FI892034A - Kristallint 2-(1-pentyl-3-guanidino)-4-(2-metyl-4-imidazolyl) tiazoldihydrokloridtrihydrat. - Google Patents

Kristallint 2-(1-pentyl-3-guanidino)-4-(2-metyl-4-imidazolyl) tiazoldihydrokloridtrihydrat. Download PDF

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Publication number
FI892034A
FI892034A FI892034A FI892034A FI892034A FI 892034 A FI892034 A FI 892034A FI 892034 A FI892034 A FI 892034A FI 892034 A FI892034 A FI 892034A FI 892034 A FI892034 A FI 892034A
Authority
FI
Finland
Prior art keywords
thiazolehydrochloride
guanidino
trihydrate
imidazolyl
pentyl
Prior art date
Application number
FI892034A
Other languages
English (en)
Other versions
FI89918C (fi
FI892034A0 (fi
FI89918B (fi
Inventor
Douglas John Meldrum Allen
Jr Berkeley Wendell Cue
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI892034A publication Critical patent/FI892034A/fi
Publication of FI892034A0 publication Critical patent/FI892034A0/fi
Application granted granted Critical
Publication of FI89918B publication Critical patent/FI89918B/fi
Publication of FI89918C publication Critical patent/FI89918C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/24—Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
    • C07C335/28—Y being a hetero atom, e.g. thiobiuret

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
FI892034A 1986-10-29 1989-04-28 Foerfarande foer framstaellning av ett terapeutiskt anvaendbart kristallint 2-(1-pentyl-3-guanidino)-4-(2-metyl-4-imidazolyl)tiazoldihydrokloridtrihydrat FI89918C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1986/002307 WO1988003140A1 (en) 1986-10-29 1986-10-29 Crystalline 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole dihydrochloride trihydrate
US8602307 1986-10-29

Publications (4)

Publication Number Publication Date
FI892034A true FI892034A (fi) 1989-04-28
FI892034A0 FI892034A0 (fi) 1989-04-28
FI89918B FI89918B (fi) 1993-08-31
FI89918C FI89918C (fi) 1993-12-10

Family

ID=22195693

Family Applications (1)

Application Number Title Priority Date Filing Date
FI892034A FI89918C (fi) 1986-10-29 1989-04-28 Foerfarande foer framstaellning av ett terapeutiskt anvaendbart kristallint 2-(1-pentyl-3-guanidino)-4-(2-metyl-4-imidazolyl)tiazoldihydrokloridtrihydrat

Country Status (11)

Country Link
US (1) US4997949A (fi)
JP (1) JPS63122680A (fi)
AU (1) AU579775B2 (fi)
CA (1) CA1313378C (fi)
DD (2) DD262659A5 (fi)
FI (1) FI89918C (fi)
NO (1) NO170417C (fi)
PH (1) PH23922A (fi)
RU (1) RU1779252C (fi)
WO (1) WO1988003140A1 (fi)
ZA (1) ZA878083B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5387597A (en) * 1991-02-25 1995-02-07 Pfizer Inc. Hemiphosphate hemihydrate of 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole
NO329085B1 (no) * 2008-01-31 2010-08-16 Sorbwater Technology As Fremgangsmate og apparat for separasjon av fluidfaser, samt anvendelser derav

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN163170B (fi) * 1980-10-14 1988-08-20 Pfizer
US4560690A (en) * 1984-04-30 1985-12-24 Pfizer Inc. 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents
US4632993A (en) * 1984-10-11 1986-12-30 Pfizer Inc. Process for making 2-guanidino-4-(2-methyl-4-imidazolyl) thiazole dihydrobromide
JPS6191122A (ja) * 1984-10-11 1986-05-09 フアイザー・インコーポレーテツド ２―グアニジノ―４―（２―メチル―４―イミダゾリル）チアゾール類からなる慢性関節リウマチ治療用組成物

Also Published As

Publication number Publication date
FI89918C (fi) 1993-12-10
NO882861L (no) 1988-06-28
AU579775B2 (en) 1988-12-08
AU8042887A (en) 1988-05-05
FI892034A0 (fi) 1989-04-28
CA1313378C (en) 1993-02-02
DD272851A5 (de) 1989-10-25
NO882861D0 (no) 1988-06-28
NO170417C (no) 1992-10-14
RU1779252C (ru) 1992-11-30
JPH0513952B2 (fi) 1993-02-23
ZA878083B (en) 1989-06-28
US4997949A (en) 1991-03-05
NO170417B (no) 1992-07-06
WO1988003140A1 (en) 1988-05-05
FI89918B (fi) 1993-08-31
JPS63122680A (ja) 1988-05-26
DD262659A5 (de) 1988-12-07
PH23922A (en) 1990-01-23

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed
MM Patent lapsed

Owner name: PFIZER INC.