DE10161110A1 - Pharmazeutische Zusammensetzung zur ophthalmologischen und rhinologischen Anwendung - Google Patents
Pharmazeutische Zusammensetzung zur ophthalmologischen und rhinologischen AnwendungInfo
- Publication number
- DE10161110A1 DE10161110A1 DE10161110A DE10161110A DE10161110A1 DE 10161110 A1 DE10161110 A1 DE 10161110A1 DE 10161110 A DE10161110 A DE 10161110A DE 10161110 A DE10161110 A DE 10161110A DE 10161110 A1 DE10161110 A1 DE 10161110A1
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical composition
- eye
- weight
- hyaluronate
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 65
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 48
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 48
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 48
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims abstract description 46
- WCDDVEOXEIYWFB-VXORFPGASA-N (2s,3s,4r,5r,6r)-3-[(2s,3r,5s,6r)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O)[C@H](O)[C@H]1O WCDDVEOXEIYWFB-VXORFPGASA-N 0.000 claims abstract description 35
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- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical group [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 15
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10161110A DE10161110A1 (de) | 2001-12-12 | 2001-12-12 | Pharmazeutische Zusammensetzung zur ophthalmologischen und rhinologischen Anwendung |
| AT02794984T ATE300306T1 (de) | 2001-12-12 | 2002-12-11 | Pharmazeutische zusammensetzung zur ophtalmologischen und rhinologischen anwendung |
| EP02794984.1A EP1455803B2 (de) | 2001-12-12 | 2002-12-11 | Verwendung von panthenol und/oder panthothensäure und hyaluronsäure/und oder hyaluronat zur herstellung einer pharmazeutischen zusammensetzung zur ophtalmologischen anwendung |
| AU2002360895A AU2002360895A1 (en) | 2001-12-12 | 2002-12-11 | Pharmaceutical composition for use in ophthalmology and rhinology |
| PCT/DE2002/004527 WO2003049747A1 (de) | 2001-12-12 | 2002-12-11 | Pharmazeutische zusammensetzung zur ophtalmologischen und rhinologischen anwendung |
| CNB028248309A CN1310651C (zh) | 2001-12-12 | 2002-12-11 | 用于眼科和鼻科的药物组合物 |
| MXPA04005387A MXPA04005387A (es) | 2001-12-12 | 2002-12-11 | Composicion farmaceutica para uso en oftalmologia y rinologia. |
| US10/496,456 US20050164979A1 (en) | 2001-12-12 | 2002-12-11 | Pharmaceutical composition for ophthalmological and rhinological application |
| ES02794984.1T ES2244831T5 (es) | 2001-12-12 | 2002-12-11 | Uso de pantenol y/o ácido pantoténico y ácido hialurónico y/o hialuronato para la producción de una composición farmacéutica para aplicación oftalmológica |
| CA002468771A CA2468771C (en) | 2001-12-12 | 2002-12-11 | Pharmaceutical composition for use in ophthalmology and rhinology |
| DE50203788T DE50203788D1 (de) | 2001-12-12 | 2002-12-11 | Pharmazeutische zusammensetzung zur ophtalmologischen und rhinologischen anwendung |
| JP2003550796A JP3994089B2 (ja) | 2001-12-12 | 2002-12-11 | 眼科学および鼻科学における適用のための薬学的組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10161110A DE10161110A1 (de) | 2001-12-12 | 2001-12-12 | Pharmazeutische Zusammensetzung zur ophthalmologischen und rhinologischen Anwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE10161110A1 true DE10161110A1 (de) | 2003-06-26 |
