DE1904894C3 - Verfahren zur Herstellung von 3-Amino-4-carboxamido-pyrazolen - Google Patents

Verfahren zur Herstellung von 3-Amino-4-carboxamido-pyrazolen

Info

Publication number
DE1904894C3
DE1904894C3 DE1904894A DE1904894A DE1904894C3 DE 1904894 C3 DE1904894 C3 DE 1904894C3 DE 1904894 A DE1904894 A DE 1904894A DE 1904894 A DE1904894 A DE 1904894A DE 1904894 C3 DE1904894 C3 DE 1904894C3
Authority
DE
Germany
Prior art keywords
amino
carboxamido
hydrazine
preparation
pyrazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1904894A
Other languages
German (de)
English (en)
Other versions
DE1904894A1 (de
DE1904894B2 (de
Inventor
John William Hartsdale N.Y. Mentha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of DE1904894A1 publication Critical patent/DE1904894A1/de
Publication of DE1904894B2 publication Critical patent/DE1904894B2/de
Application granted granted Critical
Publication of DE1904894C3 publication Critical patent/DE1904894C3/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE1904894A 1968-02-02 1969-01-31 Verfahren zur Herstellung von 3-Amino-4-carboxamido-pyrazolen Expired DE1904894C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB539768A GB1252435A (US07122603-20061017-C00045.png) 1968-02-02 1968-02-02

Publications (3)

Publication Number Publication Date
DE1904894A1 DE1904894A1 (de) 1970-01-15
DE1904894B2 DE1904894B2 (de) 1979-01-18
DE1904894C3 true DE1904894C3 (de) 1983-06-16

Family

ID=9795384

Family Applications (3)

Application Number Title Priority Date Filing Date
DE1921676A Expired DE1921676C2 (de) 1968-02-02 1969-01-31 2-Cyano-3-morpholinoacrylsäure-Derivate und Verfahren zu ihrer Herstellung
DE1966640A Expired DE1966640C3 (de) 1968-02-02 1969-01-31 Verfahren zur Herstellung von 4- Hydroxy- und 4,6-Dihydroxy-pyrazolo eckige Klammer auf 3,4-d eckige Klammer zu pyrimidinen
DE1904894A Expired DE1904894C3 (de) 1968-02-02 1969-01-31 Verfahren zur Herstellung von 3-Amino-4-carboxamido-pyrazolen

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE1921676A Expired DE1921676C2 (de) 1968-02-02 1969-01-31 2-Cyano-3-morpholinoacrylsäure-Derivate und Verfahren zu ihrer Herstellung
DE1966640A Expired DE1966640C3 (de) 1968-02-02 1969-01-31 Verfahren zur Herstellung von 4- Hydroxy- und 4,6-Dihydroxy-pyrazolo eckige Klammer auf 3,4-d eckige Klammer zu pyrimidinen

Country Status (18)

