CY2004003I1 - Παραγωγο 2-(2-αμινο-1,6-διυδρο-6-οξο-πυρινο-9-υλο)μεθοξυ-1,3-προπανεδιολης - Google Patents

Παραγωγο 2-(2-αμινο-1,6-διυδρο-6-οξο-πυρινο-9-υλο)μεθοξυ-1,3-προπανεδιολης

Info

Publication number
CY2004003I1
CY2004003I1 CY200400003C CY2004003C CY2004003I1 CY 2004003 I1 CY2004003 I1 CY 2004003I1 CY 200400003 C CY200400003 C CY 200400003C CY 2004003 C CY2004003 C CY 2004003C CY 2004003 I1 CY2004003 I1 CY 2004003I1
Authority
CY
Cyprus
Prior art keywords
pyrino
dihydro
oxo
methoxy
amino
Prior art date
Application number
CY200400003C
Other languages
English (en)
Other versions
CY2004003I2 (el
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23079211&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY2004003(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of CY2004003I1 publication Critical patent/CY2004003I1/el
Publication of CY2004003I2 publication Critical patent/CY2004003I2/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
CY200400003C 1994-07-28 2004-10-20 Παραγωγα 2-(2-αμινο-1, 6-διϋδρο-6-οξο-πυρινο-9-υλο)-μεθοδυ-1,3-προπανεδιολης CY2004003I2 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28189394A 1994-07-28 1994-07-28

Publications (2)

Publication Number Publication Date
CY2004003I1 true CY2004003I1 (el) 2009-11-04
CY2004003I2 CY2004003I2 (el) 2009-11-04

Family

ID=23079211

Family Applications (2)

Application Number Title Priority Date Filing Date
CY0000039A CY2180B1 (en) 1994-07-28 2000-08-10 2-(2Amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
CY200400003C CY2004003I2 (el) 1994-07-28 2004-10-20 Παραγωγα 2-(2-αμινο-1, 6-διϋδρο-6-οξο-πυρινο-9-υλο)-μεθοδυ-1,3-προπανεδιολης

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CY0000039A CY2180B1 (en) 1994-07-28 2000-08-10 2-(2Amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative

Country Status (33)

Country Link
EP (1) EP0694547B1 (el)
JP (1) JP3090305B2 (el)
KR (1) KR100358626B1 (el)
CN (1) CN1045089C (el)
AT (1) ATE179173T1 (el)
AU (1) AU697107B2 (el)
BR (1) BR9503468A (el)
CA (1) CA2154721C (el)
CO (1) CO4410181A1 (el)
CY (2) CY2180B1 (el)
CZ (1) CZ290511B6 (el)
DE (3) DE69509173T2 (el)
DK (1) DK0694547T3 (el)
ES (1) ES2083348T3 (el)
FI (1) FI112080B (el)
GR (2) GR960300021T1 (el)
HK (1) HK1012339A1 (el)
HU (1) HU216867B (el)
IL (1) IL114735A (el)
LU (1) LU91136I2 (el)
MA (1) MA23631A1 (el)
MY (1) MY114393A (el)
NL (1) NL300071I2 (el)
NO (2) NO312899B1 (el)
NZ (1) NZ272652A (el)
PE (1) PE32296A1 (el)
PL (1) PL180609B1 (el)
RU (1) RU2133749C1 (el)
SA (1) SA95160158B1 (el)
TR (1) TR199500895A2 (el)
TW (1) TW434242B (el)
UY (1) UY24006A1 (el)
ZA (1) ZA956228B (el)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458772B1 (en) 1909-10-07 2002-10-01 Medivir Ab Prodrugs
AU1592897A (en) * 1996-01-26 1997-08-20 F. Hoffmann-La Roche Ag Process for preparing purine derivatives
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
CN1064683C (zh) * 1996-01-26 2001-04-18 弗·哈夫曼-拉罗切有限公司 制备嘌呤衍生物的方法
US5869493A (en) * 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
US6184376B1 (en) 1997-02-10 2001-02-06 Mediver Ab Synthesis of acyclic nucleoside derivatives
CA2277151C (en) * 1997-02-10 2007-04-17 Medivir Ab Synthesis of acyclic nucleoside derivatives
SG96604A1 (en) * 1997-08-15 2003-06-16 Medivir Ab Nucleosides analogues, such as antivirals including inhibitors of retroviral reverse transcriptase and the dna polymerase of hepatitis b virus (hbv)
AU1711599A (en) * 1997-12-19 1999-07-12 Bristol-Myers Squibb Company Prodrugs of lobucavir and methods of use
WO1999051613A1 (en) * 1998-04-03 1999-10-14 Medivir Ab Prodrugs of phosphorous-containing pharmaceuticals
KR20030015655A (ko) * 2001-08-17 2003-02-25 한미약품공업 주식회사 항암제의 경구흡수율을 증가시키는 인단계 화합물의결정성 산부가염, 이의 제조방법 및 이를 함유하는 약학적조성물
ES2330628T3 (es) * 2002-04-23 2009-12-14 Aventis Pharmaceuticals Inc. Ester del acido 3-(amino sustituido)-1h-indol-2-carboxilico y derivados del ester del acido 3-(amino sustituido)-benzo(b)tiofeno-2-carboxilico como imhibidores de expresion del gen de interleucina-4.
US8697094B2 (en) 2002-10-16 2014-04-15 Takeda Pharmaceutical Company Limited Stable solid preparations
AU2004206827A1 (en) 2003-01-14 2004-08-05 Gilead Sciences, Inc. Compositions and methods for combination antiviral therapy
CA2537132A1 (en) * 2003-08-28 2005-03-10 Ranbaxy Laboratories Limited Amorphous valganciclovir hydrochloride
EP1768668A2 (en) 2004-06-16 2007-04-04 Tap Pharmaceutical Products, Inc. Multiple ppi dosage form
AU2005269753B2 (en) * 2004-07-19 2011-08-18 Biocon Limited Insulin-oligomer conjugates, formulations and uses thereof
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
ZA200702234B (en) * 2006-03-21 2008-07-30 Cipla Ltd Preparation of ester of purine derivatives
US8173158B2 (en) 2007-10-12 2012-05-08 Takeda Pharmaceuticals U.S.A., Inc. Methods of treating gastrointestinal disorders independent of the intake of food
CN103562207B (zh) * 2011-05-31 2016-08-17 法尔玛赞公司 用于制备缬更昔洛韦的2-氨基-9-((2-苯基-1，3-二噁烷-5-基氧基)甲基)-1h-嘌呤-6(9h)-酮化合物的制备方法
KR102312533B1 (ko) 2021-02-24 2021-10-15 주식회사 이웅 자동 스패너

