CY1122713T1 - Στοματικα χορηγουμενες συνθεσεις κορτικοστεροειδων - Google Patents

Στοματικα χορηγουμενες συνθεσεις κορτικοστεροειδων

Info

Publication number
CY1122713T1
CY1122713T1 CY20191100883T CY191100883T CY1122713T1 CY 1122713 T1 CY1122713 T1 CY 1122713T1 CY 20191100883 T CY20191100883 T CY 20191100883T CY 191100883 T CY191100883 T CY 191100883T CY 1122713 T1 CY1122713 T1 CY 1122713T1
Authority
CY
Cyprus
Prior art keywords
orally administered
corticosteroid compositions
administered corticosteroid
present
subject
Prior art date
Application number
CY20191100883T
Other languages
English (en)
Inventor
Stephen Perrett
Fredric Jay Cohen
Gopi M. Venkatesh
Original Assignee
Adare Development I, L.P.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43823361&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1122713(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Adare Development I, L.P. filed Critical Adare Development I, L.P.
Publication of CY1122713T1 publication Critical patent/CY1122713T1/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Steroid Compounds (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε στοματικά χορηγούμενες συνθέσεις κορτικοστεροειδών. Η παρούσα εφεύρεση παρέχει επίσης μια μέθοδο για τη θεραπεία μιας πάθησης που σχετίζεται με τη φλεγμονή της γαστρεντερικής οδού σε ένα άτομο. Η μέθοδος περιλαμβάνει τη χορήγηση σε ένα άτομο που έχει ανάγκη αυτής μιας φαρμακευτικής σύνθεσης της παρούσας εφεύρεσης.
CY20191100883T 2009-10-01 2019-08-19 Στοματικα χορηγουμενες συνθεσεις κορτικοστεροειδων CY1122713T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24764209P 2009-10-01 2009-10-01
EP10821232.5A EP2482822B1 (en) 2009-10-01 2010-09-30 Orally administered corticosteroid compositions
PCT/US2010/050860 WO2011041509A1 (en) 2009-10-01 2010-09-30 Orally administered corticosteroid compositions

Publications (1)

Publication Number Publication Date
CY1122713T1 true CY1122713T1 (el) 2021-03-12

Family

ID=43823361

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20191100883T CY1122713T1 (el) 2009-10-01 2019-08-19 Στοματικα χορηγουμενες συνθεσεις κορτικοστεροειδων

Country Status (35)

