceutical use
ZA711607B (en) New n-vinyl-quinolones and the preparation thereof
IL37971A (en) 2-amino-4-thiocyanatobenzothiazoles and their preparation
ZA715815B (en) New cycloalkano-quinolone derivatives and the preparation thereof
ZA713906B (en) New nitrofuryl-amidine derivatives and the preparation thereof
IL36977A0 (en) 2,6-methano-3-benzazocines and their preparation
ZA711187B (en) Pharmaceutical use of certain substituted biguanides
IL37111A0 (en) New 2-aminoalkoxy-4-phenyl-thiazoles and their addition salts
ZA715706B (en) Herbicidally-active substituted phenyl-thiocarbamates and their manufacture and use
IL38281A (en) Substituted ypsilon-phenyl-butyronitriles and their preparation
IL36728A (en) Substituted pyrrolemethylamines and their preparation