CY2004003I2 - Παραγωγα 2-(2-αμινο-1, 6-διϋδρο-6-οξο-πυρινο-9-υλο)-μεθοδυ-1,3-προπανεδιολης - Google Patents

Παραγωγα 2-(2-αμινο-1, 6-διϋδρο-6-οξο-πυρινο-9-υλο)-μεθοδυ-1,3-προπανεδιολης

Info

Publication number
CY2004003I2
CY2004003I2 CY200400003C CY2004003C CY2004003I2 CY 2004003 I2 CY2004003 I2 CY 2004003I2 CY 200400003 C CY200400003 C CY 200400003C CY 2004003 C CY2004003 C CY 2004003C CY 2004003 I2 CY2004003 I2 CY 2004003I2
Authority
CY
Cyprus
Prior art keywords
pyrino
methody
dihydro
oxo
amino
Prior art date
Application number
CY200400003C
Other languages
English (en)
Other versions
CY2004003I1 (el
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23079211&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2004003(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of CY2004003I1 publication Critical patent/CY2004003I1/el
Publication of CY2004003I2 publication Critical patent/CY2004003I2/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
CY200400003C 1994-07-28 2004-10-20 Παραγωγα 2-(2-αμινο-1, 6-διϋδρο-6-οξο-πυρινο-9-υλο)-μεθοδυ-1,3-προπανεδιολης CY2004003I2 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28189394A 1994-07-28 1994-07-28

Publications (2)

Publication Number Publication Date
CY2004003I1 CY2004003I1 (el) 2009-11-04
CY2004003I2 true CY2004003I2 (el) 2009-11-04

Family

ID=23079211

Family Applications (2)

Application Number Title Priority Date Filing Date
CY0000039A CY2180B1 (en) 1994-07-28 2000-08-10 2-(2Amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
CY200400003C CY2004003I2 (el) 1994-07-28 2004-10-20 Παραγωγα 2-(2-αμινο-1, 6-διϋδρο-6-οξο-πυρινο-9-υλο)-μεθοδυ-1,3-προπανεδιολης

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY0000039A CY2180B1 (en) 1994-07-28 2000-08-10 2-(2Amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative

Country Status (32)

Country Link
EP (1) EP0694547B1 (el)
JP (1) JP3090305B2 (el)
KR (1) KR100358626B1 (el)
CN (1) CN1045089C (el)
AT (1) ATE179173T1 (el)
AU (1) AU697107B2 (el)
BR (1) BR9503468A (el)
CA (1) CA2154721C (el)
CO (1) CO4410181A1 (el)
CY (2) CY2180B1 (el)
CZ (1) CZ290511B6 (el)
DE (3) DE69509173T2 (el)
DK (1) DK0694547T3 (el)
ES (1) ES2083348T3 (el)
FI (1) FI112080B (el)
GR (2) GR960300021T1 (el)
HU (1) HU216867B (el)
IL (1) IL114735A (el)
LU (1) LU91136I2 (el)
MA (1) MA23631A1 (el)
MY (1) MY114393A (el)
NL (1) NL300071I2 (el)
NO (2) NO312899B1 (el)
NZ (1) NZ272652A (el)
PE (1) PE32296A1 (el)
PL (1) PL180609B1 (el)
RU (1) RU2133749C1 (el)
SA (1) SA95160158B1 (el)
TR (1) TR199500895A2 (el)
TW (1) TW434242B (el)
UY (1) UY24006A1 (el)
ZA (1) ZA956228B (el)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458772B1 (en) 1909-10-07 2002-10-01 Medivir Ab Prodrugs
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
CN1064683C (zh) * 1996-01-26 2001-04-18 弗·哈夫曼-拉罗切有限公司 制备嘌呤衍生物的方法
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
AU1592897A (en) * 1996-01-26 1997-08-20 F. Hoffmann-La Roche Ag Process for preparing purine derivatives
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
US5869493A (en) * 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
JP4425352B2 (ja) * 1997-02-10 2010-03-03 メディヴィル・アクチボラグ 非環状ヌクレオシド誘導体の合成
US6184376B1 (en) 1997-02-10 2001-02-06 Mediver Ab Synthesis of acyclic nucleoside derivatives
ES2239637T3 (es) * 1997-08-15 2005-10-01 Medivir Ab Derivados de guanosina 3'-fluorados para el tratamiento o profilaxis de vhb o infecciones retrovirales.
AU1711599A (en) * 1997-12-19 1999-07-12 Bristol-Myers Squibb Company Prodrugs of lobucavir and methods of use
WO1999051613A1 (en) * 1998-04-03 1999-10-14 Medivir Ab Prodrugs of phosphorous-containing pharmaceuticals
JP2000256359A (ja) * 1999-03-11 2000-09-19 Japan Science & Technology Corp 面性キラリティーを有する分子群の高選択的不斉変換法
KR20030015655A (ko) * 2001-08-17 2003-02-25 한미약품공업 주식회사 항암제의 경구흡수율을 증가시키는 인단계 화합물의결정성 산부가염, 이의 제조방법 및 이를 함유하는 약학적조성물
ATE438621T1 (de) * 2002-04-23 2009-08-15 Aventis Pharma Inc 3-(substitutierte amino)-1h-indole-2- carbonsäureester und 3-(substitutierte amino)- benzoäbüthiophen-2-carbonsäureester verbindungen als inhibitoren der interleukin-4 genexpression
US8697094B2 (en) 2002-10-16 2014-04-15 Takeda Pharmaceutical Company Limited Stable solid preparations
HRP20140379A2 (hr) 2003-01-14 2014-07-18 Gilead Sciences, Inc. Pripravci i metode za kombiniranu antivirusnu terapiju
WO2005021549A1 (en) * 2003-08-28 2005-03-10 Ranbaxy Laboratories Limited Amorphous valganciclovir hydrochloride
JP5563735B2 (ja) 2004-06-16 2014-07-30 タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド Ｐｐｉ多回剤形
PL2626368T3 (pl) * 2004-07-19 2017-06-30 Biocon Limited Koniugaty insulina-oligomer, ich formulacje i zastosowania
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
ZA200702234B (en) * 2006-03-21 2008-07-30 Cipla Ltd Preparation of ester of purine derivatives
RU2010119041A (ru) 2007-10-12 2011-11-20 Такеда Фармасьютикалз Норт Америка, Инк. (Us) Способы лечения нарушений желудочно-кишечного тракта, независимого от потребления пищи
EP2714691B1 (en) * 2011-05-31 2016-09-07 Pharmathen S.A. Process for the preparation of 2-amino-9-((2-phenyl-1,3-dioxan-5-yloxy)methyl)-1h-purin-6(9h)-one compound useful in the preparation of valganciclovir
KR102312533B1 (ko) 2021-02-24 2021-10-15 주식회사 이웅 자동 스패너

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
US4897479A (en) * 1983-09-30 1990-01-30 Merck & Co., Inc. Arylsulfonyloxy purine intermediates
IE842642L (en) * 1983-10-31 1985-04-30 Harvard College Purine Derivatives
DE3583858D1 (de) * 1984-12-12 1991-09-26 Syntex Inc Derivate von alcoxymethylaether und alcoxymethylester.
AP55A (en) * 1987-08-15 1989-09-26 The Wellcome Foundation Ltd Therapeutic Acyclic Nucleosides
CA2005815C (en) * 1988-12-19 1999-08-03 Wellcome Foundation Limited (The) Antiviral acyclic nucleoside derivatives

Also Published As

Publication number Publication date
CN1045089C (zh) 1999-09-15
TR199500895A2 (tr) 1996-06-21
CY2004003I1 (el) 2009-11-04
MY114393A (en) 2002-10-31
NO312899B1 (no) 2002-07-15
ZA956228B (en) 1996-02-22
EP0694547A2 (en) 1996-01-31
PL180609B1 (pl) 2001-03-30
KR100358626B1 (ko) 2003-01-14
AU697107B2 (en) 1998-09-24
HUT73246A (en) 1996-07-29
HU216867B (hu) 1999-09-28
AU2719595A (en) 1996-02-08
CA2154721C (en) 2001-01-02
NO952977L (no) 1996-01-29
GR3030678T3 (en) 1999-11-30
SA95160158B1 (ar) 2006-05-20
ATE179173T1 (de) 1999-05-15
HU9502238D0 (en) 1995-09-28
PE32296A1 (es) 1996-08-07
DK0694547T3 (da) 2000-01-03
NZ272652A (en) 1996-12-20
KR960004345A (ko) 1996-02-23
IL114735A (en) 1998-06-15
FI953592L (fi) 1996-01-29
ES2083348T3 (es) 1999-08-01
CY2180B1 (en) 2002-08-23
CZ193995A3 (en) 1996-02-14
NL300071I1 (nl) 2002-02-01
UY24006A1 (es) 2001-07-31
JP3090305B2 (ja) 2000-09-18
IL114735A0 (en) 1995-11-27
DE10299032I2 (de) 2006-06-14
LU91136I2 (fr) 2005-07-06
NO952977D0 (no) 1995-07-27
TW434242B (en) 2001-05-16
CN1122804A (zh) 1996-05-22
GR960300021T1 (en) 1996-04-30
FI953592A0 (fi) 1995-07-27
CZ290511B6 (cs) 2002-08-14
JPH0841061A (ja) 1996-02-13
HK1012339A1 (en) 1999-07-30
CA2154721A1 (en) 1996-01-29
BR9503468A (pt) 1996-02-27
DE694547T1 (de) 1996-10-24
DE69509173D1 (de) 1999-05-27
CO4410181A1 (es) 1997-01-09
FI112080B (fi) 2003-10-31
NO2003001I2 (no) 2007-06-11
EP0694547A3 (en) 1996-06-05
ES2083348T1 (es) 1996-04-16
PL309812A1 (en) 1996-02-05
MA23631A1 (fr) 1996-04-01
DE69509173T2 (de) 1999-10-21
NL300071I2 (nl) 2002-03-01
RU2133749C1 (ru) 1999-07-27
RU95113148A (ru) 1997-06-27
DE10299032I1 (de) 2003-01-23
EP0694547B1 (en) 1999-04-21

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