DE1110159B - Verfahren zur Herstellung analeptisch wirksamer N-substituierter Aminonorcamphanderivate bzw. von deren Saeureadditionssalzen und quaternaeren Ammoniumverbindungen - Google Patents

Verfahren zur Herstellung analeptisch wirksamer N-substituierter Aminonorcamphanderivate bzw. von deren Saeureadditionssalzen und quaternaeren Ammoniumverbindungen

Info

Publication number
DE1110159B
DE1110159B DEM42332A DEM0042332A DE1110159B DE 1110159 B DE1110159 B DE 1110159B DE M42332 A DEM42332 A DE M42332A DE M0042332 A DEM0042332 A DE M0042332A DE 1110159 B DE1110159 B DE 1110159B
Authority
DE
Germany
Prior art keywords
heptane
ether
phenyl
reaction
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DEM42332A
Other languages
German (de)
English (en)
Inventor
Dipl-Chem Dr Jan Thesing
Dipl-Chem Dr Georg Seitz
Dr Med Rudolf Hotovy
Dr Med Siegmund Sommer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck KGaA
Original Assignee
E Merck AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DEM42332A priority Critical patent/DE1110159B/de
Application filed by E Merck AG filed Critical E Merck AG
Priority to CH779260A priority patent/CH385196A/de
Priority to BE593463A priority patent/BE593463A/fr
Priority to GB2631360A priority patent/GB913866A/en
Priority to SE743760A priority patent/SE302957B/xx
Priority to DEM46811A priority patent/DE1201338B/de
Priority to FR834659A priority patent/FR978M/fr
Publication of DE1110159B publication Critical patent/DE1110159B/de
Priority to CH942461A priority patent/CH419105A/de
Priority to FR873190A priority patent/FR25F/fr
Priority to GB35384/61A priority patent/GB968714A/en
Priority to US143578A priority patent/US3164601A/en
Priority to BE609074A priority patent/BE609074R/fr
Priority to SE10126/61A priority patent/SE310175B/xx
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DEM42332A 1959-08-01 1959-08-01 Verfahren zur Herstellung analeptisch wirksamer N-substituierter Aminonorcamphanderivate bzw. von deren Saeureadditionssalzen und quaternaeren Ammoniumverbindungen Pending DE1110159B (de)

Priority Applications (13)

Application Number Priority Date Filing Date Title
DEM42332A DE1110159B (de) 1959-08-01 1959-08-01 Verfahren zur Herstellung analeptisch wirksamer N-substituierter Aminonorcamphanderivate bzw. von deren Saeureadditionssalzen und quaternaeren Ammoniumverbindungen
CH779260A CH385196A (de) 1959-08-01 1960-07-08 Verfahren zur Herstellung analeptisch wirksamer N-substituierter Aminonorcamphanderivate
BE593463A BE593463A (fr) 1959-08-01 1960-07-27 Procédé de préparation de dérivés N-substitués d'amino-norcamphane à activité analeptique.
GB2631360A GB913866A (en) 1959-08-01 1960-07-28 Improvements in or relating to amino-norcamphane compounds
SE743760A SE302957B (es) 1959-08-01 1960-08-01
DEM46811A DE1201338B (de) 1959-08-01 1960-10-13 Verfahren zur Herstellung analeptisch wirksamer N-substituierter Aminobicyclo-heptanderivate bzw. von deren Saeureadditions-salzen und quaternaeren Ammonium-verbindungen
FR834659A FR978M (es) 1959-08-01 1960-10-24
CH942461A CH419105A (de) 1959-08-01 1961-08-11 Verfahren zur Herstellung analeptisch wirksamer N-substituierter Amino-norcamphanderivate bzw. von deren Säureadditionssalzen und quaternären Ammoniumverbindungen
FR873190A FR25F (fr) 1959-08-01 1961-09-14 Dérivés d'amino norcamphane n-substitués a action analeptique.
GB35384/61A GB968714A (en) 1959-08-01 1961-09-29 Analeptically active n-substituted amino-norcamphane derivatives and their addition salts with acids and their quaternary ammonium compounds
US143578A US3164601A (en) 1959-08-01 1961-10-09 Analeptically active n-substituted aminonorcamphane derivatives and their acid addition salts and quaternary ammonium compounds
BE609074A BE609074R (fr) 1959-08-01 1961-10-12 Procédé de préparation de dérivés N-substitués d'amino-norcamphane à activité analeptique
SE10126/61A SE310175B (es) 1959-08-01 1961-10-12

