CY1117559T1 - Ενωση ινδολιου και φαρμακευτικη χρηση αυτου - Google Patents

Ενωση ινδολιου και φαρμακευτικη χρηση αυτου

Info

Publication number
CY1117559T1
CY1117559T1 CY20161100462T CY161100462T CY1117559T1 CY 1117559 T1 CY1117559 T1 CY 1117559T1 CY 20161100462 T CY20161100462 T CY 20161100462T CY 161100462 T CY161100462 T CY 161100462T CY 1117559 T1 CY1117559 T1 CY 1117559T1
Authority
CY
Cyprus
Prior art keywords
indolium
union
pharmaceutical use
diseases
prophylaxis
Prior art date
Application number
CY20161100462T
Other languages
English (en)
Inventor
Teruhiko Inoue
Tetsudo Kaya
Shinichi Kikuchi
Koji Matsumura
Ritsuki Masuo
Motoya Suzuki
Michihide Maekawa
Original Assignee
Japan Tobacco, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco, Inc. filed Critical Japan Tobacco, Inc.
Publication of CY1117559T1 publication Critical patent/CY1117559T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Παρεχόμενος είναι ένας παράγων για τη θεραπεία ή την προφύλαξη φλεγμονωδών ασθενειών, αλλεργικών ασθενειών, αυτοάνοσων ασθενειών, απόρριψης μεταμόσχευσης ή των παρομοίων. Μία ένωση που αντιπροσωπεύεται με τον παρακάτω τύπο [I] ή φαρμακευτικώς αποδεκτό άλας αυτής, ή διαλύτωμα αυτής: όπου έκαστο σύμβολο είναι όπως περιγράφεται στην προδιαγραφή.
CY20161100462T 2009-11-25 2016-05-26 Ενωση ινδολιου και φαρμακευτικη χρηση αυτου CY1117559T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2009268040 2009-11-25
EP10833248.7A EP2505586B1 (en) 2009-11-25 2010-11-25 Indole compound and pharmaceutical use thereof

Publications (1)

Publication Number Publication Date
CY1117559T1 true CY1117559T1 (el) 2017-04-26

Family

ID=44066507

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20161100462T CY1117559T1 (el) 2009-11-25 2016-05-26 Ενωση ινδολιου και φαρμακευτικη χρηση αυτου

Country Status (31)

Country Link
US (6) US8299070B2 (el)
EP (3) EP2505586B1 (el)
JP (6) JP5734628B2 (el)
KR (1) KR101766502B1 (el)
CN (1) CN102712624B (el)
AR (1) AR079164A1 (el)
AU (1) AU2010323579C1 (el)
BR (1) BR112012012529B1 (el)
CA (1) CA2781660C (el)
CL (1) CL2012001328A1 (el)
CO (1) CO6541645A2 (el)
CY (1) CY1117559T1 (el)
DK (1) DK2505586T3 (el)
ES (1) ES2572935T3 (el)
HK (1) HK1174025A1 (el)
HR (1) HRP20160579T1 (el)
HU (1) HUE028016T2 (el)
IL (1) IL220009A (el)
ME (1) ME02447B (el)
MX (1) MX2012006017A (el)
MY (1) MY161095A (el)
NZ (1) NZ600840A (el)
PE (1) PE20121358A1 (el)
PL (1) PL2505586T3 (el)
PT (1) PT2505586E (el)
RS (1) RS54910B1 (el)
RU (1) RU2556216C2 (el)
SI (1) SI2505586T1 (el)
SM (1) SMT201600258B (el)
TW (1) TWI491591B (el)
WO (1) WO2011065402A1 (el)

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CN103804363A (zh) * 2012-11-14 2014-05-21 韩冰 一类具有神经保护作用的化合物及其用途
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Also Published As

Publication number Publication date
JP2015172051A (ja) 2015-10-01
HRP20160579T1 (hr) 2016-07-29
CN102712624B (zh) 2014-06-04
CA2781660C (en) 2018-06-26
MX2012006017A (es) 2012-06-25
US20110306599A1 (en) 2011-12-15
ES2572935T3 (es) 2016-06-03
PL2505586T3 (pl) 2016-12-30
KR101766502B1 (ko) 2017-08-08
PE20121358A1 (es) 2012-10-23
JP2017039761A (ja) 2017-02-23
EP3766877A1 (en) 2021-01-20
RU2556216C2 (ru) 2015-07-10
US20170267662A1 (en) 2017-09-21
EP3059234A1 (en) 2016-08-24
US8299070B2 (en) 2012-10-30
JP5734628B2 (ja) 2015-06-17
JP2018158935A (ja) 2018-10-11
AU2010323579B2 (en) 2016-05-19
JP2011132222A (ja) 2011-07-07
MY161095A (en) 2017-04-14
RS54910B1 (sr) 2016-10-31
US20200255408A1 (en) 2020-08-13
AR079164A1 (es) 2011-12-28
AU2010323579C1 (en) 2016-11-03
IL220009A (en) 2017-08-31
HK1174025A1 (zh) 2013-05-31
CL2012001328A1 (es) 2012-10-05
CA2781660A1 (en) 2011-06-03
US20210284627A1 (en) 2021-09-16
IL220009A0 (en) 2012-07-31
PT2505586E (pt) 2016-06-03
RU2012126129A (ru) 2013-12-27
SMT201600258B (it) 2016-08-31
CO6541645A2 (es) 2012-10-16
US20180362506A1 (en) 2018-12-20
JP2021091718A (ja) 2021-06-17
EP2505586B1 (en) 2016-03-02
KR20120096540A (ko) 2012-08-30
WO2011065402A1 (ja) 2011-06-03
BR112012012529A2 (pt) 2016-05-03
US20130116240A1 (en) 2013-05-09
JP2020079276A (ja) 2020-05-28
HUE028016T2 (en) 2016-11-28
NZ600840A (en) 2014-01-31
CN102712624A (zh) 2012-10-03
TWI491591B (zh) 2015-07-11
DK2505586T3 (en) 2016-05-30
ME02447B (me) 2016-09-20
TW201124378A (en) 2011-07-16
EP2505586A4 (en) 2013-05-15
SI2505586T1 (sl) 2016-08-31
AU2010323579A1 (en) 2012-07-19
BR112012012529B1 (pt) 2021-10-26
EP2505586A1 (en) 2012-10-03

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