DE19549520C9 - Ein flexibler ausdehnbarer Stent - Google Patents
Ein flexibler ausdehnbarer Stent Download PDFInfo
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- DE19549520C9 DE19549520C9 DE19549520A DE19549520A DE19549520C9 DE 19549520 C9 DE19549520 C9 DE 19549520C9 DE 19549520 A DE19549520 A DE 19549520A DE 19549520 A DE19549520 A DE 19549520A DE 19549520 C9 DE19549520 C9 DE 19549520C9
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/856—Single tubular stent with a side portal passage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
- A61F2002/91541—Adjacent bands are arranged out of phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
- A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0004—Rounded shapes, e.g. with rounded corners
- A61F2230/0013—Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0054—V-shaped
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Dowels (AREA)
- Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)
- Springs (AREA)
- Cable Accessories (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Rigid Pipes And Flexible Pipes (AREA)
Abstract
a) ein oder mehrere ungerade und ein oder mehrere gerade sich abwechselnde Serpentinenabschnitte (11o, 11e), von denen jeder erste Biegungsbereiche (14, 16) aufweist, wobei der ungerade Serpentinenabschnitt (11o) außer Phase mit dem geraden Serpentinenabschnitt (11e) derart ist, dass erste Biegungsbereiche (14, 16) an dem ungeraden Serpentinenabschnitt (11o) benachbart zu ersten Biegungsbereichen (16, 14) an dem geraden Serpentinenabschnitt (11e) sind; und
b) zumindest einen flexiblen Verbinder, welcher eine Vielzahl von in Längsrichtung des Stents dehnbaren Verbindungsgliedern in Form von Schlaufen (18, 20) eine Mäandermusters (12) aufweist, welche benachbarte erste Biegungsbereiche (14, 16) der benachbarten geraden und ungeraden Serpentinenabschnitten (11e, 11o) verbinden, wobei jedes flexible Verbindungsglied zumindest zwei Abschnitte (22) aufweist, welche durch zumindest einen zweiten Biegungsbereich (18, 20) verbunden sind, und wobei...
Description
- Die vorliegende Erfindung bezieht sich im allgemeinen auf Stents zum, Implantieren in einen lebenden Körper.
- Vielfältige Stents sind im Stand der Technik bekannt, bei welchen bezüglich der vorliegenden Erfindung der Begriff "Stent" eine Vorrichtung kennzeichnet, welche aus einem körper-kompatiblen Material besteht, welches zum Aufweiten eines Blutgefäßes oder einer anderen Öffnung in dem Körper und zum Aufrechterhalten der resultierenden Größe des Lumens verwendet wird. Typischerweise wird der Stent an den gewünschten Ort in dem Körper mittels eines aufblasbaren Ballons zugeführt, und, wenn der Ballon aufgeblasen wird, dehnt sich der Stent aus, wodurch sich die Öffnung erweitert. Andere mechanische Vorrichtungen, welche eine Ausdehnung des Stents bewirken, werden ebenfalls angewendet.