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEM42332A DE1110159B (de) 1959-08-01 1959-08-01 Verfahren zur Herstellung analeptisch wirksamer N-substituierter Aminonorcamphanderivate bzw. von deren Saeureadditionssalzen und quaternaeren Ammoniumverbindungen

Publications (1)

Publication Number Publication Date
DE1110159B true DE1110159B (de) 1961-07-06

Family

ID=7304304

Family Applications (1)

Application Number Title Priority Date Filing Date
DEM42332A Pending DE1110159B (de) 1959-08-01 1959-08-01 Verfahren zur Herstellung analeptisch wirksamer N-substituierter Aminonorcamphanderivate bzw. von deren Saeureadditionssalzen und quaternaeren Ammoniumverbindungen

Country Status (6)

Country Link
BE (1) BE593463A (es)
CH (1) CH385196A (es)
DE (1) DE1110159B (es)
FR (1) FR978M (es)
GB (1) GB913866A (es)
SE (1) SE302957B (es)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3164601A (en) * 1959-08-01 1965-01-05 Merck Ag E Analeptically active n-substituted aminonorcamphane derivatives and their acid addition salts and quaternary ammonium compounds
US3308160A (en) * 1963-06-26 1967-03-07 Du Pont 4-phenylbicyclo[2.2.2]octane-1-amines and salts thereof
US3341402A (en) * 1965-01-15 1967-09-12 Smith Kline French Lab Anti-viral composition and method
US3362878A (en) * 1966-08-01 1968-01-09 Du Pont Pharmaceutical compositions and methods utilizing substituted bicyclo[2.2.2]-octanes
DE2003744A1 (de) * 1969-02-06 1970-09-03 Colgate Palmolive Co In 3- und 4-Stellung disubstituierte 3-Amino-2-bicyclo[2,2,2]zu-octan-2-ole und Verfahren zu deren Herstellung
DE19835766C2 (de) * 1998-08-07 2003-07-03 Bosch Gmbh Robert Anordnung zum Beschalten eines elektrochemischen Sensors
US11840495B2 (en) 2020-12-23 2023-12-12 The Broad Institute, Inc. Compositions and methods related to di-substituted bicyclo[2.2.1] heptanamine-containing compounds

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1284421B (de) * 1962-06-09 1968-12-05 Knoll Ag Bicyclisch substituierte Aminoalkane und Verfahren zu ihrer Herstellung
DE1298527B (de) * 1962-06-09 1969-07-03 Knoll Ag Verfahren zur Herstellung bicyclisch substituierter Aminoalkane
US10662146B2 (en) 2015-09-15 2020-05-26 Praxis Bioresearch, LLC Prodrugs of fencamfamine

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3164601A (en) * 1959-08-01 1965-01-05 Merck Ag E Analeptically active n-substituted aminonorcamphane derivatives and their acid addition salts and quaternary ammonium compounds
US3308160A (en) * 1963-06-26 1967-03-07 Du Pont 4-phenylbicyclo[2.2.2]octane-1-amines and salts thereof
US3341402A (en) * 1965-01-15 1967-09-12 Smith Kline French Lab Anti-viral composition and method
US3362878A (en) * 1966-08-01 1968-01-09 Du Pont Pharmaceutical compositions and methods utilizing substituted bicyclo[2.2.2]-octanes
DE2003744A1 (de) * 1969-02-06 1970-09-03 Colgate Palmolive Co In 3- und 4-Stellung disubstituierte 3-Amino-2-bicyclo[2,2,2]zu-octan-2-ole und Verfahren zu deren Herstellung
DE19835766C2 (de) * 1998-08-07 2003-07-03 Bosch Gmbh Robert Anordnung zum Beschalten eines elektrochemischen Sensors
US11840495B2 (en) 2020-12-23 2023-12-12 The Broad Institute, Inc. Compositions and methods related to di-substituted bicyclo[2.2.1] heptanamine-containing compounds

Also Published As

Publication number Publication date
FR978M (es) 1961-12-04
CH385196A (de) 1964-12-15
GB913866A (en) 1962-12-28
SE302957B (es) 1968-08-12
BE593463A (fr) 1961-01-27

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