DE1793662C3 - 4 Pregnen 3,20 dion eckige Klammer auf 17 alpha, 16 alpha d eckige Klammer zu 2' methyloxazohn und Verfahren zu seiner Herstellung Ausscheidung aus 1568950 - Google Patents

4 Pregnen 3,20 dion eckige Klammer auf 17 alpha, 16 alpha d eckige Klammer zu 2' methyloxazohn und Verfahren zu seiner Herstellung Ausscheidung aus 1568950

Info

Publication number
DE1793662C3
DE1793662C3 DE1793662A DE1793662A DE1793662C3 DE 1793662 C3 DE1793662 C3 DE 1793662C3 DE 1793662 A DE1793662 A DE 1793662A DE 1793662 A DE1793662 A DE 1793662A DE 1793662 C3 DE1793662 C3 DE 1793662C3
Authority
DE
Germany
Prior art keywords
alpha
square bracket
pregnen
methyloxazoline
methyloxazohn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE1793662A
Other languages
German (de)
English (en)
Other versions
DE1793662A1 (de
DE1793662B2 (de
Inventor
Giangiacomo Nathansohn
Giorgio Winters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of DE1793662A1 publication Critical patent/DE1793662A1/de
Publication of DE1793662B2 publication Critical patent/DE1793662B2/de
Application granted granted Critical
Publication of DE1793662C3 publication Critical patent/DE1793662C3/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0027—Azides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/0025—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16
    • C07J7/0035—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16 by a hydroxy group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring
    • C07J71/0057—Nitrogen and oxygen
    • C07J71/0068—Nitrogen and oxygen at position 16(17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Machines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE1793662A 1965-04-22 1966-04-20 4 Pregnen 3,20 dion eckige Klammer auf 17 alpha, 16 alpha d eckige Klammer zu 2' methyloxazohn und Verfahren zu seiner Herstellung Ausscheidung aus 1568950 Expired DE1793662C3 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB17027/65A GB1077392A (en) 1965-04-22 1965-04-22 New steroids
GB3586565 1965-08-20

Publications (3)

Publication Number Publication Date
DE1793662A1 DE1793662A1 (de) 1972-08-03
DE1793662B2 DE1793662B2 (de) 1973-04-19
DE1793662C3 true DE1793662C3 (de) 1973-11-08

Family

ID=26252388

Family Applications (3)

Application Number Title Priority Date Filing Date
DE1793662A Expired DE1793662C3 (de) 1965-04-22 1966-04-20 4 Pregnen 3,20 dion eckige Klammer auf 17 alpha, 16 alpha d eckige Klammer zu 2' methyloxazohn und Verfahren zu seiner Herstellung Ausscheidung aus 1568950
DE19661568950 Pending DE1568950A1 (de) 1965-04-22 1966-04-20 Steroid-[17alpha,16alpha-d]-oxazoline und Verfahren zu ihrer Herstellung
DE19661568951 Pending DE1568951A1 (de) 1965-04-22 1966-04-21 Verfahren zur Herstellung von Steroid[17alpha,16alphad]-oxazolinen

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE19661568950 Pending DE1568950A1 (de) 1965-04-22 1966-04-20 Steroid-[17alpha,16alpha-d]-oxazoline und Verfahren zu ihrer Herstellung
DE19661568951 Pending DE1568951A1 (de) 1965-04-22 1966-04-21 Verfahren zur Herstellung von Steroid[17alpha,16alphad]-oxazolinen

Country Status (15)

Country Link
US (2) US3436389A (OSRAM)
AT (2) AT260440B (OSRAM)
BE (2) BE679820A (OSRAM)
BR (2) BR6678805D0 (OSRAM)
CH (2) CH471833A (OSRAM)
DE (3) DE1793662C3 (OSRAM)
DK (2) DK117631B (OSRAM)
ES (1) ES325755A1 (OSRAM)
FI (2) FI44906C (OSRAM)
FR (1) FR5645M (OSRAM)
GB (1) GB1077392A (OSRAM)
IL (2) IL25493A (OSRAM)
NL (3) NL6605174A (OSRAM)
NO (2) NO127346B (OSRAM)
SE (2) SE323674B (OSRAM)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1119081A (en) * 1966-01-11 1968-07-10 Lepetit Spa New steroids
IT1141930B (it) * 1980-04-28 1986-10-08 Lepetit Spa Esteri idrosolubili di steroido-ossazoli e loro composizioni farmaceutiche
IT1134455B (it) * 1980-11-26 1986-08-13 Lepetit Spa Procedimento per la preparazione di derivati 16alfa-idrossi-17alfa-aminopregnanici
RU2387646C2 (ru) * 2003-08-29 2010-04-27 Рэнбакси Лабораториз Лимитед Ингибиторы фосфодиэстеразы типа-iv
US20070259874A1 (en) * 2003-11-26 2007-11-08 Palle Venkata P Phosphodiesterase Inhibitors
US20080009535A1 (en) * 2004-08-30 2008-01-10 Sarala Balachandran Inhibitors of phosphodiesterase type-IV
US7915286B2 (en) 2005-09-16 2011-03-29 Ranbaxy Laboratories Limited Substituted pyrazolo [3,4-b] pyridines as phosphodiesterase inhibitors
EP1948164A1 (en) 2005-10-19 2008-07-30 Ranbaxy Laboratories, Ltd. Pharmaceutical compositions of muscarinic receptor antagonists
AU2006305620A1 (en) * 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors
KR20090069309A (ko) * 2006-09-22 2009-06-30 랜박시 래보러터리스 리미티드 포스포디에스터라제 타입-ⅳ의 저해제
EP2066661A2 (en) * 2006-09-22 2009-06-10 Ranbaxy Laboratories Limited Phosphodiesterase inhibitors
CN101177443B (zh) * 2006-11-09 2011-08-03 天津药业研究院有限公司 新的甾体化合物及其应用
EP1958947A1 (en) 2007-02-15 2008-08-20 Ranbaxy Laboratories Limited Inhibitors of phosphodiesterase type 4
JP5671236B2 (ja) 2007-03-14 2015-02-18 ランバクシー ラボラトリーズ リミテッド ホスホジエステラーゼ阻害剤としてのピラゾロ（３，４−ｂ）ピリジン誘導体
EP2124943A1 (en) * 2007-03-14 2009-12-02 Ranbaxy Laboratories Limited Pyrazolo [3, 4-b]pyridine derivatives as phosphodiesterase inhibitors
EP2111861A1 (en) 2008-04-21 2009-10-28 Ranbaxy Laboratories Limited Compositions of phosphodiesterase type IV inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2874154A (en) * 1954-10-15 1959-02-17 Syntex Sa Process for the production of 20-keto-21-iodo steroids
US2923721A (en) * 1955-12-13 1960-02-02 Lab Francais Chimiotherapie Method of preparing 3-keto delta1, 4 steroids
DE1223376B (de) * 1963-12-14 1966-08-25 Hoechst Ag Verfahren zur Herstellung von 17alpha-Cyan-16alpha-hydroxy-steroiden der Pregnanreihe
US3349084A (en) * 1965-05-17 1967-10-24 Upjohn Co Steroidal [16, 17-d]-2'-isoxazolines of the pregnane series

Also Published As

Publication number Publication date
BE679820A (OSRAM) 1966-10-03
SE323675B (OSRAM) 1970-05-11
CH471833A (fr) 1969-04-30
NL6605174A (OSRAM) 1966-10-24
SE323674B (OSRAM) 1970-05-11
FI44906C (fi) 1972-02-10
BR6679615D0 (pt) 1973-10-23
IL25493A (en) 1969-12-31
IL25494A (en) 1970-03-22
FI44905C (fi) 1972-02-10
FR5645M (OSRAM) 1967-12-26
AT260440B (de) 1968-03-11
BR6678805D0 (pt) 1973-09-18
NL6605375A (OSRAM) 1966-10-24
NL128816C (OSRAM)
NO127346B (OSRAM) 1973-06-12
DK116870B (da) 1970-02-23
DE1568951A1 (de) 1970-06-18
CH453351A (fr) 1968-06-14
GB1077392A (en) 1967-07-26
BE679821A (OSRAM) 1966-10-03
AT265539B (de) 1968-10-10
DK117631B (da) 1970-05-19
DE1793662A1 (de) 1972-08-03
NO128152B (OSRAM) 1973-10-08
DE1793662B2 (de) 1973-04-19
ES325755A1 (es) 1967-02-16
FI44905B (OSRAM) 1971-11-01
FI44906B (OSRAM) 1971-11-01
US3413286A (en) 1968-11-26
US3436389A (en) 1969-04-01
DE1568950A1 (de) 1970-11-26

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
E77 Valid patent as to the heymanns-index 1977