DK0831911T3 - Kombinationsterapi til behandling af kongestivt hjertesvigt med spironolacton og angiotensin II-antagonist - Google Patents

Kombinationsterapi til behandling af kongestivt hjertesvigt med spironolacton og angiotensin II-antagonist

Info

Publication number
DK0831911T3
DK0831911T3 DK96919173T DK96919173T DK0831911T3 DK 0831911 T3 DK0831911 T3 DK 0831911T3 DK 96919173 T DK96919173 T DK 96919173T DK 96919173 T DK96919173 T DK 96919173T DK 0831911 T3 DK0831911 T3 DK 0831911T3
Authority
DK
Denmark
Prior art keywords
angiotensin
receptor antagonist
spironolactone
combination therapy
heart failure
Prior art date
Application number
DK96919173T
Other languages
English (en)
Inventor
Todd E Maclaughlan
Joseph R Schuh
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of DK0831911T3 publication Critical patent/DK0831911T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK96919173T 1995-06-07 1996-06-05 Kombinationsterapi til behandling af kongestivt hjertesvigt med spironolacton og angiotensin II-antagonist DK0831911T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48608995A 1995-06-07 1995-06-07
PCT/US1996/009342 WO1996040258A2 (en) 1995-06-07 1996-06-05 Spironolactone and angiotensin ii antagonist combination therapy for treatment of congestive heart failure

Publications (1)

Publication Number Publication Date
DK0831911T3 true DK0831911T3 (da) 2002-07-22

Family

ID=23930539

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96919173T DK0831911T3 (da) 1995-06-07 1996-06-05 Kombinationsterapi til behandling af kongestivt hjertesvigt med spironolacton og angiotensin II-antagonist

Country Status (16)

Country Link
US (1) US20040102423A1 (da)
EP (1) EP0831911B1 (da)
JP (1) JPH11509838A (da)
KR (1) KR19990022723A (da)
CN (1) CN1192696A (da)
AT (1) ATE216261T1 (da)
AU (1) AU6158096A (da)
BR (1) BR9608505A (da)
CA (1) CA2224222A1 (da)
CZ (1) CZ291268B6 (da)
DE (1) DE69620756T2 (da)
DK (1) DK0831911T3 (da)
ES (1) ES2175098T3 (da)
IL (1) IL122246A (da)
PT (1) PT831911E (da)
WO (1) WO1996040258A2 (da)

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CA2584342C (en) * 2004-10-20 2013-04-30 The Regents Of The University Of California Improved inhibitors for the soluble epoxide hydrolase
US9512125B2 (en) * 2004-11-19 2016-12-06 The Regents Of The University Of California Substituted pyrazolo[3.4-D] pyrimidines as anti-inflammatory agents
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US20110224223A1 (en) 2008-07-08 2011-09-15 The Regents Of The University Of California, A California Corporation MTOR Modulators and Uses Thereof
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US8476431B2 (en) * 2008-11-03 2013-07-02 Itellikine LLC Benzoxazole kinase inhibitors and methods of use
NZ594606A (en) 2009-01-30 2013-06-28 Takeda Pharmaceutical Fused ring compound and use thereof
JP5789252B2 (ja) 2009-05-07 2015-10-07 インテリカイン， エルエルシー 複素環式化合物およびその使用
US8980899B2 (en) 2009-10-16 2015-03-17 The Regents Of The University Of California Methods of inhibiting Ire1
ES2593256T3 (es) 2010-05-21 2016-12-07 Infinity Pharmaceuticals, Inc. Compuestos químicos, composiciones y métodos para las modulaciones de cinasas
EP2637669A4 (en) 2010-11-10 2014-04-02 Infinity Pharmaceuticals Inc Heterocyclic compounds and their use
ES2637113T3 (es) 2011-01-10 2017-10-10 Infinity Pharmaceuticals, Inc. Procedimientos para preparar isoquinolinonas y formas sólidas de isoquinolinonas
CN107899012A (zh) 2011-01-11 2018-04-13 戴麦里克斯生物科学有限公司 联合疗法
TWI592411B (zh) 2011-02-23 2017-07-21 英特爾立秦有限責任公司 激酶抑制劑之組合及其用途
CN102816126A (zh) * 2011-06-07 2012-12-12 中国药科大学 具有心血管活性的胺磺酰芳基取代的三氮唑类衍生物、其制备方法及用途
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TWI565709B (zh) 2011-07-19 2017-01-11 英菲尼提製藥股份有限公司 雜環化合物及其用途
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MX370814B (es) 2011-09-02 2020-01-08 Univ California Pirazolo[3,4-d]pirimidinas sustituidas y usos de las mismas.
US8940742B2 (en) 2012-04-10 2015-01-27 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
US8828998B2 (en) 2012-06-25 2014-09-09 Infinity Pharmaceuticals, Inc. Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
CN104995192A (zh) 2012-09-26 2015-10-21 加利福尼亚大学董事会 Ire1的调节
US9481667B2 (en) 2013-03-15 2016-11-01 Infinity Pharmaceuticals, Inc. Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
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ES2900806T3 (es) 2013-10-04 2022-03-18 Infinity Pharmaceuticals Inc Compuestos heterocíclicos y usos de los mismos
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US9708348B2 (en) 2014-10-03 2017-07-18 Infinity Pharmaceuticals, Inc. Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof
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Also Published As

Publication number Publication date
ES2175098T3 (es) 2002-11-16
CA2224222A1 (en) 1996-12-19
JPH11509838A (ja) 1999-08-31
US20040102423A1 (en) 2004-05-27
KR19990022723A (ko) 1999-03-25
EP0831911A2 (en) 1998-04-01
ATE216261T1 (de) 2002-05-15
IL122246A0 (en) 1998-04-05
DE69620756D1 (de) 2002-05-23
PT831911E (pt) 2002-09-30
EP0831911B1 (en) 2002-04-17
DE69620756T2 (de) 2002-11-14
WO1996040258A3 (en) 1997-01-23
CN1192696A (zh) 1998-09-09
BR9608505A (pt) 1999-07-06
CZ291268B6 (cs) 2003-01-15
AU6158096A (en) 1996-12-30
WO1996040258A2 (en) 1996-12-19
CZ384897A3 (cs) 1998-05-13
IL122246A (en) 2004-06-01

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