DD210453A5 - Verfahren zur herstellung von benzoxazin-2-onen - Google Patents

Verfahren zur herstellung von benzoxazin-2-onen Download PDF

Info

Publication number
DD210453A5
DD210453A5 DD83250508A DD25050883A DD210453A5 DD 210453 A5 DD210453 A5 DD 210453A5 DD 83250508 A DD83250508 A DD 83250508A DD 25050883 A DD25050883 A DD 25050883A DD 210453 A5 DD210453 A5 DD 210453A5
Authority
DD
German Democratic Republic
Prior art keywords
benzoxazin
butoxy
theory
group
yield
Prior art date
Application number
DD83250508A
Other languages
German (de)
English (en)
Inventor
Berthold Narr
Josef Nickl
Erich Mueller
Josef Roch
Walter Haarmann
Johannes Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DD210453A5 publication Critical patent/DD210453A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
DD83250508A 1982-05-06 1983-05-02 Verfahren zur herstellung von benzoxazin-2-onen DD210453A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823217012 DE3217012A1 (de) 1982-05-06 1982-05-06 Benzoxazin-2-one, deren herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
DD210453A5 true DD210453A5 (de) 1984-06-13

Family

ID=6162917

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83250508A DD210453A5 (de) 1982-05-06 1983-05-02 Verfahren zur herstellung von benzoxazin-2-onen

Country Status (25)

Country Link
US (1) US4518597A (da)
EP (1) EP0093922B1 (da)
JP (1) JPS58203979A (da)
KR (1) KR900006546B1 (da)
AT (1) ATE24501T1 (da)
AU (1) AU563453B2 (da)
CA (1) CA1204744A (da)
CS (1) CS236876B2 (da)
DD (1) DD210453A5 (da)
DE (2) DE3217012A1 (da)
DK (1) DK164860C (da)
ES (3) ES8402585A1 (da)
FI (1) FI79704C (da)
GB (1) GB2119382B (da)
GR (1) GR79255B (da)
HU (1) HU194842B (da)
IE (1) IE55481B1 (da)
IL (1) IL68573A (da)
NO (1) NO158738C (da)
NZ (1) NZ204143A (da)
PL (1) PL139119B1 (da)
PT (1) PT76627B (da)
SU (1) SU1138025A3 (da)
YU (1) YU42854B (da)
ZA (1) ZA833190B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3439281A1 (de) * 1984-10-26 1986-04-30 Bayer Ag, 5090 Leverkusen Chromogene 4,4-diaryl-2-oxo-benzo-3,1-oxazine, ihre herstellung und verwendung
US5663169A (en) * 1992-08-07 1997-09-02 Merck & Co., Inc. Benzoxazinones as inhibitors of HIV reverse transcriptase
IL106507A (en) * 1992-08-07 1997-11-20 Merck & Co Inc Pharmaceutical compositions containing benzoxazinones and some novel compounds of this type
US5874430A (en) * 1996-10-02 1999-02-23 Dupont Pharmaceuticals Company 4,4-disubstitued-1,4-dihydro-2H-3,1-benzoxazin-2-ones useful as HIV reverse transcriptase inhibitors and intermediates and processes for making the same
US5965729A (en) 1997-02-05 1999-10-12 Merck & Co., Inc. Process for the crystallization of a reverse transcriptase inhibitor using an anti-solvent
US6509334B1 (en) * 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
UA73119C2 (en) * 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
CA2712367C (en) * 2008-01-17 2016-01-19 Bayer Schering Pharma Aktiengesellschaft Sulphoximine-substituted quinazoline derivatives as immunomodulators, their preparation and use as medicaments
WO2015120059A1 (en) * 2014-02-04 2015-08-13 Yates Charles Ryan Inhibitors of paxillin function and related compositions and methods

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3526621A (en) * 1966-08-03 1970-09-01 Farmaceutical Italia Soc Substituted 3,1-benzoxazin-2-one
US3542774A (en) * 1968-07-05 1970-11-24 Warner Lambert Pharmaceutical 3,4-dihydrobenzoxazinones
CH624395A5 (da) * 1976-01-08 1981-07-31 Ciba Geigy Ag
SU843739A3 (ru) * 1978-02-17 1981-06-30 Карл Томэ Гмбх (Фирма) Способ получени карбостириловыхили ОКСиНдОлОВыХ пРОизВОдНыХ
US4442111A (en) * 1981-07-25 1984-04-10 Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung Antithrombotic sulfimino and sulfoximino indolinones-2

Also Published As

Publication number Publication date
IE831032L (en) 1983-11-06
GB8312344D0 (en) 1983-06-08
GB2119382A (en) 1983-11-16
HU194842B (en) 1988-03-28
IE55481B1 (en) 1990-09-26
PL139119B1 (en) 1986-12-31
JPS58203979A (ja) 1983-11-28
ES526724A0 (es) 1984-07-01
FI831412A0 (fi) 1983-04-26
ES522104A0 (es) 1984-02-01
NO158738C (no) 1988-11-16
US4518597A (en) 1985-05-21
PT76627B (de) 1986-02-26
IL68573A0 (en) 1983-09-30
DK195583A (da) 1983-11-07
ES8402585A1 (es) 1984-02-01
AU1426583A (en) 1983-11-10
SU1138025A3 (ru) 1985-01-30
FI79704B (fi) 1989-10-31
GB2119382B (en) 1985-09-18
AU563453B2 (en) 1987-07-09
EP0093922A3 (en) 1984-01-25
EP0093922B1 (de) 1986-12-30
IL68573A (en) 1986-10-31
NO158738B (no) 1988-07-18
DK195583D0 (da) 1983-05-03
DE3217012A1 (de) 1983-11-10
ATE24501T1 (de) 1987-01-15
DK164860B (da) 1992-08-31
NO831599L (no) 1983-11-07
NZ204143A (en) 1986-02-21
ES8406453A1 (es) 1984-07-01
ZA833190B (en) 1985-01-30
YU42854B (en) 1988-12-31
PT76627A (de) 1983-06-01
KR840004736A (ko) 1984-10-24
DE3368621D1 (en) 1987-02-05
YU95783A (en) 1985-10-31
PL241806A1 (en) 1984-08-13
GR79255B (da) 1984-10-22
EP0093922A2 (de) 1983-11-16
CS236876B2 (en) 1985-05-15
FI79704C (fi) 1990-02-12
ES8406454A1 (es) 1984-07-01
DK164860C (da) 1993-01-11
ES526723A0 (es) 1984-07-01
FI831412L (fi) 1983-11-07
KR900006546B1 (ko) 1990-09-13
CA1204744A (en) 1986-05-20

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Legal Events

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ENJ Ceased due to non-payment of renewal fee