ATE19244T1 - 2-piperazinyl-4-phenyl-quinazolin-derivate mit antidepressiven eigenschaften, verfahren zu deren herstellung und diese enthaltende arzneimitteln. - Google Patents

2-piperazinyl-4-phenyl-quinazolin-derivate mit antidepressiven eigenschaften, verfahren zu deren herstellung und diese enthaltende arzneimitteln.

Info

Publication number
ATE19244T1
ATE19244T1 AT83400232T AT83400232T ATE19244T1 AT E19244 T1 ATE19244 T1 AT E19244T1 AT 83400232 T AT83400232 T AT 83400232T AT 83400232 T AT83400232 T AT 83400232T AT E19244 T1 ATE19244 T1 AT E19244T1
Authority
AT
Austria
Prior art keywords
piperazinyl
phenyl
preparation
quinazoline derivatives
medications containing
Prior art date
Application number
AT83400232T
Other languages
English (en)
Inventor
Kathleen Biziere
Andre Hallot
Jean-Paul Kan
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of ATE19244T1 publication Critical patent/ATE19244T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT83400232T 1982-02-08 1983-02-04 2-piperazinyl-4-phenyl-quinazolin-derivate mit antidepressiven eigenschaften, verfahren zu deren herstellung und diese enthaltende arzneimitteln. ATE19244T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8201988A FR2521144A1 (fr) 1982-02-08 1982-02-08 Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant
EP83400232A EP0087337B1 (de) 1982-02-08 1983-02-04 2-Piperazinyl-4-phenyl-quinazolin-Derivate mit antidepressiven Eigenschaften, Verfahren zu deren Herstellung und diese enthaltende Arzneimitteln

Publications (1)

Publication Number Publication Date
ATE19244T1 true ATE19244T1 (de) 1986-05-15

Family

ID=9270762

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83400232T ATE19244T1 (de) 1982-02-08 1983-02-04 2-piperazinyl-4-phenyl-quinazolin-derivate mit antidepressiven eigenschaften, verfahren zu deren herstellung und diese enthaltende arzneimitteln.

Country Status (30)

Country Link
US (1) US4540696A (de)
EP (1) EP0087337B1 (de)
JP (1) JPS58146573A (de)
KR (1) KR900003301B1 (de)
AT (1) ATE19244T1 (de)
AU (1) AU554802B2 (de)
CA (1) CA1249274A (de)
CS (1) CS228944B2 (de)
DD (1) DD209457A5 (de)
DE (1) DE3362999D1 (de)
DK (1) DK154972C (de)
EG (1) EG15649A (de)
ES (1) ES8401060A1 (de)
FI (1) FI73983C (de)
FR (1) FR2521144A1 (de)
GR (1) GR76744B (de)
HU (1) HU190710B (de)
IE (1) IE54427B1 (de)
IL (1) IL67746A (de)
MA (1) MA19696A1 (de)
NO (1) NO159171C (de)
NZ (1) NZ203209A (de)
OA (1) OA07320A (de)
PH (1) PH18862A (de)
PL (1) PL138118B1 (de)
PT (1) PT76146A (de)
SG (1) SG2089G (de)
SU (1) SU1287750A3 (de)
YU (1) YU30183A (de)
ZA (1) ZA83541B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521144A1 (fr) * 1982-02-08 1983-08-12 Sanofi Sa Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant
JPS60146891A (ja) * 1984-01-05 1985-08-02 Mitsubishi Chem Ind Ltd 〔２，３−ｄ〕チエノピリミジン誘導体およびその塩
JPS6165873A (ja) * 1984-09-07 1986-04-04 Mitsui Petrochem Ind Ltd ２−ピペラジノピリミジン誘導体
AU2004236239A1 (en) * 2003-04-30 2004-11-18 The Institutes For Pharmaceutical Discovery, Llc Substituted heteroaryls as inhibitors of protein tyrosine phosphatases
WO2005042501A1 (en) * 2003-11-03 2005-05-12 Warner-Lambert Company Llc Novel norepinephrine reuptake inhibitors for the treatment of central nervous system disorders
EP1687002A4 (de) * 2003-11-10 2008-07-23 Synta Pharmaceuticals Corp Kondensierte heterozyklische verbindungen
AU2006233867A1 (en) * 2005-04-11 2006-10-19 F. Hoffmann-La Roche Ag (3,4-dihydro-quinazolin-2-yl)-indan-1-yl-amines

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3305553A (en) * 1965-10-18 1967-02-21 Parke Davis & Co 2-aminoquinazoline derivatives
US3646028A (en) * 1966-09-15 1972-02-29 Ciba Geigy Corp Certain 2-amino-4-phenyl-3 4-dihydroquinazolines
US3509141A (en) * 1966-09-15 1970-04-28 Ciba Geigy Corp 2-amino-quinazolines
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3635979A (en) * 1969-09-29 1972-01-18 Pfizer Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
JPS5692875A (en) * 1979-12-27 1981-07-27 Dainippon Pharmaceut Co Ltd 2-aminoquinazoline derivative
JPS56118421A (en) * 1980-02-25 1981-09-17 Nitto Electric Ind Co Ltd Heat-shrinkable polyimide film and production thereof
FR2514765A1 (fr) * 1981-10-21 1983-04-22 Sanofi Sa Nouveaux derives de la phenyl-4 quinazoline actifs sur le systeme nerveux central
FR2521144A1 (fr) * 1982-02-08 1983-08-12 Sanofi Sa Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant

Also Published As

Publication number Publication date
PL138118B1 (en) 1986-08-30
ES519598A0 (es) 1983-11-16
CS228944B2 (en) 1984-05-14
FR2521144A1 (fr) 1983-08-12
IL67746A (en) 1986-08-31
DD209457A5 (de) 1984-05-09
AU1117683A (en) 1983-08-18
DE3362999D1 (en) 1986-05-22
IL67746A0 (en) 1983-05-15
YU30183A (en) 1985-10-31
NO159171C (no) 1988-12-07
IE830111L (en) 1983-08-08
IE54427B1 (en) 1989-10-11
PH18862A (en) 1985-10-21
SU1287750A3 (ru) 1987-01-30
ES8401060A1 (es) 1983-11-16
FI73983B (fi) 1987-08-31
EP0087337A1 (de) 1983-08-31
EP0087337B1 (de) 1986-04-16
AU554802B2 (en) 1986-09-04
DK154972B (da) 1989-01-16
EG15649A (en) 1986-09-30
DK154972C (da) 1989-06-12
FI830338A0 (fi) 1983-02-01
PL240469A1 (en) 1983-11-21
US4540696A (en) 1985-09-10
NO159171B (no) 1988-08-29
KR900003301B1 (ko) 1990-05-14
FR2521144B1 (de) 1984-11-09
ZA83541B (en) 1983-10-26
NZ203209A (en) 1985-07-12
FI73983C (fi) 1987-12-10
NO830398L (no) 1983-08-09
CA1249274A (en) 1989-01-24
SG2089G (en) 1989-06-02
PT76146A (fr) 1983-02-01
HU190710B (en) 1986-10-28
DK50383D0 (da) 1983-02-07
MA19696A1 (fr) 1983-10-01
OA07320A (fr) 1984-08-31
JPS58146573A (ja) 1983-09-01
GR76744B (de) 1984-08-30
KR840003627A (ko) 1984-09-15
FI830338L (fi) 1983-08-09
DK50383A (da) 1983-08-09

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee