NO308693B1 - Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider for fremstilling av medikamenter for forebyggelse av emesis - Google Patents

Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider for fremstilling av medikamenter for forebyggelse av emesis

Info

Publication number
NO308693B1
NO308693B1 NO993461A NO993461A NO308693B1 NO 308693 B1 NO308693 B1 NO 308693B1 NO 993461 A NO993461 A NO 993461A NO 993461 A NO993461 A NO 993461A NO 308693 B1 NO308693 B1 NO 308693B1
Authority
NO
Norway
Prior art keywords
tetrahydrobenz
emesis
carboxamides
indole
drugs
Prior art date
Application number
NO993461A
Other languages
English (en)
Other versions
NO993461D0 (no
NO993461L (no
Inventor
Mark Mortensen Foreman
J David Leander
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO993461L publication Critical patent/NO993461L/no
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO993461D0 publication Critical patent/NO993461D0/no
Publication of NO308693B1 publication Critical patent/NO308693B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO993461A 1993-06-10 1999-07-14 Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider for fremstilling av medikamenter for forebyggelse av emesis NO308693B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7519893A 1993-06-10 1993-06-10

Publications (3)

Publication Number Publication Date
NO993461L NO993461L (no) 1994-12-12
NO993461D0 NO993461D0 (no) 1999-07-14
NO308693B1 true NO308693B1 (no) 2000-10-16

Family

ID=22124191

Family Applications (4)

Application Number Title Priority Date Filing Date
NO19942143A NO321500B1 (no) 1993-06-10 1994-06-09 Anvendelse av et tetrahydrobenz[cd]indol-6-karboksamid for fremstilling av et medikament for behandling av seksuell dysfunksjon
NO991551A NO991551D0 (no) 1993-06-10 1999-03-30 Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider i fremstilling av medikamenter for forebyggelse av emesis og behandling av seksuell dysfunksjon
NO993461A NO308693B1 (no) 1993-06-10 1999-07-14 Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider for fremstilling av medikamenter for forebyggelse av emesis
NO20015806A NO20015806D0 (no) 1993-06-10 2001-11-28 Farmasöytisk preparat inneholdende et tetrahydrobenz[c,d]indol-6-karboksamid og anvendelse derav

Family Applications Before (2)

Application Number Title Priority Date Filing Date
NO19942143A NO321500B1 (no) 1993-06-10 1994-06-09 Anvendelse av et tetrahydrobenz[cd]indol-6-karboksamid for fremstilling av et medikament for behandling av seksuell dysfunksjon
NO991551A NO991551D0 (no) 1993-06-10 1999-03-30 Anvendelse av tetrahydrobenz(cd)indol-6-karboksamider i fremstilling av medikamenter for forebyggelse av emesis og behandling av seksuell dysfunksjon

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20015806A NO20015806D0 (no) 1993-06-10 2001-11-28 Farmasöytisk preparat inneholdende et tetrahydrobenz[c,d]indol-6-karboksamid og anvendelse derav

Country Status (17)

