ATE56869T1 - Lang wirksame cefaclor-formulierung und deren herstellung. - Google Patents

Lang wirksame cefaclor-formulierung und deren herstellung.

Info

Publication number
ATE56869T1
ATE56869T1 AT84303908T AT84303908T ATE56869T1 AT E56869 T1 ATE56869 T1 AT E56869T1 AT 84303908 T AT84303908 T AT 84303908T AT 84303908 T AT84303908 T AT 84303908T AT E56869 T1 ATE56869 T1 AT E56869T1
Authority
AT
Austria
Prior art keywords
acting
long
cefaclor
manufacture
formulation
Prior art date
Application number
AT84303908T
Other languages
English (en)
Inventor
Teruo Sakamoto
Sadao Kawai
Kinzaburo Noda
Toyohiko Takeda
Hiroshi Kato
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE56869T1 publication Critical patent/ATE56869T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT84303908T 1983-06-15 1984-06-08 Lang wirksame cefaclor-formulierung und deren herstellung. ATE56869T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58108289A JPS601128A (ja) 1983-06-15 1983-06-15 作用持続型セフアクロル製剤
EP84303908A EP0129382B1 (de) 1983-06-15 1984-06-08 Lang wirksame Cefaclor-Formulierung und deren Herstellung

Publications (1)

Publication Number Publication Date
ATE56869T1 true ATE56869T1 (de) 1990-10-15

Family

ID=14480890

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84303908T ATE56869T1 (de) 1983-06-15 1984-06-08 Lang wirksame cefaclor-formulierung und deren herstellung.

Country Status (23)

Country Link
US (1) US4713247A (de)
EP (1) EP0129382B1 (de)
JP (1) JPS601128A (de)
KR (1) KR910004573B1 (de)
AT (1) ATE56869T1 (de)
AU (1) AU568654B2 (de)
BG (1) BG60261B2 (de)
CA (1) CA1213218A (de)
DD (1) DD216163A5 (de)
DE (1) DE3483282D1 (de)
DK (2) DK291884A (de)
ES (1) ES8602407A1 (de)
FI (1) FI84556C (de)
GB (1) GB2141342B (de)
GR (1) GR81598B (de)
HU (1) HU193434B (de)
IE (1) IE58278B1 (de)
IL (1) IL72083A (de)
NZ (1) NZ208345A (de)
PH (1) PH19902A (de)
PT (1) PT78699B (de)
RO (1) RO88924A (de)
ZA (1) ZA844357B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229132A (en) * 1985-02-22 1993-07-20 Grimberg Georges Serge Non-absorbable gastrointestinal medicament provided for treating the two levels of the digestive tract at the same time
JPS61210025A (ja) * 1985-03-14 1986-09-18 Teisan Seiyaku Kk 安定化された抗生物質複合顆粒製剤
AU591248B2 (en) * 1986-03-27 1989-11-30 Kinaform Technology, Inc. Sustained-release pharaceutical preparation
JPS62226926A (ja) * 1986-03-27 1987-10-05 Teisan Seiyaku Kk 持続性複合顆粒剤
JPH0714863B2 (ja) * 1986-06-02 1995-02-22 忠生 白石 時差溶解性の入浴剤
NZ223619A (en) * 1987-02-27 1990-10-26 Lilly Co Eli Sustained release tablet containing cefaclor, a hydrophilic polymer and an acrylic polymer
US4968508A (en) * 1987-02-27 1990-11-06 Eli Lilly And Company Sustained release matrix
BE1002079A4 (fr) * 1988-07-01 1990-06-19 S M B Lab Composition pharmaceutique d'erythromycine a liberation prolongee, sa preparation et son utilisation.
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5122384A (en) * 1989-05-05 1992-06-16 Kv Pharmaceutical Company Oral once-per-day organic nitrate formulation which does not induce tolerance
CA2085342A1 (en) * 1990-06-14 1991-12-15 Milton R. Kaplan Stable aqueous drug suspensions
GB9318641D0 (en) * 1993-09-08 1993-10-27 Edko Trading Representation Compositions
ES2079327B1 (es) * 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.
AU5107496A (en) * 1996-03-13 1997-10-01 Labtec Gesellschaft Fur Technologische Forschung Und Entwicklung Mbh Medicament preparation for angiotensin converting enzyme (ace)-inhibitors
US5948440A (en) * 1997-12-17 1999-09-07 Ranbaxy Laboratories Limited Modified release matrix formulation of cefaclor and cephalexin
ZA98728B (en) * 1998-01-29 1998-10-28 Ranbaxy Lab Ltd Modified release matrix formulations of cefactor and cephalexin
KR100296413B1 (ko) * 1998-04-01 2001-11-14 김선진 세파클러함유서방성정제
EP1191924A4 (de) * 1999-04-06 2005-02-09 Pharmaquest Ltd Pharmazeutische darreichungsform zur gepulsten verabreichung von (d-threo)-methylphenidat und einem weiteren zns stimulierenden stoff
US20030170181A1 (en) * 1999-04-06 2003-09-11 Midha Kamal K. Method for preventing abuse of methylphenidate
EP1180022A4 (de) * 1999-05-14 2004-01-07 Lilly Co Eli Prozess zur massenherstellung von pharmazeutischem material mit einheitlicher löslichkeit
US6596307B1 (en) 1999-06-15 2003-07-22 Eli Lilly And Company Process for preparing pharmaceutical bulk material having uniform dissolution
US7025989B2 (en) * 2000-02-24 2006-04-11 Advancis Pharmaceutical Corp. Multiple-delayed released antibiotic product, use and formulation thereof
US6991807B2 (en) * 2000-02-24 2006-01-31 Advancis Pharmaceutical, Corp. Antibiotic composition
CA2400818C (en) * 2000-02-24 2009-01-06 Advancis Pharmaceutical Corporation Antibiotic and antifungal compositions
WO2001062229A1 (en) * 2000-02-24 2001-08-30 Advanced Pharma, Inc. Therapeutic product, use and formulation thereof
CA2399856C (en) * 2000-02-24 2009-01-27 Edward M. Rudnic Antibiotic composition with inhibitor
WO2002056867A2 (en) * 2001-01-18 2002-07-25 Natco Pharma Limited Extended release pharmaceutical compositions containing beta-lactam antibiotics
CA2478121A1 (en) * 2002-03-07 2003-09-18 Advancis Pharmaceutical Corporation Antibiotic composition
WO2003094899A1 (es) * 2002-05-09 2003-11-20 Diffucap-Chemobras Química E Farmacéutica, Ltda. Nuevo procedimiento para la preparacion de composiciones de liberacion programada conteniendo (s) -1- [n-[1-(ethoxycarbonyl)-3-phenylpropyl]-l-alanyl]-l-proline, y al producto obtenido por dicho procedimiento
JP2006528185A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
JP2006528190A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
JP2006528189A (ja) * 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質産物、その使用法および製剤
CA2535398C (en) * 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
CA2535780A1 (en) * 2003-08-29 2005-03-17 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
JP2007513869A (ja) * 2003-09-15 2007-05-31 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US20060233878A1 (en) * 2003-09-30 2006-10-19 Lupin Limited Extended release formulation of beta-lactam antibiotics
AU2006235483B2 (en) * 2005-04-12 2010-11-25 Elan Pharma International Limited Controlled release compositions comprising a cephalosporin for the treatment of a bacterial infection
US20060287212A1 (en) * 2005-06-02 2006-12-21 Novozymes A/S Blends of inactive particles and active particles
CN101188997A (zh) 2005-06-02 2008-05-28 诺维信公司 非活性粒子和活性粒子的混合物
PT2391355T (pt) 2009-05-19 2017-02-21 Celgene Corp Formulações de 4-amino-2-(2,6-dioxopiperidin-3-il)isoindolino-1,3-diona
BR112014014805A2 (pt) * 2011-12-19 2017-06-13 Salix Pharmaceuticals Ltd processos para tratamento e prevenção de constipação induzida por opióide que utilizam composições orais de metilnaltrexona
CA2902911C (en) 2014-10-31 2017-06-27 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
CN104688701A (zh) * 2015-03-20 2015-06-10 江苏亚邦强生药业有限公司 一种头孢克洛片剂及其制备方法
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder
CN110408670A (zh) * 2019-08-19 2019-11-05 苏州盛达药业有限公司 一种酶催化合成头孢克洛的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2738303A (en) * 1952-07-18 1956-03-13 Smith Kline French Lab Sympathomimetic preparation
US3906086A (en) * 1971-07-19 1975-09-16 Richard G Powers Timed-release aspirin
JPS52139713A (en) * 1976-05-13 1977-11-21 Shionogi & Co Ltd Sustained release cefalexin preparations
US4250166A (en) * 1977-05-27 1981-02-10 Shionogi & Co., Ltd. Long acting preparation of cefalexin for effective treatments of bacterial infection sensitive to cefalexin
GR74995B (de) * 1980-08-27 1984-07-12 Ciba Geigy Ag
JPS5826816A (ja) * 1981-08-11 1983-02-17 Teisan Seiyaku Kk 球形顆粒からなる持続性複合顆粒剤

