DE1267218B - Verfahren zur Herstellung von 19-Oxy-delta 4-3-keto-steroiden der Androstan- bzw. Pregnanreihe - Google Patents

Verfahren zur Herstellung von 19-Oxy-delta 4-3-keto-steroiden der Androstan- bzw. Pregnanreihe

Info

Publication number
DE1267218B
DE1267218B DEP1267A DE1267218A DE1267218B DE 1267218 B DE1267218 B DE 1267218B DE P1267 A DEP1267 A DE P1267A DE 1267218 A DE1267218 A DE 1267218A DE 1267218 B DE1267218 B DE 1267218B
Authority
DE
Germany
Prior art keywords
triol
vol
oxy
keto
diol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DEP1267A
Other languages
German (de)
English (en)
Inventor
Dr Albert Bowers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Palo Alto LLC filed Critical Roche Palo Alto LLC
Publication of DE1267218B publication Critical patent/DE1267218B/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
DEP1267A 1962-05-16 1963-05-14 Verfahren zur Herstellung von 19-Oxy-delta 4-3-keto-steroiden der Androstan- bzw. Pregnanreihe Pending DE1267218B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX6742362 1962-05-16

Publications (1)

Publication Number Publication Date
DE1267218B true DE1267218B (de) 1968-05-02

Family

ID=19742935

Family Applications (1)

Application Number Title Priority Date Filing Date
DEP1267A Pending DE1267218B (de) 1962-05-16 1963-05-14 Verfahren zur Herstellung von 19-Oxy-delta 4-3-keto-steroiden der Androstan- bzw. Pregnanreihe

Country Status (6)

Country Link
US (1) US3145202A (enExample)
BE (1) BE632431A (enExample)
CH (1) CH450405A (enExample)
DE (1) DE1267218B (enExample)
GB (1) GB1008168A (enExample)
NL (1) NL292848A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH433275A (de) * 1963-07-09 1967-04-15 Hoffmann La Roche Verfahren zur Herstellung von 19-Alkylsteroiden
FR2650204B1 (fr) * 1989-07-26 1993-07-16 Saint Gobain Isover Procede et dispositif pour le traitement de dechets de verre ou de fibres minerales en vue de leur recuperation
US9630986B2 (en) * 2012-12-18 2017-04-25 Washington University Neuroactive 19-alkoxy-17-substituted steroids, prodrugs thereof, and methods of treatment using same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2384335A (en) * 1936-05-26 1945-09-04 Oppenauer Rupert Process for oxidizing unsaturated polycyclic alcohols

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Also Published As

Publication number Publication date
US3145202A (en) 1964-08-18
BE632431A (enExample)
GB1008168A (en) 1965-10-27
NL292848A (enExample)
CH450405A (de) 1968-01-31

Similar Documents

Publication Publication Date Title
DE1267218B (de) Verfahren zur Herstellung von 19-Oxy-delta 4-3-keto-steroiden der Androstan- bzw. Pregnanreihe
DE1222920B (de) Verfahren zur Herstellung von in 3-Stellung durch einen sauerstoffhaltigen Substituenten substituierten 19-Methylenderivaten der Androstanreihe
DE1239306B (de) Verfahren zur Herstellung von Ketosteroiden, die in alpha-Stellung zur Ketogruppe eine gegebenenfalls substituierte Allylgruppe tragen
DE1568502C3 (de) 3-Cyanmethylen-androstene und -östrene und Verfahren zu ihrer Herstellung
DE957661C (de) Verfahren zur Herstellung von 17-Oxy-20-keto-21acyl-oxypregnanen
DE1543992C3 (de) Verfahren zur Herstellung von Equilin
DE752690C (de) Verfahren zur Herstellung von Verbindungen der Cortinreihe
DE955504C (de) Verfahren zur Herstellung von 17 ª‡-Oxy-20-keto-21-acyloxysteroiden
DE1793676C2 (de) Verfahren zur Herstellung von Delta 4-bzw. Delta 5-ungesättigten Steroiden der Androstan-, Pregnan- und Sapogeninreihe mit einer Carboxylgruppe in 19-Stellung
AT228410B (de) Verfahren zur Herstellung neuer 6-Methyl-3-oxo-4, 6-dien-steroide
DE1043333B (de) Verfahren zur Herstellung von Methylsteroiden
DE1543266A1 (de) Verfahren zur Herstellung von Steroiden der OEstranreihe
DE953343C (de) Verfahren zur Hydrolyse von Steroid-3-enaminen
DE1136331B (de) Verfahren zur Herstellung von 4-Chlor- bzw. 4-Brom í¸-3-Ketonen der Androstan- oder Pregnanreihe
DE1134987B (de) Verfahren zur Herstellung von 17ª‡-Acyloxy-6-methyl-16-methylen-pregna-4, 6-dien-3, 20-dionen
DE1134986B (de) Verfahren zur Herstellung von cyclischen 16 alpha, 17 alpha-Acetalen und -Ketalen der 6 alpha-Methylpregnanreihe.
DE1210811B (de) Verfahren zur Herstellung von delta 1,3,5(10)-3-Hydroxysteroidtrienen
DE1101415B (de) Verfahren zur Herstellung von 6ª‡-Methyl-17ª‡-acetoxy-4-pregnen-3, 20-dion
DE1216297B (de) Verfahren zur Herstellung von 19-Hydroxy-11-oxo-steroiden
DE1243682B (de) Verfahren zur Herstellung von therapeutisch wirksamen Steroidverbindungen
DE1161265B (de) Verfahren zur Herstellung von 3-Oxo-í¸-steroiden
DE1199262B (de) Verfahren zur Herstellung von 5alpha-Brom-6beta-hydroxysteroiden
DE1030339B (de) Verfahren zur Reduktion von a,/J-Epoxyketonen
DE1212966B (de) Verfahren zur Herstellung von 10beta-Acyloxy-19-nor-steroiden
DE1210817B (de) Verfahren zur Herstellung von 7-Methoxy-17alpha-methyl-testosteron bzw. -estern