Family
ID=7708986
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10161110A Ceased DE10161110A1 (de) | 2001-12-12 | 2001-12-12 | Pharmazeutische Zusammensetzung zur ophthalmologischen und rhinologischen Anwendung |
| DE50203788T Expired - Lifetime DE50203788D1 (de) | 2001-12-12 | 2002-12-11 | Pharmazeutische zusammensetzung zur ophtalmologischen und rhinologischen anwendung |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
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| DE50203788T Expired - Lifetime DE50203788D1 (de) | 2001-12-12 | 2002-12-11 | Pharmazeutische zusammensetzung zur ophtalmologischen und rhinologischen anwendung |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20050164979A1 (enExample) |
| EP (1) | EP1455803B2 (enExample) |
| JP (1) | JP3994089B2 (enExample) |
| CN (1) | CN1310651C (enExample) |
| AT (1) | ATE300306T1 (enExample) |
| AU (1) | AU2002360895A1 (enExample) |
| CA (1) | CA2468771C (enExample) |
| DE (2) | DE10161110A1 (enExample) |
| ES (1) | ES2244831T5 (enExample) |
| MX (1) | MXPA04005387A (enExample) |
| WO (1) | WO2003049747A1 (enExample) |
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| DE102005055275A1 (de) * | 2005-11-17 | 2007-05-24 | Ursapharm Arzneimittel Gmbh & Co. Kg | Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung |
| DE102017117987A1 (de) * | 2017-07-31 | 2019-01-31 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh | Neue Zusammensetzung für die nasale Applikation |
| EP2985027B1 (en) | 2014-08-16 | 2021-03-31 | Church & Dwight Co., Inc. | Nasal composition comprising mixture of hyaluronic acids and saline solution |
| EP2985019B1 (en) | 2014-08-16 | 2021-10-20 | Church & Dwight Co., Inc. | Nasal composition having anti-viral properties |
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| DE20318634U1 (de) | 2003-11-13 | 2004-02-26 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh | Pharmazeutische Zusammensetzung zur Behandlung von Rhinitiden |
| DE102004002001A1 (de) * | 2004-01-14 | 2005-08-11 | Reinmüller, Johannes, Dr.med. | Mittel zur Behandlung von entzündlichen Erkrankungen |
| CN1285382C (zh) * | 2004-12-20 | 2006-11-22 | 凌沛学 | 含海藻糖和玻璃酸的鼻腔用药传递系统及其制备方法 |
| MX2009000885A (es) | 2006-07-25 | 2009-02-05 | Osmotica Corp | Soluciones oftalmicas. |
| WO2008068866A1 (en) * | 2006-11-30 | 2008-06-12 | Menicon Co., Ltd. | Ophthalmic composition |
| KR100927579B1 (ko) * | 2006-12-13 | 2009-11-23 | 주식회사 엘지생명과학 | 히아루론산 및/또는 그것의 염을 함유하는 아토피성피부염의 개선 및 치료를 위한 조성물 |
| FR2919185B1 (fr) | 2007-07-23 | 2010-09-10 | Ard Sa | Utilisation d'acide hyaluronique pour la preparation de compositions destinees a l'amelioration notamment de l'etat des muqueuses |
| DE202008016517U1 (de) * | 2008-12-12 | 2009-03-05 | Ratiopharm Gmbh | Wässrige Zusammensetzung enthaltend Dexpanthenol und Natriumchlorid |
| US9473792B2 (en) * | 2009-11-06 | 2016-10-18 | Texas Instruments Incorporated | Method and system to improve the performance of a video encoder |
