DD216163A5 - Verfahren zur herstellung eines oral verabfolgbaren cefaclor-praeparates mit verzoegerter wirkstoffabgabe - Google Patents
Verfahren zur herstellung eines oral verabfolgbaren cefaclor-praeparates mit verzoegerter wirkstoffabgabe Download PDFInfo
- Publication number
- DD216163A5 DD216163A5 DD84264197A DD26419784A DD216163A5 DD 216163 A5 DD216163 A5 DD 216163A5 DD 84264197 A DD84264197 A DD 84264197A DD 26419784 A DD26419784 A DD 26419784A DD 216163 A5 DD216163 A5 DD 216163A5
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- DD
- German Democratic Republic
- Prior art keywords
- component
- granules
- ccl
- release
- preparation
- Prior art date
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- 238000000034 method Methods 0.000 title claims abstract description 46
- 229960005361 cefaclor Drugs 0.000 title claims abstract description 23
- 230000003111 delayed effect Effects 0.000 title claims abstract description 18
- 239000013543 active substance Substances 0.000 title description 6
- WKJGTOYAEQDNIA-IOOZKYRYSA-N (6r,7r)-7-[[(2r)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate Chemical compound O.C1([C@H](C(=O)N[C@@H]2C(N3C(=C(Cl)CS[C@@H]32)C(O)=O)=O)N)=CC=CC=C1 WKJGTOYAEQDNIA-IOOZKYRYSA-N 0.000 title 1
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- QYIYFLOTGYLRGG-GPCCPHFNSA-N cefaclor Chemical compound C1([C@H](C(=O)N[C@@H]2C(N3C(=C(Cl)CS[C@@H]32)C(O)=O)=O)N)=CC=CC=C1 QYIYFLOTGYLRGG-GPCCPHFNSA-N 0.000 claims abstract description 23
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58108289A JPS601128A (ja) | 1983-06-15 | 1983-06-15 | 作用持続型セフアクロル製剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DD216163A5 true DD216163A5 (de) | 1984-12-05 |
Family
ID=14480890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DD84264197A DD216163A5 (de) | 1983-06-15 | 1984-06-15 | Verfahren zur herstellung eines oral verabfolgbaren cefaclor-praeparates mit verzoegerter wirkstoffabgabe |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4713247A (cs) |
| EP (1) | EP0129382B1 (cs) |
| JP (1) | JPS601128A (cs) |
| KR (1) | KR910004573B1 (cs) |
| AT (1) | ATE56869T1 (cs) |
| AU (1) | AU568654B2 (cs) |
| BG (1) | BG60261B1 (cs) |
| CA (1) | CA1213218A (cs) |
| DD (1) | DD216163A5 (cs) |
| DE (1) | DE3483282D1 (cs) |
| DK (2) | DK291884A (cs) |
| ES (1) | ES8602407A1 (cs) |
| FI (1) | FI84556C (cs) |
| GB (1) | GB2141342B (cs) |
| GR (1) | GR81598B (cs) |
| HU (1) | HU193434B (cs) |
| IE (1) | IE58278B1 (cs) |
| IL (1) | IL72083A (cs) |
| NZ (1) | NZ208345A (cs) |
| PH (1) | PH19902A (cs) |
| PT (1) | PT78699B (cs) |
| RO (1) | RO88924A (cs) |
| ZA (1) | ZA844357B (cs) |
Families Citing this family (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5229132A (en) * | 1985-02-22 | 1993-07-20 | Grimberg Georges Serge | Non-absorbable gastrointestinal medicament provided for treating the two levels of the digestive tract at the same time |
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-
1983
- 1983-06-15 JP JP58108289A patent/JPS601128A/ja active Granted
-
1984
- 1984-05-30 US US06/615,242 patent/US4713247A/en not_active Expired - Lifetime
- 1984-05-31 NZ NZ208345A patent/NZ208345A/en unknown
- 1984-06-04 GR GR74913A patent/GR81598B/el unknown
- 1984-06-06 PT PT78699A patent/PT78699B/pt unknown
- 1984-06-08 AT AT84303908T patent/ATE56869T1/de not_active IP Right Cessation
- 1984-06-08 IE IE144484A patent/IE58278B1/en not_active IP Right Cessation
- 1984-06-08 DE DE8484303908T patent/DE3483282D1/de not_active Expired - Fee Related
- 1984-06-08 ZA ZA844357A patent/ZA844357B/xx unknown
- 1984-06-08 GB GB08414633A patent/GB2141342B/en not_active Expired
- 1984-06-08 EP EP84303908A patent/EP0129382B1/en not_active Expired - Lifetime
- 1984-06-11 PH PH30800A patent/PH19902A/en unknown
- 1984-06-13 RO RO84114861A patent/RO88924A/ro unknown
- 1984-06-13 BG BG065844A patent/BG60261B1/bg unknown
- 1984-06-13 FI FI842406A patent/FI84556C/fi not_active IP Right Cessation
- 1984-06-13 IL IL72083A patent/IL72083A/xx unknown
- 1984-06-14 HU HU842312A patent/HU193434B/hu not_active IP Right Cessation
- 1984-06-14 DK DK291884D patent/DK291884A/da unknown
- 1984-06-14 DK DK291884A patent/DK170922B1/da not_active IP Right Cessation
- 1984-06-15 CA CA000456659A patent/CA1213218A/en not_active Expired
- 1984-06-15 DD DD84264197A patent/DD216163A5/de unknown
- 1984-06-15 AU AU29418/84A patent/AU568654B2/en not_active Ceased
- 1984-06-15 KR KR1019840003359A patent/KR910004573B1/ko not_active Expired
- 1984-06-15 ES ES533901A patent/ES8602407A1/es not_active Expired
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| IF04 | In force in the year 2004 |
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