- Beispielhafte Patente auf dem Gebiet der Stents, welche aus Draht gebildet sind, sind:
US 5,019,090 von Punchuk,US 5,161,547 von Tower,US 4,950,227 von Savin et al,US 5,314,472 von Fontaine,US 4,886,062 undUS 4,969,458 von Wiktor undUS 4,856,516 von Hillstead. Stents, welche aus geschnittenem handelsüblichen Metall gebildet sind, sind beschrieben in:US 4,733,665 von Palmaz,US 4,762,128 von Rosenbluth,US 5,102,417 von Palmaz und Schatz,US 5,195,984 von Schatz undFR 2683449 A1 - Die in
US 5,102,417 von Palmaz und Schatz beschriebenen Stents stellen ausdehnbare röhrenförmige Implantate dar, welche mittels eines flexiblen Verbinders miteinander verbunden sind. Die Implantate sind aus einer Vielzahl von Schlitzen gebildet, welche parallel zur Längsachse der Röhre angeordnet sind. Die flexiblen Verbinder sind schraubenförmige Verbinderen. Da die röhrenförmigen Implantate relativ steif sind, werden die flexiblen Verbinder benötigt, so daß die Stents sich biegen können, wenn sie durch ein gekrümmtes Blutgefäß hindurchgeführt werden. Wenn die Stents gemäßUS 5,102,417 sich ausdehnen, dehnen sich die Implantate radial aus und schrumpfen folglich in Längsrichtung. Gleichzeitig verdrehen sich jedoch die schraubenförmigen Verbinder. Die Verdrehbewegung ist höchstwahrscheinlich für das Blutgefäß schädlich. -
US 5,195,984 von Schatz beschreibt einen ähnlichen Stent, jedoch mit einem geraden Verbinder, parallel zur Längsachse der röhrenförmigen Implantate, zwischen den röhrenförmigen Implantaten. Das gerade Element beseitigt die Verdrehbewegung; es ist jedoch kein sehr fester Verbinder. -
EP 0 540 290 A2 von Lau et al beschreibt einen Stent mit einer Vielzahl von radial ausdehnbaren zylindrischen Elementen, die aus bandartigem Material in gewelltem Muster bestehen, auf einer gemeinsamen Achse ausgerichtet und durch ein oder mehrere gerade Verbindungsstege miteinander verbunden sind. -
US 4,994,071 von MacGregor beschreibt einen gabelförmigen Stent mit einer Vielzahl von radial ausdehnbaren zylindrischen Elementen aus gewelltem Draht, die auf einer gemeinsamen Achse ausgerichtet und untereinander durch jeweils mindestens einen geraden Drahtabschnitt mit einem Knoten mit halbem Schlag verbunden sind. - Es ist deshalb ein Ziel der vorliegenden Erfindung, einen flexiblen Stent bereitzustellen, welcher während der Ausdehnung minimal in der Längsrichtung schrumpft.
- Dieses Ziel wird gemäß der vorliegenden Erfindung durch einen Stent gemäß Anspruch 1 oder 2 erreicht. Vorteilhafte Ausgestaltungen des erfindungsgemäßen Stents sind in den Unteransprüchen 3 bis 5 angeführt.
- Die vorliegende Erfindung wird aus der nachfolgenden detaillierten Beschreibung in Zusammenhang mit den Zeichnungen besser verständlich, in welchen:
-
1 eine Veranschaulichung eines gemusterten Stents, welcher gemäß einem ersten bevorzugten Ausführungsbeispiel der vorliegenden Erfindung aufgebaut und betriebsfähig ist; -
2 eine Veranschaulichung des Musters des Stents gemäß1 ist; -
3 eine Veranschaulichung des Stents gemäß1 in einer gebogenen Stellung ist; -
4 eine Veranschaulichung des Stents gemäß1 in einem ausgedehnten Format ist; -
5A und5B Veranschaulichungen der Änderungen in den Mustern des Stents gemäß1 infolge Ausdehnung sind; -
6 eine schematische Veranschaulichung eines zweiten Ausführungsbeispiels des Musters für einen Stent ist; -
7 eine Veranschaulichung eines dritten Ausführungsbeispiels des Musters für den Stent ist; und -
8 eine Veranschaulichung des Musters gemäß7 in einem ausgedehnten Format ist. - Es wird nun Bezug genommen auf die
1 bis4 , welche ein erstes Ausführungsbeispiel eines Stents veranschaulichen, welcher gemäß den Prinzipien der vorliegenden Erfindung aufgebaut und betriebsfähig ist.1 veranschaulicht den Stent in seiner nicht ausgedehnten Form,2 veranschaulicht das Muster des Stents,3 veranschaulicht ihn in einer teilweise gebogenen Stellung, und4 veranschaulicht ihn in einer ausgedehnten Form. - Der Stent gemäß der vorliegenden Erfindung ist eine Röhre, deren Seiten in eine Vielzahl von jeweils zwei senkrechten Mäandermustern ausgebildet sind. wobei die Muster miteinander verschlungen sind. Der Begriff "Mäandermuster" soll hier ein periodisches Muster um eine Mittellinie beschreiben, und "orthogonale Mäandermuster" sind Muster, deren Mittellinien orthogonal zueinander sind.