| FR2962044B1 (fr) * | 2010-04-21 | 2013-02-22 | Horus Pharma | Emulsion lacrymimetique |
| JP2013534527A (ja) * | 2010-07-02 | 2013-09-05 | ブライエン ホールデン ビジョン インスティテュート | コンタクトレンズ乳頭結膜炎及びアレルギー性眼疾患の予防及び処置のための組成物 |
| DE202010012255U1 (de) * | 2010-09-07 | 2010-11-18 | Krewel Meuselbach Gmbh | Nasenspray |
| WO2012119261A1 (en) * | 2011-03-10 | 2012-09-13 | Biocia Inc. | Enhanced artificial mucus composition comprising hyaluronan for the treatment of rhinitis |
| CN102579478A (zh) * | 2012-03-30 | 2012-07-18 | 济南康众医药科技开发有限公司 | 玻璃酸钠在制备药物中的应用 |
| DE102012011447B4 (de) | 2012-05-14 | 2022-11-24 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh | Verwendung von Pantothenol oder Pantothensäure in einem Kombinationstherapeutikum für die Behandlung von Rhinitis zur Verringerung der systemischen Resorption imidazolinbasierter alpha-Sympathomimetika |
| EP2664330A1 (de) * | 2012-05-15 | 2013-11-20 | F. Holzer GmbH | Zusammensetzung und Arzneimittel enthaltend Omega-3-Fettsäuren sowie einen Glucosaminoglucan |
| CN102989045B (zh) * | 2012-11-12 | 2015-02-25 | 广州共禾医药科技有限公司 | 生物相容的水性组合物及其用途 |
| CA2945604C (en) * | 2014-08-08 | 2022-08-23 | Shenzhen Hightide Biopharmaceutical, Ltd. | Liquid formulation compositions, medicament delivery devices, and methods of preparation and use thereof |
| ES2827426T3 (es) | 2015-03-26 | 2021-05-21 | Dmg Italia Srl | Composición oftálmica para la protección corneal |
| DE102016203696A1 (de) * | 2016-03-07 | 2017-09-07 | Ursapharm Arzneimittel Gmbh | Ophthalmologische Zusammensetzung |
| DE102016204472A1 (de) * | 2016-03-17 | 2017-09-21 | Ursapharm Arzneimittel Gmbh | Kit zur kosmetischen Behandlung des Auges und der Haut und Kosmetikum zur Anwendung am Auge und auf der Haut |
| TWI609957B (zh) * | 2016-06-27 | 2018-01-01 | 晶碩光學股份有限公司 | 用以處理隱形眼鏡之溶液及隱形眼鏡的包裝系統 |
| JP7044467B2 (ja) * | 2017-01-16 | 2022-03-30 | ロート製薬株式会社 | 眼科組成物 |
| CN107260657B (zh) * | 2017-08-03 | 2019-02-05 | 广东莱恩医药研究院有限公司 | 一种缓释型连翘苷滴眼液及其制备方法 |
| ES2972897T3 (es) * | 2017-08-10 | 2024-06-17 | Elixir Ilac Arastirma Ve Gelistirme A S | Composiciones descongestionantes nasales que comprenden mentol, dexpantenol e hialuronato de sodio |
| WO2019202017A1 (en) * | 2018-04-18 | 2019-10-24 | i.com medical GmbH | High molecular weight hyaluronic acid for treatment and prevention of severe ocular surface disease |
| EP3781116A1 (en) * | 2018-04-18 | 2021-02-24 | i.com Medical GmbH | High molecular weight hyaluronic acid for enhancing epithelial survival and reconstitution of body surfaces |
| US11576926B2 (en) * | 2018-09-12 | 2023-02-14 | Neilos S.r.l. | Composition for use in the prevention and/or treatment of epistaxis |
| US12268706B2 (en) | 2019-01-31 | 2025-04-08 | i.com medical GmbH | Hyaluronic acid for relief of idiopathic ocular pain |
| EP3827818A1 (en) * | 2019-11-26 | 2021-06-02 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Ophthalmic composition |
| CN112870216A (zh) * | 2021-01-29 | 2021-06-01 | 张宽才 | 一种药物组合物及制剂和用途 |
| EP4039248A1 (en) * | 2021-02-04 | 2022-08-10 | Warszawskie Zaklady Farmaceutyczne Polfa S.A. | Ophthalmic composition |
| FR3151481A1 (fr) * | 2023-07-28 | 2025-01-31 | Horus Pharma | Emulsion de type huile dans eau comprenant de l’acide hyaluronique et du dexpanthenol |
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-
2001
- 2001-12-12 DE DE10161110A patent/DE10161110A1/de not_active Ceased
-
2002
- 2002-12-11 AU AU2002360895A patent/AU2002360895A1/en not_active Abandoned
- 2002-12-11 MX MXPA04005387A patent/MXPA04005387A/es active IP Right Grant
- 2002-12-11 WO PCT/DE2002/004527 patent/WO2003049747A1/de not_active Ceased
- 2002-12-11 AT AT02794984T patent/ATE300306T1/de active
- 2002-12-11 JP JP2003550796A patent/JP3994089B2/ja not_active Expired - Lifetime
- 2002-12-11 US US10/496,456 patent/US20050164979A1/en not_active Abandoned
- 2002-12-11 CN CNB028248309A patent/CN1310651C/zh not_active Expired - Lifetime
- 2002-12-11 EP EP02794984.1A patent/EP1455803B2/de not_active Expired - Lifetime
- 2002-12-11 DE DE50203788T patent/DE50203788D1/de not_active Expired - Lifetime
- 2002-12-11 CA CA002468771A patent/CA2468771C/en not_active Expired - Lifetime
- 2002-12-11 ES ES02794984.1T patent/ES2244831T5/es not_active Expired - Lifetime
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| DE3832401A1 (de) * | 1988-09-23 | 1990-03-29 | Cassella Ag | Pharmazeutische zubereitung zur behandlung entzuendeter nasenschleimhaeute |
| DE19517251A1 (de) * | 1995-05-11 | 1996-11-14 | Klosterfrau Mcm Vetrieb Gmbh | Verwendung von Dexpanthenol zur Behandlung trockener Nasenschleimhäute |
| DE19923829A1 (de) * | 1999-05-17 | 2000-11-23 | Ulrich Kluegel | Hyaluronat-Wirkstoff-Wasser-Komplex, dessen Herstellung und Verwendung |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005055275A1 (de) * | 2005-11-17 | 2007-05-24 | Ursapharm Arzneimittel Gmbh & Co. Kg | Phosphatfreie pharmazeutische Zusammensetzung sowie deren Verwendung |
| US8648057B2 (en) | 2005-11-17 | 2014-02-11 | Ursapharm Arzneimittel Gmbh & Co. Kg | Pharmaceutical composition free from dexpanthenol, calcium ions, and phosphate and use of calcium chelating agent and ophthalmologically compatible viscosity regulator |
| EP2985027B1 (en) | 2014-08-16 | 2021-03-31 | Church & Dwight Co., Inc. | Nasal composition comprising mixture of hyaluronic acids and saline solution |
| EP2985019B1 (en) | 2014-08-16 | 2021-10-20 | Church & Dwight Co., Inc. | Nasal composition having anti-viral properties |
| DE102017117987A1 (de) * | 2017-07-31 | 2019-01-31 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh | Neue Zusammensetzung für die nasale Applikation |
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA04005387A (es) | 2005-03-23 |
| CN1602198A (zh) | 2005-03-30 |
| ES2244831T3 (es) | 2005-12-16 |
| JP3994089B2 (ja) | 2007-10-17 |
| WO2003049747A8 (de) | 2003-10-02 |
| CA2468771C (en) | 2007-01-30 |
| CA2468771A1 (en) | 2003-06-19 |
| DE50203788D1 (de) | 2005-09-01 |
| EP1455803A1 (de) | 2004-09-15 |
| US20050164979A1 (en) | 2005-07-28 |
| EP1455803B2 (de) | 2016-03-23 |
| ATE300306T1 (de) | 2005-08-15 |
| JP2006501133A (ja) | 2006-01-12 |
| ES2244831T5 (es) | 2016-05-10 |
| EP1455803B1 (de) | 2005-07-27 |
| CN1310651C (zh) | 2007-04-18 |
| AU2002360895A1 (en) | 2003-06-23 |
| WO2003049747A1 (de) | 2003-06-19 |
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