HK1043322B - 四氫苯並[cd]吲-6-甲酰胺類化合物在製備用於預防嘔吐的藥物中的用途 - Google Patents

四氫苯並[cd]吲-6-甲酰胺類化合物在製備用於預防嘔吐的藥物中的用途

Info

Publication number
HK1043322B
HK1043322B HK02105194.1A HK02105194A HK1043322B HK 1043322 B HK1043322 B HK 1043322B HK 02105194 A HK02105194 A HK 02105194A HK 1043322 B HK1043322 B HK 1043322B
Authority
HK
Hong Kong
Prior art keywords
tetrahydrobenz
carboxamides
indole
drug
preparing
Prior art date
Application number
HK02105194.1A
Other languages
English (en)
Other versions
HK1043322A1 (en
Inventor
Mortensen Foreman Mark
David Leander J
Original Assignee
伊萊利利公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 伊萊利利公司 filed Critical 伊萊利利公司
Publication of HK1043322A1 publication Critical patent/HK1043322A1/xx
Publication of HK1043322B publication Critical patent/HK1043322B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK02105194.1A 1993-06-10 2002-07-12 四氫苯並[cd]吲-6-甲酰胺類化合物在製備用於預防嘔吐的藥物中的用途 HK1043322B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7519893A 1993-06-10 1993-06-10

Publications (2)

Publication Number Publication Date
HK1043322A1 HK1043322A1 (en) 2002-09-13
HK1043322B true HK1043322B (zh) 2005-06-03

Family

ID=22124191

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02105194.1A HK1043322B (zh) 1993-06-10 2002-07-12 四氫苯並[cd]吲-6-甲酰胺類化合物在製備用於預防嘔吐的藥物中的用途

Country Status (17)

Country Link
US (1) US5703112A (zh)
EP (2) EP1166783A3 (zh)
JP (1) JPH0748254A (zh)
KR (2) KR100367792B1 (zh)
CN (2) CN1072932C (zh)
AU (1) AU677317B2 (zh)
CA (1) CA2125088A1 (zh)
CZ (2) CZ285762B6 (zh)
HK (1) HK1043322B (zh)
HU (1) HUT71464A (zh)
IL (1) IL109872A (zh)
NO (4) NO321500B1 (zh)
NZ (2) NZ260667A (zh)
RU (1) RU2154476C2 (zh)
TW (1) TW258660B (zh)
UA (2) UA29415C2 (zh)
ZA (1) ZA943862B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4663100A (en) 1999-04-30 2000-11-17 Lilly Icos Llc Treatment of female arousal disorder
GB0106446D0 (en) * 2001-03-15 2001-05-02 Vernalis Res Ltd Chemical compounds
AU2006254899B2 (en) 2005-06-08 2011-11-24 Sk Biopharmaceuticals Co., Ltd. Treatment of sleep-wake disorders
CA2612672C (en) * 2005-06-22 2014-10-14 Janssen Pharmaceutica, N.V. Treatment for sexual dysfunction
US8741950B2 (en) 2009-06-22 2014-06-03 Sk Biopharmaceuticals Co., Ltd. Methods for treating or preventing fatigue
MX2012005258A (es) 2009-11-06 2012-06-19 Sk Biopharmaceuticals Co Ltd El uso de un compuesto de carbamoilo para el tratamiento del trastorno de deficit de atencion/hiperactividad.
AU2010316172B2 (en) 2009-11-06 2015-11-12 Sk Biopharmaceuticals Co., Ltd. Methods for treating fibromyalgia syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
DK2968208T3 (da) 2013-03-13 2022-08-22 Jazz Pharmaceuticals Ireland Ltd Behandling af kataplexi
CN110638804A (zh) 2013-07-18 2020-01-03 爵士制药国际Iii有限公司 治疗肥胖
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
KR20200016889A (ko) 2017-06-02 2020-02-17 재즈 파마슈티칼즈 아일랜드 리미티드 과다 졸림증을 치료하기 위한 방법 및 조성물
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4521421A (en) * 1983-09-26 1985-06-04 Eli Lilly And Company Treatment of sexual dysfunction
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
CA1266482A1 (en) * 1984-05-24 1990-03-06 Carl Kaiser 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
US4745126A (en) * 1987-03-12 1988-05-17 Eli Lilly And Company Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
US4943428A (en) * 1987-07-10 1990-07-24 Wright State University Stimulation of serotonin-1A receptors in mammals to alleviate motion sickness and emesis induced by chemical agents
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
KR0151699B1 (ko) * 1989-07-13 1998-10-15 로버트 에이. 아미테이지 (1,2n) 및 (3,2n)-카보사이클릭-2-아미노테트랄린 유도체
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli Xahydrobenz [DC] Induced indoles in position 6, their preparation process and pharmaceutical preparations containing them
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
WO1991013872A1 (en) * 1990-03-15 1991-09-19 The Upjohn Company Therapeutically useful heterocyclic indole compounds
US5258379A (en) * 1990-05-04 1993-11-02 Eli Lilly And Company Method of inhibiting gastric acid secretion with n-arylpiperazines
US5096908A (en) * 1990-05-04 1992-03-17 Eli Lilly And Company Method of inhibiting gastric acid secretion
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof

Also Published As

Publication number Publication date
NO20015806L (no) 1994-12-12
CN1072932C (zh) 2001-10-17
KR950000146A (ko) 1995-01-03
CZ285829B6 (cs) 1999-11-17
EP0633023A2 (en) 1995-01-11
UA37311C2 (uk) 2001-05-15
NO991551L (no) 1994-12-12
HU9401730D0 (en) 1994-09-28
RU94020717A (ru) 1996-08-27
CZ135494A3 (en) 1994-12-15
CN1342457A (zh) 2002-04-03
NO991551D0 (no) 1999-03-30
RU2154476C2 (ru) 2000-08-20
ZA943862B (en) 1995-12-04
JPH0748254A (ja) 1995-02-21
EP1166783A3 (en) 2002-01-09
IL109872A0 (en) 1994-10-07
NO308693B1 (no) 2000-10-16
NO321500B1 (no) 2006-05-15
NO20015806D0 (no) 2001-11-28
AU6460794A (en) 1994-12-15
CN1170536C (zh) 2004-10-13
CZ285762B6 (cs) 1999-11-17
EP1166783A2 (en) 2002-01-02
IL109872A (en) 2000-12-06
NZ314570A (en) 2000-11-24
US5703112A (en) 1997-12-30
HK1043322A1 (en) 2002-09-13
AU677317B2 (en) 1997-04-17
NO942143L (no) 1994-12-12
EP0633023A3 (en) 1995-03-29
NZ260667A (en) 1997-05-26
HUT71464A (en) 1995-11-28
KR100367792B1 (ko) 2003-02-19
KR100367791B1 (ko) 2003-02-14
NO993461D0 (no) 1999-07-14
CN1100634A (zh) 1995-03-29
NO942143D0 (no) 1994-06-09
TW258660B (zh) 1995-10-01
UA29415C2 (uk) 2000-11-15
NO993461L (no) 1994-12-12
CA2125088A1 (en) 1994-12-11

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080609