Country Link
US (1) US3682957A (US07122603-20061017-C00045.png)
JP (3) JPS509798B1 (US07122603-20061017-C00045.png)
BE (1) BE727754A (US07122603-20061017-C00045.png)
BR (1) BR6906061D0 (US07122603-20061017-C00045.png)
CA (1) CA931568A (US07122603-20061017-C00045.png)
CH (1) CH507266A (US07122603-20061017-C00045.png)
CY (1) CY694A (US07122603-20061017-C00045.png)
DE (3) DE1921676C2 (US07122603-20061017-C00045.png)
DK (1) DK135534B (US07122603-20061017-C00045.png)
ES (2) ES363208A1 (US07122603-20061017-C00045.png)
FR (1) FR2001211A1 (US07122603-20061017-C00045.png)
GB (1) GB1252435A (US07122603-20061017-C00045.png)
GT (1) GT198274955A (US07122603-20061017-C00045.png)
IE (1) IE33130B1 (US07122603-20061017-C00045.png)
IL (2) IL37414A (US07122603-20061017-C00045.png)
MY (1) MY7500063A (US07122603-20061017-C00045.png)
NL (1) NL139664B (US07122603-20061017-C00045.png)
SE (2) SE362429B (US07122603-20061017-C00045.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK115374A (US07122603-20061017-C00045.png) 1974-03-04 1975-11-03 Byk Gulden Lomberg Chem Fab
JPS5481278A (en) * 1977-10-18 1979-06-28 Wellcome Found Manufacture of triiseccaminomethane
US4282361A (en) * 1978-03-16 1981-08-04 Massachusetts Institute Of Technology Synthesis for 7-alkylamino-3-methylpyrazolo [4,3-d]pyrimidines
US4267324A (en) * 1979-06-20 1981-05-12 Polaroid Corporation Process for preparing 4-aminopyrazolo-(3,4-d)pyrimidine
CH654009A5 (de) * 1983-03-21 1986-01-31 Siegfried Ag Verfahren zur herstellung von allopurinol.
EP1044002A4 (en) 1997-11-07 2003-05-02 Univ Johns Hopkins METHODS FOR THE TREATMENT OF HEART CONTRACTILITY
CN102643279A (zh) * 2012-02-09 2012-08-22 临海市恒源化工有限公司 一种别嘌醇的合成方法
CN103965197B (zh) * 2013-04-15 2016-07-06 杭州领业医药科技有限公司 别嘌醇晶体制备
CN104387394A (zh) * 2014-11-26 2015-03-04 千辉药业(安徽)有限责任公司 一种别嘌醇的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1070635B (de) 1959-12-10 Ciba Aktiengesellschaft, Basel (Schweiz) Verfahren zur Herstellung von 1,5-unsubstituierten 3-Amiinopymzolen
US3187006A (en) * 1956-04-17 1965-06-01 Ciba Geigy Corp N-substituted pyrazoles and method of preparing same
AT200575B (de) * 1957-01-02 1958-11-10 Ciba Geigy Verfahren zur Herstellung von neuen 3-Amino-pyrazol-derivaten
LU38903A1 (US07122603-20061017-C00045.png) * 1959-07-03
US3169966A (en) * 1961-01-24 1965-02-16 Ciba Geigy Corp Aminopyrazoles
GB1200444A (en) * 1966-07-14 1970-07-29 Burroughs Wellcome Co The preparation of pyrazoles and pyrazolopyrimidines

Also Published As

Publication number Publication date
US3682957A (en) 1972-08-08
IL37414A (en) 1971-11-29
SE362429B (US07122603-20061017-C00045.png) 1973-12-10
IE33130B1 (en) 1974-04-03
DE1921676C2 (de) 1985-05-30
SE380802B (sv) 1975-11-17
DE1966640C3 (de) 1985-05-15
DE1966640A1 (de) 1973-08-09
JPS5026550B1 (US07122603-20061017-C00045.png) 1975-09-01
BE727754A (US07122603-20061017-C00045.png) 1969-07-31
BR6906061D0 (pt) 1973-04-19
DE1966640B2 (de) 1977-08-11
ES363208A1 (es) 1970-12-16
GB1252435A (US07122603-20061017-C00045.png) 1971-11-03
JPS509798B1 (US07122603-20061017-C00045.png) 1975-04-16
CH507266A (de) 1971-05-15
ES380767A1 (es) 1972-09-16
IL31524A (en) 1971-11-29
GT198274955A (es) 1983-10-18
JPS523955B1 (US07122603-20061017-C00045.png) 1977-01-31
NL139664B (nl) 1973-09-17
CA931568A (en) 1973-08-07
DK135534C (US07122603-20061017-C00045.png) 1977-10-24
DE1921676A1 (de) 1969-09-18
MY7500063A (en) 1975-12-31
DE1904894A1 (de) 1970-01-15
NL6901564A (US07122603-20061017-C00045.png) 1969-08-05
IE33130L (en) 1969-08-02
FR2001211A1 (US07122603-20061017-C00045.png) 1969-09-26
DE1904894B2 (de) 1979-01-18
CY694A (en) 1973-08-10
IL31524A0 (en) 1969-03-27
DK135534B (da) 1977-05-16