Country Link
US (8) US8771729B2 (el)
EP (4) EP3760187A1 (el)
JP (7) JP2013506683A (el)
KR (3) KR20140088236A (el)
CN (3) CN102665722A (el)
AR (1) AR078499A1 (el)
AU (1) AU2010300550B2 (el)
BR (2) BR122022005637B1 (el)
CA (3) CA2776164C (el)
CL (1) CL2012000794A1 (el)
CO (1) CO6531427A2 (el)
CY (1) CY1122713T1 (el)
DE (1) DE202010018594U1 (el)
DK (2) DK3403654T3 (el)
EA (2) EA031157B9 (el)
ES (2) ES2683864T3 (el)
GE (1) GEP20156281B (el)
HR (2) HRP20181266T1 (el)
HU (2) HUE040119T2 (el)
IL (2) IL218928A (el)
LT (2) LT3403654T (el)
ME (1) ME03471B (el)
MX (4) MX364947B (el)
MY (1) MY171317A (el)
NZ (2) NZ599401A (el)
PL (2) PL3403654T3 (el)
PT (2) PT3403654T (el)
RS (2) RS57595B1 (el)
SG (3) SG10201704847WA (el)
SI (2) SI3403654T1 (el)
TW (2) TWI594754B (el)
UA (2) UA108360C2 (el)
UY (1) UY32925A (el)
WO (1) WO2011041509A1 (el)
ZA (2) ZA201202208B (el)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
EP3574914B1 (en) 2007-11-13 2021-12-29 ViroPharma Biologics LLC Corticosteroid compositions
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US8865692B2 (en) 2007-11-13 2014-10-21 Meritage Pharma, Inc Compositions for the treatment of gastrointestinal inflammation
EP2440210A4 (en) * 2009-06-12 2014-01-29 Meritage Pharma Inc METHOD FOR THE TREATMENT OF STOMACH DARM DISEASES
ES2683864T3 (es) 2009-10-01 2018-09-28 Adare Pharmaceuticals, Inc. Composiciones de corticosteroides administradas oralmente
EP2585075B8 (en) * 2010-06-24 2021-09-22 ViroPharma Biologics LLC Methods of treatment for esophageal inflammation
WO2012020279A1 (en) * 2010-08-13 2012-02-16 Compagnie Gervais Danone Product for the upper gastric sphere
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
MX361886B (es) 2012-05-08 2018-12-18 Nicox Ophthalmics Inc Preparaciones de agentes terapéuticos hidrófobos, métodos de elaboración y uso de los mismos.
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
US10716802B2 (en) 2013-03-15 2020-07-21 The Brigham And Women's Hospital, Inc. Compounds to modulate intestinal absorption of nutrients
CA2906029C (en) * 2013-03-15 2017-09-05 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
GB201308933D0 (en) * 2013-05-17 2013-07-03 Diurnal Ltd Paediatric composition
US9078853B2 (en) * 2013-06-18 2015-07-14 Cmpd Licensing, Llc Dry pharmaceutical compositions for topical delivery of oral medications, nasal delivery and to treat ear disorders
WO2015034678A2 (en) * 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
WO2015152517A1 (ko) * 2014-03-31 2015-10-08 (주)세하바이오 항산화 물질 활성 보호를 위한 프롤라민 기반 경구용 필름 제조방법
US9980975B2 (en) 2015-01-22 2018-05-29 Ems S.A. Dosage forms containing fluticasone propionate for the treatment of inflammatory conditions of the esophagus
EP3047846A1 (en) 2015-01-22 2016-07-27 Ems S.A. Dosage forms containing fluticasone propionate for the treatment of inflammatory conditions of the esophagus
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US9867834B2 (en) 2015-06-15 2018-01-16 Banner Life Sciences Llc Non-systemic topical compositions comprising corticosteroids
WO2016205172A1 (en) 2015-06-15 2016-12-22 Banner Life Sciences Llc Soft lozenges comprising corticosteroids
US10973846B2 (en) 2015-09-24 2021-04-13 The Brigham And Women's Hospital, Inc. Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients
CN105412123B (zh) * 2015-11-06 2018-03-13 山东省千佛山医院 布地奈德联合三唑类抗真菌药物的应用及其产品
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
TWI728172B (zh) 2016-08-18 2021-05-21 美商愛戴爾製藥股份有限公司 治療嗜伊紅性食道炎之方法
US9999604B2 (en) 2016-11-17 2018-06-19 Cmpd Licensing, Llc Compounded solutions of diclofenac and lidocaine and methods
US10966946B2 (en) 2016-11-17 2021-04-06 Cmpd Licensing, Llc Compounded compositions and methods for treating pain
US11737975B2 (en) 2016-11-17 2023-08-29 Cmpd Licensing, Llc Compounded compositions and methods for treating pain
US11986448B2 (en) 2016-11-17 2024-05-21 Cmpd Licensing, Llc Compounded compositions and methods for treating pain
US10525025B2 (en) 2016-11-17 2020-01-07 Cmpd Licensing, Llc Compounded compositions and methods for treating pain
CN107595765A (zh) * 2017-09-22 2018-01-19 沈阳兴齐眼药股份有限公司 一种眼用缓释药物递送系统及其制备方法
WO2019157453A1 (en) * 2018-02-12 2019-08-15 Trilogy Therapeutics, Inc. Caspofungin compositions for inhalation
SI25373A (sl) 2018-05-08 2018-08-31 Danijela Marković Naravna orodisperzibilna tableta
WO2020227437A1 (en) 2019-05-06 2020-11-12 Axial Biotherapeutics, Inc. Sustained release solid dosage forms for modulating the colonic microbiome
KR20220074915A (ko) * 2019-10-01 2022-06-03 엘로디 파마슈티컬스, 엘.피. 호산구성 식도염을 치료하고 칸디다증을 감소시키는 방법
KR102275997B1 (ko) * 2019-11-07 2021-07-13 연세대학교 산학협력단 숙주지향치료를 위한 조성물
CN114146089B (zh) * 2021-12-15 2023-06-16 安徽贝克生物制药有限公司 含依非韦伦、替诺福韦和恩曲他滨的药物组合物
CN116869927B (zh) * 2023-09-06 2023-11-10 中国医学科学院北京协和医院 一种用于治疗嗜酸性食管炎的食道温敏凝胶

Family Cites Families (96)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1170188A (en) 1967-09-15 1969-11-12 Bayer Ag N-trityl-imidazoles and salts and uses thereof
SE378109B (el) 1972-05-19 1975-08-18 Bofors Ab
DE2260384C3 (de) * 1972-12-09 1979-11-29 Hoechst Ag, 6000 Frankfurt Oral zu applizierendes Corticosteroid-Präparat
US4080448A (en) 1974-11-13 1978-03-21 Mirsky Louis H Method of treating cellular stress
JPS56138200A (en) * 1980-02-15 1981-10-28 Glaxo Group Ltd Androstane carbothioate compound
SE8004580L (sv) 1980-06-19 1981-12-20 Draco Ab Farmaceutisk beredning
ATE8790T1 (de) 1981-02-02 1984-08-15 Schering Corporation Aromatische heterocyclische steroidester, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen, die sie enthalten.
GB8630913D0 (en) 1986-12-24 1987-02-04 Glaxo Group Ltd Pharmaceutical compositions
US5446070A (en) 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
ZA892859B (en) 1988-04-22 1989-12-27 Advanced Polymer Systems Inc Porous particles in preparations involving immiscible phases
GB9002375D0 (en) 1990-02-02 1990-04-04 Pfizer Ltd Triazole antifungal agents
US5278175A (en) 1990-02-02 1994-01-11 Pfizer Inc. Triazole antifungal agents
GR1001529B (el) 1990-09-07 1994-03-31 Elmuquimica Farm Sl Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
CA2101773A1 (en) 1991-01-31 1992-08-01 Toyoichi Tanaka Interpenetrating-polymer network phase-transition gels
US5252337A (en) 1991-06-25 1993-10-12 Eurand America, Inc. Controlled release calcium channel blocker microcapsules
DK0735884T3 (da) 1993-12-20 2000-10-09 Minnesota Mining & Mfg Flunisolid-aerosolformuleringer
US5639475A (en) 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules
SE9501384D0 (sv) * 1995-04-13 1995-04-13 Astra Ab Process for the preparation of respirable particles
GB9517062D0 (en) 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
DE19606151C2 (de) 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
EP1598061B1 (en) 1996-06-14 2010-08-18 Kyowa Hakko Kirin Co., Ltd. Intraorally rapidly disintegrable tablet
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
NZ334914A (en) 1996-10-01 2000-09-29 Stanford Res Inst Int Taste-masked microcapsule compositions and methods of manufacture using a phase seperation-coacervation technique
SE9604486D0 (sv) 1996-12-05 1996-12-05 Astra Ab Novel formulation
GB9707934D0 (en) 1997-04-18 1997-06-04 Danbiosyst Uk Improved delivery of drugs to mucosal surfaces
IT1291362B1 (it) 1997-05-13 1999-01-07 Vectorpharma Int Composizioni farmaceutiche multicomponente bifasiche contenenti sostanze atte a modificare la partizione dei principi attivi
RO118174B1 (ro) 1997-08-21 2003-03-28 Aventis Pharma Deutschland Gmbh Lac de unghii şi utilizarea acestuia
GB9722426D0 (en) 1997-10-23 1997-12-24 Univ London Pharmacy Controlled release formulations
AU741992B2 (en) 1998-03-06 2001-12-13 Adare Pharmaceuticals S.R.L. Fast disintegrating tablets
FR2781156B1 (fr) 1998-07-20 2001-06-29 Lafon Labor Composition pharmaceutique destinee notamment a la prevention et au traitement des radiomucites et des chimiomucites
US6596298B2 (en) 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US6863378B2 (en) 1998-10-16 2005-03-08 Silverbrook Research Pty Ltd Inkjet printer having enclosed actuators
ES2671785T3 (es) 1999-04-23 2018-06-08 Leo Pharma A/S Composición farmacéutica para uso dérmico para el tratamiento de la psoriasis que comprende vitamina D y un corticosteroide
GB9915319D0 (en) 1999-06-30 1999-09-01 Unilever Plc Hair treatment compositions
DE60031504T2 (de) 1999-09-11 2007-04-05 Glaxo Group Ltd., Greenford Fluticasonpropionat arzneizubereitung
KR100446101B1 (ko) * 2000-12-07 2004-08-30 주식회사 삼양사 수난용성 약물의 서방성 제형 조성물
EP1367999A4 (en) 2001-02-16 2007-04-18 Lavipharm Lab Inc WATER-SOLUBLE AND PALATABLE COMPLEXES
US20030050312A1 (en) 2001-03-12 2003-03-13 Hjorth Thyge Borup Novel tablets and capsules and a process for its preparation
CA2440935A1 (en) * 2001-03-13 2002-09-19 Richard Liggins Micellar drug delivery vehicles and precursors thereto and uses thereof
US6872405B2 (en) * 2001-05-10 2005-03-29 Yamanouchi Pharmaceutical Co., Ltd. Quick-disintegrating tablet in buccal cavity and manufacturing method thereof
ATE333269T1 (de) * 2001-05-10 2006-08-15 Astellas Pharma Inc In der mundhöhle schnell zerfallende tabletten und prozess zu deren herstellung
US6656493B2 (en) 2001-07-30 2003-12-02 Wm. Wrigley Jr. Company Edible film formulations containing maltodextrin
FR2831820B1 (fr) 2001-11-05 2004-08-20 Ethypharm Sa Comprime orodispersible presentant une grande homogeneite et son procede de preparation
US20030206978A1 (en) 2001-11-29 2003-11-06 Bob Sherwood Agglomerated particles including an active agent coprocessed with silicified microcrystalline cellulose
US20040009212A1 (en) 2002-01-30 2004-01-15 Pharma Power Biotec Co. Ltd. Mucoadhesive thermoresponsive medicament-carrier composition
JP4173670B2 (ja) * 2002-03-08 2008-10-29 旭化成ファーマ株式会社 口腔内崩壊製剤
US6958192B2 (en) 2002-04-05 2005-10-25 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Polyimides from 2,3,3′,4′-biphenyltetracarboxylic dianhydride and aromatic diamines
EP1504047B1 (en) * 2002-05-03 2007-12-12 Janssen Pharmaceutica N.V. Polymeric microemulsions
EP1530842A4 (en) 2002-07-10 2008-03-19 I O Controls Corp OPTICAL FIBER CONTROL NETWORK AND ASSOCIATED METHOD
WO2004021997A2 (en) * 2002-09-06 2004-03-18 Microbia, Inc. Inhibitors of fungal invasion
WO2004023984A2 (en) 2002-09-13 2004-03-25 Smith C Steven Novel composition and method for treatment of upper respiratory conditions
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
EP1595533B1 (en) * 2003-01-21 2010-01-06 Nippon Shinyaku Co., Ltd. Tablet quickly melting in oral cavity
US20060216352A1 (en) 2003-01-31 2006-09-28 Orexo Ab Rapid-acting pharmaceutical composition
US20040208833A1 (en) * 2003-02-04 2004-10-21 Elan Pharma International Ltd. Novel fluticasone formulations
US8012505B2 (en) 2003-02-28 2011-09-06 Alk-Abello A/S Dosage form having a saccharide matrix
US20040265375A1 (en) 2003-04-16 2004-12-30 Platteeuw Johannes J. Orally disintegrating tablets
US20050009848A1 (en) * 2003-07-10 2005-01-13 Icn Pharmaceuticals Switzerland Ltd. Use of antivirals against inflammatory bowel diseases
JP2007528388A (ja) 2004-03-10 2007-10-11 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト 分子分散されたドロスピレノンを含む組成物
US8545881B2 (en) * 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
DE602004004782T2 (de) 2004-09-09 2007-10-31 Laboratorio Medinfar-Produtos Farmacéuticos, S. A. Schnell wasserdispergierbare und Domperidon enthaltende Tabletten
US20060105038A1 (en) 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US20060292099A1 (en) 2005-05-25 2006-12-28 Michael Milburn Treatment of eye disorders with sirtuin modulators
US20070059361A1 (en) * 2005-09-09 2007-03-15 University Of Manitoba Fast-disintegrating epinephrine tablets for buccal or sublingual administration
US8679545B2 (en) 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8497258B2 (en) * 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
CN1985799B (zh) * 2005-12-19 2011-11-09 量子高科(北京)研究院有限公司 口腔崩解制剂的制备方法
BRPI0620578A2 (pt) 2005-12-27 2011-12-06 Jubilant Organosys Ltd composição farmacêutica que dissolve na boca e processo para o preparo da mesma
US20080260655A1 (en) * 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
EP1958613A1 (en) 2007-02-15 2008-08-20 Polichem S.A. Dermal film-forming liquid formulations for drug release to skin
EP2148659A2 (en) 2007-04-13 2010-02-03 Somaxon Pharmaceuticals, Inc. Low-dose doxepin formulations
US8865692B2 (en) * 2007-11-13 2014-10-21 Meritage Pharma, Inc Compositions for the treatment of gastrointestinal inflammation
US20090123551A1 (en) * 2007-11-13 2009-05-14 Meritage Pharma, Inc. Gastrointestinal delivery systems
EP3574914B1 (en) 2007-11-13 2021-12-29 ViroPharma Biologics LLC Corticosteroid compositions
US20150231156A1 (en) 2007-11-13 2015-08-20 Meritage Pharma, Inc. Corticosteroid compositions
US20100216754A1 (en) 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
WO2009076361A1 (en) * 2007-12-10 2009-06-18 Eurand, Inc. Orally disintegrating tablets comprising diphenhydramine
KR20100103844A (ko) * 2007-12-21 2010-09-28 유란드, 인코포레이티드 테마제팜의 경구 붕해 타블릿 조성물
JP2009173552A (ja) * 2008-01-21 2009-08-06 Lion Corp 胃腸薬
SE533435C2 (sv) 2008-04-03 2010-09-28 Hm Power Ab Vridmomentsöverförande arrangemang vid ett vindkraftverk
DK2151235T3 (da) 2008-07-21 2011-04-11 Falk Pharma Gmbh Farmaceutisk formulering til behandling af den øvre fordøjelseskanal
CN102112114A (zh) 2008-08-08 2011-06-29 麦克内尔-Ppc股份有限公司 使用三氯蔗糖作为制粒剂
WO2010021636A1 (en) 2008-08-20 2010-02-25 The Regents Of The University Of California Corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
EP2440210A4 (en) * 2009-06-12 2014-01-29 Meritage Pharma Inc METHOD FOR THE TREATMENT OF STOMACH DARM DISEASES
ES2683864T3 (es) 2009-10-01 2018-09-28 Adare Pharmaceuticals, Inc. Composiciones de corticosteroides administradas oralmente
WO2012075455A2 (en) 2010-12-02 2012-06-07 Aptalis Pharmatech, Inc. Rapidly dispersing granules, orally disintegrating tablets and methods
WO2015034678A2 (en) 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
PT2886108T (pt) 2013-12-23 2019-04-01 Dr Falk Pharma Gmbh Formulação farmacêutica otimizada para o tratamento de alterações inflamatórias do esófago
WO2015142739A1 (en) 2014-03-17 2015-09-24 Children's Hospital Medical Center Genetic test for determining susceptibility for eosinophilic esophagitis
US10176301B2 (en) 2014-09-11 2019-01-08 Meritage Pharma, Inc. Systems, methods, and software for providing a patient-reported outcome measure of dysphagia patients with eosinophilic esophagitis
US9980975B2 (en) 2015-01-22 2018-05-29 Ems S.A. Dosage forms containing fluticasone propionate for the treatment of inflammatory conditions of the esophagus
TWI728172B (zh) 2016-08-18 2021-05-21 美商愛戴爾製藥股份有限公司 治療嗜伊紅性食道炎之方法
RU2020128551A (ru) 2018-02-21 2022-03-21 АДЭР ФАРМАСЬЮТИКАЛЗ ЮЭс, Л.П. Способы ведения эозинофильного эзофагита
KR20220074915A (ko) 2019-10-01 2022-06-03 엘로디 파마슈티컬스, 엘.피. 호산구성 식도염을 치료하고 칸디다증을 감소시키는 방법

Also Published As

Publication number Publication date
IL238915A (en) 2017-06-29
IL218928A0 (en) 2012-07-31
JP2022078275A (ja) 2022-05-24
IL238915A0 (en) 2015-06-30
SI3403654T1 (sl) 2019-10-30
HUE040119T2 (hu) 2019-02-28
SG10201704847WA (en) 2017-07-28
GEP20156281B (en) 2015-05-11
US20210244660A1 (en) 2021-08-12
EA031157B9 (ru) 2019-01-31
UA108360C2 (uk) 2015-04-27
JP7042015B2 (ja) 2022-03-25
US20200214979A1 (en) 2020-07-09
LT2482822T (lt) 2018-09-10
CA3037273A1 (en) 2011-04-07
US20140303131A1 (en) 2014-10-09
CN102665722A (zh) 2012-09-12
AU2010300550B2 (en) 2014-10-30
CA3037273C (en) 2022-05-03
CA2940931C (en) 2019-04-30
NZ624922A (en) 2016-05-27
RS59241B1 (sr) 2019-10-31
PT3403654T (pt) 2019-09-05
ZA201202208B (en) 2014-11-26
ME03471B (me) 2020-01-20
US8771729B2 (en) 2014-07-08
MX2012003823A (es) 2012-07-30
KR20140088236A (ko) 2014-07-09
TWI562779B (en) 2016-12-21
US20110081411A1 (en) 2011-04-07
JP2023166486A (ja) 2023-11-21
HUE046748T2 (hu) 2020-03-30
AU2010300550A1 (en) 2012-04-12
CN106421797A (zh) 2017-02-22
UA118087C2 (uk) 2018-11-26
SG10201912526TA (en) 2020-02-27
NZ599401A (en) 2014-09-26
JP2017036306A (ja) 2017-02-16
CN107252488A (zh) 2017-10-17
HRP20181266T1 (hr) 2018-10-05
EA201290171A1 (ru) 2012-11-30
SI2482822T1 (sl) 2018-10-30
EP2482822B1 (en) 2018-08-01
KR20150043548A (ko) 2015-04-22
SG10201405886WA (en) 2014-11-27
EP2482822A4 (en) 2014-03-12
US9486407B2 (en) 2016-11-08
US11246828B2 (en) 2022-02-15
TW201521732A (zh) 2015-06-16
MX2022003132A (es) 2022-05-16
CO6531427A2 (es) 2012-09-28
DK3403654T3 (da) 2019-08-26
DE202010018594U1 (de) 2018-02-16
PL3403654T3 (pl) 2019-11-29
JP2013506683A (ja) 2013-02-28
US10632069B2 (en) 2020-04-28
RS57595B1 (sr) 2018-11-30
LT3403654T (lt) 2019-09-10
EA031157B1 (ru) 2018-11-30
US11266598B2 (en) 2022-03-08
KR20120104975A (ko) 2012-09-24
JP6293230B2 (ja) 2018-03-14
DK2482822T3 (en) 2018-08-27
EP3403654B1 (en) 2019-07-31
EA201491358A1 (ru) 2015-03-31
TW201117815A (en) 2011-06-01
ES2683864T3 (es) 2018-09-28
JP2020097625A (ja) 2020-06-25
PT2482822T (pt) 2018-10-04
UY32925A (es) 2011-04-29
EP3403654A1 (en) 2018-11-21
AR078499A1 (es) 2011-11-09
HRP20191435T1 (hr) 2019-11-15
US20170071855A1 (en) 2017-03-16
US9387167B2 (en) 2016-07-12
WO2011041509A1 (en) 2011-04-07
ES2742525T3 (es) 2020-02-14
ZA201301380B (en) 2014-07-30
US20180153802A1 (en) 2018-06-07
US9849084B2 (en) 2017-12-26
JP2015096540A (ja) 2015-05-21
EA024084B1 (ru) 2016-08-31
JP6249935B2 (ja) 2017-12-20
US20220339098A1 (en) 2022-10-27
EP3760187A1 (en) 2021-01-06
IL218928A (en) 2016-10-31
PL2482822T3 (pl) 2018-10-31
CA2940931A1 (en) 2011-04-07
MX2019005289A (es) 2019-08-05
CL2012000794A1 (es) 2012-07-20
MY171317A (en) 2019-10-08
US20140287051A1 (en) 2014-09-25
EP2482822A1 (en) 2012-08-08
BR122022005637B1 (pt) 2023-03-07
CA2776164A1 (en) 2011-04-07
MX364947B (es) 2019-05-15
CA2776164C (en) 2016-12-13
EP2845595A1 (en) 2015-03-11
TWI594754B (zh) 2017-08-11
JP2018100286A (ja) 2018-06-28
MX2020007226A (es) 2020-10-12
BR112012007110A2 (pt) 2021-08-31

Similar Documents

Publication Publication Date Title
CY1122713T1 (el) Στοματικα χορηγουμενες συνθεσεις κορτικοστεροειδων
CY1123126T1 (el) Συνθεσεις για την αγωγη γαστρεντερικης φλεγμονης
CY1118661T1 (el) Φαρμακευτικη συνθεση, φαρμακευτικη δοσολογικη μορφη, διαδικασια για την παρασκευη τους, μεθοδοι για αντιμετωπιση και χρησεις αυτων
CY1120807T1 (el) Συνθεσεις και μεθοδοι για την τροποποιηση της smn2 συναρμογης σε ενα υποκειμενο
CY1124307T1 (el) Φαρμακευτικη συνθεση, μεθοδοι θεραπειας και χρησεις αυτων
CY1120939T1 (el) Συνδυασμος ρεγοραφενιμπης και ακετυλοσαλικυλικου οξεος για τη θεραπευτικη αντιμετωπιση του ορθοκολικου καρκινου
CY1120429T1 (el) Παραγωγα κιναζολινης για τη θεραπευτικη αντιμετωπιση ιογενων λοιμωξεων και αλλων νοσων
CY1122626T1 (el) Κορτικοστεροειδες που περιεχει τις συνθεσεις των δισκιων που διασπωνται απο το στομα για την ηωσινοφιλικη οισοφαγιτιδα
CY1117118T1 (el) Φαρμακευτικος συνδυασμος για την αγωγη του πονου
CY1123279T1 (el) Κορτικοστεροειλη για τη θεραπεια φλεγμονωδων παθησεων της γαστρεντερικης οδου
CY1114988T1 (el) Βενζοδιαζεπινη αναστολεας bromodomain
CY1118099T1 (el) Δισκια οξεικης ουλιπρισταλης
CY1122809T1 (el) Εστερικα προ-φαρμακα της [3-(1-(1η-ιμιδαζολ-4-υλ)αιθυλο)-2-μεθυλοφαινυλο) μεθανολης για τη θεραπεια οφθαλμικων νοσηματων
EA201390804A1 (ru) Лекарственная форма лакозамида для приема один раз в сутки
EA201391087A1 (ru) Оральные лекарственные формы препарата тазоцитиниба с модифицированным высвобождением
CY1115381T1 (el) Διενυδρη υδροχλωρικη ναλμεφαινη
CY1120852T1 (el) Φαρμακευτικη συνθεση η οποια περιλαμβανει ιβουπροφαινη, τραμαδολη και ενα βασικο αμινοξυ, μεθοδος παρασκευης αυτης και χρηση της ιδιας
CY1114960T1 (el) Συνθεσεις που περιλαμβανουν τραμαδολη και σελεκοξιμπη στην θεραπεια πονου
CY1119413T1 (el) Μεθοδος για την παραγωγη και τη χρηση ενος συμπολυμερους νατριουχου καρβοξυμεθυλοκυτταρινης και γκοσυπολης
TR200903036A2 (tr) Tiyokolşikozit ve non-steroidal anti-enflamatuar ilaç kombinasyonları
EA201591150A1 (ru) Твердая единая форма с высоким содержанием фексофенадина и способ ее получения
CY1120545T1 (el) Συνθεση για τη θεραπεια της διαταραχης μειωμενης σεξουαλικης επιθυμιας
MX343409B (es) Combinaciones farmaceuticas que incluyen conjugados antiinflamatorios y antioxidantes utiles para tratar trastornos metabolicos.
CY1121280T1 (el) Χρηση της θυαζολοπυριμιδινονης για τη θεραπεια της φλεγμονωδους νοσου του εντερου
CY1120931T1 (el) Συνθεσεις διπροπιονικης βεκλομεθαζονης σε τροποποιημενης-απελευθερωσης γαστρο-ανθεκτικες μικροσφαιρες