DK0694547T3 - 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propandiolderivat - Google Patents

2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propandiolderivat

Info

Publication number
DK0694547T3
DK0694547T3 DK95111319T DK95111319T DK0694547T3 DK 0694547 T3 DK0694547 T3 DK 0694547T3 DK 95111319 T DK95111319 T DK 95111319T DK 95111319 T DK95111319 T DK 95111319T DK 0694547 T3 DK0694547 T3 DK 0694547T3
Authority
DK
Denmark
Prior art keywords
purin
dihydro
oxo
methoxy
amino
Prior art date
Application number
DK95111319T
Other languages
English (en)
Inventor
Scott W Womble
John J Nestor
Hans Maag
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23079211&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0694547(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0694547T3 publication Critical patent/DK0694547T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
DK95111319T 1994-07-28 1995-07-19 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propandiolderivat DK0694547T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28189394A 1994-07-28 1994-07-28

Publications (1)

Publication Number Publication Date
DK0694547T3 true DK0694547T3 (da) 2000-01-03

Family

ID=23079211

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95111319T DK0694547T3 (da) 1994-07-28 1995-07-19 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propandiolderivat

Country Status (33)

Country Link
EP (1) EP0694547B1 (da)
JP (1) JP3090305B2 (da)
KR (1) KR100358626B1 (da)
CN (1) CN1045089C (da)
AT (1) ATE179173T1 (da)
AU (1) AU697107B2 (da)
BR (1) BR9503468A (da)
CA (1) CA2154721C (da)
CO (1) CO4410181A1 (da)
CY (2) CY2180B1 (da)
CZ (1) CZ290511B6 (da)
DE (3) DE69509173T2 (da)
DK (1) DK0694547T3 (da)
ES (1) ES2083348T3 (da)
FI (1) FI112080B (da)
GR (2) GR960300021T1 (da)
HK (1) HK1012339A1 (da)
HU (1) HU216867B (da)
IL (1) IL114735A (da)
LU (1) LU91136I2 (da)
MA (1) MA23631A1 (da)
MY (1) MY114393A (da)
NL (1) NL300071I2 (da)
NO (2) NO312899B1 (da)
NZ (1) NZ272652A (da)
PE (1) PE32296A1 (da)
PL (1) PL180609B1 (da)
RU (1) RU2133749C1 (da)
SA (1) SA95160158B1 (da)
TR (1) TR199500895A2 (da)
TW (1) TW434242B (da)
UY (1) UY24006A1 (da)
ZA (1) ZA956228B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458772B1 (en) 1909-10-07 2002-10-01 Medivir Ab Prodrugs
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
WO1997027198A1 (en) * 1996-01-26 1997-07-31 F.Hoffmann-La Roche Ag Process for preparing purine derivatives
AU1592897A (en) * 1996-01-26 1997-08-20 F. Hoffmann-La Roche Ag Process for preparing purine derivatives
US5869493A (en) * 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
US6184376B1 (en) 1997-02-10 2001-02-06 Mediver Ab Synthesis of acyclic nucleoside derivatives
CA2277151C (en) * 1997-02-10 2007-04-17 Medivir Ab Synthesis of acyclic nucleoside derivatives
TR200000398T2 (tr) * 1997-08-15 2000-07-21 Medivir Ab Hepatit B virüsü (HBV) retroviral ters transkriptaz ve DNA polimeraz inhibe edicilerini içeren antiviraller gibi nükleozidlerin analogları.
AU1711599A (en) * 1997-12-19 1999-07-12 Bristol-Myers Squibb Company Prodrugs of lobucavir and methods of use
WO1999051613A1 (en) * 1998-04-03 1999-10-14 Medivir Ab Prodrugs of phosphorous-containing pharmaceuticals
KR20030015655A (ko) * 2001-08-17 2003-02-25 한미약품공업 주식회사 항암제의 경구흡수율을 증가시키는 인단계 화합물의결정성 산부가염, 이의 제조방법 및 이를 함유하는 약학적조성물
CA2483162C (en) * 2002-04-23 2011-08-23 Aventis Pharmaceuticals Inc. Use of 3-substituted amino-1h-indole-2-carboxylic acid and 3-substituted amino benzo[b]thiophene-2-carboxylic acid derivatives as il-4 inhibitors
EP2596792A1 (en) 2002-10-16 2013-05-29 Takeda Pharmaceutical Company Limited Stable solid preparations
US20040224917A1 (en) 2003-01-14 2004-11-11 Gilead Sciences, Inc. Compositions and methods for combination antiviral therapy
US20070129385A1 (en) * 2003-08-28 2007-06-07 Sharma Mukesh K Amorphous valganciclovir hydrochloride
EP1768668A2 (en) 2004-06-16 2007-04-04 Tap Pharmaceutical Products, Inc. Multiple ppi dosage form
CN101027318B (zh) * 2004-07-19 2016-05-25 比奥孔有限公司 胰岛素-低聚物共轭物，制剂及其用途
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
ZA200702234B (en) * 2006-03-21 2008-07-30 Cipla Ltd Preparation of ester of purine derivatives
KR20170097787A (ko) 2007-10-12 2017-08-28 다케다 파마슈티칼스 유에스에이, 인코포레이티드 음식 섭취와 관계없이 위장 장애를 치료하는 방법
CN103562207B (zh) * 2011-05-31 2016-08-17 法尔玛赞公司 用于制备缬更昔洛韦的2-氨基-9-((2-苯基-1，3-二噁烷-5-基氧基)甲基)-1h-嘌呤-6(9h)-酮化合物的制备方法
KR102312533B1 (ko) 2021-02-24 2021-10-15 주식회사 이웅 자동 스패너

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
IE842642L (en) * 1983-10-31 1985-04-30 Harvard College Purine Derivatives
NZ214520A (en) * 1984-12-12 1989-08-29 Syntex Inc Alkoxymethyl ether and ester derivatives in the production of guanine derivatives
AP160A (en) * 1987-08-15 1991-11-18 The Wellcome Foundation Ltd Therapeutic acyclic nucleosides.
EP0375329B1 (en) * 1988-12-19 1995-05-31 The Wellcome Foundation Limited Antiviral pyrimidine and purine compounds, process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE10299032I2 (de) 2006-06-14
CN1045089C (zh) 1999-09-15
FI953592A0 (fi) 1995-07-27
JPH0841061A (ja) 1996-02-13
KR960004345A (ko) 1996-02-23
GR960300021T1 (en) 1996-04-30
CY2180B1 (en) 2002-08-23
KR100358626B1 (ko) 2003-01-14
ZA956228B (en) 1996-02-22
MA23631A1 (fr) 1996-04-01
CN1122804A (zh) 1996-05-22
TW434242B (en) 2001-05-16
HUT73246A (en) 1996-07-29
CA2154721A1 (en) 1996-01-29
DE694547T1 (de) 1996-10-24
DE69509173D1 (de) 1999-05-27
RU95113148A (ru) 1997-06-27
EP0694547A3 (en) 1996-06-05
UY24006A1 (es) 2001-07-31
JP3090305B2 (ja) 2000-09-18
NZ272652A (en) 1996-12-20
BR9503468A (pt) 1996-02-27
ES2083348T3 (es) 1999-08-01
ATE179173T1 (de) 1999-05-15
EP0694547B1 (en) 1999-04-21
PE32296A1 (es) 1996-08-07
TR199500895A2 (tr) 1996-06-21
EP0694547A2 (en) 1996-01-31
CZ193995A3 (en) 1996-02-14
NL300071I2 (nl) 2002-03-01
AU2719595A (en) 1996-02-08
CY2004003I1 (el) 2009-11-04
CZ290511B6 (cs) 2002-08-14
SA95160158B1 (ar) 2006-05-20
CO4410181A1 (es) 1997-01-09
HK1012339A1 (en) 1999-07-30
LU91136I2 (fr) 2005-07-06
GR3030678T3 (en) 1999-11-30
NO952977D0 (no) 1995-07-27
IL114735A (en) 1998-06-15
NO952977L (no) 1996-01-29
RU2133749C1 (ru) 1999-07-27
MY114393A (en) 2002-10-31
FI953592A (fi) 1996-01-29
IL114735A0 (en) 1995-11-27
AU697107B2 (en) 1998-09-24
HU216867B (hu) 1999-09-28
DE10299032I1 (de) 2003-01-23
FI112080B (fi) 2003-10-31
ES2083348T1 (es) 1996-04-16
NO2003001I2 (no) 2007-06-11
PL309812A1 (en) 1996-02-05
PL180609B1 (pl) 2001-03-30
DE69509173T2 (de) 1999-10-21
HU9502238D0 (en) 1995-09-28
CA2154721C (en) 2001-01-02
NL300071I1 (nl) 2002-02-01
CY2004003I2 (el) 2009-11-04
NO312899B1 (no) 2002-07-15

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