RU94020717A - Применение тетрагидробенз[cd]индол-6-карбоксамидов для предотвращения рвоты и лечения половой дисфункции, фармацевтические препараты на их основе - Google Patents

Применение тетрагидробенз[cd]индол-6-карбоксамидов для предотвращения рвоты и лечения половой дисфункции, фармацевтические препараты на их основе

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Publication number
RU94020717A
RU94020717A RU94020717/14A RU94020717A RU94020717A RU 94020717 A RU94020717 A RU 94020717A RU 94020717/14 A RU94020717/14 A RU 94020717/14A RU 94020717 A RU94020717 A RU 94020717A RU 94020717 A RU94020717 A RU 94020717A
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RU
Russia
Prior art keywords
tetrahydrobenz
carboxamides
indole
pharmaceutical preparations
sexual dysfunction
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Application number
RU94020717/14A
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English (en)
Other versions
RU2154476C2 (ru
Inventor
Мортенсен Формен Марк
Us]
Линдер Дж.Дэвид
Original Assignee
Эли Лилли энд Компани (US)
Эли Лилли Энд Компани
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Application filed by Эли Лилли энд Компани (US), Эли Лилли Энд Компани filed Critical Эли Лилли энд Компани (US)
Publication of RU94020717A publication Critical patent/RU94020717A/ru
Application granted granted Critical
Publication of RU2154476C2 publication Critical patent/RU2154476C2/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Предлагаемое изобретение предусматривает способы предотвращения рвоты и лечения половой дисфункции у млекопитающих с использованием некоторых тетрагидробенз [cd] индолов. Изобретение также предлагает фармацевтические препараты, пригодные для использования в таких способах лечения.

Claims (1)

  1. Предлагаемое изобретение предусматривает способы предотвращения рвоты и лечения половой дисфункции у млекопитающих с использованием некоторых тетрагидробенз [cd] индолов. Изобретение также предлагает фармацевтические препараты, пригодные для использования в таких способах лечения.
RU94020717/14A 1993-06-10 1994-06-09 ПРИМЕНЕНИЕ ТЕТРАГИДРОБЕНЗ /cd/ИНДОЛ-6-КАРБОКСАМИДОВ ДЛЯ ПРЕДОТВРАЩЕНИЯ РВОТЫ, ФАРМАЦЕВТИЧЕСКИЕ ПРЕПАРАТЫ НА ИХ ОСНОВЕ RU2154476C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7519893A 1993-06-10 1993-06-10
US08/075,198 1993-06-10

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU99117174/14A Division RU99117174A (ru) 1993-06-10 1999-08-05 Применение тетрагидробенз [cd] индол-6-карбоксамидов для лечения половой дисфункции, фармацевтическая композиция

Publications (2)

Publication Number Publication Date
RU94020717A true RU94020717A (ru) 1996-08-27
RU2154476C2 RU2154476C2 (ru) 2000-08-20

Family

ID=22124191

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94020717/14A RU2154476C2 (ru) 1993-06-10 1994-06-09 ПРИМЕНЕНИЕ ТЕТРАГИДРОБЕНЗ /cd/ИНДОЛ-6-КАРБОКСАМИДОВ ДЛЯ ПРЕДОТВРАЩЕНИЯ РВОТЫ, ФАРМАЦЕВТИЧЕСКИЕ ПРЕПАРАТЫ НА ИХ ОСНОВЕ

Country Status (17)

