DE19612967A1 - Verfahren zur Vermehrung von Influenzaviren in Zellkultur, sowie die durch das Verfahren erhältlichen Influenzaviren - Google Patents

Verfahren zur Vermehrung von Influenzaviren in Zellkultur, sowie die durch das Verfahren erhältlichen Influenzaviren

Info

Publication number
DE19612967A1
DE19612967A1 DE19612967A DE19612967A DE19612967A1 DE 19612967 A1 DE19612967 A1 DE 19612967A1 DE 19612967 A DE19612967 A DE 19612967A DE 19612967 A DE19612967 A DE 19612967A DE 19612967 A1 DE19612967 A1 DE 19612967A1
Authority
DE
Germany
Prior art keywords
cells
influenza viruses
influenza
virus
viruses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19612967A
Other languages
German (de)
English (en)
Inventor
Albrecht Dr Groener
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GSK Vaccines GmbH
Original Assignee
Behringwerke AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7790127&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE19612967(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Behringwerke AG filed Critical Behringwerke AG
Priority to DE19612967A priority Critical patent/DE19612967A1/de
Priority to EP97915628.8A priority patent/EP0891420B2/en
Priority to DE69732407.9T priority patent/DE69732407T3/de
Priority to ES09011476T priority patent/ES2435726T3/es
Priority to EP09011476.0A priority patent/EP2172543B1/en
Priority to ES05075182T priority patent/ES2367081T3/es
Priority to DK97915628.8T priority patent/DK0891420T4/da
Priority to DE122007000082C priority patent/DE122007000082I1/de
Priority to AT05075182T priority patent/ATE513905T1/de
Priority to CA002250078A priority patent/CA2250078C/en
Priority to DK05075182.5T priority patent/DK1526172T3/da
Priority to ES97915628T priority patent/ES2236799T5/es
Priority to PCT/IB1997/000404 priority patent/WO1997037001A1/en
Priority to PT97915628T priority patent/PT891420E/pt
Priority to JP53509097A priority patent/JP4447054B2/ja
Priority to EP05075182A priority patent/EP1526172B1/en
Priority to PT05075182T priority patent/PT1526172E/pt
Priority to AT97915628T priority patent/ATE288479T1/de
Publication of DE19612967A1 publication Critical patent/DE19612967A1/de
Priority to US10/245,037 priority patent/US20030119183A1/en
Priority to HK05109564.2A priority patent/HK1075467B/en
Priority to JP2006189769A priority patent/JP2006296437A/ja
Priority to US11/592,336 priority patent/US20070117131A1/en
Priority to NL300307C priority patent/NL300307I1/nl
Priority to LU91381C priority patent/LU91381I2/fr
Priority to JP2008169656A priority patent/JP2008245659A/ja
Priority to JP2010198362A priority patent/JP5264843B2/ja
Priority to HK10108428.3A priority patent/HK1142093B/en
Priority to JP2011157202A priority patent/JP2011212020A/ja
Priority to JP2013039239A priority patent/JP2013116124A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16151—Methods of production or purification of viral material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE19612967A 1996-04-01 1996-04-01 Verfahren zur Vermehrung von Influenzaviren in Zellkultur, sowie die durch das Verfahren erhältlichen Influenzaviren Withdrawn DE19612967A1 (de)

Priority Applications (29)

