ATE48835T1 - Chinolylglycinamidderivate, verfahren zu ihrer herstellung und therapeutische verwendung als psychotrope. - Google Patents

Chinolylglycinamidderivate, verfahren zu ihrer herstellung und therapeutische verwendung als psychotrope.

Info

Publication number
ATE48835T1
ATE48835T1 AT86400973T AT86400973T ATE48835T1 AT E48835 T1 ATE48835 T1 AT E48835T1 AT 86400973 T AT86400973 T AT 86400973T AT 86400973 T AT86400973 T AT 86400973T AT E48835 T1 ATE48835 T1 AT E48835T1
Authority
AT
Austria
Prior art keywords
quinolylglycinamide
derivatives
psychotrops
production
therapeutic use
Prior art date
Application number
AT86400973T
Other languages
English (en)
Inventor
Jean-Claude Vernieres
Etienne Mendes
Peter Keane
Jacques Simiand
Michel Morre
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of ATE48835T1 publication Critical patent/ATE48835T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT86400973T 1985-05-06 1986-05-06 Chinolylglycinamidderivate, verfahren zu ihrer herstellung und therapeutische verwendung als psychotrope. ATE48835T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8507247A FR2581382B1 (fr) 1985-05-06 1985-05-06 Derives n-(quinolyl) glycinamides, leur procede de preparation et leur application therapeutique en tant que psychotropes
EP86400973A EP0205362B1 (de) 1985-05-06 1986-05-06 Chinolylglycinamidderivate, Verfahren zu ihrer Herstellung und therapeutische Verwendung als Psychotrope

Publications (1)

Publication Number Publication Date
ATE48835T1 true ATE48835T1 (de) 1990-01-15

Family

ID=9319228

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86400973T ATE48835T1 (de) 1985-05-06 1986-05-06 Chinolylglycinamidderivate, verfahren zu ihrer herstellung und therapeutische verwendung als psychotrope.

Country Status (16)

Country Link
US (1) US4788188A (de)
EP (1) EP0205362B1 (de)
JP (1) JPH0739395B2 (de)
KR (1) KR860008982A (de)
AT (1) ATE48835T1 (de)
AU (1) AU582235B2 (de)
CA (1) CA1263957A (de)
DE (1) DE3667660D1 (de)
DK (1) DK204686A (de)
ES (1) ES8800161A1 (de)
FR (1) FR2581382B1 (de)
GR (1) GR861169B (de)
IL (1) IL78691A (de)
NZ (1) NZ216048A (de)
PT (1) PT82512B (de)
ZA (1) ZA863382B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8610980D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Heterocyclic fused tricyclic compounds
FR2632861B1 (fr) * 1988-06-15 1990-11-09 Sanofi Sa Derives d'amino-4 carboxy-3 quinoleines et naphtyridines, leur procede de preparation et leur application comme medicaments
DK273689A (da) * 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
FR2632305B1 (fr) * 1988-06-06 1992-05-15 Sanofi Sa Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique
FR2632639B1 (fr) * 1988-06-09 1990-10-05 Sanofi Sa Derives d'amino-4 carboxy-3 naphtyridines, leur preparation et compositions pharmaceutiques qui les contiennent
US5493027A (en) * 1993-01-22 1996-02-20 Board Of Regents, The University Of Texas System Anticonvulsive agents and uses thereof
US5783700A (en) * 1997-07-03 1998-07-21 Nichols; Alfred C. Quinolic acid derivatives
DE19960924C2 (de) * 1999-12-17 2002-08-01 Therapeutics Gmbh G.O.T. Amphiphile Polyamine, deren Anwendungen
EP1554572B1 (de) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2456911A (en) * 1945-05-04 1948-12-21 Wyeth Corp Disubstituted acetamidyl derivatives of amino quinolines
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
GB1177548A (en) * 1967-11-28 1970-01-14 Ici Ltd Phenoxy-and Anilino-Alkanoic Acid Amides
FR8491M (de) * 1968-12-31 1973-07-27
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds

Also Published As

Publication number Publication date
PT82512B (pt) 1988-03-03
IL78691A0 (en) 1986-08-31
JPS6226271A (ja) 1987-02-04
DK204686D0 (da) 1986-05-02
EP0205362A1 (de) 1986-12-17
FR2581382B1 (fr) 1987-06-26
AU5714286A (en) 1987-11-12
DK204686A (da) 1986-11-07
ES8800161A1 (es) 1987-11-16
AU582235B2 (en) 1989-03-16
NZ216048A (en) 1988-09-29
CA1263957A (fr) 1989-12-19
IL78691A (en) 1989-09-28
GR861169B (en) 1986-09-01
ES554305A0 (es) 1987-11-16
KR860008982A (ko) 1986-12-19
PT82512A (fr) 1986-06-01
DE3667660D1 (de) 1990-01-25
FR2581382A1 (fr) 1986-11-07
JPH0739395B2 (ja) 1995-05-01
EP0205362B1 (de) 1989-12-20
US4788188A (en) 1988-11-29
ZA863382B (en) 1987-01-28

Similar Documents

Publication Publication Date Title
ATE151764T1 (de) Neue benzopyran-derivate, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltenden zubereitungen
CS231885A3 (en) Process for preparing imidazole derivatives
ATE48835T1 (de) Chinolylglycinamidderivate, verfahren zu ihrer herstellung und therapeutische verwendung als psychotrope.
DE3581566D1 (de) Oxindol-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte.
ATE46164T1 (de) 1,4:3,6-dianhydro-hexit-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
AU541976B2 (en) Isoquinoline derivatives
ATE38988T1 (de) Imidazolylphenyl-tetrahydropyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
ATE30719T1 (de) Imino-2-pyrrolidine, verfahren zu ihrer herstellung und ihre therapeutische verwendung.
ATE9330T1 (de) Phenethanolamin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ATE61573T1 (de) Neue kristalline salze von aryloxypropanolaminen, verfahren zu ihrer herstellung und ihre verwendung.
ATE2794T1 (de) 1-n-alkylsisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
YU6087A (en) Process for obtaining 2-benzimidazole-ilalkylthiosulphinyl or sulphonyl derivatives
ATE12643T1 (de) 2-0- und 5-0-substituierte 1.4;3.6-dianhydrohexit-mononitrate, verfahren zu ihrer herstellung und pharmazeutische zubereitung.
PT82175A (de) Neue 3-pyridylmethylnaphthylderivate verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
ATE12390T1 (de) Basisch substituierte anthranilsaeuren, verfahren zu ihrer herstellung und ihre verwendung.
ATE7298T1 (de) Basisch substituierte 5-phenyltetrazole, verfahren zu ihrer herstellung und ihre verwendung als heilmittel.
ATE33837T1 (de) Azolylmethylcycloacetale, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ES517874A0 (es) Procedimiento de preparacion de derivados de diaza-3,7a-cicloherta-(j,k)-fluorenos.
DE3469527D1 (en) Nortropine derivative, process for its preparation and its use
ATE25517T1 (de) Delta-1-pyrrolin-thiolactimaether und verfahren zu ihrer herstellung.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee