DK195583A - Fremgangsmaade til fremstilling af benzoxazin-2-oner - Google Patents
Fremgangsmaade til fremstilling af benzoxazin-2-oner Download PDFInfo
- Publication number
- DK195583A DK195583A DK195583A DK195583A DK195583A DK 195583 A DK195583 A DK 195583A DK 195583 A DK195583 A DK 195583A DK 195583 A DK195583 A DK 195583A DK 195583 A DK195583 A DK 195583A
- Authority
- DK
- Denmark
- Prior art keywords
- group
- hydrogen
- benzoxazin
- oner
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
Description
R4 er hydrogen eller akyl, R5 er hydrogen eller halogen, nitro eller alkyl, og *6 er hydrogen eller halogen eller alkyl fremstilles ved en række fremgangsmåder, der er kendte til fremstilling af analoge forbindelser.
Forbindelserne har værdifulde farmakologiske egenskaber især antithrombotiske virkninger.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19823217012 DE3217012A1 (de) | 1982-05-06 | 1982-05-06 | Benzoxazin-2-one, deren herstellung und diese verbindungen enthaltende arzneimittel |
DE3217012 | 1982-05-06 |
Publications (4)
Publication Number | Publication Date |
---|---|
DK195583D0 DK195583D0 (da) | 1983-05-03 |
DK195583A true DK195583A (da) | 1983-11-07 |
DK164860B DK164860B (da) | 1992-08-31 |
DK164860C DK164860C (da) | 1993-01-11 |
Family
ID=6162917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK195583A DK164860C (da) | 1982-05-06 | 1983-05-03 | Analogifremgangsmaade til fremstilling af benzoxazin-2-oner |
Country Status (25)
Country | Link |
---|---|
US (1) | US4518597A (da) |
EP (1) | EP0093922B1 (da) |
JP (1) | JPS58203979A (da) |
KR (1) | KR900006546B1 (da) |
AT (1) | ATE24501T1 (da) |
AU (1) | AU563453B2 (da) |
CA (1) | CA1204744A (da) |
CS (1) | CS236876B2 (da) |
DD (1) | DD210453A5 (da) |
DE (2) | DE3217012A1 (da) |
DK (1) | DK164860C (da) |
ES (3) | ES8402585A1 (da) |
FI (1) | FI79704C (da) |
GB (1) | GB2119382B (da) |
GR (1) | GR79255B (da) |
HU (1) | HU194842B (da) |
IE (1) | IE55481B1 (da) |
IL (1) | IL68573A (da) |
NO (1) | NO158738C (da) |
NZ (1) | NZ204143A (da) |
PL (1) | PL139119B1 (da) |
PT (1) | PT76627B (da) |
SU (1) | SU1138025A3 (da) |
YU (1) | YU42854B (da) |
ZA (1) | ZA833190B (da) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3439281A1 (de) * | 1984-10-26 | 1986-04-30 | Bayer Ag, 5090 Leverkusen | Chromogene 4,4-diaryl-2-oxo-benzo-3,1-oxazine, ihre herstellung und verwendung |
US5665720A (en) * | 1992-08-07 | 1997-09-09 | Merck & Co., Inc. | Benzoxazinones as inhibitors of HIV reverse transcriptase |
IL106507A (en) * | 1992-08-07 | 1997-11-20 | Merck & Co Inc | Pharmaceutical compositions containing benzoxazinones and some novel compounds of this type |
US5874430A (en) * | 1996-10-02 | 1999-02-23 | Dupont Pharmaceuticals Company | 4,4-disubstitued-1,4-dihydro-2H-3,1-benzoxazin-2-ones useful as HIV reverse transcriptase inhibitors and intermediates and processes for making the same |
US5965729A (en) | 1997-02-05 | 1999-10-12 | Merck & Co., Inc. | Process for the crystallization of a reverse transcriptase inhibitor using an anti-solvent |
US6509334B1 (en) | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
UA73119C2 (en) * | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
EP2247579B1 (en) * | 2008-01-17 | 2012-04-18 | Bayer Pharma Aktiengesellschaft | Sulphoximine-substituted quinazoline derivatives as immunomodulators, their preparation and use as medicaments |
US9834525B2 (en) | 2014-02-04 | 2017-12-05 | University Of Tennessee Research Foundation | Inhibitors of paxillin function and related compositions and methods |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3526621A (en) * | 1966-08-03 | 1970-09-01 | Farmaceutical Italia Soc | Substituted 3,1-benzoxazin-2-one |
US3542774A (en) * | 1968-07-05 | 1970-11-24 | Warner Lambert Pharmaceutical | 3,4-dihydrobenzoxazinones |
CH624395A5 (da) * | 1976-01-08 | 1981-07-31 | Ciba Geigy Ag | |
SU843739A3 (ru) * | 1978-02-17 | 1981-06-30 | Карл Томэ Гмбх (Фирма) | Способ получени карбостириловыхили ОКСиНдОлОВыХ пРОизВОдНыХ |
US4442111A (en) * | 1981-07-25 | 1984-04-10 | Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung | Antithrombotic sulfimino and sulfoximino indolinones-2 |
-
1982
- 1982-05-06 DE DE19823217012 patent/DE3217012A1/de not_active Withdrawn
-
1983
- 1983-04-22 DE DE8383103980T patent/DE3368621D1/de not_active Expired
- 1983-04-22 AT AT83103980T patent/ATE24501T1/de not_active IP Right Cessation
- 1983-04-22 EP EP83103980A patent/EP0093922B1/de not_active Expired
- 1983-04-26 FI FI831412A patent/FI79704C/fi not_active IP Right Cessation
- 1983-04-26 SU SU833583668A patent/SU1138025A3/ru active
- 1983-04-27 YU YU957/83A patent/YU42854B/xx unknown
- 1983-05-02 DD DD83250508A patent/DD210453A5/de not_active IP Right Cessation
- 1983-05-02 PT PT76627A patent/PT76627B/pt unknown
- 1983-05-03 DK DK195583A patent/DK164860C/da not_active IP Right Cessation
- 1983-05-04 CS CS833145A patent/CS236876B2/cs unknown
- 1983-05-04 KR KR1019830001917A patent/KR900006546B1/ko not_active IP Right Cessation
- 1983-05-04 HU HU831540A patent/HU194842B/hu not_active IP Right Cessation
- 1983-05-04 IL IL68573A patent/IL68573A/xx unknown
- 1983-05-04 GR GR71308A patent/GR79255B/el unknown
- 1983-05-05 GB GB08312344A patent/GB2119382B/en not_active Expired
- 1983-05-05 NZ NZ204143A patent/NZ204143A/en unknown
- 1983-05-05 ZA ZA833190A patent/ZA833190B/xx unknown
- 1983-05-05 NO NO831599A patent/NO158738C/no unknown
- 1983-05-05 IE IE1032/83A patent/IE55481B1/en not_active IP Right Cessation
- 1983-05-05 ES ES522104A patent/ES8402585A1/es not_active Expired
- 1983-05-05 PL PL1983241806A patent/PL139119B1/pl unknown
- 1983-05-05 CA CA000427530A patent/CA1204744A/en not_active Expired
- 1983-05-05 AU AU14265/83A patent/AU563453B2/en not_active Ceased
- 1983-05-06 JP JP58079222A patent/JPS58203979A/ja active Pending
- 1983-10-25 ES ES526723A patent/ES526723A0/es active Granted
- 1983-10-25 ES ES526724A patent/ES8406454A1/es not_active Expired
-
1984
- 1984-06-06 US US06/617,797 patent/US4518597A/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |