DD296930A5 - Dihydro-pyrimido-thiazin-derivate und verfahren zu ihrer herstellung - Google Patents

Dihydro-pyrimido-thiazin-derivate und verfahren zu ihrer herstellung Download PDF

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Publication number
DD296930A5
DD296930A5 DD90342877A DD34287790A DD296930A5 DD 296930 A5 DD296930 A5 DD 296930A5 DD 90342877 A DD90342877 A DD 90342877A DD 34287790 A DD34287790 A DD 34287790A DD 296930 A5 DD296930 A5 DD 296930A5
Authority
DD
German Democratic Republic
Prior art keywords
general formula
mol
methyl
alkyl
dihydro
Prior art date
Application number
DD90342877A
Other languages
German (de)
English (en)
Inventor
Daniel Bozsing
Pal Benko
Lujzy Petocz
Nee Hegedues Maria Szecsey
Peter Toempe
Gabor Gigler
Istvan Gacsaly
Istvan Gyertyan
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU365989A external-priority patent/HU205123B/hu
Application filed by ������@������������k�� filed Critical ������@������������k��
Publication of DD296930A5 publication Critical patent/DD296930A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Luminescent Compositions (AREA)
DD90342877A 1989-07-19 1990-07-18 Dihydro-pyrimido-thiazin-derivate und verfahren zu ihrer herstellung DD296930A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU893658A HU203878B (en) 1989-07-19 1989-07-19 Process for producing tetrahydro-pyrimidine carboxylic acid derivatives
HU365989A HU205123B (en) 1989-07-19 1989-07-19 Process for producing dihydropyrimidino thiazine derivatives and pharmaceutical compositions comprising same

Publications (1)

Publication Number Publication Date
DD296930A5 true DD296930A5 (de) 1991-12-19

Family

ID=26317670

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90342877A DD296930A5 (de) 1989-07-19 1990-07-18 Dihydro-pyrimido-thiazin-derivate und verfahren zu ihrer herstellung

Country Status (21)

Country Link
US (1) US5071849A (el)
EP (1) EP0409223A3 (el)
JP (1) JPH03148284A (el)
KR (1) KR940006637B1 (el)
AT (1) AT399879B (el)
BE (1) BE1004489A3 (el)
BG (1) BG60209B2 (el)
CA (1) CA2021556A1 (el)
CZ (1) CZ280445B6 (el)
DD (1) DD296930A5 (el)
ES (1) ES2027492A6 (el)
FR (1) FR2649981B1 (el)
GB (1) GB2234508B (el)
GR (1) GR910300031T1 (el)
HU (1) HU203878B (el)
IL (1) IL95091A (el)
IT (1) IT1249212B (el)
PL (1) PL163653B1 (el)
RU (1) RU2022965C1 (el)
YU (1) YU47949B (el)
ZA (1) ZA905456B (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5677300A (en) * 1993-03-29 1997-10-14 The Green Cross Corporation Pyridothiazineacetic acid compound, production thereof and use thereof
IL132137A0 (en) * 1997-04-02 2001-03-19 Natural Drug Sciences Llc Biologically active substance on the basis of tetracyclic nitrogen heterocycles of pyrimidine row
WO2002066443A2 (en) * 2001-02-21 2002-08-29 Ono Pharmaceutical Co., Ltd. 2-thioxo-1,2,3,4-tetrahydropyrimidine derivatives
CN104844628B (zh) * 2015-04-16 2017-01-18 石家庄学院 2H,6H‑嘧啶并[2,1‑b][1,3]噻嗪类衍生物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1275804A (en) * 1969-07-03 1972-05-24 Seperic Improvements in or relating to new sulphur containing derivatives of pyrimidine, their preparation and their applications
US4753946A (en) * 1987-04-08 1988-06-28 E. R. Squibb & Sons, Inc. Pyrimidinecarboxylic acid derivatives

Also Published As

Publication number Publication date
EP0409223A3 (en) 1991-11-21
AT399879B (de) 1995-08-25
PL163653B1 (pl) 1994-04-29
IL95091A0 (en) 1991-06-10
GB2234508B (en) 1993-01-06
BG60209B2 (en) 1993-12-30
RU2022965C1 (ru) 1994-11-15
US5071849A (en) 1991-12-10
GB9015831D0 (en) 1990-09-05
KR940006637B1 (ko) 1994-07-23
EP0409223A2 (de) 1991-01-23
YU47949B (sh) 1996-07-24
ATA152890A (de) 1994-12-15
FR2649981A1 (fr) 1991-01-25
IT9020982A0 (it) 1990-07-19
CZ357190A3 (en) 1995-10-18
ES2027492A6 (es) 1992-06-01
GR910300031T1 (en) 1991-11-15
CA2021556A1 (en) 1991-01-20
IT1249212B (it) 1995-02-20
JPH03148284A (ja) 1991-06-25
HUT54352A (en) 1991-02-28
BE1004489A3 (fr) 1992-12-01
ZA905456B (en) 1994-08-09
IL95091A (en) 1994-11-11
IT9020982A1 (it) 1992-01-19
KR910002875A (ko) 1991-02-26
YU141290A (sh) 1992-12-21
HU203878B (en) 1991-10-28
PL286086A1 (en) 1991-07-29
FR2649981B1 (fr) 1993-07-30
CZ280445B6 (cs) 1996-01-17
GB2234508A (en) 1991-02-06

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