Also Published As

Publication number Publication date
EP0129382A3 (en) 1986-07-09
EP0129382A2 (de) 1984-12-27
BG60261B1 (bg) 1994-03-31
ZA844357B (en) 1985-06-26
BG60261B2 (en) 1994-03-31
DE3483282D1 (de) 1990-10-31
FI84556B (fi) 1991-09-13
IL72083A0 (en) 1984-10-31
FI842406A0 (fi) 1984-06-13
FI84556C (fi) 1991-12-27
DK291884A (da) 1984-12-16
KR850000242A (ko) 1985-02-26
FI842406A (fi) 1984-12-16
GR81598B (de) 1984-12-11
PT78699B (en) 1986-07-15
HU193434B (en) 1987-10-28
JPS601128A (ja) 1985-01-07
ES533901A0 (es) 1985-12-01
GB2141342A (en) 1984-12-19
AU568654B2 (en) 1988-01-07
JPS6232166B2 (de) 1987-07-13
IE841444L (en) 1984-12-15
KR910004573B1 (ko) 1991-07-06
DK291884D0 (da) 1984-06-14
DK170922B1 (da) 1996-03-18
CA1213218A (en) 1986-10-28
AU2941884A (en) 1984-12-20
IL72083A (en) 1987-10-30
PH19902A (en) 1986-08-13
ES8602407A1 (es) 1985-12-01
US4713247A (en) 1987-12-15
EP0129382B1 (de) 1990-09-26
RO88924A (ro) 1986-04-30
IE58278B1 (en) 1993-08-25
PT78699A (pt) 1985-01-01
GB8414633D0 (en) 1984-07-11
NZ208345A (en) 1986-12-05
HUT34692A (en) 1985-04-28
GB2141342B (en) 1986-11-12
DD216163A5 (de) 1984-12-05

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee