ATE330633T1 - Epoxy-steroidaler aldosteronantagonist und beta- adrenergischer antagonist-kombinationstherapie zur behandlung von kongestivem herzversagen - Google Patents
Epoxy-steroidaler aldosteronantagonist und beta- adrenergischer antagonist-kombinationstherapie zur behandlung von kongestivem herzversagenInfo
- Publication number
- ATE330633T1 ATE330633T1 AT01957290T AT01957290T ATE330633T1 AT E330633 T1 ATE330633 T1 AT E330633T1 AT 01957290 T AT01957290 T AT 01957290T AT 01957290 T AT01957290 T AT 01957290T AT E330633 T1 ATE330633 T1 AT E330633T1
- Authority
- AT
- Austria
- Prior art keywords
- beta
- epoxy
- antagonist
- combination therapy
- adrenergic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22136500P | 2000-07-27 | 2000-07-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE330633T1 true ATE330633T1 (de) | 2006-07-15 |
Family
ID=22827509
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01957290T ATE330633T1 (de) | 2000-07-27 | 2001-07-27 | Epoxy-steroidaler aldosteronantagonist und beta- adrenergischer antagonist-kombinationstherapie zur behandlung von kongestivem herzversagen |
Country Status (11)
Country | Link |
---|---|
US (3) | US20020123485A1 (de) |
EP (1) | EP1303306B1 (de) |
JP (1) | JP2004511435A (de) |
AT (1) | ATE330633T1 (de) |
AU (2) | AU2001279050B2 (de) |
CA (1) | CA2415789A1 (de) |
DE (1) | DE60120982T2 (de) |
DK (1) | DK1303306T3 (de) |
ES (1) | ES2265437T3 (de) |
PT (1) | PT1303306E (de) |
WO (1) | WO2002009760A2 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003049745A1 (en) * | 2001-12-12 | 2003-06-19 | Pharmacia Corporation | Method of treating ophthalmic disorders with epoxy-steroidal aldosterone receptor antagonists |
JP2005519918A (ja) * | 2002-01-30 | 2005-07-07 | ファルマシア・コーポレーション | 病因性状態を予防または治療するためのアルドステロン受容体拮抗剤およびα−アドレナリン作用変調剤の組み合わせ治療 |
MXPA04009033A (es) * | 2002-03-18 | 2005-01-25 | Pharmacia Corp | Combinacion de un antagonista de receptor de aldosterona y acido nicotinico o un derivado de acido nicotinico. |
US6967194B1 (en) * | 2002-09-18 | 2005-11-22 | Susan Matsuo | Bio-identical hormones and method of use |
US20040229901A1 (en) * | 2003-02-24 | 2004-11-18 | Lauren Otsuki | Method of treatment of disease using an adenosine A1 receptor antagonist |
US20040266743A1 (en) * | 2003-05-09 | 2004-12-30 | Pharmacia Corporation | Combination of an aldosterone receptor antagonist and a renin inhibitor |
JP2007528400A (ja) | 2004-03-09 | 2007-10-11 | エラン ファーマシューティカルズ,インコーポレイテッド | 置換ヒドロキシエチルアミン系のアスパラギン酸プロテアーゼ阻害薬 |
US7803838B2 (en) | 2004-06-04 | 2010-09-28 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
US7838552B2 (en) | 2004-06-04 | 2010-11-23 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
DE102004035322A1 (de) * | 2004-07-21 | 2006-02-16 | Universität des Saarlandes | Selektive Hemmstoffe humaner Corticoidsynthasen |
CN104644627A (zh) | 2004-09-14 | 2015-05-27 | 科罗拉多大学董事会 | 基于基因靶向使用布新洛尔的治疗方法 |
US9271963B2 (en) * | 2005-03-03 | 2016-03-01 | Universitat Des Saarlandes | Selective inhibitors of human corticosteroid synthases |
WO2007047305A1 (en) | 2005-10-12 | 2007-04-26 | Elan Pharmaceuticals, Inc. | Methods of treating amyloidosis using cyclopropyl derivative aspartyl protease inhibitors |
