DE1795711C3 - Substituierte Benzimidazole, Verfahren zu deren Herstellung sowie diese enthaltende anthelminthische Zusammensetzungen - Google Patents

Substituierte Benzimidazole, Verfahren zu deren Herstellung sowie diese enthaltende anthelminthische Zusammensetzungen

Info

Publication number
DE1795711C3
DE1795711C3 DE1795711A DE1795711A DE1795711C3 DE 1795711 C3 DE1795711 C3 DE 1795711C3 DE 1795711 A DE1795711 A DE 1795711A DE 1795711 A DE1795711 A DE 1795711A DE 1795711 C3 DE1795711 C3 DE 1795711C3
Authority
DE
Germany
Prior art keywords
benzimidazole
preparation
compound
processes
thiazolyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1795711A
Other languages
German (de)
English (en)
Other versions
DE1795711A1 (de
DE1795711B2 (de
Inventor
H Fisher
D R Hoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE1795711A1 publication Critical patent/DE1795711A1/de
Publication of DE1795711B2 publication Critical patent/DE1795711B2/de
Application granted granted Critical
Publication of DE1795711C3 publication Critical patent/DE1795711C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • E—FIXED CONSTRUCTIONS
    • E21—EARTH OR ROCK DRILLING; MINING
    • E21D—SHAFTS; TUNNELS; GALLERIES; LARGE UNDERGROUND CHAMBERS
    • E21D11/00—Lining tunnels, galleries or other underground cavities, e.g. large underground chambers; Linings therefor; Making such linings in situ, e.g. by assembling
    • E21D11/14—Lining predominantly with metal
    • E21D11/28—Longitudinal struts, i.e. longitudinal connections between adjoining arches

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mining & Mineral Resources (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Geochemistry & Mineralogy (AREA)
  • Civil Engineering (AREA)
  • Architecture (AREA)
  • Medicinal Chemistry (AREA)
  • Structural Engineering (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE1795711A 1967-02-03 1968-02-02 Substituierte Benzimidazole, Verfahren zu deren Herstellung sowie diese enthaltende anthelminthische Zusammensetzungen Expired DE1795711C3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61374667A 1967-02-03 1967-02-03
US69649668A 1968-01-09 1968-01-09

Publications (3)

Publication Number Publication Date
DE1795711A1 DE1795711A1 (de) 1974-02-28
DE1795711B2 DE1795711B2 (de) 1978-09-21
DE1795711C3 true DE1795711C3 (de) 1979-05-17

Family

ID=27087090

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1795711A Expired DE1795711C3 (de) 1967-02-03 1968-02-02 Substituierte Benzimidazole, Verfahren zu deren Herstellung sowie diese enthaltende anthelminthische Zusammensetzungen
DE1695545A Expired DE1695545C3 (de) 1967-02-03 1968-02-02 Substituierte Benzimidazole, Verfahren zu deren Herstellung sowie deren Verwendung bei der Bekämpfung von Wurmerkrankungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE1695545A Expired DE1695545C3 (de) 1967-02-03 1968-02-02 Substituierte Benzimidazole, Verfahren zu deren Herstellung sowie deren Verwendung bei der Bekämpfung von Wurmerkrankungen

Country Status (19)

Country Link
AT (5) AT289833B (enExample)
BE (2) BE710081A (enExample)
CH (5) CH509318A (enExample)
CS (1) CS162651B2 (enExample)
CY (1) CY653A (enExample)
DE (2) DE1795711C3 (enExample)
DK (1) DK139940B (enExample)
ES (4) ES350083A1 (enExample)
FI (1) FI52859C (enExample)
FR (1) FR1580153A (enExample)
GB (2) GB1198942A (enExample)
IE (1) IE31812B1 (enExample)
IT (1) IT1044176B (enExample)
NL (1) NL157015B (enExample)
NO (1) NO126484B (enExample)
OA (1) OA04036A (enExample)
SE (1) SE346321B (enExample)
SU (1) SU540569A3 (enExample)
YU (1) YU33831B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3711608A (en) * 1971-04-13 1973-01-16 Merck & Co Inc The treatment of pain, fever and inflammation with benzimidazoles
US3985755A (en) * 1972-06-02 1976-10-12 E. R. Squibb & Sons, Inc. Pyridine containing isothiocyanobenzoxazoles
US3983130A (en) * 1972-06-02 1976-09-28 E. R. Squibb & Sons, Inc. Anthelmintic isothiocyanobenzoxazoles
US3853894A (en) * 1972-06-02 1974-12-10 Squibb & Sons Inc Isothiocyanobenzimidazoles
MA19290A1 (fr) * 1980-05-22 1982-04-01 Ciba Geigy Ag Derives du benzole,leur preparaton et leur utilisations therapeutiques .
SE8604566D0 (sv) * 1986-10-27 1986-10-27 Haessle Ab Novel compunds
US7622592B2 (en) 2002-11-01 2009-11-24 Merck & Co., Inc. Carbonylamino-benzimidazole derivatives as androgen receptor modulators
EP1675844A1 (en) * 2003-10-23 2006-07-05 Sterix Limited Phenyl carboxamide and sulfonamide derivatives for use as 11-beta-hydroxysteroid dehydrogenase
GB0324792D0 (en) 2003-10-23 2003-11-26 Sterix Ltd Compound
TWI356055B (en) * 2003-12-18 2012-01-11 Tibotec Pharm Ltd Aminobenzimidazoles and benzimidazoles as inhibito
CN101142208B (zh) * 2005-03-17 2012-05-23 泰博特克药品有限公司 作为呼吸道合胞病毒复制抑制剂的1,3-二氢-苯并咪唑-2-亚基胺

Also Published As

Publication number Publication date
DE1695545C3 (de) 1979-05-03
IE31812B1 (en) 1973-01-10
IT1044176B (it) 1980-03-20
YU21268A (en) 1977-12-31
IE31812L (en) 1968-08-03
NL6801482A (enExample) 1968-08-05
DE1795711A1 (de) 1974-02-28
CY653A (en) 1972-08-31
CH545796A (enExample) 1974-02-15
DE1695545A1 (de) 1971-05-06
ES350083A1 (es) 1969-11-16
AT289828B (de) 1971-05-10
GB1198941A (en) 1970-07-15
SE346321B (enExample) 1972-07-03
GB1198942A (en) 1970-07-15
AT289833B (de) 1971-05-10
AT289835B (de) 1971-05-10
CH509318A (de) 1971-06-30
BE710081A (enExample) 1968-07-30
NL157015B (nl) 1978-06-15
CH545293A (de) 1974-01-31
ES363760A1 (es) 1970-12-16
OA04036A (fr) 1979-09-30
DK139940C (enExample) 1979-10-15
CH545294A (de) 1974-01-31
NO126484B (enExample) 1973-02-12
ES363761A1 (es) 1970-12-16
BE735281A (enExample) 1969-12-29
FI52859B (enExample) 1977-08-31
ES363762A1 (es) 1970-12-16
DE1795711B2 (de) 1978-09-21
AT293378B (de) 1971-10-11
YU33831B (en) 1978-06-30
DK139940B (da) 1979-05-21
AT301244B (de) 1972-08-25
CH545295A (de) 1974-01-31
DE1695545B2 (de) 1978-08-31
FR1580153A (enExample) 1969-09-05
SU540569A3 (ru) 1976-12-25
CS162651B2 (enExample) 1975-07-15
FI52859C (fi) 1977-12-12

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8339 Ceased/non-payment of the annual fee