ATE8618T1 - Derivate von biphenyl-alkyl-carboxylaten, deren herstellungsverfahren und deren verwendung als arzneimittel. - Google Patents

Derivate von biphenyl-alkyl-carboxylaten, deren herstellungsverfahren und deren verwendung als arzneimittel.

Info

Publication number
ATE8618T1
ATE8618T1 AT82401870T AT82401870T ATE8618T1 AT E8618 T1 ATE8618 T1 AT E8618T1 AT 82401870 T AT82401870 T AT 82401870T AT 82401870 T AT82401870 T AT 82401870T AT E8618 T1 ATE8618 T1 AT E8618T1
Authority
AT
Austria
Prior art keywords
derivatives
manufacture
processes
alkyl carboxylates
medicinal products
Prior art date
Application number
AT82401870T
Other languages
English (en)
Inventor
Henri Cousse
Gilbert Mouzin
Jean-Pierre Tarayre
Jean-Pierre Rieu
Original Assignee
Pierre Fabre S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre S.A. filed Critical Pierre Fabre S.A.
Application granted granted Critical
Publication of ATE8618T1 publication Critical patent/ATE8618T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT82401870T 1981-10-14 1982-10-12 Derivate von biphenyl-alkyl-carboxylaten, deren herstellungsverfahren und deren verwendung als arzneimittel. ATE8618T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8119316A FR2514355A1 (fr) 1981-10-14 1981-10-14 Derives de biphenyl alcoyl carboxylates, leur procede de preparation et leur utilisation comme medicaments
EP82401870A EP0077720B1 (de) 1981-10-14 1982-10-12 Derivate von Biphenyl-Alkyl-Carboxylaten, deren Herstellungsverfahren und deren Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ATE8618T1 true ATE8618T1 (de) 1984-08-15

Family

ID=9263029

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82401870T ATE8618T1 (de) 1981-10-14 1982-10-12 Derivate von biphenyl-alkyl-carboxylaten, deren herstellungsverfahren und deren verwendung als arzneimittel.

Country Status (6)

Country Link
US (1) US4510142A (de)
EP (1) EP0077720B1 (de)
JP (1) JPS5877849A (de)
AT (1) ATE8618T1 (de)
DE (1) DE3260465D1 (de)
FR (1) FR2514355A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1201127A (en) * 1982-09-10 1986-02-25 Katsuhiro Uchida Biphenylylpropionic acid derivative, process for preparing the same and pharmaceutical composition containing the same
IT1212840B (it) * 1983-11-28 1989-11-30 Zambeletti Spa L Derivati di acidi bifenililalcanoici, loro preparazione e composizioni farmaceutiche che licontengono.
JPH0764834B2 (ja) * 1985-11-29 1995-07-12 サントリー株式会社 プロリルエンドペプチダーゼ阻害活性を有する新規ピロリジンアミド誘導体およびその製法並びに用途
DK406686D0 (da) * 1986-08-26 1986-08-26 Hans Bundgaard Carboxylsyrederivater
JPS6425782A (en) * 1987-03-27 1989-01-27 Yoshitomi Pharmaceutical Benzopyranopyridineacetic acid ester compound
US4916209A (en) * 1987-12-23 1990-04-10 Pfizer Inc. Bioabsorbable polydepsipeptide, preparation and use thereof
DE60234453D1 (de) * 2001-07-02 2009-12-31 High Point Pharmaceuticals Llc Substituierte piperazin- und diazepanderivate zur verwendung als histamin h3 rezeptormodulatoren
US6900233B2 (en) * 2002-02-28 2005-05-31 Aventis Pharma Deutschland Gmbh Substituted 3-phenyl-5-alkoxy-3H-(1,3,4)-oxadiazol-2-ones, pharmaceutical composition and method for treating obesity thereof
AU2015209759B2 (en) * 2014-01-23 2018-11-29 Sixera Pharma Ab New kallikrein 7 inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1091403A (en) * 1964-01-24 1967-11-15 Boots Pure Drug Co Ltd Therapeutically active phenylalkane derivatives
FR6978M (de) * 1967-12-13 1969-05-27
IT1044222B (it) * 1972-05-23 1980-03-20 Zambeletti Spa L Bifenilil alcanoilaminopiridine ad attivita anti infiammatoria di lunga durata
CS185694B2 (en) * 1974-07-17 1978-10-31 Ishihara Sangyo Kaisha Herbicidal agent
DK149748C (da) * 1978-08-25 1987-04-06 Daiichi Seiyaku Co Analogifremgangsmaade til fremstilling af n-phenethylacetamidforbindelser
ATE1855T1 (de) * 1978-09-08 1982-12-15 Imperial Chemical Industries Plc Antiarthritische hydroxyessigsaeurederivate, pharmazeutische zusammensetzungen daraus und verfahren zu ihrer herstellung.
US4390715A (en) * 1980-07-18 1983-06-28 Commonwealth Scientific And Industrial Research Organization Pentafluorobenzyl esters

Also Published As

Publication number Publication date
DE3260465D1 (en) 1984-08-30
EP0077720B1 (de) 1984-07-25
FR2514355B1 (de) 1984-01-13
EP0077720A1 (de) 1983-04-27
JPS5877849A (ja) 1983-05-11
US4510142A (en) 1985-04-09
FR2514355A1 (fr) 1983-04-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee