DD247452A5 - Verfahren zur herstellung von n-phenyl-4-phenyl-1-piperazin-carboxamidin und verwandten verbindungen - Google Patents

Verfahren zur herstellung von n-phenyl-4-phenyl-1-piperazin-carboxamidin und verwandten verbindungen Download PDF

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Publication number
DD247452A5
DD247452A5 DD86290764A DD29076486A DD247452A5 DD 247452 A5 DD247452 A5 DD 247452A5 DD 86290764 A DD86290764 A DD 86290764A DD 29076486 A DD29076486 A DD 29076486A DD 247452 A5 DD247452 A5 DD 247452A5
Authority
DD
German Democratic Republic
Prior art keywords
hydrogen
formula
alkyl
dichlorophenyl
item
Prior art date
Application number
DD86290764A
Other languages
German (de)
English (en)
Inventor
Jean-Claude Pascal
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by ������������@������@�K@�Kk�� filed Critical ������������@������@�K@�Kk��
Publication of DD247452A5 publication Critical patent/DD247452A5/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DD86290764A 1985-05-30 1986-05-30 Verfahren zur herstellung von n-phenyl-4-phenyl-1-piperazin-carboxamidin und verwandten verbindungen DD247452A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/739,393 US4713382A (en) 1985-05-30 1985-05-30 N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents

Publications (1)

Publication Number Publication Date
DD247452A5 true DD247452A5 (de) 1987-07-08

Family

ID=24972082

Family Applications (1)

Application Number Title Priority Date Filing Date
DD86290764A DD247452A5 (de) 1985-05-30 1986-05-30 Verfahren zur herstellung von n-phenyl-4-phenyl-1-piperazin-carboxamidin und verwandten verbindungen

Country Status (16)

Country Link
US (1) US4713382A (fr)
EP (1) EP0204265A1 (fr)
JP (1) JPS61280486A (fr)
KR (1) KR860008999A (fr)
CN (1) CN86103798A (fr)
AU (1) AU5805086A (fr)
DD (1) DD247452A5 (fr)
DK (1) DK253586A (fr)
ES (1) ES8708132A1 (fr)
FI (1) FI862279A (fr)
GR (1) GR861370B (fr)
HU (1) HU195201B (fr)
IL (1) IL78963A0 (fr)
NO (1) NO862138L (fr)
PT (1) PT82675B (fr)
ZA (1) ZA864023B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3040473B2 (ja) * 1991-08-14 2000-05-15 プロクター、エンド、ギャンブル、ファーマスーティカルズ、インコーポレーテッド 抗不整脈及び抗細動剤として有用な新規４−オキソ環式尿素類
AU2013292519B2 (en) * 2012-07-19 2017-12-07 Drexel University Sigma receptor ligands for modulating cellular protein homeostasis
US11117870B2 (en) 2017-11-01 2021-09-14 Drexel University Compounds, compositions, and methods for treating diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA574981A (fr) * 1959-04-28 H. Brown Edwin Dispositif etanche et coussinet a pression de fluide pour pompe centrifuge
GB948766A (en) * 1959-10-20 1964-02-05 May & Baker Ltd Trifluoromethylphenylpiperazine derivatives
US3655667A (en) * 1968-04-04 1972-04-11 Smith Kline French Lab 1-(2-benzoylcyclopropylmethyl)-4-phenylpiperazines
PH12016A (en) * 1972-09-22 1978-10-06 Rorer Inc William H Amidinoureas
US3793322A (en) * 1972-12-15 1974-02-19 Usv Pharma Corp 1,4-disubstituted piperazines
US3976643A (en) * 1973-07-13 1976-08-24 William H. Rorer, Inc. Guanidines
US3961056A (en) * 1974-02-11 1976-06-01 The Upjohn Company Substituted morpholine guanidines for the treatment of arrhythmic conditions
GB1514907A (en) * 1975-05-30 1978-06-21 Rorer Inc William H Process for the preparation of substituted phenylguanidines and substituted phenylguanidines when thus prepared
US4211867A (en) * 1976-03-19 1980-07-08 Mcneil Laboratories, Incorporated Nitrogen heterocyclic carboximidamide compounds
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process
EP0005385B1 (fr) * 1978-04-27 1982-09-01 LAROCHE NAVARRON S.A. Société dite: Dérivés de la pipérazine méthanimine, leur procédé de préparation et leurs applications en thérapeutique
CH643549A5 (de) * 1979-08-25 1984-06-15 Merz & Co N-(trimethoxybenzyl)-n'-phenylpiperazine.
US4374835A (en) * 1980-01-31 1983-02-22 Laroche-Navarron, S.A. Piperazine derivatives of theophylline

Also Published As

Publication number Publication date
AU5805086A (en) 1986-12-04
FI862279A (fi) 1986-12-01
HUT41016A (en) 1987-03-30
EP0204265A1 (fr) 1986-12-10
DK253586A (da) 1986-12-01
FI862279A0 (fi) 1986-05-29
CN86103798A (zh) 1987-06-10
ES555440A0 (es) 1987-10-16
US4713382A (en) 1987-12-15
GR861370B (en) 1986-09-17
ES8708132A1 (es) 1987-10-16
NO862138L (no) 1986-12-01
PT82675B (en) 1987-09-29
ZA864023B (en) 1988-01-27
DK253586D0 (da) 1986-05-29
JPS61280486A (ja) 1986-12-11
PT82675A (en) 1986-06-01
HU195201B (en) 1988-04-28
IL78963A0 (en) 1986-09-30
KR860008999A (ko) 1986-12-19

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