DD210279A5 - Verfahren zur herstellung von cephalosporinverbindungen - Google Patents

Verfahren zur herstellung von cephalosporinverbindungen Download PDF

Info

Publication number
DD210279A5
DD210279A5 DD83249303A DD24930383A DD210279A5 DD 210279 A5 DD210279 A5 DD 210279A5 DD 83249303 A DD83249303 A DD 83249303A DD 24930383 A DD24930383 A DD 24930383A DD 210279 A5 DD210279 A5 DD 210279A5
Authority
DD
German Democratic Republic
Prior art keywords
methyl
cephem
carboxylate
ethyl
compounds
Prior art date
Application number
DD83249303A
Other languages
German (de)
English (en)
Inventor
Hajime Kamachi
Jun Okumura
Takayuki Naito
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DD210279A5 publication Critical patent/DD210279A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DD83249303A 1982-03-29 1983-03-29 Verfahren zur herstellung von cephalosporinverbindungen DD210279A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/363,313 US4457929A (en) 1982-03-29 1982-03-29 3-Quaternary ammonium methyl)-substituted cephalosporin derivatives

Publications (1)

Publication Number Publication Date
DD210279A5 true DD210279A5 (de) 1984-06-06

Family

ID=23429716

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83249303A DD210279A5 (de) 1982-03-29 1983-03-29 Verfahren zur herstellung von cephalosporinverbindungen

Country Status (33)

Country Link
US (1) US4457929A (fr)
JP (1) JPS58198490A (fr)
KR (1) KR900005047B1 (fr)
AT (1) AT383129B (fr)
AU (1) AU564971B2 (fr)
BE (1) BE896292A (fr)
CA (1) CA1213883A (fr)
CH (1) CH655118A5 (fr)
CS (1) CS264257B2 (fr)
DD (1) DD210279A5 (fr)
DE (1) DE3311300A1 (fr)
DK (1) DK161024C (fr)
EG (1) EG16029A (fr)
ES (2) ES8600312A1 (fr)
FI (1) FI74974C (fr)
FR (1) FR2523973B1 (fr)
GB (1) GB2117770B (fr)
GR (1) GR77907B (fr)
HU (1) HU189676B (fr)
IE (1) IE54791B1 (fr)
IL (1) IL68244A0 (fr)
IT (1) IT1164634B (fr)
LU (1) LU84717A1 (fr)
MY (1) MY8700944A (fr)
NL (1) NL8301053A (fr)
NZ (1) NZ203360A (fr)
OA (1) OA07354A (fr)
PH (1) PH18959A (fr)
PT (1) PT76460B (fr)
SE (1) SE453092B (fr)
SU (3) SU1205772A3 (fr)
YU (1) YU43654B (fr)
ZA (1) ZA832156B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963542A (en) * 1976-09-08 1990-10-16 Takeda Chemical Industries, Ltd. Cephalosporin derivatives
US6331308B1 (en) 1981-10-26 2001-12-18 Battelle Memorial Institute Method and apparatus for providing long term protection from intrusion by insects and other cold blooded animals
US6060076A (en) * 1981-10-26 2000-05-09 Battelle Memorial Institute Method and apparatus for providing long term protection from intrusion by insects and other cold blooded animals
US6099850A (en) * 1981-10-26 2000-08-08 Battelle Memorial Institute Termite and boring insect barrier for the protection of wooden structures
US5925368A (en) * 1981-10-26 1999-07-20 Battelle Memorial Institute Protection of wooden objects in direct contact with soil from pest invasion
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
DE3409431A1 (de) * 1983-10-08 1985-04-18 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
GB8424692D0 (en) * 1984-10-01 1984-11-07 Glaxo Group Ltd Chemical compounds
EP0182210B1 (fr) * 1984-11-12 1991-02-27 Banyu Pharmaceutical Co., Ltd. Dérivés de céphalosporine
US4868173A (en) * 1984-11-20 1989-09-19 Ici Pharma Cephalosporin derivatives
US4883868A (en) * 1984-12-27 1989-11-28 Banyu Pharmaceutical Co., Ltd. 7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives
JPH068300B2 (ja) * 1985-08-02 1994-02-02 萬有製薬株式会社 新規セフアロスポリン誘導体
IE862850L (en) * 1985-11-21 1987-05-21 Inst Animal Health Ltd Intermediates for the preparation of beta-lactam antibiotics
US4814328A (en) * 1986-03-19 1989-03-21 Banyu Pharmaceutical Co., Ltd. Cephalosporin derivatives, and antibacterial agents
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
US5244890A (en) * 1988-06-06 1993-09-14 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US6852328B1 (en) 1989-09-01 2005-02-08 Battelle Memorial Institute K1-53 Method and device for protection of wooden objects proximate soil from pest invasion
US6319511B1 (en) 1989-09-01 2001-11-20 Battelle Memorial Institute Termite and boring insect barrier for the protection of wooden structures
US6572872B2 (en) 1989-09-01 2003-06-03 Battelle Memorial Institute Method and apparatus for providing long term protection from intrusion by insects and other cold blooded animals
GB9107973D0 (en) * 1991-04-15 1991-05-29 Fujisawa Pharmaceutical Co New cephem compounds and process for preparation thereof
US5985304A (en) 1998-02-25 1999-11-16 Battelle Memorial Institute Barrier preventing wood pest access to wooden structures
KR100380323B1 (ko) * 2000-01-26 2003-04-16 한국과학기술연구원 Ｎ-메틸-ｎ-(3-메틸-1,3-티아졸리움-2-일)아미노기를함유한 신규한 세팔로스포린 화합물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DE2760484C2 (fr) * 1976-04-14 1992-12-03 Takeda Chemical Industries, Ltd., Osaka, Jp
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
JPS5559196A (en) * 1978-10-27 1980-05-02 Glaxo Group Ltd Cephalosporin compound
CA1131618A (fr) * 1978-10-27 1982-09-14 Cynthia H. O'callaghan Composes de cephalosporine
GR78245B (fr) * 1980-09-12 1984-09-26 Ciba Geigy Ag

