FR2632305B1 - Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique - Google Patents

Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique

Info

Publication number
FR2632305B1
FR2632305B1 FR8807498A FR8807498A FR2632305B1 FR 2632305 B1 FR2632305 B1 FR 2632305B1 FR 8807498 A FR8807498 A FR 8807498A FR 8807498 A FR8807498 A FR 8807498A FR 2632305 B1 FR2632305 B1 FR 2632305B1
Authority
FR
France
Prior art keywords
naphtyridines
quinoleins
aroyl
therapeutics
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8807498A
Other languages
English (en)
Other versions
FR2632305A1 (fr
Inventor
Etienne Mendes
Jean-Claude Vernieres
Peter Eugene Keane
Andre Bachy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi SA filed Critical Sanofi SA
Priority to FR8807498A priority Critical patent/FR2632305B1/fr
Priority to DK273689A priority patent/DK273689A/da
Priority to PT90748A priority patent/PT90748B/pt
Priority to ES89401548T priority patent/ES2063153T3/es
Priority to CA000601729A priority patent/CA1337073C/fr
Priority to KR1019890007791A priority patent/KR910000731A/ko
Priority to AT89401548T priority patent/ATE104282T1/de
Priority to EP89401548A priority patent/EP0346208B1/fr
Priority to ZA894250A priority patent/ZA894250B/xx
Priority to JP1143956A priority patent/JP2766672B2/ja
Priority to DE68914515T priority patent/DE68914515T2/de
Priority to NZ229413A priority patent/NZ229413A/en
Priority to AU36035/89A priority patent/AU624825B2/en
Priority to US07/362,105 priority patent/US5026711A/en
Priority to IE179789A priority patent/IE63429B1/en
Publication of FR2632305A1 publication Critical patent/FR2632305A1/fr
Application granted granted Critical
Publication of FR2632305B1 publication Critical patent/FR2632305B1/fr
Priority to LV960245A priority patent/LV5799B4/xx
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C07D215/60—N-oxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8807498A 1988-06-06 1988-06-06 Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique Expired - Fee Related FR2632305B1 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR8807498A FR2632305B1 (fr) 1988-06-06 1988-06-06 Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique
DK273689A DK273689A (da) 1988-06-06 1989-06-02 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
JP1143956A JP2766672B2 (ja) 1988-06-06 1989-06-05 ４―アミノ―３―カルボキシキノリン類およびナフチリジン類、製法および医薬用途
CA000601729A CA1337073C (fr) 1988-06-06 1989-06-05 4-amino quinoleines et naphtyridines; methode de preparation et utilisation comme agents therapeutiques
KR1019890007791A KR910000731A (ko) 1988-06-06 1989-06-05 4-아미노 3-카르복시 퀴놀린 및 나프티리딘, 그 제조방법 및 그의 의약품으로서 용도
AT89401548T ATE104282T1 (de) 1988-06-06 1989-06-05 4-amino-chinoline und naphthyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
EP89401548A EP0346208B1 (fr) 1988-06-06 1989-06-05 Amino-4 quinoléines et naphtyridines, leur procédé de préparation et leur application comme médicaments
ZA894250A ZA894250B (en) 1988-06-06 1989-06-05 4-amino quinolines and naphthyridines,process for their preparation and their use as medicines
PT90748A PT90748B (pt) 1988-06-06 1989-06-05 Processo par a preparacao de 4-amino-3-carboxi-quinoleinas e - naftiridinas
DE68914515T DE68914515T2 (de) 1988-06-06 1989-06-05 4-Amino-chinoline und Naphthyridine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
ES89401548T ES2063153T3 (es) 1988-06-06 1989-06-05 Amino-4 quinoleinas y naftiridinas, su procedimiento de preparacion y su aplicacion como medicamentos.
NZ229413A NZ229413A (en) 1988-06-06 1989-06-06 Quinoline and naphthyridine derivatives and pharmaceutical compositions
AU36035/89A AU624825B2 (en) 1988-06-06 1989-06-06 4-amino quinolines and naphthyridines, process for their preparation and their use as medicines
US07/362,105 US5026711A (en) 1988-06-06 1989-06-06 4-amino quinolines and naphthyridines and their use as medicines
IE179789A IE63429B1 (en) 1988-06-06 1989-06-12 4-amino quinolines and naphthyridines process for their preparation and their use as medicines
LV960245A LV5799B4 (lv) 1988-06-06 1996-07-16 4-Aminohinolini un naftiridini to iegusanas panemiens un to izmantosana par medikamentiem

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8807498A FR2632305B1 (fr) 1988-06-06 1988-06-06 Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
FR2632305A1 FR2632305A1 (fr) 1989-12-08
FR2632305B1 true FR2632305B1 (fr) 1992-05-15

Family

ID=9366972

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8807498A Expired - Fee Related FR2632305B1 (fr) 1988-06-06 1988-06-06 Amino-4 aroyl-3 quinoleines et naphtyridines, leur procede de preparation et leur application en therapeutique

Country Status (2)

Country Link
FR (1) FR2632305B1 (fr)
ZA (1) ZA894250B (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2581382B1 (fr) * 1985-05-06 1987-06-26 Sanofi Sa Derives n-(quinolyl) glycinamides, leur procede de preparation et leur application therapeutique en tant que psychotropes
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds

Also Published As

Publication number Publication date
FR2632305A1 (fr) 1989-12-08
ZA894250B (en) 1991-02-27

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ST Notification of lapse