Country Link
US (1) US5703112A (ru)
EP (2) EP1166783A3 (ru)
JP (1) JPH0748254A (ru)
KR (2) KR100367792B1 (ru)
CN (2) CN1072932C (ru)
AU (1) AU677317B2 (ru)
CA (1) CA2125088A1 (ru)
CZ (2) CZ285762B6 (ru)
HK (1) HK1043322B (ru)
HU (1) HUT71464A (ru)
IL (1) IL109872A (ru)
NO (4) NO321500B1 (ru)
NZ (2) NZ260667A (ru)
RU (1) RU2154476C2 (ru)
TW (1) TW258660B (ru)
UA (2) UA29415C2 (ru)
ZA (1) ZA943862B (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4663100A (en) 1999-04-30 2000-11-17 Lilly Icos Llc Treatment of female arousal disorder
GB0106446D0 (en) * 2001-03-15 2001-05-02 Vernalis Res Ltd Chemical compounds
AU2006254899B2 (en) 2005-06-08 2011-11-24 Sk Biopharmaceuticals Co., Ltd. Treatment of sleep-wake disorders
CA2612672C (en) * 2005-06-22 2014-10-14 Janssen Pharmaceutica, N.V. Treatment for sexual dysfunction
US8741950B2 (en) 2009-06-22 2014-06-03 Sk Biopharmaceuticals Co., Ltd. Methods for treating or preventing fatigue
MX2012005258A (es) 2009-11-06 2012-06-19 Sk Biopharmaceuticals Co Ltd El uso de un compuesto de carbamoilo para el tratamiento del trastorno de deficit de atencion/hiperactividad.
AU2010316172B2 (en) 2009-11-06 2015-11-12 Sk Biopharmaceuticals Co., Ltd. Methods for treating fibromyalgia syndrome
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
DK2968208T3 (da) 2013-03-13 2022-08-22 Jazz Pharmaceuticals Ireland Ltd Behandling af kataplexi
CN110638804A (zh) 2013-07-18 2020-01-03 爵士制药国际Iii有限公司 治疗肥胖
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
KR20200016889A (ko) 2017-06-02 2020-02-17 재즈 파마슈티칼즈 아일랜드 리미티드 과다 졸림증을 치료하기 위한 방법 및 조성물
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

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US4521421A (en) * 1983-09-26 1985-06-04 Eli Lilly And Company Treatment of sexual dysfunction
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
CA1266482A1 (en) * 1984-05-24 1990-03-06 Carl Kaiser 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
US4745126A (en) * 1987-03-12 1988-05-17 Eli Lilly And Company Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
US4943428A (en) * 1987-07-10 1990-07-24 Wright State University Stimulation of serotonin-1A receptors in mammals to alleviate motion sickness and emesis induced by chemical agents
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
KR0151699B1 (ko) * 1989-07-13 1998-10-15 로버트 에이. 아미테이지 (1,2n) 및 (3,2n)-카보사이클릭-2-아미노테트랄린 유도체
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli Xahydrobenz [DC] Induced indoles in position 6, their preparation process and pharmaceutical preparations containing them
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
WO1991013872A1 (en) * 1990-03-15 1991-09-19 The Upjohn Company Therapeutically useful heterocyclic indole compounds
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Also Published As

Publication number Publication date
NO20015806L (no) 1994-12-12
CN1072932C (zh) 2001-10-17
KR950000146A (ko) 1995-01-03
CZ285829B6 (cs) 1999-11-17
EP0633023A2 (en) 1995-01-11
UA37311C2 (ru) 2001-05-15
NO991551L (no) 1994-12-12
HU9401730D0 (en) 1994-09-28
CZ135494A3 (en) 1994-12-15
CN1342457A (zh) 2002-04-03
NO991551D0 (no) 1999-03-30
RU2154476C2 (ru) 2000-08-20
ZA943862B (en) 1995-12-04
JPH0748254A (ja) 1995-02-21
EP1166783A3 (en) 2002-01-09
IL109872A0 (en) 1994-10-07
NO308693B1 (no) 2000-10-16
NO321500B1 (no) 2006-05-15
NO20015806D0 (no) 2001-11-28
AU6460794A (en) 1994-12-15
CN1170536C (zh) 2004-10-13
CZ285762B6 (cs) 1999-11-17
EP1166783A2 (en) 2002-01-02
IL109872A (en) 2000-12-06
NZ314570A (en) 2000-11-24
US5703112A (en) 1997-12-30
HK1043322A1 (en) 2002-09-13
AU677317B2 (en) 1997-04-17
NO942143L (no) 1994-12-12
EP0633023A3 (en) 1995-03-29
NZ260667A (en) 1997-05-26
HUT71464A (en) 1995-11-28
KR100367792B1 (ko) 2003-02-19
KR100367791B1 (ko) 2003-02-14
NO993461D0 (no) 1999-07-14
CN1100634A (zh) 1995-03-29
NO942143D0 (no) 1994-06-09
HK1043322B (zh) 2005-06-03
TW258660B (ru) 1995-10-01
UA29415C2 (ru) 2000-11-15
NO993461L (no) 1994-12-12
CA2125088A1 (en) 1994-12-11

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Effective date: 20070610