DD272851A5 - Verfahren zum herstellen von 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazol-dihydrochlorid-trihydrat - Google Patents

Verfahren zum herstellen von 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazol-dihydrochlorid-trihydrat Download PDF

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Publication number
DD272851A5
DD272851A5 DD87318777A DD31877787A DD272851A5 DD 272851 A5 DD272851 A5 DD 272851A5 DD 87318777 A DD87318777 A DD 87318777A DD 31877787 A DD31877787 A DD 31877787A DD 272851 A5 DD272851 A5 DD 272851A5
Authority
DD
German Democratic Republic
Prior art keywords
methyl
guanidino
imidazolyl
pentyl
trihydrate
Prior art date
Application number
DD87318777A
Other languages
German (de)
English (en)
Inventor
Douglas J M Allen
Berkeley W Cue Jr
Paul D Hill
William M Snyder
Stanley W Walinsky
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@���Kk�� filed Critical ������@���Kk��
Publication of DD272851A5 publication Critical patent/DD272851A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/24—Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
    • C07C335/28—Y being a hetero atom, e.g. thiobiuret

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DD87318777A 1986-10-29 1987-10-27 Verfahren zum herstellen von 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazol-dihydrochlorid-trihydrat DD272851A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1986/002307 WO1988003140A1 (en) 1986-10-29 1986-10-29 Crystalline 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole dihydrochloride trihydrate

Publications (1)

Publication Number Publication Date
DD272851A5 true DD272851A5 (de) 1989-10-25

Family

ID=22195693

Family Applications (2)

Application Number Title Priority Date Filing Date
DD87318777A DD272851A5 (de) 1986-10-29 1987-10-27 Verfahren zum herstellen von 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazol-dihydrochlorid-trihydrat
DD87308315A DD262659A5 (de) 1986-10-29 1987-10-27 Verfahren zum herstellen von 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazol und seines kristallinen dihydrochlorid-trihydrats

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD87308315A DD262659A5 (de) 1986-10-29 1987-10-27 Verfahren zum herstellen von 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazol und seines kristallinen dihydrochlorid-trihydrats

Country Status (11)

Country Link
US (1) US4997949A (zh)
JP (1) JPS63122680A (zh)
AU (1) AU579775B2 (zh)
CA (1) CA1313378C (zh)
DD (2) DD272851A5 (zh)
FI (1) FI89918C (zh)
NO (1) NO170417C (zh)
PH (1) PH23922A (zh)
RU (1) RU1779252C (zh)
WO (1) WO1988003140A1 (zh)
ZA (1) ZA878083B (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387597A (en) * 1991-02-25 1995-02-07 Pfizer Inc. Hemiphosphate hemihydrate of 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole
NO329085B1 (no) * 2008-01-31 2010-08-16 Sorbwater Technology As Fremgangsmate og apparat for separasjon av fluidfaser, samt anvendelser derav

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN163170B (zh) * 1980-10-14 1988-08-20 Pfizer
US4560690A (en) * 1984-04-30 1985-12-24 Pfizer Inc. 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents
JPS6191122A (ja) * 1984-10-11 1986-05-09 フアイザー・インコーポレーテツド ２―グアニジノ―４―（２―メチル―４―イミダゾリル）チアゾール類からなる慢性関節リウマチ治療用組成物
US4632993A (en) * 1984-10-11 1986-12-30 Pfizer Inc. Process for making 2-guanidino-4-(2-methyl-4-imidazolyl) thiazole dihydrobromide

Also Published As

Publication number Publication date
CA1313378C (en) 1993-02-02
AU579775B2 (en) 1988-12-08
DD262659A5 (de) 1988-12-07
FI89918B (fi) 1993-08-31
JPH0513952B2 (zh) 1993-02-23
FI892034A0 (fi) 1989-04-28
AU8042887A (en) 1988-05-05
ZA878083B (en) 1989-06-28
NO882861L (no) 1988-06-28
NO170417C (no) 1992-10-14
FI89918C (fi) 1993-12-10
RU1779252C (ru) 1992-11-30
WO1988003140A1 (en) 1988-05-05
US4997949A (en) 1991-03-05
NO882861D0 (no) 1988-06-28
FI892034A (fi) 1989-04-28
JPS63122680A (ja) 1988-05-26
NO170417B (no) 1992-07-06
PH23922A (en) 1990-01-23

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