DE2006514C3 - Ein Verfahren zur Herstellung von proteolytischen enzymatischen Produkten, die in vivo dem Schleim des Darmkanals, dem Bronchialschleim und dem Zervixschleim die optimale Viskosität verleihen und deren Verwendung als Zusatz in Nahrungs- und Futtermitteln - Google Patents
Ein Verfahren zur Herstellung von proteolytischen enzymatischen Produkten, die in vivo dem Schleim des Darmkanals, dem Bronchialschleim und dem Zervixschleim die optimale Viskosität verleihen und deren Verwendung als Zusatz in Nahrungs- und FuttermittelnInfo
- Publication number
- DE2006514C3 DE2006514C3 DE2006514A DE2006514A DE2006514C3 DE 2006514 C3 DE2006514 C3 DE 2006514C3 DE 2006514 A DE2006514 A DE 2006514A DE 2006514 A DE2006514 A DE 2006514A DE 2006514 C3 DE2006514 C3 DE 2006514C3
- Authority
- DE
- Germany
- Prior art keywords
- mucus
- viscosity
- feed
- trypsin
- units
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000003097 mucus Anatomy 0.000 title claims description 49
- 230000002255 enzymatic effect Effects 0.000 title claims description 24
- 230000000968 intestinal effect Effects 0.000 title claims description 21
- 235000013305 food Nutrition 0.000 title claims description 14
- 238000000034 method Methods 0.000 title claims description 11
- 238000001727 in vivo Methods 0.000 title claims description 8
- 230000002797 proteolythic effect Effects 0.000 title claims description 6
- 239000000654 additive Substances 0.000 title claims description 3
- 230000000996 additive effect Effects 0.000 title claims 2
- 210000003756 cervix mucus Anatomy 0.000 title claims 2
- 238000004519 manufacturing process Methods 0.000 title description 4
- 230000000694 effects Effects 0.000 claims description 20
- 238000002360 preparation method Methods 0.000 claims description 20
- 108090000317 Chymotrypsin Proteins 0.000 claims description 15
- 108090000631 Trypsin Proteins 0.000 claims description 15
- 102000004142 Trypsin Human genes 0.000 claims description 15
- 229960002376 chymotrypsin Drugs 0.000 claims description 15
- 230000007423 decrease Effects 0.000 claims description 14
- 238000000855 fermentation Methods 0.000 claims description 14
- 230000004151 fermentation Effects 0.000 claims description 14
- 230000009467 reduction Effects 0.000 claims description 14
- 239000012588 trypsin Substances 0.000 claims description 14
- 241000187438 Streptomyces fradiae Species 0.000 claims description 11
- 239000002753 trypsin inhibitor Substances 0.000 claims description 9
- 102000035195 Peptidases Human genes 0.000 claims description 8
- 108091005804 Peptidases Proteins 0.000 claims description 8
- 239000000243 solution Substances 0.000 claims description 8
- 244000005700 microbiome Species 0.000 claims description 7
- 244000309466 calf Species 0.000 claims description 6
- 238000000338 in vitro Methods 0.000 claims description 5
- 230000007515 enzymatic degradation Effects 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims description 3
- 241000187747 Streptomyces Species 0.000 claims description 2
- 239000008366 buffered solution Substances 0.000 claims description 2
- 102000004190 Enzymes Human genes 0.000 description 62
- 108090000790 Enzymes Proteins 0.000 description 62
- 229940088598 enzyme Drugs 0.000 description 62
- 239000000047 product Substances 0.000 description 43
- 238000012360 testing method Methods 0.000 description 38
- 238000002474 experimental method Methods 0.000 description 37
- 241001465754 Metazoa Species 0.000 description 23
- 241000700159 Rattus Species 0.000 description 19
- 241000287828 Gallus gallus Species 0.000 description 11
- 235000013330 chicken meat Nutrition 0.000 description 11
- 235000015097 nutrients Nutrition 0.000 description 10
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 8
- 238000010521 absorption reaction Methods 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- 235000018102 proteins Nutrition 0.000 description 7
- 102000004169 proteins and genes Human genes 0.000 description 7
- 235000020188 drinking water Nutrition 0.000 description 6
- 239000003651 drinking water Substances 0.000 description 6
- 108090000623 proteins and genes Proteins 0.000 description 6
- 239000003112 inhibitor Substances 0.000 description 5
- 235000010469 Glycine max Nutrition 0.000 description 4
- 239000004365 Protease Substances 0.000 description 4
- 240000008042 Zea mays Species 0.000 description 4
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 4
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 4
- 235000005822 corn Nutrition 0.000 description 4
- 230000029087 digestion Effects 0.000 description 4
- 230000002496 gastric effect Effects 0.000 description 4
- 210000000936 intestine Anatomy 0.000 description 4
- 210000004400 mucous membrane Anatomy 0.000 description 4
- 229910052757 nitrogen Inorganic materials 0.000 description 4
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 description 4
- 244000063299 Bacillus subtilis Species 0.000 description 3
- 235000014469 Bacillus subtilis Nutrition 0.000 description 3
- 108090000526 Papain Proteins 0.000 description 3
- 235000019764 Soybean Meal Nutrition 0.000 description 3
- 108010073771 Soybean Proteins Proteins 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 238000009395 breeding Methods 0.000 description 3
- 230000001488 breeding effect Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 235000013312 flour Nutrition 0.000 description 3
- 210000003405 ileum Anatomy 0.000 description 3
- 150000002632 lipids Chemical class 0.000 description 3
- 229940055729 papain Drugs 0.000 description 3
- 235000019834 papain Nutrition 0.000 description 3
- 238000001556 precipitation Methods 0.000 description 3
- 239000000523 sample Substances 0.000 description 3
- 229940001941 soy protein Drugs 0.000 description 3
- 239000004455 soybean meal Substances 0.000 description 3
- 235000019786 weight gain Nutrition 0.000 description 3
- 230000004584 weight gain Effects 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 2
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 2
- 235000011130 ammonium sulphate Nutrition 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 235000021052 average daily weight gain Nutrition 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 239000005018 casein Substances 0.000 description 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 2
- 235000021240 caseins Nutrition 0.000 description 2
- 229940079919 digestives enzyme preparation Drugs 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 210000004907 gland Anatomy 0.000 description 2
- 239000001963 growth medium Substances 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 235000019833 protease Nutrition 0.000 description 2
- 210000002374 sebum Anatomy 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 1
- 102000015728 Mucins Human genes 0.000 description 1
- 108010063954 Mucins Proteins 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 239000004098 Tetracycline Substances 0.000 description 1
- 101710162629 Trypsin inhibitor Proteins 0.000 description 1
- 229940122618 Trypsin inhibitor Drugs 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 206010000210 abortion Diseases 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000001166 ammonium sulphate Substances 0.000 description 1
- 230000003625 amylolytic effect Effects 0.000 description 1
- 230000001195 anabolic effect Effects 0.000 description 1
- 235000019728 animal nutrition Nutrition 0.000 description 1
- 235000021120 animal protein Nutrition 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 238000011888 autopsy Methods 0.000 description 1
- 235000021053 average weight gain Nutrition 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 238000012364 cultivation method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 1
- 229910000396 dipotassium phosphate Inorganic materials 0.000 description 1
- 235000019797 dipotassium phosphate Nutrition 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000001962 electrophoresis Methods 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000000622 irritating effect Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 150000002605 large molecules Chemical class 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 235000021190 leftovers Nutrition 0.000 description 1
- 230000002366 lipolytic effect Effects 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 229940051875 mucins Drugs 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- LWIHDJKSTIGBAC-UHFFFAOYSA-K potassium phosphate Substances [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 description 1
- 229960004919 procaine Drugs 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 230000000384 rearing effect Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 239000012487 rinsing solution Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000003307 slaughter Methods 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000003760 tallow Substances 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Husbandry (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fodder In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB961969 | 1969-02-21 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DE2006514A1 DE2006514A1 (de) | 1970-09-10 |
| DE2006514B2 DE2006514B2 (de) | 1977-09-29 |
| DE2006514C3 true DE2006514C3 (de) | 1978-05-24 |
Family
ID=9875487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2006514A Expired DE2006514C3 (de) | 1969-02-21 | 1970-02-13 | Ein Verfahren zur Herstellung von proteolytischen enzymatischen Produkten, die in vivo dem Schleim des Darmkanals, dem Bronchialschleim und dem Zervixschleim die optimale Viskosität verleihen und deren Verwendung als Zusatz in Nahrungs- und Futtermitteln |
Country Status (17)
| Country | Link |
|---|---|
| AT (1) | AT297635B (en:Method) |
| BE (1) | BE745697A (en:Method) |
| CH (1) | CH513978A (en:Method) |
| CS (1) | CS151008B2 (en:Method) |
| DE (1) | DE2006514C3 (en:Method) |
| DK (1) | DK132666C (en:Method) |
| ES (1) | ES376787A1 (en:Method) |
| FR (1) | FR2034559B1 (en:Method) |
| GB (1) | GB1307516A (en:Method) |
| IE (1) | IE33729B1 (en:Method) |
| IL (1) | IL33904A (en:Method) |
| LU (1) | LU60376A1 (en:Method) |
| NL (1) | NL170965C (en:Method) |
| OA (1) | OA03218A (en:Method) |
| RO (1) | RO58428A2 (en:Method) |
| SE (1) | SE374389B (en:Method) |
| YU (1) | YU35032B (en:Method) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2600340A1 (fr) * | 1986-06-20 | 1987-12-24 | Hooremam Michel | Procede de production d'un nouveau complexe proteolytique stimulant l'activite du pancreas et ses applications en zootechnie |
| KR100563523B1 (ko) * | 1996-04-05 | 2006-07-06 | 미켈 호레만 | 점액점도를최적화시키고,장의기능을자극하기위한약제 |
| FR2747045B1 (fr) * | 1996-04-05 | 1998-06-26 | Hooreman Michel | Nouveau medicament optimisant la viscosite des mucus et ameliorant le fonctionnement de l'intestin |
| DE19724458A1 (de) * | 1997-06-10 | 1998-12-24 | Mucos Pharma Gmbh & Co | Verwendung proteolytischer Enzyme zur Verbesserung der Absorption von Arzneimitteln |
| FR2998450A1 (fr) * | 2012-11-26 | 2014-05-30 | Dominique Hooreman | Utilisation d'un complexe enzymatique dans l'alimentation des animaux d'elevage |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1133579A (en) * | 1966-03-09 | 1968-11-13 | Shionogi & Co | Process for preparing proteases and enzymatic composition prepared thereby |
-
1969
- 1969-02-21 RO RO62521A patent/RO58428A2/ro unknown
- 1969-02-21 GB GB961969A patent/GB1307516A/en not_active Expired
-
1970
- 1970-02-06 FR FR7004271A patent/FR2034559B1/fr not_active Expired
- 1970-02-06 CH CH171570A patent/CH513978A/fr not_active IP Right Cessation
- 1970-02-09 BE BE745697D patent/BE745697A/xx not_active IP Right Cessation
- 1970-02-13 DE DE2006514A patent/DE2006514C3/de not_active Expired
- 1970-02-16 IL IL33904A patent/IL33904A/xx unknown
- 1970-02-17 IE IE203/70A patent/IE33729B1/xx unknown
- 1970-02-18 AT AT147470A patent/AT297635B/de not_active IP Right Cessation
- 1970-02-18 OA OA53851A patent/OA03218A/xx unknown
- 1970-02-19 LU LU60376D patent/LU60376A1/xx unknown
- 1970-02-20 SE SE7002219A patent/SE374389B/xx unknown
- 1970-02-20 DK DK83670*#A patent/DK132666C/da active
- 1970-02-20 NL NLAANVRAGE7002466,A patent/NL170965C/xx active
- 1970-02-20 YU YU422/70A patent/YU35032B/xx unknown
- 1970-02-21 ES ES376787A patent/ES376787A1/es not_active Expired
- 1970-02-23 CS CS1213A patent/CS151008B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2034559B1 (en:Method) | 1974-03-22 |
| ES376787A1 (es) | 1972-05-01 |
| NL170965B (nl) | 1982-08-16 |
| FR2034559A1 (en:Method) | 1970-12-11 |
| OA03218A (fr) | 1970-12-15 |
| CH513978A (fr) | 1971-10-15 |
| NL7002466A (en:Method) | 1970-08-25 |
| DK132666B (da) | 1976-01-19 |
| SE374389B (en:Method) | 1975-03-03 |
| IE33729L (en) | 1970-08-21 |
| LU60376A1 (en:Method) | 1970-04-22 |
| DE2006514A1 (de) | 1970-09-10 |
| GB1307516A (en) | 1973-02-21 |
| IE33729B1 (en) | 1974-10-16 |
| IL33904A0 (en) | 1970-04-20 |
| BE745697A (fr) | 1970-07-16 |
| RO58428A2 (ro) | 1975-06-25 |
| NL170965C (nl) | 1983-01-17 |
| YU42270A (en) | 1979-12-31 |
| AT297635B (de) | 1972-04-10 |
| CS151008B2 (en:Method) | 1973-09-17 |
| IL33904A (en) | 1974-03-14 |
| YU35032B (en) | 1980-06-30 |
| DK132666C (da) | 1976-06-14 |
| DE2006514B2 (de) | 1977-09-29 |
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