ATE17483T1 - Loesliche, n2-substituierte derivate von 2,4diamino-5-benzyl-pyrimidinen, verfahren zu deren herstellung und diese enthaltende arzneimittel. - Google Patents

Loesliche, n2-substituierte derivate von 2,4diamino-5-benzyl-pyrimidinen, verfahren zu deren herstellung und diese enthaltende arzneimittel.

Info

Publication number
ATE17483T1
ATE17483T1 AT82400495T AT82400495T ATE17483T1 AT E17483 T1 ATE17483 T1 AT E17483T1 AT 82400495 T AT82400495 T AT 82400495T AT 82400495 T AT82400495 T AT 82400495T AT E17483 T1 ATE17483 T1 AT E17483T1
Authority
AT
Austria
Prior art keywords
substituted derivatives
soluble
pyrimidines
benzyl
4diamino
Prior art date
Application number
AT82400495T
Other languages
English (en)
Inventor
Claude Laruelle
Marcel Lepant
Original Assignee
Panmedica Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panmedica Sa filed Critical Panmedica Sa
Application granted granted Critical
Publication of ATE17483T1 publication Critical patent/ATE17483T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT82400495T 1981-03-20 1982-03-18 Loesliche, n2-substituierte derivate von 2,4diamino-5-benzyl-pyrimidinen, verfahren zu deren herstellung und diese enthaltende arzneimittel. ATE17483T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8105592A FR2502152A1 (fr) 1981-03-20 1981-03-20 Nouveaux derives solubles n2 substitues de la diamino-2,4-benzyl-5-pyrimidines, leur procede de preparation et medicaments les contenant
EP82400495A EP0061397B1 (de) 1981-03-20 1982-03-18 Lösliche, N2-substituierte Derivate von 2,4-Diamino-5-benzyl-pyrimidinen, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ATE17483T1 true ATE17483T1 (de) 1986-02-15

Family

ID=9256463

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82400495T ATE17483T1 (de) 1981-03-20 1982-03-18 Loesliche, n2-substituierte derivate von 2,4diamino-5-benzyl-pyrimidinen, verfahren zu deren herstellung und diese enthaltende arzneimittel.

Country Status (13)

Country Link
US (1) US4415574A (de)
EP (1) EP0061397B1 (de)
JP (1) JPS57169472A (de)
AT (1) ATE17483T1 (de)
AU (1) AU555274B2 (de)
CA (1) CA1180015A (de)
DE (2) DE3268481D1 (de)
ES (1) ES8302669A1 (de)
FR (1) FR2502152A1 (de)
GR (1) GR75938B (de)
MA (1) MA19413A1 (de)
OA (1) OA07044A (de)
ZA (1) ZA821785B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5707996A (en) * 1995-11-06 1998-01-13 Macleod Pharmaceuticals, Inc. Pharmaceutical solution and methods for preparation thereof
CA2463989C (en) * 2001-10-17 2012-01-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pyrimidine derivatives, pharmaceutical compositions containing these compounds, the use thereof and process for the preparation thereof
EP1725540B1 (de) * 2004-03-05 2012-09-12 F.Hoffmann-La Roche Ag Diaminopyrimidine als p2x3- und p2x2/3-antagonisten
CA2620129C (en) * 2005-09-01 2014-12-23 F. Hoffmann-La Roche Ag Diaminopyrimidines as p2x3 and p2x2/3 modulators
ES2601178T3 (es) * 2005-09-01 2017-02-14 F. Hoffmann-La Roche Ag Diaminopirimidinas como moduladores de P2X3 y P3X2/3
CN101296907B (zh) * 2005-09-01 2013-03-27 弗·哈夫曼-拉罗切有限公司 作为p2x3和p2x2/3调节剂的二氨基嘧啶类
JP6788524B2 (ja) * 2017-02-28 2020-11-25 ダイコク電機株式会社 遊技用装置及び遊技場システム

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1407971A (en) * 1971-04-16 1975-10-01 Wellcome Found 2,4-diamino -4-3,4,5-triethoxybenzyl pyrimidine and methods of preparation therefor
FR2358148A1 (fr) * 1976-07-12 1978-02-10 Dick Pr Derives de 2,4-diaminopyrimidines et leur mise en solution en association avec des sulfamides
FR2397407A2 (fr) * 1977-07-11 1979-02-09 Dick Pierre Derives de 2,4-diamino pyrimidines et leur mise en solution en association avec des sulfamides

Also Published As

Publication number Publication date
OA07044A (fr) 1983-12-31
ZA821785B (en) 1983-02-23
GR75938B (de) 1984-08-02
AU8172882A (en) 1982-09-23
ES510618A0 (es) 1983-02-01
DE3268481D1 (en) 1986-02-27
ES8302669A1 (es) 1983-02-01
CA1180015A (en) 1984-12-27
JPH0340026B2 (de) 1991-06-17
JPS57169472A (en) 1982-10-19
DE61397T1 (de) 1983-10-13
AU555274B2 (en) 1986-09-18
MA19413A1 (fr) 1982-10-01
FR2502152B1 (de) 1984-01-20
EP0061397B1 (de) 1986-01-15
FR2502152A1 (fr) 1982-09-24
EP0061397A1 (de) 1982-09-29
US4415574A (en) 1983-11-15

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