CY1120931T1 - Συνθεσεις διπροπιονικης βεκλομεθαζονης σε τροποποιημενης-απελευθερωσης γαστρο-ανθεκτικες μικροσφαιρες - Google Patents

Συνθεσεις διπροπιονικης βεκλομεθαζονης σε τροποποιημενης-απελευθερωσης γαστρο-ανθεκτικες μικροσφαιρες

Info

Publication number
CY1120931T1
CY1120931T1 CY181101257T CY181101257T CY1120931T1 CY 1120931 T1 CY1120931 T1 CY 1120931T1 CY 181101257 T CY181101257 T CY 181101257T CY 181101257 T CY181101257 T CY 181101257T CY 1120931 T1 CY1120931 T1 CY 1120931T1
Authority
CY
Cyprus
Prior art keywords
modified
gastro
resistant
beclomethasone
compositions
Prior art date
Application number
CY181101257T
Other languages
English (en)
Inventor
Carla Labruzzo
Original Assignee
Sofar Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sofar Spa filed Critical Sofar Spa
Publication of CY1120931T1 publication Critical patent/CY1120931T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Η παρούσα εφεύρεση αναφέρεται σε φαρμακευτικές συνθέσεις διπροπιονικής βεκλομεθαζόνης σε τροποποιημένης-απελευθέρωσης γαστρο-ανθεκτικές μικροσφαίρες και στην στοματική τους χρήση στην αντιμετώπιση φλεγμονωδών παθολογιών της εντερικής οδού.
CY181101257T 2010-08-06 2018-11-27 Συνθεσεις διπροπιονικης βεκλομεθαζονης σε τροποποιημενης-απελευθερωσης γαστρο-ανθεκτικες μικροσφαιρες CY1120931T1 (el)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI2010A001512A IT1405012B1 (it) 2010-08-06 2010-08-06 Composizioni di beclometasone dipropionato in microsfere gastroresistenti a rilascio modificato e processo per il loro ottenimento
EP11754741.4A EP2600852A2 (en) 2010-08-06 2011-08-02 Beclomethasone dipropionate compositions in modified-release gastro-resistant microspheres and process for obtaining them
PCT/IB2011/053430 WO2012017385A2 (en) 2010-08-06 2011-08-02 Beclomethasone dipropionate compositions in modified-release gastro-resistant microspheres and process for obtaining them

Publications (1)

Publication Number Publication Date
CY1120931T1 true CY1120931T1 (el) 2019-12-11

Family

ID=43707817

Family Applications (1)

Application Number Title Priority Date Filing Date
CY181101257T CY1120931T1 (el) 2010-08-06 2018-11-27 Συνθεσεις διπροπιονικης βεκλομεθαζονης σε τροποποιημενης-απελευθερωσης γαστρο-ανθεκτικες μικροσφαιρες

Country Status (10)

Country Link
US (1) US10028917B2 (el)
EP (2) EP3009130B1 (el)
CA (1) CA2806519C (el)
CY (1) CY1120931T1 (el)
DK (1) DK3009130T3 (el)
ES (1) ES2701264T3 (el)
HK (1) HK1223570A1 (el)
IT (1) IT1405012B1 (el)
PT (1) PT3009130T (el)
WO (1) WO2012017385A2 (el)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201202433D0 (en) * 2012-02-13 2012-03-28 Diurnal Ltd Controlled drug release

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57500432A (el) 1980-03-20 1982-03-11
IL92343A0 (en) * 1988-12-20 1990-07-26 Gist Brocades Nv Granulate for multiparticulate controlled release oral compositions,their preparation and oral pharmaceutical compositions containing them
JP3469926B2 (ja) * 1993-11-04 2003-11-25 太田製薬株式会社 大腸内放出型医薬製剤用粒状物
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
EP0876142B1 (en) * 1996-01-16 2001-09-26 Advanced Polymer Systems, Inc. Topical delivery of drugs to the lower gastrointestinal tract
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
ATE477804T1 (de) * 2001-03-15 2010-09-15 Soligenix Inc Verfahren zur behandlung von entzündlichen erkrankungen des verdauungstrakts mit topisch wirksamen kortikosteroiden
US8238554B2 (en) 2004-07-22 2012-08-07 Sanyo Electric Co., Ltd. Method for transmission/reception of contents usage right information in encrypted form, and device thereof
US9149439B2 (en) 2005-03-21 2015-10-06 Sandoz Ag Multi-particulate, modified-release composition
US20080081070A1 (en) * 2006-09-15 2008-04-03 Auriga Laboratories, Inc. Pharmaceutical formulation with enhanced solubility for the delivery of corticosteroids

Also Published As

Publication number Publication date
EP3009130A1 (en) 2016-04-20
US10028917B2 (en) 2018-07-24
DK3009130T3 (en) 2018-12-17
IT1405012B1 (it) 2013-12-16
WO2012017385A2 (en) 2012-02-09
CA2806519A1 (en) 2012-02-09
PT3009130T (pt) 2018-12-14
EP3009130B1 (en) 2018-10-10
WO2012017385A3 (en) 2012-04-19
ITMI20101512A1 (it) 2012-02-07
ES2701264T3 (es) 2019-02-21
CA2806519C (en) 2019-03-26
EP2600852A2 (en) 2013-06-12
US20130142880A1 (en) 2013-06-06
HK1223570A1 (zh) 2017-08-04

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