AT302350B - Process for the production of new substituted biguanides and their salts - Google Patents
Process for the production of new substituted biguanides and their saltsInfo
- Publication number
- AT302350B AT302350B AT176071A AT176071A AT302350B AT 302350 B AT302350 B AT 302350B AT 176071 A AT176071 A AT 176071A AT 176071 A AT176071 A AT 176071A AT 302350 B AT302350 B AT 302350B
- Authority
- AT
- Austria
- Prior art keywords
- salts
- production
- new substituted
- substituted biguanides
- biguanides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19702009743 DE2009743A1 (en) | 1970-03-03 | 1970-03-03 | Substituted biguanides with antihyperglycemic effects |
Publications (1)
Publication Number | Publication Date |
---|---|
AT302350B true AT302350B (en) | 1972-10-10 |
Family
ID=5763819
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT176071A AT302350B (en) | 1970-03-03 | 1971-03-02 | Process for the production of new substituted biguanides and their salts |
Country Status (11)
Country | Link |
---|---|
AT (1) | AT302350B (en) |
BE (1) | BE763725A (en) |
CH (2) | CH553756A (en) |
DE (1) | DE2009743A1 (en) |
ES (2) | ES388863A1 (en) |
FR (1) | FR2085665B1 (en) |
GB (1) | GB1343831A (en) |
IE (1) | IE34966B1 (en) |
IL (1) | IL36271A0 (en) |
NL (1) | NL7102612A (en) |
ZA (1) | ZA711269B (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2064664C (en) * | 1991-04-05 | 2000-01-11 | Hiroshi Ishikawa | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives |
DE122010000020I1 (en) | 1996-04-25 | 2010-07-08 | Prosidion Ltd | Method for lowering the blood glucose level in mammals |
DE19828113A1 (en) | 1998-06-24 | 2000-01-05 | Probiodrug Ges Fuer Arzneim | Prodrugs of Dipeptidyl Peptidase IV Inhibitors |
DE19828114A1 (en) | 1998-06-24 | 2000-01-27 | Probiodrug Ges Fuer Arzneim | Produgs of unstable inhibitors of dipeptidyl peptidase IV |
DE19834591A1 (en) | 1998-07-31 | 2000-02-03 | Probiodrug Ges Fuer Arzneim | Use of substances that decrease the activity of dipeptidyl peptidase IV to increase blood sugar levels, e.g. for treating hypoglycemia |
DE19926233C1 (en) | 1999-06-10 | 2000-10-19 | Probiodrug Ges Fuer Arzneim | Production of thiazolidine, useful as pharmaceutical intermediate, comprises reacting hexamethylenetetramine with cysteamine |
CZ20023234A3 (en) | 2000-03-31 | 2003-01-15 | Probiodrug Ag | Medicament against diabetes mellitus |
US7132104B1 (en) | 2000-10-27 | 2006-11-07 | Probiodrug Ag | Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders |
FR2822464B1 (en) | 2001-03-21 | 2004-08-06 | Lipha | BIGUANIDE DERIVATIVES AND THEIR THERAPEUTIC APPLICATIONS |
US6890905B2 (en) | 2001-04-02 | 2005-05-10 | Prosidion Limited | Methods for improving islet signaling in diabetes mellitus and for its prevention |
DE10150203A1 (en) | 2001-10-12 | 2003-04-17 | Probiodrug Ag | Use of dipeptidyl peptidase IV inhibitor in treatment of cancer |
US7368421B2 (en) | 2001-06-27 | 2008-05-06 | Probiodrug Ag | Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis |
US20030130199A1 (en) | 2001-06-27 | 2003-07-10 | Von Hoersten Stephan | Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents |
US6844316B2 (en) | 2001-09-06 | 2005-01-18 | Probiodrug Ag | Inhibitors of dipeptidyl peptidase I |
PT1480961E (en) | 2002-02-28 | 2007-02-28 | Prosidion Ltd | Glutaminyl based dpiv inhibitors |
AU2003224917A1 (en) | 2002-04-11 | 2003-10-27 | Carbomer | Diabetes imaging probes |
US7371871B2 (en) | 2003-05-05 | 2008-05-13 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
KR20060009902A (en) | 2003-05-05 | 2006-02-01 | 프로비오드룩 아게 | Use of effectors of glutaminyl and glutamate cyclases |
JP4996926B2 (en) | 2004-02-05 | 2012-08-08 | プロビオドルグ エージー | Novel inhibitors of glutaminyl cyclase |
CN110615886A (en) * | 2019-09-05 | 2019-12-27 | 哈尔滨工程大学 | Biguanide derivative antibacterial epoxy resin curing agent and preparation method thereof |
CN115960018B (en) * | 2022-12-19 | 2024-01-05 | 湖南岳靶生物医药有限公司 | EGFR inhibitor, composition and application thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR940304A (en) * | 1946-01-07 | 1948-12-09 | Ici Ltd | Manufacturing process for biguanide derivatives |
FR1053761A (en) * | 1949-01-31 | 1954-02-04 | Ici Ltd | Manufacture of biguanide derivatives |
NL273482A (en) * | 1961-01-18 | |||
FR6786M (en) * | 1967-08-10 | 1969-03-17 |
-
1970
- 1970-03-03 DE DE19702009743 patent/DE2009743A1/en active Pending
-
1971
- 1971-02-10 CH CH197171A patent/CH553756A/en not_active IP Right Cessation
- 1971-02-10 CH CH1459473A patent/CH564526A5/xx not_active IP Right Cessation
- 1971-02-23 IE IE227/71A patent/IE34966B1/en unknown
- 1971-02-23 IL IL7136271A patent/IL36271A0/en unknown
- 1971-02-26 NL NL7102612A patent/NL7102612A/xx unknown
- 1971-02-26 ZA ZA711269A patent/ZA711269B/en unknown
- 1971-03-02 AT AT176071A patent/AT302350B/en not_active IP Right Cessation
- 1971-03-03 FR FR7107367A patent/FR2085665B1/fr not_active Expired
- 1971-03-03 BE BE763725A patent/BE763725A/xx unknown
- 1971-03-03 ES ES388863A patent/ES388863A1/en not_active Expired
- 1971-04-19 GB GB2281571A patent/GB1343831A/en not_active Expired
- 1971-05-27 ES ES391629A patent/ES391629A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
BE763725A (en) | 1971-09-03 |
CH553756A (en) | 1974-09-13 |
DE2009743A1 (en) | 1971-09-16 |
CH564526A5 (en) | 1975-07-31 |
FR2085665B1 (en) | 1974-08-30 |
FR2085665A1 (en) | 1971-12-31 |
NL7102612A (en) | 1971-09-07 |
IL36271A0 (en) | 1971-04-28 |
ZA711269B (en) | 1971-11-24 |
IE34966L (en) | 1971-09-03 |
IE34966B1 (en) | 1975-10-01 |
GB1343831A (en) | 1974-01-16 |
ES391629A1 (en) | 1974-09-16 |
ES388863A1 (en) | 1973-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELJ | Ceased due to non-payment of the annual fee |