ZA864023B - N-phenyl-1-piperazine carboxamidines and related compounds as antiarrhythmic agents - Google Patents
N-phenyl-1-piperazine carboxamidines and related compounds as antiarrhythmic agentsInfo
- Publication number
- ZA864023B ZA864023B ZA864023A ZA864023A ZA864023B ZA 864023 B ZA864023 B ZA 864023B ZA 864023 A ZA864023 A ZA 864023A ZA 864023 A ZA864023 A ZA 864023A ZA 864023 B ZA864023 B ZA 864023B
- Authority
- ZA
- South Africa
- Prior art keywords
- carboxamidines
- piperazine
- phenyl
- related compounds
- antiarrhythmic agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/739,393 US4713382A (en) | 1985-05-30 | 1985-05-30 | N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA864023B true ZA864023B (en) | 1988-01-27 |
Family
ID=24972082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA864023A ZA864023B (en) | 1985-05-30 | 1986-05-29 | N-phenyl-1-piperazine carboxamidines and related compounds as antiarrhythmic agents |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4713382A (fr) |
| EP (1) | EP0204265A1 (fr) |
| JP (1) | JPS61280486A (fr) |
| KR (1) | KR860008999A (fr) |
| CN (1) | CN86103798A (fr) |
| AU (1) | AU5805086A (fr) |
| DD (1) | DD247452A5 (fr) |
| DK (1) | DK253586A (fr) |
| ES (1) | ES8708132A1 (fr) |
| FI (1) | FI862279A (fr) |
| GR (1) | GR861370B (fr) |
| HU (1) | HU195201B (fr) |
| IL (1) | IL78963A0 (fr) |
| NO (1) | NO862138L (fr) |
| PT (1) | PT82675B (fr) |
| ZA (1) | ZA864023B (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3040473B2 (ja) * | 1991-08-14 | 2000-05-15 | プロクター、エンド、ギャンブル、ファーマスーティカルズ、インコーポレーテッド | 抗不整脈及び抗細動剤として有用な新規４−オキソ環式尿素類 |
| AU2013292519B2 (en) * | 2012-07-19 | 2017-12-07 | Drexel University | Sigma receptor ligands for modulating cellular protein homeostasis |
| US11117870B2 (en) | 2017-11-01 | 2021-09-14 | Drexel University | Compounds, compositions, and methods for treating diseases |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA574981A (fr) * | 1959-04-28 | H. Brown Edwin | Dispositif etanche et coussinet a pression de fluide pour pompe centrifuge | |
| GB948766A (en) * | 1959-10-20 | 1964-02-05 | May & Baker Ltd | Trifluoromethylphenylpiperazine derivatives |
| US3655667A (en) * | 1968-04-04 | 1972-04-11 | Smith Kline French Lab | 1-(2-benzoylcyclopropylmethyl)-4-phenylpiperazines |
| PH12016A (en) * | 1972-09-22 | 1978-10-06 | Rorer Inc William H | Amidinoureas |
| US3793322A (en) * | 1972-12-15 | 1974-02-19 | Usv Pharma Corp | 1,4-disubstituted piperazines |
| US3976643A (en) * | 1973-07-13 | 1976-08-24 | William H. Rorer, Inc. | Guanidines |
| US3961056A (en) * | 1974-02-11 | 1976-06-01 | The Upjohn Company | Substituted morpholine guanidines for the treatment of arrhythmic conditions |
| GB1514907A (en) * | 1975-05-30 | 1978-06-21 | Rorer Inc William H | Process for the preparation of substituted phenylguanidines and substituted phenylguanidines when thus prepared |
| US4211867A (en) * | 1976-03-19 | 1980-07-08 | Mcneil Laboratories, Incorporated | Nitrogen heterocyclic carboximidamide compounds |
| US4138561A (en) * | 1977-09-30 | 1979-02-06 | Bristol-Myers Company | Cyanocarboxamidines and quinazoline process |
| EP0005385B1 (fr) * | 1978-04-27 | 1982-09-01 | LAROCHE NAVARRON S.A. Société dite: | Dérivés de la pipérazine méthanimine, leur procédé de préparation et leurs applications en thérapeutique |
| CH643549A5 (de) * | 1979-08-25 | 1984-06-15 | Merz & Co | N-(trimethoxybenzyl)-n'-phenylpiperazine. |
| US4374835A (en) * | 1980-01-31 | 1983-02-22 | Laroche-Navarron, S.A. | Piperazine derivatives of theophylline |
-
1985
- 1985-05-30 US US06/739,393 patent/US4713382A/en not_active Expired - Fee Related
-
1986
- 1986-05-28 GR GR861370A patent/GR861370B/el unknown
- 1986-05-28 PT PT82675A patent/PT82675B/pt unknown
- 1986-05-29 HU HU862258A patent/HU195201B/hu unknown
- 1986-05-29 FI FI862279A patent/FI862279A/fi not_active Application Discontinuation
- 1986-05-29 ES ES555440A patent/ES8708132A1/es not_active Expired
- 1986-05-29 KR KR1019860004227A patent/KR860008999A/ko not_active Application Discontinuation
- 1986-05-29 AU AU58050/86A patent/AU5805086A/en not_active Abandoned
- 1986-05-29 CN CN198686103798A patent/CN86103798A/zh active Pending
- 1986-05-29 EP EP86107310A patent/EP0204265A1/fr not_active Withdrawn
- 1986-05-29 ZA ZA864023A patent/ZA864023B/xx unknown
- 1986-05-29 NO NO862138A patent/NO862138L/no unknown
- 1986-05-29 DK DK253586A patent/DK253586A/da not_active Application Discontinuation
- 1986-05-29 JP JP61125592A patent/JPS61280486A/ja active Pending
- 1986-05-29 IL IL78963A patent/IL78963A0/xx unknown
- 1986-05-30 DD DD86290764A patent/DD247452A5/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU5805086A (en) | 1986-12-04 |
| FI862279A (fi) | 1986-12-01 |
| HUT41016A (en) | 1987-03-30 |
| EP0204265A1 (fr) | 1986-12-10 |
| DD247452A5 (de) | 1987-07-08 |
| DK253586A (da) | 1986-12-01 |
| FI862279A0 (fi) | 1986-05-29 |
| CN86103798A (zh) | 1987-06-10 |
| ES555440A0 (es) | 1987-10-16 |
| US4713382A (en) | 1987-12-15 |
| GR861370B (en) | 1986-09-17 |
| ES8708132A1 (es) | 1987-10-16 |
| NO862138L (no) | 1986-12-01 |
| PT82675B (en) | 1987-09-29 |
| DK253586D0 (da) | 1986-05-29 |
| JPS61280486A (ja) | 1986-12-11 |
| PT82675A (en) | 1986-06-01 |
| HU195201B (en) | 1988-04-28 |
| IL78963A0 (en) | 1986-09-30 |
| KR860008999A (ko) | 1986-12-19 |
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