Country Link
US (1) US5703112A (no)
EP (2) EP1166783A3 (no)
JP (1) JPH0748254A (no)
KR (2) KR100367792B1 (no)
CN (2) CN1072932C (no)
AU (1) AU677317B2 (no)
CA (1) CA2125088A1 (no)
CZ (2) CZ285762B6 (no)
HK (1) HK1043322B (no)
HU (1) HUT71464A (no)
IL (1) IL109872A (no)
NO (4) NO321500B1 (no)
NZ (2) NZ260667A (no)
RU (1) RU2154476C2 (no)
TW (1) TW258660B (no)
UA (2) UA29415C2 (no)
ZA (1) ZA943862B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4663100A (en) 1999-04-30 2000-11-17 Lilly Icos Llc Treatment of female arousal disorder
GB0106446D0 (en) * 2001-03-15 2001-05-02 Vernalis Res Ltd Chemical compounds
AU2006254899B2 (en) 2005-06-08 2011-11-24 Sk Biopharmaceuticals Co., Ltd. Treatment of sleep-wake disorders
CA2612672C (en) * 2005-06-22 2014-10-14 Janssen Pharmaceutica, N.V. Treatment for sexual dysfunction
US8741950B2 (en) 2009-06-22 2014-06-03 Sk Biopharmaceuticals Co., Ltd. Methods for treating or preventing fatigue
MX2012005258A (es) 2009-11-06 2012-06-19 Sk Biopharmaceuticals Co Ltd El uso de un compuesto de carbamoilo para el tratamiento del trastorno de deficit de atencion/hiperactividad.
AU2010316172B2 (en) 2009-11-06 2015-11-12 Sk Biopharmaceuticals Co., Ltd. Methods for treating fibromyalgia syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
DK2968208T3 (da) 2013-03-13 2022-08-22 Jazz Pharmaceuticals Ireland Ltd Behandling af kataplexi
CN110638804A (zh) 2013-07-18 2020-01-03 爵士制药国际Iii有限公司 治疗肥胖
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
KR20200016889A (ko) 2017-06-02 2020-02-17 재즈 파마슈티칼즈 아일랜드 리미티드 과다 졸림증을 치료하기 위한 방법 및 조성물
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4521421A (en) * 1983-09-26 1985-06-04 Eli Lilly And Company Treatment of sexual dysfunction
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
CA1266482A1 (en) * 1984-05-24 1990-03-06 Carl Kaiser 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
US4745126A (en) * 1987-03-12 1988-05-17 Eli Lilly And Company Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
US4943428A (en) * 1987-07-10 1990-07-24 Wright State University Stimulation of serotonin-1A receptors in mammals to alleviate motion sickness and emesis induced by chemical agents
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
KR0151699B1 (ko) * 1989-07-13 1998-10-15 로버트 에이. 아미테이지 (1,2n) 및 (3,2n)-카보사이클릭-2-아미노테트랄린 유도체
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli Xahydrobenz [DC] Induced indoles in position 6, their preparation process and pharmaceutical preparations containing them
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
WO1991013872A1 (en) * 1990-03-15 1991-09-19 The Upjohn Company Therapeutically useful heterocyclic indole compounds
US5258379A (en) * 1990-05-04 1993-11-02 Eli Lilly And Company Method of inhibiting gastric acid secretion with n-arylpiperazines
US5096908A (en) * 1990-05-04 1992-03-17 Eli Lilly And Company Method of inhibiting gastric acid secretion
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof

Also Published As

Publication number Publication date
NO20015806L (no) 1994-12-12
CN1072932C (zh) 2001-10-17
KR950000146A (ko) 1995-01-03
CZ285829B6 (cs) 1999-11-17
EP0633023A2 (en) 1995-01-11
UA37311C2 (uk) 2001-05-15
NO991551L (no) 1994-12-12
HU9401730D0 (en) 1994-09-28
RU94020717A (ru) 1996-08-27
CZ135494A3 (en) 1994-12-15
CN1342457A (zh) 2002-04-03
NO991551D0 (no) 1999-03-30
RU2154476C2 (ru) 2000-08-20
ZA943862B (en) 1995-12-04
JPH0748254A (ja) 1995-02-21
EP1166783A3 (en) 2002-01-09
IL109872A0 (en) 1994-10-07
NO321500B1 (no) 2006-05-15
NO20015806D0 (no) 2001-11-28
AU6460794A (en) 1994-12-15
CN1170536C (zh) 2004-10-13
CZ285762B6 (cs) 1999-11-17
EP1166783A2 (en) 2002-01-02
IL109872A (en) 2000-12-06
NZ314570A (en) 2000-11-24
US5703112A (en) 1997-12-30
HK1043322A1 (en) 2002-09-13
AU677317B2 (en) 1997-04-17
NO942143L (no) 1994-12-12
EP0633023A3 (en) 1995-03-29
NZ260667A (en) 1997-05-26
HUT71464A (en) 1995-11-28
KR100367792B1 (ko) 2003-02-19
KR100367791B1 (ko) 2003-02-14
NO993461D0 (no) 1999-07-14
CN1100634A (zh) 1995-03-29
NO942143D0 (no) 1994-06-09
HK1043322B (zh) 2005-06-03
TW258660B (no) 1995-10-01
UA29415C2 (uk) 2000-11-15
NO993461L (no) 1994-12-12
CA2125088A1 (en) 1994-12-11

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