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
IE842642L (en) * 1983-10-31 1985-04-30 Harvard College Purine Derivatives
KR910000198B1 (ko) * 1984-12-12 1991-01-23 신텍스(유.에스.에이.) 인코포레이티드 글리세롤의 알콕시메틸 에테르 및 알콕시메틸 에스테르의 제조방법
AP55A (en) * 1987-08-15 1989-09-26 The Wellcome Foundation Ltd Therapeutic Acyclic Nucleosides
CA2005815C (en) * 1988-12-19 1999-08-03 Wellcome Foundation Limited (The) Antiviral acyclic nucleoside derivatives

Also Published As

Publication number Publication date
AU2719595A (en) 1996-02-08
JP3090305B2 (ja) 2000-09-18
HK1012339A1 (en) 1999-07-30
NL300071I1 (nl) 2002-02-01
MY114393A (en) 2002-10-31
NO312899B1 (no) 2002-07-15
DE10299032I2 (de) 2006-06-14
JPH0841061A (ja) 1996-02-13
RU2133749C1 (ru) 1999-07-27
CA2154721A1 (en) 1996-01-29
NO2003001I2 (no) 2007-06-11
GR960300021T1 (en) 1996-04-30
NL300071I2 (nl) 2002-03-01
TW434242B (en) 2001-05-16
PL180609B1 (pl) 2001-03-30
TR199500895A2 (tr) 1996-06-21
PE32296A1 (es) 1996-08-07
CZ193995A3 (en) 1996-02-14
CO4410181A1 (es) 1997-01-09
CY2004003I2 (el) 2009-11-04
ES2083348T3 (es) 1999-08-01
FI953592A (fi) 1996-01-29
ZA956228B (en) 1996-02-22
BR9503468A (pt) 1996-02-27
NO952977D0 (no) 1995-07-27
DE694547T1 (de) 1996-10-24
DE69509173D1 (de) 1999-05-27
PL309812A1 (en) 1996-02-05
IL114735A0 (en) 1995-11-27
FI112080B (fi) 2003-10-31
EP0694547B1 (en) 1999-04-21
AU697107B2 (en) 1998-09-24
EP0694547A3 (en) 1996-06-05
LU91136I2 (fr) 2005-07-06
NZ272652A (en) 1996-12-20
MA23631A1 (fr) 1996-04-01
CZ290511B6 (cs) 2002-08-14
EP0694547A2 (en) 1996-01-31
ES2083348T1 (es) 1996-04-16
GR3030678T3 (en) 1999-11-30
IL114735A (en) 1998-06-15
HU9502238D0 (en) 1995-09-28
NO952977L (no) 1996-01-29
RU95113148A (ru) 1997-06-27
CA2154721C (en) 2001-01-02
HU216867B (hu) 1999-09-28
KR100358626B1 (ko) 2003-01-14
ATE179173T1 (de) 1999-05-15
CN1122804A (zh) 1996-05-22
DE69509173T2 (de) 1999-10-21
CY2180B1 (en) 2002-08-23
DE10299032I1 (de) 2003-01-23
SA95160158B1 (ar) 2006-05-20
HUT73246A (en) 1996-07-29
DK0694547T3 (da) 2000-01-03
KR960004345A (ko) 1996-02-23
UY24006A1 (es) 2001-07-31
FI953592A0 (fi) 1995-07-27
CN1045089C (zh) 1999-09-15

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