- Bei dem Stent gemäß
1 bis4 sind die zwei Mäandermuster mit11 und12 bezeichnet, und sie sind am leichtesten aus2 ersichtlich. Das Mäandermuster11 ist eine vertikale Sinusform mit einer vertikalen Mittellinie9 . Das Mäandermuster11 besitzt zwei Schlaufen14 und16 pro Periode, wobei sich die Schlaufen14 nach rechts öffnen, während sich die Schlaufen16 nach links öffnen. Die Schlaufen14 und16 teilen sich gemeinsame Elemente15 und17 , wobei das Element17 sich von einer Schlaufe14 zu seiner nachfolgenden Schlaufe16 verbindet und sich das Element15 von einer Schlaufe16 zu einer nachfolgenden Schlaufe14 verbindet. - Das Mäandermuster
12 ist ein horizontales Muster mit einer horizontalen Mittellinie13 . Das Mäandermuster12 besitzt ebenfalls Schlaufen, welche mit18 und20 bezeichnet sind, zwischen Schlaufen einer Periode liegt jedoch ein ausgedehnter gerader Abschnitt, welcher mit22 bezeichnet ist. Schlaufen18 öffnen sich nach unten, und Schlaufen20 öffnen sich nach oben. Das vertikale Mäandermuster11 ist in ungeraden und geraden (o und e) Versionen vorgesehen, welche 180° außer Phase zueinander sind. Somit weist jede nach links sich öffnende Schlaufe16 des Mäandermusters11o auf eine nach rechts sich öffnende Schlaufe14 des Mäandermusters11e , und eine nach rechts sich öffnende Schlaufe14 des Mäandermusters11o weist auf eine nach links sich öffnende Schlaufe16 des Mäandermusters11e . - Das horizontale Mäandermuster
12 ist ebenfalls in ungeraden und geraden Formen vorgesehen. Die geraden Abschnitte22 des horizontalen Mäandermusters12e schneiden sich mit jedem dritten gemeinsamen Element17 des vertikalen Mäandermusters11e . Die geraden Abschnitte22 des horizontalen Mäandermusters12o schneiden sich mit jedem dritten gemeinsamen Element15 des vertikalen Mäandermusters11e , beginnend mit dem gemeinsamen Element15 , zwei nach einem geschnittenen gemeinsamen Element17 . Das Ergebnis ist eine volle Schlaufe16 ,14 ,16 zwischen den Mäandermustern12e und12o und eine volle Schlaufe14 ,16 ,14 zwischen den Mäandermustern12o und12e . - Zurückkehrend zu
1 ist das Muster gemäß2 in einer Röhre30 eines leicht deformierbaren Materials, wie z. B. Metall, ausgebildet. Infolge der zwei Mäandermuster ist der Stent gemäß1 , wenn er über einen Katheterballon angebracht ist, flexibel und kann demzufolge leicht durch gekrümmte Blutgefäße gezogen werden. Ein Beispiel der Art, in welcher sich der Stent gemäß1 biegt, ist in3 veranschaulicht. - In
3 beginnt sich der Stent an dem mit A bezeichneten Punkt in der Richtung zu biegen, welche durch einen Pfeil40 markiert ist. Wenn sich der Stent zu krümmen beginnt, wird der mit I markierte Abschnitt die Innenseite der Krümmung, während der mit O markierte Abschnitt die Außenseite der Krümmung wird. Die Innenseite der Krümmung I wird gegenüber der Außenseite der Krümmung O verkürzt. - Während des Biegens ändern die Schlaufen
14 bis20 rechts von dem Punkt A die Form, um die Differenzen in der Länge zwischen der Innenkrümmung und der Außenkrümmung auszugleichen. Zum Beispiel sind die Schlaufen18i und20i nahe der Innenseite der Krümmung dichter zusammen als die Schlaufen18o und20o auf der Außenseite der Krümmung, welche sich ausdehnt. Die Schlaufen14i und16i nahe der Innenseite I werden zusammengedrückt, während die Schlaufen14o und16o , welche dichter an der Außenseite O der Krümmung liegen, ausgedehnt werden. - Wie es ersichtlich ist, sind beide Mäandermuster
