DD209457A5 - Verfahren zur herstellung von 4-piperazinyl-4-phenyl-chinazolin-derivaten - Google Patents

Verfahren zur herstellung von 4-piperazinyl-4-phenyl-chinazolin-derivaten Download PDF

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Publication number
DD209457A5
DD209457A5 DD83247791A DD24779183A DD209457A5 DD 209457 A5 DD209457 A5 DD 209457A5 DD 83247791 A DD83247791 A DD 83247791A DD 24779183 A DD24779183 A DD 24779183A DD 209457 A5 DD209457 A5 DD 209457A5
Authority
DD
German Democratic Republic
Prior art keywords
phenyl
formula
derivatives
halogen
piperazinyl
Prior art date
Application number
DD83247791A
Other languages
German (de)
English (en)
Inventor
Kathleen Biziere
Andre Hallot
Jean-Paul Kan
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DD209457A5 publication Critical patent/DD209457A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DD83247791A 1982-02-08 1983-02-08 Verfahren zur herstellung von 4-piperazinyl-4-phenyl-chinazolin-derivaten DD209457A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8201988A FR2521144A1 (fr) 1982-02-08 1982-02-08 Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant

Publications (1)

Publication Number Publication Date
DD209457A5 true DD209457A5 (de) 1984-05-09

Family

ID=9270762

Family Applications (1)

Application Number Title Priority Date Filing Date
DD83247791A DD209457A5 (de) 1982-02-08 1983-02-08 Verfahren zur herstellung von 4-piperazinyl-4-phenyl-chinazolin-derivaten

Country Status (30)

Country Link
US (1) US4540696A (xx)
EP (1) EP0087337B1 (xx)
JP (1) JPS58146573A (xx)
KR (1) KR900003301B1 (xx)
AT (1) ATE19244T1 (xx)
AU (1) AU554802B2 (xx)
CA (1) CA1249274A (xx)
CS (1) CS228944B2 (xx)
DD (1) DD209457A5 (xx)
DE (1) DE3362999D1 (xx)
DK (1) DK154972C (xx)
EG (1) EG15649A (xx)
ES (1) ES8401060A1 (xx)
FI (1) FI73983C (xx)
FR (1) FR2521144A1 (xx)
GR (1) GR76744B (xx)
HU (1) HU190710B (xx)
IE (1) IE54427B1 (xx)
IL (1) IL67746A (xx)
MA (1) MA19696A1 (xx)
NO (1) NO159171C (xx)
NZ (1) NZ203209A (xx)
OA (1) OA07320A (xx)
PH (1) PH18862A (xx)
PL (1) PL138118B1 (xx)
PT (1) PT76146A (xx)
SG (1) SG2089G (xx)
SU (1) SU1287750A3 (xx)
YU (1) YU30183A (xx)
ZA (1) ZA83541B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521144A1 (fr) * 1982-02-08 1983-08-12 Sanofi Sa Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant
JPS60146891A (ja) * 1984-01-05 1985-08-02 Mitsubishi Chem Ind Ltd 〔２，３−ｄ〕チエノピリミジン誘導体およびその塩
JPS6165873A (ja) * 1984-09-07 1986-04-04 Mitsui Petrochem Ind Ltd ２−ピペラジノピリミジン誘導体
EP1618094B1 (en) * 2003-04-30 2007-09-05 The Institutes for Pharmaceutical Discovery, LLC Substituted heteroaryls as inhibitors of protein tyrosine phosphatases
MXPA06005019A (es) * 2003-11-03 2006-07-06 Warner Lambert Co Nuevos inhibidores de la recaptacion de norpinefrina para el tratamiento de transtornos del sistema nervioso central.
AU2004289303A1 (en) * 2003-11-10 2005-05-26 Synta Pharmaceuticals, Corp. Fused heterocyclic compounds
JP4796622B2 (ja) * 2005-04-11 2011-10-19 エフ．ホフマン−ラ ロシュ アーゲー （３，４−ジヒドロ−キナゾリン−２−イル）−インダン−１−イル−アミン

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3305553A (en) * 1965-10-18 1967-02-21 Parke Davis & Co 2-aminoquinazoline derivatives
US3509141A (en) * 1966-09-15 1970-04-28 Ciba Geigy Corp 2-amino-quinazolines
US3646028A (en) * 1966-09-15 1972-02-29 Ciba Geigy Corp Certain 2-amino-4-phenyl-3 4-dihydroquinazolines
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3635979A (en) * 1969-09-29 1972-01-18 Pfizer Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
JPS5692875A (en) * 1979-12-27 1981-07-27 Dainippon Pharmaceut Co Ltd 2-aminoquinazoline derivative
JPS56118421A (en) * 1980-02-25 1981-09-17 Nitto Electric Ind Co Ltd Heat-shrinkable polyimide film and production thereof
FR2514765A1 (fr) * 1981-10-21 1983-04-22 Sanofi Sa Nouveaux derives de la phenyl-4 quinazoline actifs sur le systeme nerveux central
FR2521144A1 (fr) * 1982-02-08 1983-08-12 Sanofi Sa Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant

Also Published As

Publication number Publication date
FI73983C (fi) 1987-12-10
AU1117683A (en) 1983-08-18
MA19696A1 (fr) 1983-10-01
OA07320A (fr) 1984-08-31
FI830338L (fi) 1983-08-09
NO159171C (no) 1988-12-07
KR900003301B1 (ko) 1990-05-14
SG2089G (en) 1989-06-02
PL138118B1 (en) 1986-08-30
DK154972C (da) 1989-06-12
IE54427B1 (en) 1989-10-11
NO830398L (no) 1983-08-09
IL67746A0 (en) 1983-05-15
AU554802B2 (en) 1986-09-04
CS228944B2 (en) 1984-05-14
IL67746A (en) 1986-08-31
ES519598A0 (es) 1983-11-16
CA1249274A (en) 1989-01-24
SU1287750A3 (ru) 1987-01-30
NO159171B (no) 1988-08-29
DK50383A (da) 1983-08-09
PH18862A (en) 1985-10-21
NZ203209A (en) 1985-07-12
DE3362999D1 (en) 1986-05-22
EP0087337A1 (fr) 1983-08-31
KR840003627A (ko) 1984-09-15
YU30183A (en) 1985-10-31
HU190710B (en) 1986-10-28
US4540696A (en) 1985-09-10
EP0087337B1 (fr) 1986-04-16
EG15649A (en) 1986-09-30
ES8401060A1 (es) 1983-11-16
FI73983B (fi) 1987-08-31
JPS58146573A (ja) 1983-09-01
FI830338A0 (fi) 1983-02-01
PL240469A1 (en) 1983-11-21
ATE19244T1 (de) 1986-05-15
PT76146A (fr) 1983-02-01
FR2521144B1 (xx) 1984-11-09
FR2521144A1 (fr) 1983-08-12
ZA83541B (en) 1983-10-26
IE830111L (en) 1983-08-08
GR76744B (xx) 1984-08-30
DK154972B (da) 1989-01-16
DK50383D0 (da) 1983-02-07

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ENJ Ceased due to non-payment of renewal fee