DD251144A5 - Verfahren zur herstellung von steroidverbindungen - Google Patents

Verfahren zur herstellung von steroidverbindungen Download PDF

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Publication number
DD251144A5
DD251144A5 DD84261867A DD26186784A DD251144A5 DD 251144 A5 DD251144 A5 DD 251144A5 DD 84261867 A DD84261867 A DD 84261867A DD 26186784 A DD26186784 A DD 26186784A DD 251144 A5 DD251144 A5 DD 251144A5
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DD
German Democratic Republic
Prior art keywords
formula
compound
group
hydroxyl
acid
Prior art date
Application number
DD84261867A
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German (de)
English (en)
Inventor
Juergen Grob
Jaroslav Kalvoda
Original Assignee
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Publication of DD251144A5 publication Critical patent/DD251144A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001—Lactones
    • C07J21/003—Lactones at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/008—Ketals at position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/007—3 membered carbocyclic rings in position 6-7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C07J71/0015—Oxiranes at position 9(11)

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DD84261867A 1983-04-13 1984-04-11 Verfahren zur herstellung von steroidverbindungen DD251144A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH198183 1983-04-13

Publications (1)

Publication Number Publication Date
DD251144A5 true DD251144A5 (de) 1987-11-04

Family

ID=4223123

Family Applications (2)

Application Number Title Priority Date Filing Date
DD84276211A DD233375A5 (de) 1983-04-13 1984-04-11 Verfahren zur herstellung von steroidverbindungen
DD84261867A DD251144A5 (de) 1983-04-13 1984-04-11 Verfahren zur herstellung von steroidverbindungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DD84276211A DD233375A5 (de) 1983-04-13 1984-04-11 Verfahren zur herstellung von steroidverbindungen

Country Status (23)

Country Link
US (1) US4559332A (fi)
EP (1) EP0122232B1 (fi)
JP (1) JPS59231100A (fi)
AR (4) AR241918A1 (fi)
AT (1) ATE39256T1 (fi)
AU (1) AU565017B2 (fi)
CA (1) CA1220781A (fi)
DD (2) DD233375A5 (fi)
DE (2) DE3475622D1 (fi)
DK (1) DK163988C (fi)
ES (4) ES531517A0 (fi)
FI (1) FI77669C (fi)
GR (1) GR81834B (fi)
HU (1) HU191406B (fi)
IE (1) IE57541B1 (fi)
IL (1) IL71504A (fi)
LU (1) LU91072I2 (fi)
NL (1) NL300144I2 (fi)
NO (1) NO159800C (fi)
NZ (1) NZ207826A (fi)
PH (1) PH19997A (fi)
PT (1) PT78413B (fi)
ZA (1) ZA842710B (fi)

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* Cited by examiner, † Cited by third party
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FI77669B (fi) 1988-12-30
ATE39256T1 (de) 1988-12-15
AR241918A1 (es) 1993-01-29
LU91072I2 (fr) 2004-04-07
GR81834B (fi) 1984-12-12
DD233375A5 (de) 1986-02-26
HU191406B (en) 1987-02-27
DK163988B (da) 1992-04-27
FI841400A0 (fi) 1984-04-09
ES544768A0 (es) 1987-05-01
DE122004000012I1 (de) 2012-05-16
ZA842710B (en) 1984-11-28
JPS59231100A (ja) 1984-12-25
CA1220781A (en) 1987-04-21
IL71504A (en) 1987-07-31
DE122004000012I2 (de) 2006-06-08
ES8705461A1 (es) 1987-05-01
AR242221A1 (es) 1993-03-31
AU565017B2 (en) 1987-09-03
ES8602846A1 (es) 1985-12-01
NL300144I1 (nl) 2004-06-01
PT78413A (en) 1984-05-01
DK163988C (da) 1992-09-21
FI77669C (fi) 1989-04-10
DK189484D0 (da) 1984-04-12
JPH0212479B2 (fi) 1990-03-20
AR242222A1 (es) 1993-03-31
ES544770A0 (es) 1987-05-01
IE840906L (en) 1984-10-13
NO159800B (no) 1988-10-31
PH19997A (en) 1986-08-28
PT78413B (en) 1986-08-22
IL71504A0 (en) 1984-07-31
NO841465L (no) 1984-10-15
ES544769A0 (es) 1987-05-01
FI841400A (fi) 1984-10-14
NO159800C (no) 1989-02-08
EP0122232B1 (de) 1988-12-14
ES8705460A1 (es) 1987-05-01
US4559332A (en) 1985-12-17
ES531517A0 (es) 1985-12-01
DK189484A (da) 1984-10-14
ES8705459A1 (es) 1987-05-01
NZ207826A (en) 1986-07-11
DE3475622D1 (en) 1989-01-19
NL300144I2 (nl) 2004-06-01
AR242223A1 (es) 1993-03-31
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EP0122232A1 (de) 1984-10-17
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