ATE222769T1 - Verabreichung von gm-csf zur behandlung der gehirntumoren und verhütung deren wiederauftretens - Google Patents
Verabreichung von gm-csf zur behandlung der gehirntumoren und verhütung deren wiederauftretensInfo
- Publication number
- ATE222769T1 ATE222769T1 AT97930090T AT97930090T ATE222769T1 AT E222769 T1 ATE222769 T1 AT E222769T1 AT 97930090 T AT97930090 T AT 97930090T AT 97930090 T AT97930090 T AT 97930090T AT E222769 T1 ATE222769 T1 AT E222769T1
- Authority
- AT
- Austria
- Prior art keywords
- csf
- administration
- recurrence
- prevent
- brain tumors
- Prior art date
Links
- 208000003174 Brain Neoplasms Diseases 0.000 title abstract 3
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 title abstract 2
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5152—Tumor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/671,251 US5837231A (en) | 1996-06-27 | 1996-06-27 | GM-CSF administration for the treatment and prevention of recurrence of brain tumors |
PCT/US1997/010540 WO1997049421A1 (en) | 1996-06-27 | 1997-06-18 | Gm-csf administration for the treatment and prevention of recurrence of brain tumors |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE222769T1 true ATE222769T1 (de) | 2002-09-15 |
Family
ID=24693739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97930090T ATE222769T1 (de) | 1996-06-27 | 1997-06-18 | Verabreichung von gm-csf zur behandlung der gehirntumoren und verhütung deren wiederauftretens |
Country Status (9)
Country | Link |
---|---|
US (1) | US5837231A (de) |
EP (1) | EP0912192B1 (de) |
JP (1) | JP2000515127A (de) |
AT (1) | ATE222769T1 (de) |
AU (1) | AU3400297A (de) |
CA (1) | CA2258608A1 (de) |
DE (1) | DE69715000T2 (de) |
DK (1) | DK0912192T3 (de) |
WO (1) | WO1997049421A1 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6977074B2 (en) * | 1997-07-10 | 2005-12-20 | Mannkind Corporation | Method of inducing a CTL response |
AU1628599A (en) * | 1997-12-05 | 1999-06-28 | Medical College Of Georgia Research Institute, Inc. | Regulation of t cell-mediated immunity by tryptophan |
JP5546084B2 (ja) * | 1998-05-26 | 2014-07-09 | オプサニテクス エルエルシー | 抗原に対する免疫応答を調節する組成物および方法 |
AU5458500A (en) * | 1999-06-02 | 2000-12-18 | Cell Genesys, Inc. | Regulation of systemic immune responses utilizing cytokines and antigens |
ATE371017T1 (de) * | 2000-09-15 | 2007-09-15 | Ortho Mcneil Pharm Inc | Zusammensetzungen und verfahren zur auslösung spezifischer zytolytischer t-zellantworten |
CA2441434A1 (en) * | 2001-03-12 | 2002-09-19 | Institute Of Gene And Brain Science | Remedies for nerve damages |
US7388079B2 (en) * | 2002-11-27 | 2008-06-17 | The Regents Of The University Of California | Delivery of pharmaceutical agents via the human insulin receptor |
US7695723B2 (en) * | 2002-12-31 | 2010-04-13 | Sygnis Bioscience Gmbh & Co. Kg | Methods of treating neurological conditions with hematopoietic growth factors |
US7598287B2 (en) | 2003-04-01 | 2009-10-06 | Medical College Of Georgia Research Institute, Inc. | Use of inhibitors of indoleamine-2,3-dioxygenase in combination with other therapeutic modalities |
US20050186289A1 (en) * | 2003-04-01 | 2005-08-25 | Medical College Of Georgia Research Institute, Inc. | Regulation of T cell-mediated immunity by D isomers of inhibitors of indoleamine-2,3-dioxygenase |
US20060234941A1 (en) | 2005-04-15 | 2006-10-19 | The Gov. Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services | Peptide epitopes of VEGFR-2/KDR that inhibit angiogenesis |
US8142781B2 (en) * | 2005-10-07 | 2012-03-27 | Armagen Technologies, Inc. | Fusion proteins for blood-brain barrier delivery |
US8124095B2 (en) * | 2005-10-07 | 2012-02-28 | Armagen Technologies, Inc. | Fusion proteins for delivery of erythropoietin to the CNS |
US8741260B2 (en) * | 2005-10-07 | 2014-06-03 | Armagen Technologies, Inc. | Fusion proteins for delivery of GDNF to the CNS |
WO2007081878A2 (en) * | 2006-01-07 | 2007-07-19 | Medical College Of Georgia Research Institute, Inc. | Indoleamine 2,3-dioxygenase pathways in the generation of regulatory t cells |
CA2661042C (en) | 2006-08-18 | 2012-12-11 | Armagen Technologies, Inc. | Agents for blood-brain barrier delivery |
WO2008137066A1 (en) * | 2007-05-02 | 2008-11-13 | The Board Of Regents Of The University Of Oklahoma | Use of compacted nucleic acid nanoparticles in non-viral treatments of ocular diseases |
JP5901877B2 (ja) * | 2007-07-27 | 2016-04-13 | アーメイゲン・テクノロジーズ・インコーポレイテッドArmagen Technologies, Inc. | 中枢神経系のα−L−イデュロニダーゼ活性を増加させるための方法および組成物 |
JP5873003B2 (ja) | 2009-03-18 | 2016-03-01 | アーメイゲン・テクノロジーズ・インコーポレイテッドArmagen Technologies, Inc. | IgGデコイ受容体融合タンパク質の血液脳関門送達のための組成物および方法 |
WO2011044542A1 (en) | 2009-10-09 | 2011-04-14 | Armagen Technologies, Inc. | Methods and compositions for increasing iduronate 2-sulfatase activity in the cns |
JP6426001B2 (ja) * | 2011-11-17 | 2018-11-21 | グリア エスピー ゼット.オー.オー. | 神経膠腫を治療するための組成物および方法 |
WO2013078392A1 (en) * | 2011-11-21 | 2013-05-30 | The University Of Chicago | Methods and compositions involving induced senescent cells for cancer treatment |
EP2785378B1 (de) | 2011-12-02 | 2020-05-13 | Armagen, Inc. | Verfahren und zusammensetzungen für erhöhte sulfatase-a-aktivität im zns |
PT3536334T (pt) | 2012-05-16 | 2021-09-27 | Stemline Therapeutics Inc | Vacinas contra o cancro dirigidas a células estaminais cancerígenas |
US10538589B2 (en) | 2015-01-14 | 2020-01-21 | Armagen Inc. | Methods and compositions for increasing N-acetylglucosaminidase (NAGLU) activity in the CNS using a fusion antibody comprising an anti-human insulin receptor antibody and NAGLU |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5833975A (en) * | 1989-03-08 | 1998-11-10 | Virogenetics Corporation | Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence |
US5208022A (en) * | 1988-05-19 | 1993-05-04 | State University Of New York (Suny) | Non-malignant cells coupled to adjuvants and their use in a method to induce anti-tumor immunity |
US5165922A (en) * | 1990-05-22 | 1992-11-24 | Bristol-Myers Squibb Company | Synergistic tumor therapy with combinations of biologically active anti-tumor antibodies and chemotherapy |
AU677165B2 (en) * | 1991-10-04 | 1997-04-17 | Johns Hopkins University School Of Medicine, The | The regulation of systemic immune responses utilizing cytokines and antigens |
-
1996
- 1996-06-27 US US08/671,251 patent/US5837231A/en not_active Expired - Lifetime
-
1997
- 1997-06-18 JP JP10503283A patent/JP2000515127A/ja active Pending
- 1997-06-18 DE DE69715000T patent/DE69715000T2/de not_active Expired - Lifetime
- 1997-06-18 DK DK97930090T patent/DK0912192T3/da active
- 1997-06-18 AT AT97930090T patent/ATE222769T1/de not_active IP Right Cessation
- 1997-06-18 WO PCT/US1997/010540 patent/WO1997049421A1/en active IP Right Grant
- 1997-06-18 EP EP97930090A patent/EP0912192B1/de not_active Expired - Lifetime
- 1997-06-18 CA CA002258608A patent/CA2258608A1/en not_active Abandoned
- 1997-06-18 AU AU34002/97A patent/AU3400297A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0912192A1 (de) | 1999-05-06 |
DK0912192T3 (da) | 2002-12-02 |
DE69715000T2 (de) | 2003-01-02 |
US5837231A (en) | 1998-11-17 |
CA2258608A1 (en) | 1997-12-31 |
DE69715000D1 (de) | 2002-10-02 |
WO1997049421A1 (en) | 1997-12-31 |
JP2000515127A (ja) | 2000-11-14 |
AU3400297A (en) | 1998-01-14 |
EP0912192B1 (de) | 2002-08-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |