CZ285829B6 - Použití derivátu tetrahydrobenz [c,d]indolu pro výrobu farmaceutického prostředku vhodného pro ošetřování sexuální dysfunkce - Google Patents

Použití derivátu tetrahydrobenz [c,d]indolu pro výrobu farmaceutického prostředku vhodného pro ošetřování sexuální dysfunkce Download PDF

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Publication number
CZ285829B6
CZ285829B6 CZ982818A CZ281898A CZ285829B6 CZ 285829 B6 CZ285829 B6 CZ 285829B6 CZ 982818 A CZ982818 A CZ 982818A CZ 281898 A CZ281898 A CZ 281898A CZ 285829 B6 CZ285829 B6 CZ 285829B6
Authority
CZ
Czechia
Prior art keywords
tetrahydrobenz
indole
carboxamide
sexual dysfunction
treatment
Prior art date
Application number
CZ982818A
Other languages
Czech (cs)
English (en)
Inventor
Mark Mortensen Foreman
David J. Leander
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of CZ285829B6 publication Critical patent/CZ285829B6/cs

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biomedical Technology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CZ982818A 1993-06-10 1994-06-02 Použití derivátu tetrahydrobenz [c,d]indolu pro výrobu farmaceutického prostředku vhodného pro ošetřování sexuální dysfunkce CZ285829B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7519893A 1993-06-10 1993-06-10

Publications (1)

Publication Number Publication Date
CZ285829B6 true CZ285829B6 (cs) 1999-11-17

Family

ID=22124191

Family Applications (2)

Application Number Title Priority Date Filing Date
CZ982818A CZ285829B6 (cs) 1993-06-10 1994-06-02 Použití derivátu tetrahydrobenz [c,d]indolu pro výrobu farmaceutického prostředku vhodného pro ošetřování sexuální dysfunkce
CZ941354A CZ285762B6 (cs) 1993-06-10 1994-06-02 Farmaceutický prostředek vhodný pro prevenci dávení a zvracení a pro ošetřování sexuální dysfunkce savců a jeho použití

Family Applications After (1)

Application Number Title Priority Date Filing Date
CZ941354A CZ285762B6 (cs) 1993-06-10 1994-06-02 Farmaceutický prostředek vhodný pro prevenci dávení a zvracení a pro ošetřování sexuální dysfunkce savců a jeho použití

Country Status (17)

Country Link
US (1) US5703112A (OSRAM)
EP (2) EP0633023A3 (OSRAM)
JP (1) JPH0748254A (OSRAM)
KR (2) KR100367792B1 (OSRAM)
CN (2) CN1072932C (OSRAM)
AU (1) AU677317B2 (OSRAM)
CA (1) CA2125088A1 (OSRAM)
CZ (2) CZ285829B6 (OSRAM)
HK (1) HK1043322B (OSRAM)
HU (1) HUT71464A (OSRAM)
IL (1) IL109872A (OSRAM)
NO (4) NO321500B1 (OSRAM)
NZ (2) NZ260667A (OSRAM)
RU (1) RU2154476C2 (OSRAM)
TW (1) TW258660B (OSRAM)
UA (2) UA29415C2 (OSRAM)
ZA (1) ZA943862B (OSRAM)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1173167A4 (en) 1999-04-30 2004-07-14 Lilly Icos Llc TREATMENT OF FEMALE SEXUAL STIMULATION DISORDERS
RU2154490C1 (ru) * 1999-07-15 2000-08-20 Кибрик Николай Давидович Способ лечения сексуальных расстройств диэнцефального генеза у мужчин
GB0106446D0 (en) * 2001-03-15 2001-05-02 Vernalis Res Ltd Chemical compounds
RU2200556C1 (ru) * 2001-12-05 2003-03-20 Северцев Владимир Алексеевич Лекарственная форма налтрексона
CA2611713C (en) 2005-06-08 2013-10-01 Sk Holdings Co., Ltd. Treatment of sleep-wake disorders
EP1893291B1 (en) * 2005-06-22 2010-03-03 SK Holdings Co., Ltd. Treatment of sexual dysfunction
BRPI1015233A2 (pt) 2009-06-22 2018-02-20 Sk Biopharmaceuticals Co Ltd métodos para tratar ou prevenir a fadiga
CN102762201B (zh) 2009-11-06 2013-12-18 爱思开生物制药株式会社 注意力缺陷/多动症的治疗方法
US8927602B2 (en) 2009-11-06 2015-01-06 Sk Biopharmaceuticals Co., Ltd. Methods for treating fibromyalgia syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
RU2689984C2 (ru) 2013-03-13 2019-05-30 ЭРИЭЛ БАЙОФАРМА, ЭлЭлСи Лечение катаплексии
KR102309836B1 (ko) 2013-07-18 2021-10-12 에스케이바이오팜 주식회사 비만의 치료
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
AU2018278332B2 (en) 2017-06-02 2022-05-19 Jazz Pharmaceuticals Ireland Limited Methods and compositions for treating excessive sleepiness
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4521421A (en) * 1983-09-26 1985-06-04 Eli Lilly And Company Treatment of sexual dysfunction
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
CA1266482A1 (en) * 1984-05-24 1990-03-06 Carl Kaiser 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
US4745126A (en) * 1987-03-12 1988-05-17 Eli Lilly And Company Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
US4943428A (en) * 1987-07-10 1990-07-24 Wright State University Stimulation of serotonin-1A receptors in mammals to alleviate motion sickness and emesis induced by chemical agents
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
CA2057912C (en) * 1989-07-13 1996-10-29 Chiu-Hong Lin (1,2n) and (3,2n)-carbocyclic-2-amino tetralin derivatives
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli 6-Substituted-hexahydrobenz (cd) indoles process for their preparation and pharmaceutical compositions containing them
CA2075057A1 (en) * 1990-03-15 1991-09-16 Pharmacia & Upjohn Company Llc Therapeutically useful heterocyclic indole compounds
US5096908A (en) * 1990-05-04 1992-03-17 Eli Lilly And Company Method of inhibiting gastric acid secretion
US5258379A (en) * 1990-05-04 1993-11-02 Eli Lilly And Company Method of inhibiting gastric acid secretion with n-arylpiperazines
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof

Also Published As

Publication number Publication date
HK1043322B (zh) 2005-06-03
NO991551L (no) 1994-12-12
NO991551D0 (no) 1999-03-30
NO20015806D0 (no) 2001-11-28
NO942143L (no) 1994-12-12
NO942143D0 (no) 1994-06-09
JPH0748254A (ja) 1995-02-21
US5703112A (en) 1997-12-30
EP1166783A3 (en) 2002-01-09
IL109872A (en) 2000-12-06
KR100367792B1 (ko) 2003-02-19
NO321500B1 (no) 2006-05-15
AU677317B2 (en) 1997-04-17
HUT71464A (en) 1995-11-28
NO993461D0 (no) 1999-07-14
KR950000146A (ko) 1995-01-03
EP1166783A2 (en) 2002-01-02
CZ135494A3 (en) 1994-12-15
KR100367791B1 (ko) 2003-02-14
UA29415C2 (uk) 2000-11-15
CN1072932C (zh) 2001-10-17
NZ260667A (en) 1997-05-26
ZA943862B (en) 1995-12-04
NZ314570A (en) 2000-11-24
CN1342457A (zh) 2002-04-03
NO993461L (no) 1994-12-12
HU9401730D0 (en) 1994-09-28
EP0633023A3 (en) 1995-03-29
EP0633023A2 (en) 1995-01-11
CA2125088A1 (en) 1994-12-11
IL109872A0 (en) 1994-10-07
UA37311C2 (uk) 2001-05-15
AU6460794A (en) 1994-12-15
CN1170536C (zh) 2004-10-13
TW258660B (OSRAM) 1995-10-01
RU2154476C2 (ru) 2000-08-20
CZ285762B6 (cs) 1999-11-17
CN1100634A (zh) 1995-03-29
NO20015806L (no) 1994-12-12
HK1043322A1 (en) 2002-09-13
NO308693B1 (no) 2000-10-16
RU94020717A (ru) 1996-08-27

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Legal Events

Date Code Title Description
IF00 In force as of 2000-06-30 in czech republic
MM4A Patent lapsed due to non-payment of fee

Effective date: 20070602