Application Number Priority Date Filing Date Title
DE19612967A DE19612967A1 (de) 1996-04-01 1996-04-01 Verfahren zur Vermehrung von Influenzaviren in Zellkultur, sowie die durch das Verfahren erhältlichen Influenzaviren
PT05075182T PT1526172E (pt) 1996-04-01 1997-04-01 Processo para a replicação de vírus influenza em cultura celular e os vírus influenza que podem ser obtidos pelo processo
JP53509097A JP4447054B2 (ja) 1996-04-01 1997-04-01 細胞培養におけるインフルエンザウイルスの複製の方法、および本方法によって入手可能なインフルエンザウイルス
EP05075182A EP1526172B1 (en) 1996-04-01 1997-04-01 Process for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process
ES09011476T ES2435726T3 (es) 1996-04-01 1997-04-01 Procedimiento para la replicación de virus de la gripe en cultivo celular y los virus de la gripe que pueden obtenerse por el procedimiento
EP09011476.0A EP2172543B1 (en) 1996-04-01 1997-04-01 Process for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process
ES05075182T ES2367081T3 (es) 1996-04-01 1997-04-01 Procedimiento para la replicación de virus de la gripe en cultivo celular y los virus de la gripe que pueden obtenerse por el procedimiento.
DK97915628.8T DK0891420T4 (da) 1996-04-01 1997-04-01 Fremgangsmåde til replikation af influenzavirus i cellekultur samt de ved fremgangsmåden opnåelige influenzavirus
DE122007000082C DE122007000082I1 (de) 1996-04-01 1997-04-01 Verfahren für die replikation von influenza in zellkultur und die bei diesem verfahren hergestellten influenza-viren
AT05075182T ATE513905T1 (de) 1996-04-01 1997-04-01 Verfahren für die replikation von influenza in zellkultur, und die bei diesem verfahren hergestellten influenza viren
CA002250078A CA2250078C (en) 1996-04-01 1997-04-01 Processes for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process
DE69732407.9T DE69732407T3 (de) 1996-04-01 1997-04-01 Verfahren für die Replikation von Influenza in Zellkultur und die bei diesem Verfahren hergestellten Influenza-Viren
ES97915628T ES2236799T5 (es) 1996-04-01 1997-04-01 Procedimientos de replicación de virus de influenza en cultivo celular y virus de influenza obtenibles por el procedimiento
PCT/IB1997/000404 WO1997037001A1 (en) 1996-04-01 1997-04-01 Processes for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process
PT97915628T PT891420E (pt) 1996-04-01 1997-04-01 Processos para a replicacao dos virus influenza numa cultura celular e os virus influenza que se podem obter atraves do processo
EP97915628.8A EP0891420B2 (en) 1996-04-01 1997-04-01 Processes for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process
AT97915628T ATE288479T1 (de) 1996-04-01 1997-04-01 Verfahren fuer die replikation von influenza in zellkultur und die bei diesem verfahren hergestellten influenza-viren
DK05075182.5T DK1526172T3 (da) 1996-04-01 1997-04-01 Fremgangsmåde til replikation af influenzavira i cellekultur og ved fremgangsmåden opnåelige influenzavira
US10/245,037 US20030119183A1 (en) 1996-04-01 2002-09-16 Processes for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process
HK05109564.2A HK1075467B (en) 1996-04-01 2005-10-27 Process for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process
JP2006189769A JP2006296437A (ja) 1996-04-01 2006-07-10 細胞培養におけるインフルエンザウイルスの複製の方法、および本方法によって入手可能なインフルエンザウイルス
US11/592,336 US20070117131A1 (en) 1996-04-01 2006-11-03 Processes for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process
NL300307C NL300307I1 (nl) 1996-04-01 2007-11-28 Werkwijzen voor de replicatie van influenzavirussen in celkweek en de influenzavirussen die verkrijgbaar zijn met behulp van de werkwijze
LU91381C LU91381I2 (fr) 1996-04-01 2007-11-30 OPTAFLU-Définition du produit: Vaccin grippal préparé à partir du virus de la grippe dans une culture celluluaire ou les cellules sont cultivées à unetempérature comprise entre 30°C et 36°C pour la r éplication des virus
JP2008169656A JP2008245659A (ja) 1996-04-01 2008-06-27 細胞培養におけるインフルエンザウイルスの複製の方法、および本方法によって入手可能なインフルエンザウイルス
JP2010198362A JP5264843B2 (ja) 1996-04-01 2010-09-03 細胞培養におけるインフルエンザウイルスの複製の方法、および本方法によって入手可能なインフルエンザウイルス
HK10108428.3A HK1142093B (en) 1996-04-01 2010-09-06 Process for the replication of influenza viruses in cell culture, and the influenza viruses obtainable by the process
JP2011157202A JP2011212020A (ja) 1996-04-01 2011-07-15 細胞培養におけるインフルエンザウイルスの複製の方法、および本方法によって入手可能なインフルエンザウイルス
JP2013039239A JP2013116124A (ja) 1996-04-01 2013-02-28 細胞培養におけるインフルエンザウイルスの複製の方法、および本方法によって入手可能なインフルエンザウイルス

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19612967A DE19612967A1 (de) 1996-04-01 1996-04-01 Verfahren zur Vermehrung von Influenzaviren in Zellkultur, sowie die durch das Verfahren erhältlichen Influenzaviren

Publications (1)

Publication Number Publication Date
DE19612967A1 true DE19612967A1 (de) 1997-10-02

Family

ID=7790127

Family Applications (3)

Application Number Title Priority Date Filing Date
DE19612967A Withdrawn DE19612967A1 (de) 1996-04-01 1996-04-01 Verfahren zur Vermehrung von Influenzaviren in Zellkultur, sowie die durch das Verfahren erhältlichen Influenzaviren
DE122007000082C Pending DE122007000082I1 (de) 1996-04-01 1997-04-01 Verfahren für die replikation von influenza in zellkultur und die bei diesem verfahren hergestellten influenza-viren
DE69732407.9T Expired - Lifetime DE69732407T3 (de) 1996-04-01 1997-04-01 Verfahren für die Replikation von Influenza in Zellkultur und die bei diesem Verfahren hergestellten Influenza-Viren

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE122007000082C Pending DE122007000082I1 (de) 1996-04-01 1997-04-01 Verfahren für die replikation von influenza in zellkultur und die bei diesem verfahren hergestellten influenza-viren
DE69732407.9T Expired - Lifetime DE69732407T3 (de) 1996-04-01 1997-04-01 Verfahren für die Replikation von Influenza in Zellkultur und die bei diesem Verfahren hergestellten Influenza-Viren

Country Status (12)

Country Link
US (2) US20030119183A1 (enExample)
EP (3) EP1526172B1 (enExample)
JP (6) JP4447054B2 (enExample)
AT (2) ATE288479T1 (enExample)
CA (1) CA2250078C (enExample)
DE (3) DE19612967A1 (enExample)
DK (2) DK1526172T3 (enExample)
ES (3) ES2435726T3 (enExample)
LU (1) LU91381I2 (enExample)
NL (1) NL300307I1 (enExample)
PT (2) PT891420E (enExample)
WO (1) WO1997037001A1 (enExample)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
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