Also Published As

Publication number Publication date
KR900005047B1 (ko) 1990-07-18
GB2117770A (en) 1983-10-19
HU189676B (en) 1986-07-28
FI74974B (fi) 1987-12-31
YU71683A (en) 1986-02-28
SU1373325A3 (ru) 1988-02-07
DK95383A (da) 1983-09-30
CH655118A5 (de) 1986-03-27
ATA110983A (de) 1986-10-15
DE3311300C2 (fr) 1991-05-16
LU84717A1 (fr) 1983-12-05
MY8700944A (en) 1987-12-31
SE453092B (sv) 1988-01-11
PT76460B (en) 1986-03-11
SU1205772A3 (ru) 1986-01-15
SE8301726L (sv) 1983-11-25
SU1313351A3 (ru) 1987-05-23
KR840004119A (ko) 1984-10-06
PH18959A (en) 1985-11-26
IE830687L (en) 1983-09-29
IL68244A0 (en) 1983-06-15
EG16029A (en) 1987-03-30
AU564971B2 (en) 1987-09-03
ZA832156B (en) 1984-08-29
ES520983A0 (es) 1985-10-01
IE54791B1 (en) 1990-02-14
ES527661A0 (es) 1985-04-16
AU1186483A (en) 1983-10-06
JPS58198490A (ja) 1983-11-18
GR77907B (fr) 1984-09-25
FI831013A0 (fi) 1983-03-24
BE896292A (fr) 1983-09-28
GB2117770B (en) 1985-10-09
CS264257B2 (en) 1989-06-13
NZ203360A (en) 1985-08-16
CA1213883A (fr) 1986-11-12
GB8308519D0 (en) 1983-05-05
YU43654B (en) 1989-10-31
DK95383D0 (da) 1983-02-25
CS219083A2 (en) 1988-09-16
NL8301053A (nl) 1983-10-17
ES8504205A1 (es) 1985-04-16
SE8301726D0 (sv) 1983-03-28
DE3311300A1 (de) 1983-09-29
IT8348006A0 (it) 1983-03-28
FI74974C (fi) 1988-04-11
FI831013L (fi) 1983-09-30
FR2523973B1 (fr) 1986-09-12
OA07354A (fr) 1984-08-31
DK161024B (da) 1991-05-21
DK161024C (da) 1991-10-28
FR2523973A1 (fr) 1983-09-30
AT383129B (de) 1987-05-25
US4457929A (en) 1984-07-03
IT1164634B (it) 1987-04-15
ES8600312A1 (es) 1985-10-01
PT76460A (en) 1983-04-01

Similar Documents

Publication Publication Date Title
DD210279A5 (de) Verfahren zur herstellung von cephalosporinverbindungen
DE2727753C2 (fr)
EP0088320B1 (fr) Dérivés de céphalosporine et procédé pour leur préparation
CH646178A5 (de) Cephalosporinantibiotika.
DE2439880C3 (de) (6R, 7R)-3-Carbamoyloxymethyl-7- [2-(fur-2-yl)-2methoxyiminoacetamido] -ceph-S-em^carbonsäure und Verfahren zur ihrer Herstellung
AT369749B (de) Verfahren zur herstellung von neuen cephalosporinantibiotika
EP0137441A2 (fr) Dérivés de céphalosporine et procédé pour leur préparation
EP0137440A2 (fr) Dérivés de céphalosporine et procédé pour leur préparation
DE3307550C2 (fr)
CH647784A5 (de) Cephalosporinantibiotika.
DE2943427A1 (de) Cephalosporinverbindungen
CH649557A5 (de) Cephalosporinantibiotika.
CH651574A5 (de) Cephalosporinantibiotika, ihre herstellung und pharmazeutische zubereitungen.
EP0035161B1 (fr) Céphalosporines, procédé pour leur préparation et compositions pharmaceutiques les contenant
AT391319B (de) Verfahren zur herstellung von neuen cephalosporinverbindungen
DE2943437A1 (de) Cephalosporinverbindungen
CH627758A5 (en) Process for the preparation of the syn isomer or a mixture of the syn isomer and anti isomer of 7beta-acylamidoceph-3-em-4-carboxylic acids with the antibiotic activity
DE3901405A1 (de) Cephalosporinderivate und verfahren zu ihrer herstellung
CH634326A5 (de) 2-hydroxyiminoacetamido-cephemcarbonsaeuren und ihre herstellung.
DE3323462A1 (de) Cephalosporin-antibiotika
DE2818025A1 (de) Verfahren zur herstellung von cephemverbindungen
AT384613B (de) Verfahren zur herstellung von neuen cephalosporinderivaten
AT375663B (de) Verfahren zur herstellung von neuen cephalosporinantibiotika
DE2236422C2 (de) Cephalosporinverbindungen und Verfahren zu deren Herstellung
EP0049814B1 (fr) Dérivés de céphalosporine, leur préparation et compositions pharmaceutiques les contenant

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee