ES2898695T8 - Derivados de benzoxaborol para el tratamiento de infecciones bacterianas - Google Patents
Derivados de benzoxaborol para el tratamiento de infecciones bacterianasInfo
- Publication number
- ES2898695T8 ES2898695T8 ES17176654T ES17176654T ES2898695T8 ES 2898695 T8 ES2898695 T8 ES 2898695T8 ES 17176654 T ES17176654 T ES 17176654T ES 17176654 T ES17176654 T ES 17176654T ES 2898695 T8 ES2898695 T8 ES 2898695T8
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- bacterial infections
- benzoxaborole derivatives
- benzoxaborole
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- GDMJXXLVTYSBBE-UHFFFAOYSA-N 1,2-benzoxaborole Chemical class C1=CC=C2OB=CC2=C1 GDMJXXLVTYSBBE-UHFFFAOYSA-N 0.000 title 1
- 208000035143 Bacterial infection Diseases 0.000 title 1
- 208000022362 bacterial infectious disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38059610P | 2010-09-07 | 2010-09-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2898695T3 ES2898695T3 (es) | 2022-03-08 |
| ES2898695T8 true ES2898695T8 (es) | 2022-03-16 |
Family
ID=44653589
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11758050.6T Active ES2635333T3 (es) | 2010-09-07 | 2011-09-07 | Derivados de benzoxaborol para tratar infecciones bacterianas |
| ES17176654T Active ES2898695T3 (es) | 2010-09-07 | 2011-09-07 | Derivados de benzoxaborol para el tratamiento de infecciones bacterianas |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11758050.6T Active ES2635333T3 (es) | 2010-09-07 | 2011-09-07 | Derivados de benzoxaborol para tratar infecciones bacterianas |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US8703742B2 (es) |
| EP (2) | EP2613788B1 (es) |
| JP (4) | JP5952280B2 (es) |
| KR (2) | KR101949423B1 (es) |
| CN (2) | CN108610356B (es) |
| AU (1) | AU2011299243C1 (es) |
| BR (1) | BR112013005426B1 (es) |
| CA (1) | CA2810021C (es) |
| CY (1) | CY1124728T1 (es) |
| DK (2) | DK2613788T3 (es) |
| EA (2) | EA033311B1 (es) |
| ES (2) | ES2635333T3 (es) |
| HK (1) | HK1247841A1 (es) |
| HR (1) | HRP20211762T1 (es) |
| HU (1) | HUE059033T2 (es) |
| IL (2) | IL225000A (es) |
| LT (1) | LT3251678T (es) |
| MX (1) | MX338209B (es) |
| PL (1) | PL3251678T3 (es) |
| PT (1) | PT3251678T (es) |
| RS (1) | RS62548B1 (es) |
| SG (2) | SG10201507032YA (es) |
| SI (1) | SI3251678T1 (es) |
| WO (1) | WO2012033858A2 (es) |
| ZA (1) | ZA201301598B (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2008131324A (ru) | 2005-12-30 | 2010-02-10 | Анакор Фармасьютикалз, Инк. (Us) | Борсодержащие малые молекулы |
| WO2011019618A1 (en) | 2009-08-14 | 2011-02-17 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
| WO2011094450A1 (en) | 2010-01-27 | 2011-08-04 | Anacor Pharmaceuticals, Inc | Boron-containing small molecules |
| EP2613788B1 (en) * | 2010-09-07 | 2017-06-21 | Anacor Pharmaceuticals, Inc. | Benzoxaborole derivatives for treating bacterial infections |
| CA2858799A1 (en) | 2011-12-22 | 2013-06-27 | Micurx Pharmaceuticals, Inc. | Tricyclic boron compounds for antimicrobial therapy |
| US11039617B2 (en) | 2013-01-30 | 2021-06-22 | Agrofresh Inc. | Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness |
| DK2950644T3 (en) | 2013-01-30 | 2017-09-04 | Agrofresh Inc | USE OF BENZOXABOROLS AS VOLATIVE ANTIMICROBIAL AGENTS IN MEAT, PLANTS OR PARTS |
| US8669207B1 (en) | 2013-01-30 | 2014-03-11 | Dow Agrosciences, Llc. | Compounds and compositions |
| US9585396B2 (en) | 2013-01-30 | 2017-03-07 | Agrofresh Inc. | Volatile applications against pathogens |
| US10070649B2 (en) | 2013-01-30 | 2018-09-11 | Agrofresh Inc. | Volatile applications against pathogens |
| WO2014121124A1 (en) | 2013-02-01 | 2014-08-07 | Anacor Pharmaceuticals, Inc. | Boron-containing small molecules as antiprotozoal agents |
| KR101636431B1 (ko) | 2013-07-30 | 2016-07-05 | 동아에스티 주식회사 | 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도 |
| PE20160752A1 (es) | 2013-08-09 | 2016-08-17 | Anacor Pharmaceuticals Inc | Compuestos de benzoxaborol triciclicos y usos de los mismos |
| EA038093B1 (ru) * | 2013-12-20 | 2021-07-05 | Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед | Способ лечения заболевания, вызванного инфекцией комплекса mycobacterium tuberculosis, с использованием (s)-(3-хлор-7,8-дигидро-2h-1,6,9-триокса-9a-борабензо[cd]азулен-2-ил)метанамина или его фармацевтически приемлемой соли |
| WO2016001834A1 (en) | 2014-07-01 | 2016-01-07 | Daiichi Sankyo Company, Limited | Tricyclic benzoxaboroles as antibacterial agents |
| MA41494B1 (fr) | 2015-02-12 | 2020-10-28 | Glaxosmithkline Ip No 2 Ltd | Composés benzoxaborole substitués en position 4 et utilisations associées |
| RS64770B1 (sr) | 2016-03-07 | 2023-11-30 | Agrofresh Inc | Sinergistički postupci upotrebe jedinjenja benzoksaborola i gasova za prezerviranje kao antimikrobnih agenasa za useve |
| EP3609504A4 (en) | 2017-03-01 | 2021-03-03 | Anacor Pharmaceuticals, Inc. | NEW OXABOROLE ANALOGUES AND USES OF THE LATEST |
| CN111655035A (zh) | 2017-11-30 | 2020-09-11 | 博瑞金股份有限公司 | 苯并氧杂硼杂环戊烯化合物和其制剂 |
| CN108727176B (zh) * | 2018-07-26 | 2021-05-18 | 荆楚理工学院 | 一种制备5-卤-2,3-二羟基苯甲醛的方法 |
| JP2021534247A (ja) | 2018-08-18 | 2021-12-09 | ボラゲン，インコーポレーテッド | 置換ベンゾキサボロールの固体形態およびその組成物 |
| US20220275007A1 (en) * | 2019-07-30 | 2022-09-01 | Boragen, Inc. | Flow reaction process for manufacture of boron-containing agrochemicals |
| CN110664756B (zh) * | 2019-10-09 | 2020-11-17 | 吉林大学 | 一种小儿外伤喷雾剂及其制备方法 |
| WO2022043936A1 (en) | 2020-08-31 | 2022-03-03 | Pfizer Inc. | Methods of protecting rna |
| EP4384527A1 (en) * | 2022-06-23 | 2024-06-19 | Micurx Pharmaceuticals, Inc. | Prodrugs of boron compounds and their use in treating bacterial infections |
| CA3239096A1 (en) * | 2022-06-23 | 2023-12-28 | Shanghai Micurx Pharmaceutical Co., Ltd. | Methods and uses of boron compounds in the treatment of nontuberculous mycobacterium infections and pharmaceutical compositions for treatment of same |
| CN115572218B (zh) * | 2022-08-29 | 2024-04-16 | 江阴勒森生物科技有限公司 | 一种2-溴-3-羟基苯甲醛及其相关化学发光底物中间体的制备方法 |
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| US2260336A (en) | 1939-10-16 | 1941-10-28 | Dow Chemical Co | Method of preparation of organic borates |
| US3686398A (en) | 1970-07-20 | 1972-08-22 | Chevron Res | 10,9-boroxarophenanthrene as fungicides |
| GB1396904A (en) | 1972-08-11 | 1975-06-11 | Ici Ltd | Method for the control of micro-organisms |
| US4602011A (en) | 1975-10-24 | 1986-07-22 | Chapman Chemical Company | Antimicrobial compositions and methods of using same |
| US4766113A (en) | 1975-10-24 | 1988-08-23 | Chapman Chemical Company | Antimicrobial compositions and methods of using same |
| US4716035A (en) | 1985-05-24 | 1987-12-29 | The Procter & Gamble Company | Oral compositions and methods for treating gingivitis |
| US5962498A (en) | 1986-06-11 | 1999-10-05 | Procyon Pharmaceuticals, Inc. | Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity |
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| BRPI0922566A2 (pt) | 2008-12-17 | 2017-03-28 | Anacor Pharmaceuticals Inc | polimorfo cristalino, composição farmacêutica, composto, e, métodos para preparar um composto, e para tratar uma doença. |
| BR112012001987A2 (pt) | 2009-07-28 | 2015-09-01 | Anacor Pharmaceuticals Inc | Composto, combinação, formulação farmacêutica, uso de um composto, uma combinação ou um sal farmaceuticamente aceitável dos mesmos, e, métodos para tratar uma infecção bacteriana, para matar ou inibir o crescimento de uma bactéria, e para inibir uma beta-lactamase. |
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-
2011
- 2011-09-07 EP EP11758050.6A patent/EP2613788B1/en active Active
- 2011-09-07 CA CA2810021A patent/CA2810021C/en active Active
- 2011-09-07 WO PCT/US2011/050728 patent/WO2012033858A2/en active Application Filing
- 2011-09-07 DK DK11758050.6T patent/DK2613788T3/en active
- 2011-09-07 BR BR112013005426-3A patent/BR112013005426B1/pt active IP Right Grant
- 2011-09-07 RS RS20211391A patent/RS62548B1/sr unknown
- 2011-09-07 AU AU2011299243A patent/AU2011299243C1/en active Active
- 2011-09-07 HR HRP20211762TT patent/HRP20211762T1/hr unknown
- 2011-09-07 PL PL17176654T patent/PL3251678T3/pl unknown
- 2011-09-07 SG SG10201507032YA patent/SG10201507032YA/en unknown
- 2011-09-07 LT LTEP17176654.6T patent/LT3251678T/lt unknown
- 2011-09-07 HU HUE17176654A patent/HUE059033T2/hu unknown
- 2011-09-07 US US13/227,444 patent/US8703742B2/en active Active
- 2011-09-07 SI SI201132017T patent/SI3251678T1/sl unknown
- 2011-09-07 MX MX2013002651A patent/MX338209B/es active IP Right Grant
- 2011-09-07 ES ES11758050.6T patent/ES2635333T3/es active Active
- 2011-09-07 SG SG2013014493A patent/SG187969A1/en unknown
- 2011-09-07 ES ES17176654T patent/ES2898695T3/es active Active
- 2011-09-07 DK DK17176654.6T patent/DK3251678T3/da active
- 2011-09-07 JP JP2013527375A patent/JP5952280B2/ja active Active
- 2011-09-07 EA EA201791850A patent/EA033311B1/ru unknown
- 2011-09-07 CN CN201810051113.2A patent/CN108610356B/zh active Active
- 2011-09-07 EP EP17176654.6A patent/EP3251678B1/en active Active
- 2011-09-07 CN CN2011800427618A patent/CN103140228A/zh active Pending
- 2011-09-07 EA EA201390274A patent/EA028743B1/ru not_active IP Right Cessation
- 2011-09-07 KR KR1020137005717A patent/KR101949423B1/ko active IP Right Grant
- 2011-09-07 PT PT171766546T patent/PT3251678T/pt unknown
- 2011-09-07 KR KR1020197003860A patent/KR102152901B1/ko active IP Right Grant
-
2013
- 2013-02-28 IL IL225000A patent/IL225000A/en active IP Right Grant
- 2013-03-01 ZA ZA2013/01598A patent/ZA201301598B/en unknown
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2014
- 2014-03-21 US US14/221,637 patent/US9751898B2/en active Active
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2016
- 2016-03-13 IL IL244556A patent/IL244556B/en active IP Right Grant
- 2016-06-09 JP JP2016114971A patent/JP2016199558A/ja not_active Withdrawn
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2017
- 2017-08-24 US US15/685,846 patent/US20170355719A1/en not_active Abandoned
- 2017-10-06 JP JP2017195759A patent/JP6491294B2/ja active Active
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2018
- 2018-06-06 HK HK18107388.5A patent/HK1247841A1/zh unknown
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2019
- 2019-02-28 JP JP2019035145A patent/JP2019112431A/ja active Pending
- 2019-07-30 US US16/526,248 patent/US11008345B2/en active Active
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2021
- 2021-11-16 CY CY20211100990T patent/CY1124728T1/el unknown
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