11 und12 in das Biegen einbezogen. Obwohl es nicht gezeigt ist, ist ersichtlich, daß sich der Stent gemäß den1 bis4 in jegliche Richtung und in mehr als eine Richtung zu jeder Zeit biegen kann. -
4 veranschaulicht den Stent gemäß1 in seiner ausgedehnten Form. Wenn sich der Stent ausdehnt, dehnen sich beide Mäandermuster11 und12 aus (d. h. alle Schlaufen14 bis20 öffnen sich). Wie es ersichtlich ist, besitzt der ausgedehnte Stent zwei Arten von eingeschlossenen Räumen, einen großen Raum42 zwischen den Mäandermustern12o und12e und einen kleinen Raum44 zwischen den Mäandermustern12e und12o . Wie es ebenfalls ersichtlich ist, besitzt jeder große Raum42 zwei Schlaufen14 an seiner linken Seite und zwei Schlaufen16 an seiner rechten Seite. Die großen Räume zwischen den vertikalen Mäandermustern11e und11o , welche mit42a bezeichnet sind, besitzen Schlaufen18 an ihren Oberseiten und Unterseiten, während die großen Räume zwischen den vertikalen Mäandermustern11o und11e , welche mit42b bezeichnet sind, Schlaufen20 an ihren Oberseiten und Unterseiten aufweisen. Gleiches gilt für die kleinen Räume44a und44b . - Es wird festgestellt, daß der Stent gemäß
1 infolge der orthogonalen Mäandermuster11 und12 während der Ausdehnung nicht signifikant schrumpft. Dies ist im Detail in den5A und5B veranschaulicht, auf welche nun Bezug genommen wird.5A veranschaulicht die Bewegung während der Ausdehnung eines vertikalen Mäandermusters11 , und5B veranschaulicht die Bewegung während der Ausdehnung eines horizontalen Mäandermusters12 . Die ursprünglichen Muster sind mit durchgezogenen Linien gezeigt, und die ausgedehnten Muster sind mit gestrichelten Linien gezeigt. - Das vertikale Mäandermuster
11 gemäß5A dehnt sich durch Weiten seiner Schlaufen14 und16 aus. Im Ergebnis wächst das vertikale Mäandermuster11 vertikal um eine Größe 2·h1 pro Schlaufe. Es schrumpft jedoch auch horizontal um eine Größe 2·d1. In ähnlicher Weise dehnt sich das horizontale Mäandermuster12 gemäß5B durch Weiten seiner Schlaufen18 und20 aus. Im Ergebnis wächst das horizontale Mäandermuster12 horizontal um einen Betrag 2·d2 pro Schlaufe. Es schrumpft jedoch auch vertikal um einen Betrag h2. Somit gleicht das vertikale Wachsen des vertikalen Mäandermusters11 zumindest teilweise die vertikale Schrumpfung des horizontalen Mäandermusters12 aus und umgekehrt. Es wird festgestellt, daß die Endabschnitte jedes Stents nur zum Teil kompensiert werden und demzufolge etwas schrumpfen können. - Es ist erkennbar, daß die zwei orthogonalen Mäandermuster
11 und12 und die Kompensation, welche sie gegeneinander schaffen, dem nicht ausgedehnten Stent gemäß1 Flexibilität verleihen. Wenn der Stent ausgedehnt wird, verleihen die Änderungen in jeder Schlaufe14 und16 dem resultierenden Stent Steifigkeit und ermöglichen es somit dem Stent, ein Blutgefäß auf einem gewünschten inneren Durchmesser zu halten. - Der Stent gemäß der vorliegenden Erfindung kann aus flachem Metall hergestellt werden, welches in das Muster gemäß
2 geätzt wird. Das geätzte Metall wird dann in die Form der Röhre30 gebogen. Alternativ kann das Muster gemäß2 aus geschweißtem oder gewundenem Draht hergestellt werden. - Es versteht sich, daß der Stent gemäß der vorliegenden Erfindung aus Metall und/oder Draht hergestellt werden kann. Außerdem kann er mit einem Schutzmaterial beschichtet sein, in welches ein Medikament eingebettet ist. und/oder mit einem Material überzogen sein, welches sich in die Räume
42 und44 einfüllen kann. - Es verstellt sich, daß die vorliegende Erfindung alle Stents umfaßt, welche mit einem Muster hergestellt sind, das aus zwei Mäandermustern ausgebildet ist, welche orthogonal oder anderweitig sind. Ein weiteres beispielhaftes Muster, ebenfalls mit senkrechten Mäandermustern, ist hier vorgesehen, wobei
6 eine schematische Version und7 eine mehr abgerundete Version sind.8 zeigt das Muster gemäß7 in einem ausgedehnten Format. Das Muster gemäß den6 und7 ist ähnlich dem, welches in2 gezeigt ist, außer, daß es mehr horizontale Mäandermuster12 aufweist, wobei sie aus einer einzigen Art bestehen, anstelle gerade und ungerade zu sein, wie in2 . - Wie in beiden
6 und7 ersichtlich ist, gibt es zwei Typen von vertikalen Mäandermustern11e und11o , welche 180° außer Phase zueinander sind. Die horizontalen Mäandermuster12 verbinden sich mit jeder Linie15 des vertikalen Mäandermusters11e . -
8 veranschaulicht das Muster gemäß7 in einem ausgedehnten Format. Da es bei dem ausgedehnten Format gemäß8 keine geraden und ungeraden horizontalen Mäandermuster gibt, gibt es keine großen und kleinen Räume. Anstelle dessen besitzen alle Räume dieselbe Größe.
Claims (5)
- Stent, welcher als Röhre ausgebildet ist und in ein Blutgefäß oder in eine andere Öffnung im Körper einführbar ist, in welchem er ausdehnbar ist, mit folgenden Merkmalen: a) ein oder mehrere ungerade und ein oder mehrere gerade sich abwechselnde Serpentinenabschnitte (
11o ,11e ), von denen jeder erste Biegungsbereiche (14 ,16 ) aufweist, wobei der ungerade Serpentinenabschnitt (11o ) außer Phase mit dem geraden Serpentinenabschnitt (11e ) derart ist, dass erste Biegungsbereiche (14 ,16 ) an dem ungeraden Serpentinenabschnitt (11o ) benachbart zu ersten Biegungsbereichen (16 ,14 ) an dem geraden Serpentinenabschnitt (11e ) sind; und b) zumindest einen flexiblen Verbinder, welcher eine Vielzahl von in Längsrichtung des Stents dehnbaren Verbindungsgliedern in Form von Schlaufen (18 ,20 ) eine Mäandermusters (12 ) aufweist, welche benachbarte erste Biegungsbereiche (14 ,16 ) der benachbarten geraden und ungeraden Serpentinenabschnitten (11e ,11o ) verbinden, wobei jedes flexible Verbindungsglied zumindest zwei Abschnitte (22 ) aufweist, welche durch zumindest einen zweiten Biegungsbereich (18 ,20 ) verbunden sind, und wobei die ersten und zweiten Biegungsbereiche (14 ,16 ;18 ,20 ) erste und zweite Winkel definieren, deren Winkelhalbierende einen Winkel zueinander bilden. - Ballon-expandierbarer und nicht selbst-expan dierender Stent, welcher als Röhre ausgebildet ist und in ein Blutgefäß oder in eine andere Öffnung im Körper einführbar ist, in welchem er ausdehnbar ist, mit einer Struktur aus benachbarten verbundenen, geschlossenen Zellen, wobei jede Zelle aufweist, eine gerade Anzahl von geraden Abschnitten (
22 ) fester Länge, welche mit ersten und zweiten Schlaufen (14 ,16 ;18 ,20 ) abwechseln, die eine feste Länge aufweisen und in einer geschlossenen Zelle verbunden sind, wobei jede Schlaufe zumindest zwei Abschnitte mit einem Biegungsbereich dazwischen aufweist, und wobei die ersten und zweiten Schlaufen (14 ,16 ;18 ,20 ) erste und zweite Winkel definieren deren Winkelhalbierende einen Winkel zueinander bilden. - Stent nach Anspruch 1 oder 2, welcher aus Draht gebildet ist.
- Stent nach Anspruch 1 oder 2, welcher aus flachem Metall geschnitten ist.
- Stent nach einem der Ansprüche 1 bis 4, bei dem der Stent mit einem Schutzmaterial beschichtet ist, in welches ein Medikament eingebettet ist, und/oder mit einem Material überzogen ist.
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28218194A | 1994-07-28 | 1994-07-28 | |
US08/282181 | 1994-07-28 | ||
US08/457354 | 1995-05-31 | ||
US08/457,354 US5733303A (en) | 1994-03-17 | 1995-05-31 | Flexible expandable stent |
EP95929314A EP0762856B1 (de) | 1994-07-28 | 1995-07-26 | Flexibler, expandierbarer stent |
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DE19581503 | 1995-07-26 |
Publications (3)
Publication Number | Publication Date |
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DE19549520B4 DE19549520B4 (de) | 2005-04-14 |
DE19549520C9 true DE19549520C9 (de) | 2009-01-29 |
DE19549520C5 DE19549520C5 (de) | 2015-01-08 |
Family
ID=26961291
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Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE29521205U Expired - Lifetime DE29521205U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler ausdehnbarer Stent |
DE29521206U Expired - Lifetime DE29521206U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler ausdehnbarer Stent |
DE69525072T Revoked DE69525072T2 (de) | 1994-07-28 | 1995-07-26 | Flexibler, expandierbarer Stent |
DE29522342U Expired - Lifetime DE29522342U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler, ausdehnbarer Stent |
DE19581503T Expired - Lifetime DE19581503C2 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler ausdehnbarer Stent |
DE69524638T Revoked DE69524638T2 (de) | 1994-07-28 | 1995-07-26 | Flexibler, expandierbarer Stent |
DE29521193U Expired - Lifetime DE29521193U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler ausdehnbarer Stent |
DE69533931T Expired - Lifetime DE69533931T3 (de) | 1994-07-28 | 1995-07-26 | Flexibler expandierbarer Stent |
DE29522344U Expired - Lifetime DE29522344U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler, ausdehnbarer Stent |
DE29522345U Expired - Lifetime DE29522345U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler, ausdehnbarer Stent |
DE19549477.6A Expired - Lifetime DE19549477C5 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler ausdehnbarer Stent |
DE69534608T Expired - Lifetime DE69534608T2 (de) | 1994-07-28 | 1995-07-26 | Flexibler expandierbarer Stent |
DE69504659T Revoked DE69504659T2 (de) | 1994-07-28 | 1995-07-26 | Flexibler, expandierbarer stent |
DE19549520A Expired - Lifetime DE19549520C5 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler ausdehnbarer Stent |
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Application Number | Title | Priority Date | Filing Date |
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DE29521205U Expired - Lifetime DE29521205U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler ausdehnbarer Stent |
DE29521206U Expired - Lifetime DE29521206U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler ausdehnbarer Stent |
DE69525072T Revoked DE69525072T2 (de) | 1994-07-28 | 1995-07-26 | Flexibler, expandierbarer Stent |
DE29522342U Expired - Lifetime DE29522342U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler, ausdehnbarer Stent |
DE19581503T Expired - Lifetime DE19581503C2 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler ausdehnbarer Stent |
DE69524638T Revoked DE69524638T2 (de) | 1994-07-28 | 1995-07-26 | Flexibler, expandierbarer Stent |
DE29521193U Expired - Lifetime DE29521193U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler ausdehnbarer Stent |
DE69533931T Expired - Lifetime DE69533931T3 (de) | 1994-07-28 | 1995-07-26 | Flexibler expandierbarer Stent |
DE29522344U Expired - Lifetime DE29522344U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler, ausdehnbarer Stent |
DE29522345U Expired - Lifetime DE29522345U1 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler, ausdehnbarer Stent |
DE19549477.6A Expired - Lifetime DE19549477C5 (de) | 1994-07-28 | 1995-07-26 | Ein flexibler ausdehnbarer Stent |
DE69534608T Expired - Lifetime DE69534608T2 (de) | 1994-07-28 | 1995-07-26 | Flexibler expandierbarer Stent |
DE69504659T Revoked DE69504659T2 (de) | 1994-07-28 | 1995-07-26 | Flexibler, expandierbarer stent |
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Application Number | Title | Priority Date | Filing Date |
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DE69525182.1T Expired - Lifetime DE69525182C5 (de) | 1994-07-28 | 1995-07-26 | Flexibler, expandierbarer Stent |
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US (1) | US5733303A (de) |
EP (9) | EP1181901B1 (de) |
JP (5) | JP3236623B2 (de) |
KR (1) | KR970704387A (de) |
CN (1) | CN1119975C (de) |
AT (6) | ATE308945T1 (de) |
AU (2) | AU702468B2 (de) |
BR (1) | BR9508353A (de) |
CA (5) | CA2365589C (de) |
CH (4) | CH693439A5 (de) |
CZ (1) | CZ288740B6 (de) |
DE (15) | DE29521205U1 (de) |
DK (5) | DK0762856T3 (de) |
EE (1) | EE03416B1 (de) |
ES (4) | ES2123285T3 (de) |
FI (1) | FI970316A (de) |
GB (2) | GB2315415B (de) |
HK (3) | HK1001756A1 (de) |
LU (1) | LU90031B1 (de) |
NO (1) | NO312122B1 (de) |
NZ (1) | NZ291543A (de) |
PL (1) | PL180527B1 (de) |
PT (3) | PT846452E (de) |
RO (1) | RO117899B1 (de) |
SE (1) | SE515118C2 (de) |
SI (1) | SI9520079B (de) |
SK (1) | SK283134B6 (de) |
UA (1) | UA45355C2 (de) |
WO (1) | WO1996003092A1 (de) |
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1995
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- 1995-07-26 DE DE29521205U patent/DE29521205U1/de not_active Expired - Lifetime
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- 1995-07-26 EP EP01122700A patent/EP1181901B1/de not_active Revoked
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- 1995-07-26 DE DE69525072T patent/DE69525072T2/de not_active Revoked
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- 1995-07-26 DK DK95929314T patent/DK0762856T3/da active
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- 1995-07-26 WO PCT/US1995/008975 patent/WO1996003092A1/en not_active Application Discontinuation
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1997
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- 1997-01-28 LU LU90031A patent/LU90031B1/de active
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1998
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1999
- 1999-03-25 JP JP11081198A patent/JPH11319112A/ja active Pending
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2001
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2002
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2005
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