Similar Documents

Publication Publication Date Title
DE2902438C2 (US07122603-20061017-C00045.png)
DE1904894C3 (de) Verfahren zur Herstellung von 3-Amino-4-carboxamido-pyrazolen
DE2845435A1 (de) Verfahren zur herstellung von 2,6-diaminonebularinen
DE1795720A1 (de) Verfahren zur herstellung von 4und/oder 4,6-dihydroxy-pyrazolo-(3,4) pyrimidinen
DE2121694B2 (de) Diamino-s-triazinderivate, ein verfahren zu deren herstellung und diese enthaltende therapeutische zubereitungen
DE1814082C3 (de) Herstellung und ihre Weiterverarbeitung zu Pyrazolopyrimidinen
DE3330192A1 (de) 4-alkylimidazol-derivate, ihre herstellung und verwendung
DE946806C (de) Verfahren zur Herstellung von 3, 6-Dihydrazino-pyridazin
AT217048B (de) Verfahren zur Herstellung von neuen in 7-Stellung substituierten Theophyllin-Derivaten
DE3514703A1 (de) N-benzyloxycarbonyl-l-threoninamid-hemihydrat, verfahren zu seiner herstellung und seine verwendung
DE1928144C3 (de) Verfahren zur Herstellung von wasserfreien 6-(1-Aminocycloalkylcarboxamido)-penicillansäuren
CH583714A5 (de) Verfahren zur herstellung von neuem 1-veratryl-4-methyl5-aethyl-7,8-dimethoxy-2,3-diazabicyclo(5,4,0)-undecapentaen-(1,3,6,8,10).
DE2539866C2 (de) 3,4-Dehydro-14,15-dihydro-eburnameninderivate
AT204047B (de) Verfahren zur Herstellung neuer Triazine
AT218526B (de) Verfahren zur Herstellung von neuen Phenthiazinderivaten
DE1795610C3 (de) Verfahren zur Herstellung von kristallinem, nicht hygroskopischen Cephaloridin
DE908020C (de) Verfahren zur Herstellung von 2-Amino-pyridinverbindungen
DE945237C (de) Verfahren zur Herstellung von Pyrrolinonen
AT205963B (de) Verfahren zur Herstellung von substituierten Aminosäurehydraziden
DE910654C (de) Verfahren zur Herstellung von 2-Halogenarylamino-4-amino-1,3, 5-triazinderivaten
DE1065421B (de) Verfahren zur Herstellung von alkylierten Hydropyrazolo [3,4-d] pyrimidinen
DE1154487B (de) Verfahren zur Herstellung von 5-Nitrofuryl-(2)-methylketon
DE2940037A1 (de) Monomeres n-methylenaminoacetonitril und verfahren zu seiner herstellung
DE3808355A1 (de) 1-naphthoesaeure und deren funktionelle verbindungen, verfahren zu ihrer herstellung und ihre verwendung als pflanzenschutzmittel
DE1768880A1 (de) N,N'-Bis-(phenyl)oxamidrazon

Legal Events

Date Code Title Description
SH Request for examination between 03.10.1968 and 22.04.1971
8381 Inventor (new situation)

Free format text: CRESSWELL, RONALD MORTON, DR., SCARSDALE, N.Y., US MENTHA, JOHN WILLIAM, HARTSDALE, N.Y., US SEAMAN, RUSSEL, CHAPPAQUA, N.Y., US

C3 Grant after two publication steps (3rd publication)
AH Division in

Ref country code: DE

Ref document number: 1966640

Format of ref document f/p: P