DE102008022221A1 (de) | 2008-05-06 | 2009-11-12 | Universität des Saarlandes | Inhibitoren der humanen Aldosteronsynthase CYP11B2 |
US8541404B2 (en) * | 2009-11-09 | 2013-09-24 | Elexopharm Gmbh | Inhibitors of the human aldosterone synthase CYP11B2 |
PE20190446A1 (es) * | 2016-06-22 | 2019-03-29 | Univ Vanderbilt | Moduladores alostericos positivos del receptor muscarinico de acetilcolina m4 |
US11008335B2 (en) | 2016-11-07 | 2021-05-18 | Vanderbilt University | Positive allosteric modulators of the muscarinic acetylcholine receptor M4 |
JP7099725B2 (ja) | 2016-11-07 | 2022-07-12 | ヴァンダービルト ユニヴァーシティ | ムスカリン性アセチルコリンレセプターm4のポジティブアロステリック調節因子 |
US10927126B2 (en) | 2016-11-07 | 2021-02-23 | Vanderbilt University | Positive allosteric modulators of the muscarinic acetylcholine receptor M4 |
TW201930311A (zh) | 2017-12-05 | 2019-08-01 | 泛德比爾特大學 | 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑 |
CN111406058A (zh) | 2017-12-05 | 2020-07-10 | 范德比尔特大学 | 毒蕈碱型乙酰胆碱受体m4的正向别构调节剂 |
WO2023060245A1 (en) * | 2021-10-08 | 2023-04-13 | The United States Government As Represented By The Department Of Veterans Affairs | Methods for predicting drug responsiveness in heart failure subjects |
Family Cites Families (24)
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ZA6808345B (en) * | 1967-12-22 | May & Baker Ltd | Benzene derivatives | |
US3641152A (en) * | 1968-09-23 | 1972-02-08 | Warner Lambert Pharmaceutical | 3 4-dihydronaphthalenoneoxy-2-hydroxy-propylamines |
US4012444A (en) * | 1969-07-08 | 1977-03-15 | Allen & Hanburys Limited | 5-[1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl] salicylamide and physiologically acceptable acid addition salts thereof |
US4340541A (en) * | 1975-08-15 | 1982-07-20 | Sandoz Ltd. | 4-(2-Benzoyloxy-3-tert.-butylaminopropoxy-2-methyl indole |
FR2330383A1 (fr) * | 1975-11-06 | 1977-06-03 | Synthelabo | Nouveaux ethers de phenols substitues, leurs sels, leur preparation et les medicaments qui les renferment |
US4387103A (en) * | 1980-11-28 | 1983-06-07 | American Hospital Supply Corporation | Method for treatment or prophylaxis of cardiac disorders |
US4346106A (en) * | 1981-05-14 | 1982-08-24 | E. R. Squibb & Sons, Inc. | Method for inhibiting onset of migraine headaches with nadolol compositions |
FI77669C (fi) * | 1983-04-13 | 1989-04-10 | Ciba Geigy Ag | 20-spiroxaner och analoger, som innehaoller en oeppen ring e, foerfarande foer deras framstaellning samt dessa innehaollande farmaceutiska preparat. |
US4752263A (en) * | 1984-06-29 | 1988-06-21 | Cuda International Corporation | Custom underwater diving system |
FR2634376B1 (fr) * | 1988-07-21 | 1992-04-17 | Farmalyoc | Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation |
US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
AU642066B2 (en) * | 1991-01-25 | 1993-10-07 | Nanosystems L.L.C. | X-ray contrast compositions useful in medical imaging |
US5123555A (en) * | 1991-05-01 | 1992-06-23 | Cap Snap Co. | Container cap having external bead |
US5190765A (en) * | 1991-06-27 | 1993-03-02 | Alza Corporation | Therapy delayed |
IT1252024B (it) * | 1991-11-29 | 1995-05-27 | Pirelli Transmissioni Ind Spa | Procedimento per la fabbricazione di cinghie dentate in materiale elastomerico,e cinghia dentata ottenuta mediante tale procedimento |
US5373004A (en) * | 1993-11-24 | 1994-12-13 | Wisconsin Alumni Research Foundation | 26,28-methylene-1α, 25-dihydroxyvitamin D2 compounds |
US5451652A (en) * | 1994-04-28 | 1995-09-19 | Arco Chemical Technology, L.P. | Polymers from propoxylated allyl alcohol |
US5747001A (en) * | 1995-02-24 | 1998-05-05 | Nanosystems, L.L.C. | Aerosols containing beclomethazone nanoparticle dispersions |
US5965034A (en) * | 1995-12-04 | 1999-10-12 | Mc Electronics Co., Ltd. | High frequency plasma process wherein the plasma is executed by an inductive structure in which the phase and anti-phase portion of the capacitive currents between the inductive structure and the plasma are balanced |
US6541479B1 (en) * | 1997-12-02 | 2003-04-01 | Massachusetts College Of Pharmacy | Calcium channel blockers |
US6047407A (en) * | 1997-12-29 | 2000-04-11 | Habel; Carolyn Louise | Hat with candles depicted thereon |
UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
US6429878B1 (en) * | 1999-12-28 | 2002-08-06 | Ge Medical Systems Global Technology Company, Llc | Display of text on medical images |
US6495235B2 (en) * | 2000-03-24 | 2002-12-17 | Matsushita Electric Industrial Co., Ltd. | Optical disk, substrate of the same, and mold for forming the substrate |
-
2001
- 2001-07-27 US US09/917,403 patent/US20020123485A1/en not_active Abandoned
- 2001-07-27 CA CA002415789A patent/CA2415789A1/en not_active Abandoned
- 2001-07-27 JP JP2002515312A patent/JP2004511435A/ja not_active Withdrawn
- 2001-07-27 AU AU2001279050A patent/AU2001279050B2/en not_active Ceased
- 2001-07-27 AU AU7905001A patent/AU7905001A/xx active Pending
- 2001-07-27 DE DE60120982T patent/DE60120982T2/de not_active Expired - Fee Related
- 2001-07-27 AT AT01957290T patent/ATE330633T1/de not_active IP Right Cessation
- 2001-07-27 EP EP01957290A patent/EP1303306B1/de not_active Expired - Lifetime
- 2001-07-27 PT PT01957290T patent/PT1303306E/pt unknown
- 2001-07-27 ES ES01957290T patent/ES2265437T3/es not_active Expired - Lifetime
- 2001-07-27 DK DK01957290T patent/DK1303306T3/da active
- 2001-07-27 US US10/343,166 patent/US20040235809A1/en not_active Abandoned
- 2001-07-27 WO PCT/US2001/023670 patent/WO2002009760A2/en active IP Right Grant
-
2005
- 2005-06-02 US US11/143,310 patent/US20050215537A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1303306A2 (de) | 2003-04-23 |
DK1303306T3 (da) | 2006-10-23 |
CA2415789A1 (en) | 2002-02-07 |
AU7905001A (en) | 2002-02-13 |
JP2004511435A (ja) | 2004-04-15 |
US20050215537A1 (en) | 2005-09-29 |
EP1303306B1 (de) | 2006-06-21 |
AU2001279050B2 (en) | 2006-10-19 |
ES2265437T3 (es) | 2007-02-16 |
US20020123485A1 (en) | 2002-09-05 |
DE60120982T2 (de) | 2007-02-08 |
PT1303306E (pt) | 2006-11-30 |
DE60120982D1 (de) | 2006-08-03 |
WO2002009760A3 (en) | 2003-01-23 |
WO2002009760A9 (en) | 2003-09-04 |
WO2002009760A2 (en) | 2002-02-07 |
US20040235809A1 (en) | 2004-11-25 |
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
Ref document number: 1303306 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |